{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T19:36:04Z","timestamp":1783452964247,"version":"3.55.0"},"reference-count":49,"publisher":"Royal Society of Chemistry (RSC)","issue":"20","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"am","delay-in-days":638,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32172211"],"award-info":[{"award-number":["32172211"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFF1103300"],"award-info":[{"award-number":["2022YFF1103300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>ISO exhibited a remarkable anti-motion sickness effect by regulating glutamatergic synapses and the downstream NMDAR1\/CaMKII\/CREB signaling pathway!.<\/jats:p>","DOI":"10.1039\/d4fo02761b","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T06:16:55Z","timestamp":1727677015000},"page":"10300-10315","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Deep insights into the mechanism of isorhamnetin's anti-motion sickness effect based on photoshoproteomics"],"prefix":"10.1039","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6037-4360","authenticated-orcid":false,"given":"Li","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China"},{"name":"Food Laboratory of Zhongyuan, Zhengzhou University, Luohe, 462300, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyan","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China"},{"name":"Food Laboratory of Zhongyuan, Zhengzhou University, Luohe, 462300, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoran","family":"Kong","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China"},{"name":"Food Laboratory of Zhongyuan, Zhengzhou University, Luohe, 462300, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China"},{"name":"Food Laboratory of Zhongyuan, Zhengzhou University, Luohe, 462300, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Limin","family":"Hao","sequence":"additional","affiliation":[{"name":"Systems Engineering Institute, Academy of Military Sciences (AMS), Beijing, 100010, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanling","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqing","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China"},{"name":"Food Laboratory of Zhongyuan, Zhengzhou University, Luohe, 462300, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9339-4835","authenticated-orcid":false,"given":"Jike","family":"Lu","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China"},{"name":"Food Laboratory of Zhongyuan, Zhengzhou University, Luohe, 462300, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D4FO02761B\/cit1\/1","first-page":"687","volume":"115","author":"Koch","year":"2018","journal-title":"Dtsch. Arztebl. Int."},{"key":"D4FO02761B\/cit2\/1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3389\/fneur.2016.00014","volume":"7","author":"Bertolini","year":"2016","journal-title":"Front. Neurol."},{"key":"D4FO02761B\/cit3\/1","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1007\/s00405-009-0927-6","volume":"266","author":"Buyuklu","year":"2009","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"D4FO02761B\/cit4\/1","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1007\/s00221-014-3937-6","volume":"232","author":"Yates","year":"2014","journal-title":"Exp. Brain Res."},{"key":"D4FO02761B\/cit5\/1","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1002\/ptr.3316","volume":"25","author":"Heimes","year":"2011","journal-title":"Phytother. Res."},{"key":"D4FO02761B\/cit6\/1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s11064-019-02923-0","volume":"45","author":"Deshetty","year":"2020","journal-title":"Neurochem. Res."},{"key":"D4FO02761B\/cit7\/1","doi-asserted-by":"crossref","first-page":"230","DOI":"10.14429\/dlsj.5.14822","volume":"5","author":"Kumar","year":"2020","journal-title":"Def. Life Sci. J."},{"key":"D4FO02761B\/cit8\/1","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.brainres.2019.02.017","volume":"1712","author":"Ishola","year":"2019","journal-title":"Brain Res."},{"key":"D4FO02761B\/cit9\/1","doi-asserted-by":"crossref","first-page":"110301","DOI":"10.1016\/j.biopha.2020.110301","volume":"128","author":"Gong","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"D4FO02761B\/cit10\/1","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1007\/s11064-016-1904-2","volume":"41","author":"Zhao","year":"2016","journal-title":"Neurochem. Res."},{"key":"D4FO02761B\/cit11\/1","doi-asserted-by":"crossref","first-page":"105816","DOI":"10.1016\/j.fitote.2023.105816","volume":"173","author":"Zhao","year":"2024","journal-title":"Fitoterapia"},{"key":"D4FO02761B\/cit12\/1","doi-asserted-by":"crossref","first-page":"115077","DOI":"10.1016\/j.jep.2022.115077","volume":"290","author":"Zhong","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"D4FO02761B\/cit13\/1","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1111\/j.1755-5949.2011.00272.x","volume":"17","author":"Wei","year":"2011","journal-title":"CNS Neurosci. Ther."},{"key":"D4FO02761B\/cit14\/1","first-page":"165","volume":"24","author":"Li","year":"2011","journal-title":"J. Psychiatry"},{"key":"D4FO02761B\/cit15\/1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s12868-021-00643-2","volume":"22","author":"Ringland","year":"2021","journal-title":"BMC Neurosci."},{"key":"D4FO02761B\/cit16\/1","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.schres.2011.11.002","volume":"135","author":"Adkins","year":"2012","journal-title":"Schizophr. Res."},{"key":"D4FO02761B\/cit17\/1","first-page":"527","volume":"285","author":"Viu","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"D4FO02761B\/cit18\/1","doi-asserted-by":"crossref","first-page":"114107","DOI":"10.1016\/j.jep.2021.114107","volume":"275","author":"Zhang","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"D4FO02761B\/cit19\/1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.molbiopara.2011.07.002","volume":"180","author":"Ressurrei\u00e7\u00e3o","year":"2011","journal-title":"Mol. Biochem. Parasitol."