{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T20:44:52Z","timestamp":1788295492765,"version":"build-2803163510"},"reference-count":55,"publisher":"Royal Society of Chemistry (RSC)","issue":"13","license":[{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"am","delay-in-days":512,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100019081","name":"Science and Technology Program of Hunan Province","doi-asserted-by":"publisher","award":["2021NK1020"],"award-info":[{"award-number":["2021NK1020"]}],"id":[{"id":"10.13039\/501100019081","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFD1600805"],"award-info":[{"award-number":["2022YFD1600805"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>Study of the protective effects of LTA and DHM on the reproductive function of male mice under HS conditions and the underlying mechanisms, to provide scientific evidence for these substances to be used as functional food ingredients against HS.<\/jats:p>","DOI":"10.1039\/d4fo00208c","type":"journal-article","created":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T11:00:56Z","timestamp":1716807656000},"page":"7093-7107","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Protective effects of\n                    <scp>l<\/scp>\n                    -theanine and dihydromyricetin on reproductive function in male mice under heat stress"],"prefix":"10.1039","volume":"15","author":[{"given":"Difei","family":"Yang","sequence":"first","affiliation":[{"name":"Key Laboratory of Tea Science, Ministry of Education, Hunan Agricultural University, Changsha 410128, China"},{"name":"National Engineering Research Center of Functional Plant Components Utilization, Hunan Agricultural University, Changsha 410128, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaihang","family":"Xu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tea Science, Ministry of Education, Hunan Agricultural University, Changsha 410128, China"},{"name":"National Engineering Research Center of Functional Plant Components Utilization, Hunan Agricultural University, Changsha 410128, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenmao","family":"Wang","sequence":"additional","affiliation":[{"name":"Zhangjiajie Qiankun Berry Tea Engineering Technology Research Center, Zhangjiajie 427000, China"},{"name":"Hunan Qiankun Biotechnology Co., Ltd., Zhangjiajie 427000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peijian","family":"Chen","sequence":"additional","affiliation":[{"name":"Zhangjiajie Qiankun Berry Tea Engineering Technology Research Center, Zhangjiajie 427000, China"},{"name":"Hunan Qiankun Biotechnology Co., Ltd., Zhangjiajie 427000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Liu","sequence":"additional","affiliation":[{"name":"Zhangjiajie Qiankun Berry Tea Engineering Technology Research Center, Zhangjiajie 427000, China"},{"name":"Hunan Qiankun Biotechnology Co., Ltd., Zhangjiajie 427000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sha","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tea Science, Ministry of Education, Hunan Agricultural University, Changsha 410128, China"},{"name":"National Engineering Research Center of Functional Plant Components Utilization, Hunan Agricultural University, Changsha 410128, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8264-8561","authenticated-orcid":false,"given":"Wei","family":"Xu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tea Science, Ministry of Education, Hunan Agricultural University, Changsha 410128, China"},{"name":"National Engineering Research Center of Functional Plant Components Utilization, Hunan Agricultural University, Changsha 410128, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6258-4414","authenticated-orcid":false,"given":"Wenjun","family":"Xiao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tea Science, Ministry of Education, Hunan Agricultural University, Changsha 410128, China"},{"name":"National Engineering Research Center of Functional Plant Components Utilization, Hunan Agricultural University, Changsha 410128, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"issue":"37","key":"D4FO00208C\/cit1\/1","doi-asserted-by":"publisher","first-page":"603","DOI":"10.3238\/arztebl.2020.0603","volume":"117","author":"An der Heiden","year":"2020","journal-title":"Dtsch. Arztebl. Int."