{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T01:10:55Z","timestamp":1785892255703,"version":"3.56.0"},"reference-count":31,"publisher":"Royal Society of Chemistry (RSC)","issue":"20","license":[{"start":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T00:00:00Z","timestamp":1682294400000},"content-version":"vor","delay-in-days":113,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CHE-1900050"],"award-info":[{"award-number":["CHE-1900050"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CHE-2154854"],"award-info":[{"award-number":["CHE-2154854"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CHE-1725028"],"award-info":[{"award-number":["CHE-1725028"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["S10OD021486"],"award-info":[{"award-number":["S10OD021486"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Sci."],"abstract":"<jats:p>\n                    A nitrogen-interrupted\n                    <jats:italic>halo<\/jats:italic>\n                    -Prins\/\n                    <jats:italic>halo<\/jats:italic>\n                    -Nazarov fragment coupling cascade is reported. The method couples simple building blocks to produce functionalized indolines with up to four contiguous stereocenters.\n                  <\/jats:p>","DOI":"10.1039\/d3sc00986f","type":"journal-article","created":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T11:21:09Z","timestamp":1682335269000},"page":"5431-5437","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Nitrogen-interrupted\n                    <i>halo<\/i>\n                    -Prins\/\n                    <i>halo<\/i>\n                    -Nazarov fragment coupling cascade for the synthesis of indolines"],"prefix":"10.1039","volume":"14","author":[{"given":"Aleksa","family":"Milosavljevic","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Rochester, Rochester, NY, USA, 14627-0216"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Connor","family":"Holt","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Rochester, Rochester, NY, USA, 14627-0216"},{"name":"Worldwide Research and Development, Pfizer, Inc., Eastern Point Road, Groton, Connecticut 06340, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5560-7414","authenticated-orcid":false,"given":"Alison J.","family":"Frontier","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Rochester, Rochester, NY, USA, 14627-0216"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2023]]},"reference":[{"key":"D3SC00986F\/cit1\/1","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.3390\/molecules25081909","volume":"25","author":"Kerru","year":"2020","journal-title":"Molecules"},{"key":"D3SC00986F\/cit2\/1","doi-asserted-by":"crossref","first-page":"10257","DOI":"10.1021\/jm501100b","volume":"57","author":"Vitaku","year":"2014","journal-title":"J. Med. Chem."},{"key":"D3SC00986F\/cit3\/1","doi-asserted-by":"crossref","first-page":"18576","DOI":"10.1039\/C8RA03480J","volume":"8","author":"Vivekanand","year":"2018","journal-title":"RSC Adv."},{"key":"D3SC00986F\/cit4\/1","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1039\/c2md20347b","volume":"4","author":"Lovering","year":"2013","journal-title":"MedChemComm"},{"key":"D3SC00986F\/cit5a\/1","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1002\/adsc.201901001","volume":"362","author":"Yadykov","year":"2020","journal-title":"Adv. Synth. Catal."},{"key":"D3SC00986F\/cit5b\/1","doi-asserted-by":"crossref","first-page":"5676","DOI":"10.1039\/b908515g","author":"Grant","year":"2009","journal-title":"Chem. Commun."},{"key":"D3SC00986F\/cit5c\/1","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1021\/acs.accounts.0c00284","volume":"53","author":"Frontier","year":"2020","journal-title":"Acc. Chem. Res."},{"key":"D3SC00986F\/cit6a\/1","doi-asserted-by":"crossref","first-page":"12472","DOI":"10.1021\/ja053393g","volume":"127","author":"Dhoro","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"D3SC00986F\/cit6b\/1","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1021\/ol070053m","volume":"9","author":"Rostami","year":"2007","journal-title":"Org. Lett."},{"key":"D3SC00986F\/cit6c\/1","doi-asserted-by":"crossref","first-page":"7256","DOI":"10.1021\/ja0718873","volume":"129","author":"Dhoro","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"D3SC00986F\/cit6d\/1","doi-asserted-by":"crossref","first-page":"12019","DOI":"10.1021\/ja071041z","volume":"129","author":"Song","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"D3SC00986F\/cit6e\/1","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1021\/ol102651k","volume":"13","author":"Scadeng","year":"2011","journal-title":"Org. Lett."