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Commun."],"abstract":"<jats:p>\n                    We herein report a novel synthetic route for chiral\n                    <jats:italic>cis<\/jats:italic>\n                    -vicinal halohydrins derivatives through Ir\/f-phamidol-catalysed asymmetric hydrogenation of corresponding \u03b1-halogenated ketones with up to 99% yield, up to &gt;99% dr, and up to 99% ee.\n                  <\/jats:p>","DOI":"10.1039\/d4cc02529f","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T03:40:35Z","timestamp":1722829235000},"page":"9785-9788","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Highly efficient synthesis of enantioenriched vicinal halohydrins\n                    <i>via<\/i>\n                    Ir-catalyzed asymmetric hydrogenation using dynamic kinetic resolution"],"prefix":"10.1039","volume":"60","author":[{"given":"Bin","family":"He","sequence":"first","affiliation":[{"name":"Institute of Zhejiang University-Quzhou, Quzhou, 324000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2276-6800","authenticated-orcid":false,"given":"Gen-Qiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Academy for Advanced Interdisciplinary Studies and Guangdong Provincial Key Laboratory of Catalysis, Southern University of Science and Technology, Shenzhen 518055, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5700-0608","authenticated-orcid":false,"given":"Xumu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Medi-X Pingshan and Department of Chemistry, Southern University of Science and Technology, Shenzhen 518000, People's Republic of China"},{"name":"Chemistry and Chemical Engineering Guangdong Laboratory, Shantou 515031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D4CC02529F\/cit1\/1","doi-asserted-by":"crossref","first-page":"3081","DOI":"10.1021\/jm00094a025","volume":"35","author":"Bloom","year":"1992","journal-title":"J. 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