},{"issue":"1","key":"D4FO00208C\/cit2\/1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.aju.2017.12.004","volume":"16","author":"Durairajanayagam","year":"2018","journal-title":"Arab J. Urol."},{"issue":"3","key":"D4FO00208C\/cit3\/1","doi-asserted-by":"publisher","first-page":"388","DOI":"10.2486\/indhealth.44.388","volume":"44","author":"Epstein","year":"2006","journal-title":"Ind. Health"},{"issue":"1","key":"D4FO00208C\/cit4\/1","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.rbmo.2014.09.018","volume":"30","author":"Durairajanayagam","year":"2015","journal-title":"Reprod. BioMed. Online"},{"issue":"2","key":"D4FO00208C\/cit5\/1","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.shaw.2017.07.003","volume":"9","author":"Hamerezaee","year":"2018","journal-title":"Saf. Health Work"},{"key":"D4FO00208C\/cit6\/1","doi-asserted-by":"publisher","first-page":"110639","DOI":"10.1016\/j.mce.2019.110639","volume":"500","author":"Li","year":"2020","journal-title":"Mol. Cell. Endocrinol."},{"issue":"5","key":"D4FO00208C\/cit7\/1","doi-asserted-by":"publisher","first-page":"1012","DOI":"10.1093\/humrep\/16.5.1012","volume":"16","author":"J\u00f8rgensen","year":"2001","journal-title":"Hum. Reprod."},{"key":"D4FO00208C\/cit8\/1","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1016\/j.envpol.2018.01.021","volume":"235","author":"Santi","year":"2018","journal-title":"Environ. Pollut."},{"issue":"15","key":"D4FO00208C\/cit9\/1","doi-asserted-by":"publisher","first-page":"2623","DOI":"10.1007\/s00018-012-1165-4","volume":"70","author":"Kim","year":"2013","journal-title":"Cell. Mol. Life Sci."},{"issue":"2","key":"D4FO00208C\/cit10\/1","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1093\/humrep\/13.2.372","volume":"13","author":"Jannes","year":"1998","journal-title":"Hum. Reprod."},{"issue":"10","key":"D4FO00208C\/cit11\/1","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1071\/rd19303","volume":"32","author":"Jia","year":"2020","journal-title":"Reprod., Fertil. Dev."},{"issue":"1","key":"D4FO00208C\/cit12\/1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1177\/0960327120940366","volume":"40","author":"Delkhosh","year":"2021","journal-title":"Hum. Exp. Toxicol."},{"key":"D4FO00208C\/cit13\/1","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1146\/annurev-biochem-060809-095203","volume":"80","author":"Anckar","year":"2011","journal-title":"Annu. Rev. Biochem."},{"issue":"5","key":"D4FO00208C\/cit14\/1","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.1091\/mbc.e08-08-0864","volume":"20","author":"Sandqvist","year":"2009","journal-title":"Mol. Biol. Cell"},{"issue":"10","key":"D4FO00208C\/cit15\/1","doi-asserted-by":"publisher","first-page":"5285","DOI":"10.1128\/mcb.11.10.5285\u20135290.1991","volume":"11","author":"O'Brien","year":"1991","journal-title":"Mol. Cell. Biol."},{"key":"D4FO00208C\/cit16\/1","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.theriogenology.2020.08.034","volume":"158","author":"Shahat","year":"2020","journal-title":"Theriogenology"},{"issue":"10","key":"D4FO00208C\/cit17\/1","doi-asserted-by":"publisher","first-page":"5463","DOI":"10.1039\/c8fo01207e","volume":"9","author":"Kumar","year":"2018","journal-title":"Food Funct."