{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T07:15:16Z","timestamp":1782890116824,"version":"3.54.5"},"reference-count":72,"publisher":"Royal Society of Chemistry (RSC)","issue":"20","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"am","delay-in-days":605,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61871121"],"award-info":[{"award-number":["61871121"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Analyst"],"abstract":"<jats:p>An effective method to characterize full-length circRNA sequences from low-input RNA samples with rolling circular reverse transcription and nanopore sequencing.<\/jats:p>","DOI":"10.1039\/d4an00715h","type":"journal-article","created":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T22:01:30Z","timestamp":1724796090000},"page":"5118-5130","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Full-length circRNA sequencing method using low-input RNAs and profiling of circRNAs in MPTP-PD mice on a nanopore platform"],"prefix":"10.1039","volume":"149","author":[{"given":"Ying","family":"Wang","sequence":"first","affiliation":[{"name":"State Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohan","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China"},{"name":"Hebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0193-1504","authenticated-orcid":false,"given":"Wenxiang","family":"Lu","sequence":"additional","affiliation":[{"name":"State Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuyu","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingsong","family":"Yao","sequence":"additional","affiliation":[{"name":"State Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1678-5960","authenticated-orcid":false,"given":"Zhiyu","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huajuan","family":"Shi","sequence":"additional","affiliation":[{"name":"State Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weizhong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4088-4117","authenticated-orcid":false,"given":"Yunfei","family":"Bai","sequence":"additional","affiliation":[{"name":"State Key Lab of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D4AN00715H\/cit1\/1","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/nature11928","volume":"495","author":"Memczak","year":"2013","journal-title":"Nature"},{"key":"D4AN00715H\/cit2\/1","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/j.molcel.2015.03.027","volume":"58","author":"Rybak-Wolf","year":"2015","journal-title":"Mol. Cell"},{"key":"D4AN00715H\/cit3\/1","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/s41421-018-0050-1","volume":"4","author":"Xu","year":"2018","journal-title":"Cell Discovery"},{"key":"D4AN00715H\/cit4\/1","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1038\/s41576-019-0158-7","volume":"20","author":"Kristensen","year":"2019","journal-title":"Nat. Rev. Genet."},{"key":"D4AN00715H\/cit5\/1","doi-asserted-by":"crossref","first-page":"e87","DOI":"10.1093\/nar\/gkw075","volume":"44","author":"Song","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"D4AN00715H\/cit6\/1","doi-asserted-by":"crossref","first-page":"5156","DOI":"10.1007\/s12035-016-0055-4","volume":"54","author":"Floris","year":"2017","journal-title":"Mol. Neurobiol."},{"key":"D4AN00715H\/cit7\/1","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1159\/000494478","volume":"50","author":"Yang","year":"2018","journal-title":"Cell. Physiol. Biochem."},{"key":"D4AN00715H\/cit8\/1","doi-asserted-by":"crossref","first-page":"e11942","DOI":"10.15252\/emmm.201911942","volume":"12","author":"Hanan","year":"2020","journal-title":"EMBO Mol. Med."},{"key":"D4AN00715H\/cit9\/1","doi-asserted-by":"crossref","first-page":"5265","DOI":"10.1016\/j.ygeno.2020.09.042","volume":"112","author":"Curry-Hyde","year":"2020","journal-title":"Genomics"},{"issue":"1","key":"D4AN00715H\/cit10\/1","doi-asserted-by":"crossref","first-page":"540","DOI":"10.3892\/mmr.2021.12179","volume":"24","author":"Wang","year":"2021","journal-title":"Mol. Med. Rep."