{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T14:51:04Z","timestamp":1790952664004,"version":"4.1.0"},"reference-count":54,"publisher":"Royal Society of Chemistry (RSC)","issue":"8","license":[{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"am","delay-in-days":447,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"publisher","award":["2022YFF1100102"],"award-info":[{"award-number":["2022YFF1100102"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"publisher","award":["2022YFC2105005"],"award-info":[{"award-number":["2022YFC2105005"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32172749"],"award-info":[{"award-number":["32172749"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31625025"],"award-info":[{"award-number":["31625025"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>Over the past two decades, the occurrence of hyperuricemia and its influence on health have drawn lots of concern all over the world.<\/jats:p>","DOI":"10.1039\/d4fo00731j","type":"journal-article","created":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T18:02:58Z","timestamp":1742839378000},"page":"2991-3003","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Hydrolysate of goat milk casein supplementation alleviates hyperuricemia and modulates gut microbiota in C57BL6\/J mice"],"prefix":"10.1039","volume":"16","author":[{"given":"Mingrui","family":"Yang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Animal Nutrition and Feeding, Department of Companion Animal Science, China Agricultural University, Beijing, 100193, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1840-7138","authenticated-orcid":false,"given":"Yiqing","family":"Zhao","sequence":"additional","affiliation":[{"name":"Ausnutria Hyproca Nutrition Co. Ltd., Changsha, Hunan Province, 410011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoling","family":"Zeng","sequence":"additional","affiliation":[{"name":"Ausnutria Dairy (China) Co., Ltd., Changsha 410219, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiling","family":"Deng","sequence":"additional","affiliation":[{"name":"Ausnutria Hyproca Nutrition Co. Ltd., Changsha, Hunan Province, 410011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Pan","sequence":"additional","affiliation":[{"name":"Ausnutria Dairy (China) Co., Ltd., Changsha 410219, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Wang","sequence":"additional","affiliation":[{"name":"Ausnutria Dairy (China) Co., Ltd., Changsha 410219, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[{"name":"Ausnutria Dairy (China) Co., Ltd., Changsha 410219, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanmei","family":"Hou","sequence":"additional","affiliation":[{"name":"Ausnutria Hyproca Nutrition Co. Ltd., Changsha, Hunan Province, 410011, China"},{"name":"Ausnutria Dairy (China) Co., Ltd., Changsha 410219, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Animal Nutrition and Feeding, Department of Companion Animal Science, China Agricultural University, Beijing, 100193, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9348-5761","authenticated-orcid":false,"given":"Zhenlong","family":"Wu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Animal Nutrition and Feeding, Department of Companion Animal Science, China Agricultural University, Beijing, 100193, P. R. China"},{"name":"Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, 100193, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"issue":"4","key":"D4FO00731J\/cit1\/1","first-page":"760","volume":"29","author":"\u00c1lvarez-Lario","year":"2014","journal-title":"Nutr. Hosp."},{"issue":"5","key":"D4FO00731J\/cit2\/1","first-page":"679","volume":"56","author":"Ben Salem","year":"2017","journal-title":"Rheumatology"},{"issue":"7","key":"D4FO00731J\/cit3\/1","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1002\/art.24612","volume":"61","author":"Kim","year":"2009","journal-title":"Arthritis Rheum."},{"issue":"6","key":"D4FO00731J\/cit4\/1","doi-asserted-by":"crossref","first-page":"3188","DOI":"10.3390\/ijms23063188","volume":"23","author":"Gherghina","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"D4FO00731J\/cit5\/1","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1097\/00007890-200104150-00014","volume":"71","author":"Mazzali","year":"2001","journal-title":"Transplantation"},{"issue":"1","key":"D4FO00731J\/cit6\/1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jjcc.2020.12.013","volume":"78","author":"Saito","year":"2021","journal-title":"J. Cardiol."},{"issue":"12","key":"D4FO00731J\/cit7\/1","first-page":"1426","volume":"94","author":"Mironova","year":"2023","journal-title":"Ter. Arkh."