},{"issue":"5","key":"D4FO00208C\/cit18\/1","doi-asserted-by":"publisher","first-page":"3065","DOI":"10.1074\/jbc.C100685200","volume":"277","author":"Neininger","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"8","key":"D4FO00208C\/cit19\/1","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.1016\/j.bmcl.2017.02.045","volume":"27","author":"Cai","year":"2017","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D4FO00208C\/cit20\/1","doi-asserted-by":"publisher","first-page":"125495","DOI":"10.1016\/j.chemosphere.2019.125495","volume":"244","author":"Song","year":"2020","journal-title":"Chemosphere"},{"issue":"2","key":"D4FO00208C\/cit21\/1","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s12012-008-9016-0","volume":"8","author":"Zhu","year":"2008","journal-title":"Cardiovasc. Toxicol."},{"issue":"6549","key":"D4FO00208C\/cit22\/1","doi-asserted-by":"publisher","first-page":"eabc3593","DOI":"10.1126\/science.abc3593","volume":"372","author":"Maxwell","year":"2021","journal-title":"Science"},{"issue":"7\u20138","key":"D4FO00208C\/cit23\/1","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/s10495-021-01678-w","volume":"26","author":"Verma","year":"2021","journal-title":"Apoptosis"},{"issue":"12","key":"D4FO00208C\/cit24\/1","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1038\/ncpuro0650","volume":"3","author":"Srinivas-Shankar","year":"2006","journal-title":"Nat. Clin. Pract. Urol."},{"issue":"4","key":"D4FO00208C\/cit25\/1","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1097\/mop.0000000000000928","volume":"32","author":"Witchel","year":"2020","journal-title":"Curr. Opin. Pediatr."},{"key":"D4FO00208C\/cit26\/1","doi-asserted-by":"publisher","first-page":"e005","DOI":"10.1621\/nrs.05005","volume":"5","author":"Weigel","year":"2007","journal-title":"Nucl. Recept. Signaling"},{"key":"D4FO00208C\/cit27\/1","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.1071\/rd14370","volume":"28","author":"Li","year":"2016","journal-title":"Reprod., Fertil. Dev."},{"issue":"7","key":"D4FO00208C\/cit28\/1","doi-asserted-by":"publisher","first-page":"2722","DOI":"10.1210\/endo.138.7.5278","volume":"138","author":"Liu","year":"1997","journal-title":"Endocrinology"},{"key":"D4FO00208C\/cit29\/1","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1210\/mend.15.8.0676","volume":"15(8)","author":"Murphy","year":"2001","journal-title":"Mol. Endocrinol."},{"issue":"8","key":"D4FO00208C\/cit30\/1","doi-asserted-by":"publisher","first-page":"2648","DOI":"10.1210\/en.2017-00132","volume":"158","author":"Oka","year":"2017","journal-title":"Endocrinology"},{"key":"D4FO00208C\/cit31\/1","doi-asserted-by":"crossref","first-page":"3487","DOI":"10.3390\/cancers14143487","volume":"14","author":"Wu","year":"2022","journal-title":"Cancers"},{"key":"D4FO00208C\/cit32\/1","doi-asserted-by":"crossref","first-page":"112610","DOI":"10.1016\/j.biopha.2021.112610","volume":"146","author":"Kabir","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"D4FO00208C\/cit33\/1","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3390\/biom11030392","volume":"11","author":"Kabir","year":"2021","journal-title":"Biomolecules"},{"key":"D4FO00208C\/cit34\/1","doi-asserted-by":"crossref","first-page":"1381428","DOI":"10.3389\/fvets.2024.1381428","volume":"11","author":"Alanazi","year":"2024","journal-title":"Front. Vet. Sci."},{"issue":"8","key":"D4FO00208C\/cit35\/1","doi-asserted-by":"publisher","first-page":"1681","DOI":"10.1080\/10408398.2015.1016141","volume":"57","author":"T\u00fcrk\u00f6z\u00fc","year":"2017","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"D4FO00208C\/cit36\/1","doi-asserted-by":"publisher","first-page":"1053617","DOI":"10.1155\/2017\/1053617","volume":"2017","author":"Li","year":"2017","journal-title":"J. Evidence-Based Complementary Altern. Med."},{"issue":"4","key":"D4FO00208C\/cit37\/1","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1039\/d1fo03077a","volume":"13","author":"Liu","year":"2022","journal-title":"Food Funct."},{"issue":"1","key":"D4FO00208C\/cit38\/1","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1039\/d2fo02775e","volume":"14","author":"Hu","year":"2023","journal-title":"Food Funct."