},{"key":"D4AN00715H\/cit11\/1","doi-asserted-by":"crossref","first-page":"6914","DOI":"10.1007\/s12035-018-0903-5","volume":"55","author":"Kumar","year":"2018","journal-title":"Mol. Neurobiol."},{"key":"D4AN00715H\/cit12\/1","doi-asserted-by":"crossref","first-page":"3444","DOI":"10.1016\/j.celrep.2019.02.078","volume":"26","author":"Ji","year":"2019","journal-title":"Cell Rep."},{"key":"D4AN00715H\/cit13\/1","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/nn.3975","volume":"18","author":"You","year":"2015","journal-title":"Nat. Neurosci."},{"key":"D4AN00715H\/cit14\/1","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1080\/15476286.2016.1255398","volume":"14","author":"Hanan","year":"2017","journal-title":"RNA Biol."},{"key":"D4AN00715H\/cit15\/1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/s41531-021-00265-9","volume":"8","author":"Doxakis","year":"2022","journal-title":"npj Parkinson's Dis."},{"key":"D4AN00715H\/cit16\/1","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1080\/15548627.2023.2196889","volume":"19","author":"Zhou","year":"2023","journal-title":"Autophagy"},{"key":"D4AN00715H\/cit17\/1","doi-asserted-by":"crossref","first-page":"102430","DOI":"10.1016\/j.redox.2022.102430","volume":"56","author":"Cheng","year":"2022","journal-title":"Redox Biol."},{"key":"D4AN00715H\/cit18\/1","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.3390\/ijms21083006","volume":"21","author":"Jia","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"D4AN00715H\/cit19\/1","doi-asserted-by":"crossref","first-page":"e11942","DOI":"10.15252\/emmm.201911942","volume":"12","author":"Hanan","year":"2020","journal-title":"EMBO Mol. Med."},{"key":"D4AN00715H\/cit20\/1","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.cell.2014.09.001","volume":"159","author":"Zhang","year":"2014","journal-title":"Cell"},{"key":"D4AN00715H\/cit21\/1","doi-asserted-by":"crossref","first-page":"e178","DOI":"10.1093\/nar\/gkq622","volume":"38","author":"Wang","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"D4AN00715H\/cit22\/1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s13059-014-0571-3","volume":"16","author":"Gao","year":"2015","journal-title":"Genome Biol."},{"key":"D4AN00715H\/cit23\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13073-019-0614-1","volume":"11","author":"Zheng","year":"2019","journal-title":"Genome Med."},{"key":"D4AN00715H\/cit24\/1","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.gpb.2019.03.004","volume":"17","author":"Wu","year":"2019","journal-title":"Genomics, Proteomics Bioinf."},{"key":"D4AN00715H\/cit25\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-021-24975-z","volume":"12","author":"Rahimi","year":"2021","journal-title":"Nat. Commun."},{"key":"D4AN00715H\/cit26\/1","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.gendis.2023.04.013","volume":"11","author":"Papatsirou","year":"2024","journal-title":"Genes Dis."},{"key":"D4AN00715H\/cit27\/1","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41467-020-20459-8","volume":"12","author":"Xin","year":"2021","journal-title":"Nat. Commun."},{"key":"D4AN00715H\/cit28\/1","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1038\/s41587-021-00842-6","volume":"39","author":"Zhang","year":"2021","journal-title":"Nat. Biotechnol."},{"key":"D4AN00715H\/cit29\/1","doi-asserted-by":"crossref","first-page":"e69457","DOI":"10.7554\/eLife.69457","volume":"10","author":"Liu","year":"2021","journal-title":"eLife"},{"key":"D4AN00715H\/cit30\/1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ymeth.2021.09.010","volume":"196","author":"Rahimi","year":"2021","journal-title":"Methods"},{"key":"D4AN00715H\/cit31\/1","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1038\/s41596-023-00815-w","volume":"18","author":"Hou","year":"2023","journal-title":"Nat. Protoc."},{"key":"D4AN00715H\/cit32\/1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s13059-018-1417-1","volume":"19","author":"Trincado","year":"2018","journal-title":"Genome Biol."