},{"key":"D3SC00986F\/cit6f\/1","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1039\/C5SC03559G","volume":"7","author":"William","year":"2016","journal-title":"Chem. Sci."},{"key":"D3SC00986F\/cit6g\/1","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1039\/C5CC08596A","volume":"52","author":"Wang","year":"2016","journal-title":"Chem. Commun."},{"key":"D3SC00986F\/cit7a\/1","doi-asserted-by":"crossref","first-page":"15030","DOI":"10.1002\/anie.201709482","volume":"56","author":"Alachouzos","year":"2017","journal-title":"Angew. Chem., Int. Ed."},{"key":"D3SC00986F\/cit7b\/1","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1021\/jacs.8b11713","volume":"141","author":"Alachouzos","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"D3SC00986F\/cit7c\/1","doi-asserted-by":"crossref","first-page":"4010","DOI":"10.1021\/acs.orglett.0c01330","volume":"22","author":"Alachouzos","year":"2020","journal-title":"Org. Lett."},{"key":"D3SC00986F\/cit8\/1","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1021\/cr0300587","volume":"106","author":"Ribi\u00e8re","year":"2006","journal-title":"Chem. Rev."},{"key":"D3SC00986F\/cit9\/1","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1021\/ol4031606","volume":"16","author":"Miller","year":"2014","journal-title":"Org. Lett."},{"key":"D3SC00986F\/cit10\/1","doi-asserted-by":"crossref","first-page":"5461","DOI":"10.1021\/jacs.9b00198","volume":"141","author":"Holt","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"D3SC00986F\/cit11a\/1","volume-title":"Encycl. Reag. Org. Synth.","author":"Concepcion","year":"2018","unstructured":"A. B.Concepcion ,  H.Yamamoto ,  R. K.Boeckman Jr ,  K. F.Biegasiewicz  and  D. J.Tusch , in  Encycl. Reag. Org. Synth. ,  John Wiley & Sons, Ltd ,  2018"},{"key":"D3SC00986F\/cit11b\/1","volume-title":"Encycl. Reag. Org. Synth.","author":"Taschner","year":"2001","unstructured":"M. J.Taschner , in  Encycl. Reag. Org. Synth. ,  John Wiley & Sons, Ltd ,  2001"},{"key":"D3SC00986F\/cit12\/1","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1055\/s-0039-1690869","volume":"52","author":"Abdul-Rashed","year":"2020","journal-title":"Synthesis"},{"key":"D3SC00986F\/cit19\/1","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/nchem.1669","volume":"5","author":"Collins","year":"2013","journal-title":"Nat. Chem."},{"key":"D3SC00986F\/cit20a\/1","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1021\/ol026125l","volume":"4","author":"Ma","year":"2002","journal-title":"Org. Lett."},{"key":"D3SC00986F\/cit20b\/1","doi-asserted-by":"crossref","first-page":"9250","DOI":"10.1002\/anie.201005156","volume":"49","author":"Shi","year":"2010","journal-title":"Angew. Chem., Int. Ed."},{"key":"D3SC00986F\/cit20c\/1","doi-asserted-by":"crossref","first-page":"15619","DOI":"10.1002\/chem.201603880","volume":"22","author":"Johnson","year":"2016","journal-title":"Chem.\u2013Eur. J."},{"key":"D3SC00986F\/cit20d\/1","doi-asserted-by":"crossref","first-page":"5836","DOI":"10.1002\/anie.201301087","volume":"52","author":"Mace","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"D3SC00986F\/cit20e\/1","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1039\/C6CY02623K","volume":"7","author":"Sytniczuk","year":"2017","journal-title":"Catal. Sci. Technol."},{"key":"D3SC00986F\/cit20f\/1","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1021\/ol300617r","volume":"14","author":"Willand-Charnley","year":"2012","journal-title":"Org. Lett."},{"key":"D3SC00986F\/cit20g\/1","doi-asserted-by":"crossref","first-page":"9059","DOI":"10.1021\/acs.orglett.0c03444","volume":"22","author":"Xu","year":"2020","journal-title":"Org. Lett."}],"container-title":["Chemical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2023\/SC\/D3SC00986F","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2023\/SC\/D3SC00986F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:56:33Z","timestamp":1782885393000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/sc\/article\/14\/20\/5431-5437\/826846"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":31,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2023,5,24]]}},"URL":"https:\/\/doi.org\/10.1039\/d3sc00986f","relation":{},"ISSN":["2041-6520","2041-6539"],"issn-type":[{"value":"2041-6520","type":"print"},{"value":"2041-6539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}