{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T18:11:10Z","timestamp":1782929470769,"version":"3.54.5"},"reference-count":33,"publisher":"Royal Society of Chemistry (RSC)","issue":"13","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"am","delay-in-days":429,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["DUT24MS018"],"award-info":[{"award-number":["DUT24MS018"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005047","name":"Natural Science Foundation of Liaoning Province","doi-asserted-by":"publisher","award":["2023-MSBA-018"],"award-info":[{"award-number":["2023-MSBA-018"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002980","name":"Dalian University of Technology","doi-asserted-by":"publisher","award":["2024-ZLKF-33"],"award-info":[{"award-number":["2024-ZLKF-33"]}],"id":[{"id":"10.13039\/501100002980","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Anal. Methods"],"abstract":"<jats:p>\n                    Determination of PA-PEG\n                    <jats:sub>8<\/jats:sub>\n                    -PA polymers by UPLC-MS\/MS.\n                  <\/jats:p>","DOI":"10.1039\/d4ay02050b","type":"journal-article","created":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T03:41:13Z","timestamp":1741232473000},"page":"2676-2685","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Development of a UPLC-MS\/MS assay for determination of PA-PEG\n                    <sub>8<\/sub>\n                    -PA polymers in rat plasma coupled with [M \u2212 H]\n                    <sup>\u2212<\/sup>\n                    to enhance sensitivity"],"prefix":"10.1039","volume":"17","author":[{"given":"Jiye","family":"Tian","sequence":"first","affiliation":[{"name":"Cancer Hospital of Dalian University of Technology, Dalian University of Technology, Shenyang, 110042, China"},{"name":"School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, Liaoning, 124221, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunpeng","family":"Feng","sequence":"additional","affiliation":[{"name":"School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, Liaoning, 124221, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Xue","sequence":"additional","affiliation":[{"name":"School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, Liaoning, 124221, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiansong","family":"You","sequence":"additional","affiliation":[{"name":"Aim Honesty Biopharmaceutical Co., Ltd, Dalian, Liaoning, 116600, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiyun","family":"Shi","sequence":"additional","affiliation":[{"name":"Cancer Hospital of Dalian University of Technology, Dalian University of Technology, Shenyang, 110042, China"},{"name":"School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, Liaoning, 124221, China"},{"name":"Aim Honesty Biopharmaceutical Co., Ltd, Dalian, Liaoning, 116600, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8068-5999","authenticated-orcid":false,"given":"Lei","family":"Yin","sequence":"additional","affiliation":[{"name":"Cancer Hospital of Dalian University of Technology, Dalian University of Technology, Shenyang, 110042, China"},{"name":"School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, Panjin, Liaoning, 124221, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D4AY02050B\/cit1\/1","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.jmbbm.2014.06.003","volume":"38","author":"Kobayashi","year":"2014","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"D4AY02050B\/cit2\/1","doi-asserted-by":"publisher","first-page":"8163","DOI":"10.1021\/jf301442p","volume":"60","author":"Castro L\u00f3pez Mdel","year":"2012","journal-title":"J. Agric. Food Chem."},{"key":"D4AY02050B\/cit3\/1","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.jconrel.2022.09.031","volume":"351","author":"Ibrahim","year":"2022","journal-title":"J. Controlled Release"},{"key":"D4AY02050B\/cit4\/1","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1007\/s11095-013-1067-7","volume":"30","author":"Schellekens","year":"2013","journal-title":"Pharm. Res."},{"key":"D4AY02050B\/cit5\/1","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1080\/14686996.2019.1627174","volume":"20","author":"Mohamed","year":"2019","journal-title":"Sci. Technol. Adv. Mater."},{"key":"D4AY02050B\/cit6\/1","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1517\/17425247.2012.720969","volume":"9","author":"Garay","year":"2012","journal-title":"Expert Opin. Drug Delivery"},{"key":"D4AY02050B\/cit7\/1","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.addr.2020.07.024","volume":"154\u2013155","author":"Kozma","year":"2020","journal-title":"Adv. Drug Delivery Rev."},{"key":"D4AY02050B\/cit8\/1","doi-asserted-by":"publisher","first-page":"115044","DOI":"10.1016\/j.addr.2023.115044","volume":"200","author":"Guo","year":"2023","journal-title":"Adv. Drug Delivery Rev."},{"key":"D4AY02050B\/cit9\/1","doi-asserted-by":"publisher","first-page":"e2302712","DOI":"10.1002\/adhm.202302712","volume":"13","author":"Berger","year":"2024","journal-title":"Adv. Healthc. Mater."},{"key":"D4AY02050B\/cit10\/1","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1016\/j.carbpol.2016.06.020","volume":"151","author":"Chudasama","year":"2016","journal-title":"Carbohydr. Polym."