},{"issue":"1","key":"D4FO00731J\/cit8\/1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/s41572-019-0115-y","volume":"5","author":"Dalbeth","year":"2019","journal-title":"Nat. Rev. Dis. Primers"},{"issue":"8","key":"D4FO00731J\/cit9\/1","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.molmed.2017.06.005","volume":"23","author":"Desai","year":"2017","journal-title":"Trends Mol. Med."},{"issue":"2","key":"D4FO00731J\/cit10\/1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1007\/s11926-011-0162-1","volume":"13","author":"Ghaemi-Oskouie","year":"2011","journal-title":"Curr. Rheumatol. Rep."},{"key":"D4FO00731J\/cit11\/1","doi-asserted-by":"crossref","first-page":"110990","DOI":"10.1016\/j.biopha.2020.110990","volume":"133","author":"Shen","year":"2021","journal-title":"Biomed. Pharmacother."},{"issue":"6","key":"D4FO00731J\/cit12\/1","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.3390\/ijms21062147","volume":"21","author":"Hong","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"D4FO00731J\/cit13\/1","doi-asserted-by":"crossref","first-page":"889464","DOI":"10.3389\/fmed.2022.889464","volume":"9","author":"Huang","year":"2022","journal-title":"Front. Med."},{"issue":"3","key":"D4FO00731J\/cit14\/1","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1053\/j.ajkd.2017.01.055","volume":"70","author":"Vargas-Santos","year":"2017","journal-title":"Am. J. Kidney Dis."},{"issue":"13","key":"D4FO00731J\/cit15\/1","doi-asserted-by":"crossref","first-page":"E483","DOI":"10.1503\/cmaj.221575","volume":"195","author":"Yaseen","year":"2023","journal-title":"Can. Med. Assoc. J."},{"issue":"6","key":"D4FO00731J\/cit16\/1","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.jbspin.2004.07.006","volume":"71","author":"Bardin","year":"2004","journal-title":"Jt., Bone, Spine"},{"issue":"7","key":"D4FO00731J\/cit17\/1","doi-asserted-by":"crossref","first-page":"e202304191","DOI":"10.1002\/slct.202304191","volume":"9","author":"Ningsih","year":"2024","journal-title":"ChemistrySelect"},{"issue":"4","key":"D4FO00731J\/cit18\/1","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1111\/ijfs.14789","volume":"56","author":"Qin","year":"2021","journal-title":"Int. J. Food Sci. Technol."},{"key":"D4FO00731J\/cit19\/1","first-page":"012043","volume":"1374","author":"Mulyati","year":"2019","journal-title":"J. Phys.: Conf. Ser."},{"key":"D4FO00731J\/cit20\/1","doi-asserted-by":"crossref","first-page":"878768","DOI":"10.3389\/fnut.2022.878768","volume":"9","author":"Qiao","year":"2022","journal-title":"Front. Nutr."},{"key":"D4FO00731J\/cit21\/1","doi-asserted-by":"crossref","first-page":"111310","DOI":"10.1016\/j.foodres.2022.111310","volume":"157","author":"Magalh\u00e3es","year":"2022","journal-title":"Food Res. Int."},{"issue":"9","key":"D4FO00731J\/cit22\/1","doi-asserted-by":"crossref","first-page":"e20328","DOI":"10.1016\/j.heliyon.2023.e20328","volume":"9","author":"Liu","year":"2023","journal-title":"Heliyon"},{"issue":"14","key":"D4FO00731J\/cit23\/1","doi-asserted-by":"crossref","first-page":"e2100147","DOI":"10.1002\/mnfr.202100147","volume":"65","author":"Lu","year":"2021","journal-title":"Mol. Nutr. Food Res."},{"issue":"7","key":"D4FO00731J\/cit24\/1","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.3390\/nu16071086","volume":"16","author":"Zhou","year":"2024","journal-title":"Nutrients"},{"key":"D4FO00731J\/cit25\/1","doi-asserted-by":"crossref","first-page":"174592","DOI":"10.1016\/j.ejphar.2021.174592","volume":"912","author":"Lin","year":"2021","journal-title":"Eur. J. Pharmacol."},{"key":"D4FO00731J\/cit26\/1","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/s13071-016-1435-3","volume":"9","author":"Liu","year":"2016","journal-title":"Parasites Vectors"},{"issue":"17","key":"D4FO00731J\/cit27\/1","doi-asserted-by":"crossref","first-page":"i884","DOI":"10.1093\/bioinformatics\/bty560","volume":"34","author":"Chen","year":"2018","journal-title":"Bioinformatics"},{"issue":"21","key":"D4FO00731J\/cit28\/1","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1093\/bioinformatics\/btr507","volume":"27","author":"Mago\u010d","year":"2011","journal-title":"Bioinformatics"},{"issue":"1","key":"D4FO00731J\/cit29\/1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s10620-021-06848-z","volume":"67","author":"Wada","year":"2022","journal-title":"Dig. Dis. Sci."},{"issue":"1","key":"D4FO00731J\/cit30\/1","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1096\/fasebj.7.1.8422969","volume":"7","author":"Stackebrandt","year":"1993","journal-title":"FASEB J."},{"key":"D4FO00731J\/cit31\/1","doi-asserted-by":"crossref","first-page":"e3889","DOI":"10.7717\/peerj.3889","volume":"5","author":"Edgar","year":"2017","journal-title":"PeerJ"},{"issue":"16","key":"D4FO00731J\/cit32\/1","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1128\/AEM.00062-07","volume":"73","author":"Wang","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"issue":"6","key":"D4FO00731J\/cit33\/1","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/s41587-020-0548-6","volume":"38","author":"Douglas","year":"2020","journal-title":"Nat. Biotechnol."