},{"issue":"8","key":"D4FO00208C\/cit39\/1","doi-asserted-by":"publisher","first-page":"1661","DOI":"10.1007\/s11064-015-1648-4","volume":"40","author":"Ben","year":"2015","journal-title":"Neurochem. Res."},{"key":"D4FO00208C\/cit40\/1","doi-asserted-by":"publisher","first-page":"112078","DOI":"10.1016\/j.ecoenv.2021.112078","volume":"214","author":"Wang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"D4FO00208C\/cit41\/1","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.jff.2019.01.011","volume":"54","author":"Gong","year":"2019","journal-title":"J. Funct. Foods"},{"issue":"6","key":"D4FO00208C\/cit42\/1","doi-asserted-by":"publisher","first-page":"BSR20210443","DOI":"10.1042\/bsr20210443","volume":"41","author":"Cai","year":"2021","journal-title":"Biosci. Rep."},{"key":"D4FO00208C\/cit43\/1","doi-asserted-by":"publisher","first-page":"834","DOI":"10.3390\/nu10070834","volume":"10","author":"Rahman","year":"2018","journal-title":"Nutrients"},{"key":"D4FO00208C\/cit44\/1","doi-asserted-by":"crossref","first-page":"8050","DOI":"10.1021\/acs.jafc.3c01010","volume":"71","author":"Ye","year":"2023","journal-title":"J. Agric. Food Chem."},{"issue":"1","key":"D4FO00208C\/cit45\/1","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1002\/mrd.20759","volume":"75","author":"P\u00e9rez-Crespo","year":"2008","journal-title":"Mol. Reprod. Dev."},{"issue":"4","key":"D4FO00208C\/cit46\/1","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/j.jgr.2016.12.001","volume":"41","author":"Kopalli","year":"2017","journal-title":"J. Ginseng Res"},{"issue":"Suppl 1)","key":"D4FO00208C\/cit47\/1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/s1472-6483(11)60210-1","volume":"5","author":"Ortmann","year":"2002","journal-title":"Reprod. BioMed. Online"},{"issue":"4","key":"D4FO00208C\/cit48\/1","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.3390\/jcm9041014","volume":"9","author":"Santi","year":"2020","journal-title":"J. Clin. Med."},{"issue":"2","key":"D4FO00208C\/cit49\/1","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1093\/molehr\/gaaa002","volume":"26","author":"Zhang","year":"2020","journal-title":"Mol. Hum. Reprod."},{"key":"D4FO00208C\/cit50\/1","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.3389\/fphar.2018.01204","volume":"9","author":"Zhang","year":"2018","journal-title":"Front. Pharmacol."},{"issue":"4","key":"D4FO00208C\/cit51\/1","doi-asserted-by":"publisher","first-page":"16616","DOI":"10.4238\/2015.December.11.9","volume":"14","author":"Cao","year":"2015","journal-title":"Genet. Mol. Res."},{"issue":"1","key":"D4FO00208C\/cit52\/1","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1054\/clnu.1999.0073","volume":"19","author":"Reimund","year":"2000","journal-title":"Clin. Nutr."},{"issue":"4","key":"D4FO00208C\/cit53\/1","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.3892\/ijmm.2016.2503","volume":"37","author":"Ding","year":"2016","journal-title":"Int. J. Mol. Med."},{"issue":"3","key":"D4FO00208C\/cit54\/1","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.tibs.2021.10.004","volume":"47","author":"Kmiecik","year":"2022","journal-title":"Trends Biochem. Sci."},{"issue":"10","key":"D4FO00208C\/cit55\/1","doi-asserted-by":"publisher","first-page":"36","DOI":"10.13982\/j.mfst.1673-9078.2014.10.007","volume":"30","author":"Cao","year":"2014","journal-title":"Mod. Food Sci. Technol."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/FO\/D4FO00208C","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T18:18:41Z","timestamp":1783275521000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/15\/13\/7093-7107\/850771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":55,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2024,7,1]]}},"URL":"https:\/\/doi.org\/10.1039\/d4fo00208c","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}