},{"key":"D4AY02050B\/cit11\/1","doi-asserted-by":"publisher","first-page":"39119","DOI":"10.1038\/srep39119","volume":"6","author":"Hsieh","year":"2016","journal-title":"Sci. Rep."},{"key":"D4AY02050B\/cit12\/1","doi-asserted-by":"publisher","first-page":"2355","DOI":"10.1021\/ac902548m","volume":"82","author":"Chuang","year":"2010","journal-title":"Anal. Chem."},{"key":"D4AY02050B\/cit13\/1","doi-asserted-by":"publisher","first-page":"746480","DOI":"10.3389\/fchem.2021.746480","volume":"9","author":"Ciolino","year":"2021","journal-title":"Front. Chem."},{"key":"D4AY02050B\/cit14\/1","doi-asserted-by":"publisher","first-page":"115613","DOI":"10.1016\/j.jpba.2023.115613","volume":"235","author":"Huang","year":"2023","journal-title":"J. Pharm. Biomed. Anal."},{"key":"D4AY02050B\/cit15\/1","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.jpba.2019.03.066","volume":"171","author":"Khandelwal","year":"2019","journal-title":"J. Pharm. Biomed. Anal."},{"key":"D4AY02050B\/cit16\/1","doi-asserted-by":"publisher","first-page":"3730","DOI":"10.1021\/acs.analchem.5b04565","volume":"88","author":"Alvares","year":"2016","journal-title":"Anal. Chem."},{"key":"D4AY02050B\/cit17\/1","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.jchromb.2004.02.033","volume":"805","author":"Loret","year":"2004","journal-title":"J. Chromatogr., B: Anal. Technol. Biomed. Life Sci."},{"key":"D4AY02050B\/cit18\/1","doi-asserted-by":"publisher","first-page":"122888","DOI":"10.1016\/j.envpol.2023.122888","volume":"340","author":"Tarring","year":"2024","journal-title":"Environ. Pollut."},{"key":"D4AY02050B\/cit19\/1","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1006\/abio.2000.4733","volume":"285","author":"Chung","year":"2000","journal-title":"Anal. Biochem."},{"key":"D4AY02050B\/cit20\/1","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/s0003-2697(02)00593-6","volume":"313","author":"Li","year":"2003","journal-title":"Anal. Biochem."},{"key":"D4AY02050B\/cit21\/1","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1002\/rcm.5000","volume":"25","author":"Basavaraj","year":"2011","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"D4AY02050B\/cit22\/1","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1097\/ftd.0000000000001130","volume":"45","author":"De Gregori","year":"2023","journal-title":"Ther. Drug Monit."},{"key":"D4AY02050B\/cit23\/1","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/978-1-4939-7352-1_5","volume":"1682","author":"Smith","year":"2018","journal-title":"Methods Mol. Biol."},{"key":"D4AY02050B\/cit24\/1","doi-asserted-by":"publisher","first-page":"113967","DOI":"10.1016\/j.jpba.2021.113967","volume":"198","author":"Kurmi","year":"2021","journal-title":"J. Pharm. Biomed. Anal."},{"key":"D4AY02050B\/cit25\/1","doi-asserted-by":"publisher","first-page":"115868","DOI":"10.1016\/j.jpba.2023.115868","volume":"238","author":"Shi","year":"2024","journal-title":"J. Pharm. Biomed. Anal."},{"key":"D4AY02050B\/cit26\/1","doi-asserted-by":"publisher","first-page":"124460","DOI":"10.1016\/j.jchromb.2025.124460","volume":"1252","author":"Guo","year":"2025","journal-title":"J. Chromatogr., B: Anal. Technol. Biomed. Life Sci."},{"key":"D4AY02050B\/cit27\/1","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.jchromb.2013.02.021","volume":"926","author":"Vijaya Bhaskar","year":"2013","journal-title":"J. Chromatogr., B: Anal. Technol. Biomed. Life Sci."},{"key":"D4AY02050B\/cit28\/1","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.4155\/bio-2020-0097","volume":"12","author":"Liu","year":"2020","journal-title":"Bioanalysis"},{"key":"D4AY02050B\/cit29\/1","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/j.jconrel.2024.01.016","volume":"366","author":"Hyldbakk","year":"2024","journal-title":"J. Controlled Release"},{"key":"D4AY02050B\/cit30\/1","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.jpba.2018.12.030","volume":"165","author":"Kaza","year":"2019","journal-title":"J. Pharm. Biomed. Anal."},{"key":"D4AY02050B\/cit31\/1","doi-asserted-by":"publisher","first-page":"5193","DOI":"10.1021\/acs.analchem.6b04058","volume":"89","author":"Zhou","year":"2017","journal-title":"Anal. Chem."},{"key":"D4AY02050B\/cit32\/1","doi-asserted-by":"publisher","first-page":"2362","DOI":"10.1002\/jps.23506","volume":"102","author":"Longley","year":"2013","journal-title":"J. Pharm. Sci."},{"key":"D4AY02050B\/cit33\/1","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1023\/a:1018943613122","volume":"10","author":"Davies","year":"1993","journal-title":"Pharm. Res."}],"container-title":["Analytical Methods"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/AY\/D4AY02050B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:31:01Z","timestamp":1782927061000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ay\/article\/17\/13\/2676-2685\/837541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":33,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2025,3,27]]}},"URL":"https:\/\/doi.org\/10.1039\/d4ay02050b","relation":{},"ISSN":["1759-9660","1759-9679"],"issn-type":[{"value":"1759-9660","type":"print"},{"value":"1759-9679","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}