},{"key":"D4AN00715H\/cit33\/1","doi-asserted-by":"crossref","first-page":"12060","DOI":"10.1038\/ncomms12060","volume":"7","author":"Gao","year":"2016","journal-title":"Nat. Commun."},{"key":"D4AN00715H\/cit34\/1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s12943-017-0630-y","volume":"16","author":"Liu","year":"2017","journal-title":"Mol. Cancer"},{"key":"D4AN00715H\/cit35\/1","doi-asserted-by":"crossref","first-page":"D163","DOI":"10.1093\/nar\/gkq1107","volume":"39","author":"Hsu","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"D4AN00715H\/cit36\/1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.jgg.2018.07.006","volume":"45","author":"Zhao","year":"2018","journal-title":"J. Genet. Genomics"},{"key":"D4AN00715H\/cit37\/1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0378-1119(01)00819-8","volume":"282","author":"Rombel","year":"2002","journal-title":"Gene"},{"key":"D4AN00715H\/cit38\/1","doi-asserted-by":"crossref","first-page":"e74","DOI":"10.1093\/nar\/gkt006","volume":"41","author":"Wang","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"D4AN00715H\/cit39\/1","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s13059-020-02012-4","volume":"21","author":"Liu","year":"2020","journal-title":"Genome Biol."},{"key":"D4AN00715H\/cit40\/1","first-page":"100141","volume":"2","author":"Wu","year":"2021","journal-title":"Innovation"},{"key":"D4AN00715H\/cit41\/1","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/S1474-4422(19)30320-5","volume":"18","author":"Nalls","year":"2019","journal-title":"Lancet Neurol."},{"key":"D4AN00715H\/cit42\/1","doi-asserted-by":"crossref","first-page":"3678","DOI":"10.1038\/srep03678","volume":"4","author":"Bhargava","year":"2014","journal-title":"Sci. Rep."},{"key":"D4AN00715H\/cit43\/1","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1093\/brain\/awab446","volume":"145","author":"Smajic","year":"2022","journal-title":"Brain"},{"key":"D4AN00715H\/cit44\/1","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/nsmb.2959","volume":"22","author":"Li","year":"2015","journal-title":"Nat. Struct. Mol. Biol."},{"key":"D4AN00715H\/cit45\/1","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.nbd.2005.07.010","volume":"21","author":"Miller","year":"2006","journal-title":"Neurobiol. Dis."},{"key":"D4AN00715H\/cit46\/1","doi-asserted-by":"crossref","first-page":"e102909","DOI":"10.1371\/journal.pone.0102909","volume":"9","author":"Riley","year":"2014","journal-title":"PLoS One"},{"key":"D4AN00715H\/cit47\/1","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/s13059-022-02621-1","volume":"23","author":"Li","year":"2022","journal-title":"Genome Biol."},{"key":"D4AN00715H\/cit48\/1","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1038\/nature11993","volume":"495","author":"Hansen","year":"2013","journal-title":"Nature"},{"key":"D4AN00715H\/cit49\/1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s13059-021-02300-7","volume":"22","author":"Li","year":"2021","journal-title":"Genome Biol."},{"issue":"1786","key":"D4AN00715H\/cit50\/1","doi-asserted-by":"crossref","first-page":"20190097","DOI":"10.1098\/rstb.2019.0097","volume":"374","author":"Byrne","year":"2019","journal-title":"Philos. Trans. R. Soc., B"},{"key":"D4AN00715H\/cit51\/1","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/s41418-022-00948-7","volume":"29","author":"Misir","year":"2022","journal-title":"Cell Death Differ."},{"issue":"8","key":"D4AN00715H\/cit52\/1","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.3390\/pharmaceutics15082035","volume":"15","author":"Titze-de-Almeida","year":"2023","journal-title":"Pharmaceutics"},{"key":"D4AN00715H\/cit53\/1","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/s41419-022-04934-2","volume":"13","author":"Liu","year":"2022","journal-title":"Cell Death Dis."},{"key":"D4AN00715H\/cit54\/1","doi-asserted-by":"crossref","first-page":"e52072","DOI":"10.15252\/embr.202052072","volume":"22","author":"Dodbele","year":"2021","journal-title":"EMBO Rep."