},{"issue":"2","key":"D4FO00731J\/cit34\/1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/BOR.0000000000000779","volume":"33","author":"Yokose","year":"2021","journal-title":"Curr. Opin. Rheumatol."},{"issue":"9","key":"D4FO00731J\/cit35\/1","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1002\/jsfa.11708","volume":"102","author":"Liu","year":"2022","journal-title":"J. Sci. Food Agric."},{"issue":"10","key":"D4FO00731J\/cit36\/1","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1007\/s00726-022-03152-6","volume":"55","author":"Parastouei","year":"2023","journal-title":"Amino Acids"},{"issue":"6","key":"D4FO00731J\/cit37\/1","doi-asserted-by":"crossref","first-page":"4907","DOI":"10.3168\/jds.2019-17513","volume":"103","author":"Gong","year":"2020","journal-title":"J. Dairy Sci."},{"issue":"4","key":"D4FO00731J\/cit38\/1","doi-asserted-by":"crossref","first-page":"5061","DOI":"10.1096\/fj.201902597RR","volume":"34","author":"Han","year":"2020","journal-title":"FASEB J."},{"issue":"1","key":"D4FO00731J\/cit39\/1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1080\/07435800.2020.1850760","volume":"46","author":"Feng","year":"2021","journal-title":"Endocr. Res."},{"issue":"17","key":"D4FO00731J\/cit40\/1","doi-asserted-by":"crossref","first-page":"9221","DOI":"10.3390\/ijms22179221","volume":"22","author":"Yanai","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"D4FO00731J\/cit41\/1","first-page":"F1327","volume":"318","author":"Jung","year":"2020","journal-title":"Am. J. Physiol.: Renal Physiol."},{"issue":"4","key":"D4FO00731J\/cit42\/1","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.jhep.2015.11.022","volume":"64","author":"Wan","year":"2016","journal-title":"J. Hepatol."},{"issue":"14","key":"D4FO00731J\/cit43\/1","doi-asserted-by":"crossref","first-page":"3979","DOI":"10.1080\/10408398.2021.1874287","volume":"62","author":"Wang","year":"2022","journal-title":"Crit. Rev. Food Sci. Nutr."},{"issue":"14","key":"D4FO00731J\/cit44\/1","doi-asserted-by":"crossref","first-page":"3979","DOI":"10.1080\/10408398.2021.1874287","volume":"62","author":"Wang","year":"2021","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"D4FO00731J\/cit45\/1","doi-asserted-by":"crossref","first-page":"fnad016","DOI":"10.1093\/femsle\/fnad016","volume":"370","author":"Yin","year":"2023","journal-title":"FEMS Microbiol. Lett."},{"issue":"3","key":"D4FO00731J\/cit46\/1","doi-asserted-by":"crossref","first-page":"586","DOI":"10.3390\/nu15030586","volume":"15","author":"Jiang","year":"2023","journal-title":"Nutrients"},{"key":"D4FO00731J\/cit47\/1","doi-asserted-by":"crossref","first-page":"940228","DOI":"10.3389\/fimmu.2022.940228","volume":"13","author":"Cao","year":"2022","journal-title":"Front. Immunol."},{"key":"D4FO00731J\/cit48\/1","doi-asserted-by":"crossref","first-page":"934695","DOI":"10.3389\/fimmu.2022.934695","volume":"13","author":"Rodrigues","year":"2022","journal-title":"Front. Immunol."},{"issue":"22","key":"D4FO00731J\/cit49\/1","doi-asserted-by":"crossref","first-page":"9066","DOI":"10.1073\/pnas.1219451110","volume":"110","author":"Everard","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"D4FO00731J\/cit50\/1","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1038\/s41467-023-37533-6","volume":"14","author":"Shuoker","year":"2023","journal-title":"Nat. Commun."},{"issue":"17","key":"D4FO00731J\/cit51\/1","doi-asserted-by":"crossref","first-page":"6356","DOI":"10.3390\/ijms21176356","volume":"21","author":"He","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"D4FO00731J\/cit52\/1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jaut.2018.05.008","volume":"92","author":"Rizzetto","year":"2018","journal-title":"J. Autoimmun."},{"key":"D4FO00731J\/cit53\/1","doi-asserted-by":"crossref","first-page":"101744","DOI":"10.1016\/j.arr.2022.101744","volume":"82","author":"Rashidah","year":"2022","journal-title":"Ageing Res. Rev."},{"issue":"4","key":"D4FO00731J\/cit54\/1","first-page":"G484","volume":"317","author":"Xu","year":"2019","journal-title":"Am. J. Physiol.: Gastrointest. Liver Physiol."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/FO\/D4FO00731J","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T18:19:18Z","timestamp":1783448358000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/16\/8\/2991-3003\/850851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":54,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,4,14]]}},"URL":"https:\/\/doi.org\/10.1039\/d4fo00731j","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}