},{"key":"D4AN00715H\/cit55\/1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1136\/bjo.2007.124008","volume":"92","author":"Robson","year":"2008","journal-title":"Br. J. Ophthalmol."},{"issue":"5","key":"D4AN00715H\/cit56\/1","doi-asserted-by":"crossref","first-page":"e202304042","DOI":"10.1083\/jcb.202304042","volume":"223","author":"Schr\u00f6der","year":"2024","journal-title":"J. Cell Biol."},{"issue":"1","key":"D4AN00715H\/cit57\/1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3390\/diseases7010022","volume":"7","author":"Matsuda","year":"2019","journal-title":"Diseases"},{"key":"D4AN00715H\/cit58\/1","doi-asserted-by":"crossref","first-page":"6849","DOI":"10.1093\/nar\/gkab523","volume":"49","author":"Knupp","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"D4AN00715H\/cit59\/1","first-page":"376","volume":"34","author":"Zhong","year":"2024","journal-title":"Genome Res."},{"key":"D4AN00715H\/cit60\/1","doi-asserted-by":"crossref","first-page":"2846","DOI":"10.1093\/nar\/gkw027","volume":"44","author":"Du","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"D4AN00715H\/cit61\/1","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1080\/15476286.2017.1279788","volume":"14","author":"Abdelmohsen","year":"2017","journal-title":"RNA Biol."},{"issue":"6357","key":"D4AN00715H\/cit62\/1","doi-asserted-by":"crossref","first-page":"eaam8526","DOI":"10.1126\/science.aam8526","volume":"357","author":"Piwecka","year":"2017","journal-title":"Science"},{"issue":"10","key":"D4AN00715H\/cit63\/1","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.3390\/cells9102196","volume":"9","author":"Mo","year":"2020","journal-title":"Cells"},{"key":"D4AN00715H\/cit64\/1","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/cr.2017.31","volume":"27","author":"Yang","year":"2017","journal-title":"Cell Res."},{"key":"D4AN00715H\/cit65\/1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/nrm.2015.32","volume":"17","author":"Chen","year":"2016","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"D4AN00715H\/cit66\/1","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/nbt.2890","volume":"32","author":"Jeck","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"D4AN00715H\/cit67\/1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s12974-018-1100-1","volume":"15","author":"Neal","year":"2018","journal-title":"J. Neuroinflammation"},{"key":"D4AN00715H\/cit68\/1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1515\/revneuro-2011-0063","volume":"23","author":"Wang","year":"2012","journal-title":"Rev. Neurosci."},{"key":"D4AN00715H\/cit69\/1","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1073\/pnas.1219987110","volume":"110","author":"Lee","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D4AN00715H\/cit70\/1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.molcel.2017.02.017","volume":"66","author":"Legnini","year":"2017","journal-title":"Mol. Cell"},{"key":"D4AN00715H\/cit71\/1","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.celrep.2016.12.043","volume":"18","author":"Qin","year":"2017","journal-title":"Cell Rep."},{"key":"D4AN00715H\/cit72\/1","doi-asserted-by":"crossref","first-page":"e2935","DOI":"10.1002\/brb3.2935","volume":"13","author":"Chen","year":"2023","journal-title":"Brain Behav."}],"container-title":["The Analyst"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/AN\/D4AN00715H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:36:45Z","timestamp":1782884205000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/an\/article\/149\/20\/5118-5130\/836438"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":72,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2024,10,7]]}},"URL":"https:\/\/doi.org\/10.1039\/d4an00715h","relation":{},"ISSN":["0003-2654","1364-5528"],"issn-type":[{"value":"0003-2654","type":"print"},{"value":"1364-5528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}