},{"key":"D4FO02761B\/cit20\/1","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1101\/gad.1903310","volume":"24","author":"Lian","year":"2010","journal-title":"Genes Dev."},{"key":"D4FO02761B\/cit21\/1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1677\/JOE-10-0064","volume":"206","author":"Bu","year":"2010","journal-title":"J. Endocrinol."},{"key":"D4FO02761B\/cit22\/1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/aps.2009.201","volume":"31","author":"Wang","year":"2010","journal-title":"Acta Pharmacol. Sin."},{"key":"D4FO02761B\/cit23\/1","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1186\/s12859-019-3170-1","volume":"20","author":"Li","year":"2019","journal-title":"BMC Bioinf."},{"key":"D4FO02761B\/cit24\/1","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1002\/pmic.201000579","volume":"11","author":"Cairns","year":"2011","journal-title":"Proteomics"},{"key":"D4FO02761B\/cit25\/1","doi-asserted-by":"crossref","first-page":"115024","DOI":"10.1016\/j.biopha.2023.115024","volume":"165","author":"Powis","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"D4FO02761B\/cit26\/1","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1039\/D2MO00061J","volume":"18","author":"Xu","year":"2022","journal-title":"Mol. Omics"},{"key":"D4FO02761B\/cit27\/1","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.pnpbp.2017.09.014","volume":"84","author":"Moretto","year":"2018","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"D4FO02761B\/cit28\/1","doi-asserted-by":"crossref","first-page":"108622","DOI":"10.1016\/j.neuropharm.2021.108622","volume":"193","author":"Feng","year":"2021","journal-title":"Neuropharmacology"},{"key":"D4FO02761B\/cit29\/1","doi-asserted-by":"crossref","first-page":"3008","DOI":"10.3390\/ijms19123800","volume":"19","author":"Montes de Oca Balderas","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"D4FO02761B\/cit30\/1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/nar\/27.1.29","volume":"27","author":"Ogata","year":"1999","journal-title":"Nucleic Acids Res."},{"key":"D4FO02761B\/cit31\/1","doi-asserted-by":"crossref","first-page":"11861","DOI":"10.1002\/jcp.27898","volume":"234","author":"Fiory","year":"2019","journal-title":"J. Cell. Physiol."},{"key":"D4FO02761B\/cit32\/1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s10072-015-2386-8","volume":"37","author":"Zeng","year":"2016","journal-title":"Neurol. Sci."},{"key":"D4FO02761B\/cit33\/1","doi-asserted-by":"crossref","first-page":"676","DOI":"10.3390\/antiox9080676","volume":"9","author":"Muraleva","year":"2020","journal-title":"Antioxidants"},{"key":"D4FO02761B\/cit34\/1","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1016\/j.bpj.2017.06.035","volume":"113","author":"Iacobucci","year":"2017","journal-title":"Biophys. J."},{"key":"D4FO02761B\/cit35\/1","doi-asserted-by":"crossref","first-page":"43385","DOI":"10.1038\/srep43385","volume":"7","author":"Wang","year":"2017","journal-title":"Sci. Rep."},{"key":"D4FO02761B\/cit36\/1","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1002\/glia.20724","volume":"56","author":"Nicchia","year":"2008","journal-title":"Glia"},{"key":"D4FO02761B\/cit37\/1","doi-asserted-by":"crossref","first-page":"e12723","DOI":"10.1111\/gbb.12723","volume":"20","author":"Horner","year":"2021","journal-title":"Genes, Brain Behav."},{"key":"D4FO02761B\/cit38\/1","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1038\/sj.onc.1201344","volume":"15","author":"Gallo","year":"1997","journal-title":"Oncogene"},{"key":"D4FO02761B\/cit39\/1","doi-asserted-by":"crossref","first-page":"e1000138","DOI":"10.1371\/journal.pbio.1000138","volume":"7","author":"Menna","year":"2009","journal-title":"PLoS Biol."},{"key":"D4FO02761B\/cit40\/1","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.ajhg.2008.10.008","volume":"83","author":"Bertram","year":"2008","journal-title":"Am. J. Hum. Genet."},{"key":"D4FO02761B\/cit41\/1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/hbm.23025","volume":"37","author":"Mathias","year":"2016","journal-title":"Hum. Brain Mapp."},{"key":"D4FO02761B\/cit42\/1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.neuropharm.2016.07.021","volume":"112","author":"Wang","year":"2017","journal-title":"Neuropharmacology"},{"key":"D4FO02761B\/cit43\/1","doi-asserted-by":"crossref","first-page":"313","DOI":"10.3389\/fnmol.2018.00313","volume":"11","author":"Morini","year":"2018","journal-title":"Front. Mol. Neurosci."},{"key":"D4FO02761B\/cit44\/1","first-page":"13","volume":"19","author":"Zhang","year":"2019","journal-title":"Prog. Mod. Biomed."},{"key":"D4FO02761B\/cit45\/1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3389\/fnsyn.2019.00006","volume":"11","author":"Chowdhury","year":"2019","journal-title":"Front. Synaptic Neurosci."},{"key":"D4FO02761B\/cit46\/1","first-page":"3715","volume":"42","author":"You","year":"2022","journal-title":"Chin. J. Gerontol."},{"key":"D4FO02761B\/cit47\/1","doi-asserted-by":"crossref","first-page":"113818","DOI":"10.1016\/j.bcp.2020.113818","volume":"176","author":"Zuccarello","year":"2020","journal-title":"Biochem. Pharmacol."},{"key":"D4FO02761B\/cit48\/1","first-page":"3073","volume":"24","author":"Imbrici","year":"2006","journal-title":"Eur. J. Neurol."},{"key":"D4FO02761B\/cit49\/1","doi-asserted-by":"crossref","first-page":"1207539","DOI":"10.3389\/fneur.2023.1207539","volume":"14","author":"Hou","year":"2023","journal-title":"Front. Neurol."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/FO\/D4FO02761B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T18:28:48Z","timestamp":1783448928000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/15\/20\/10300-10315\/851082"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":49,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2024,10,14]]}},"URL":"https:\/\/doi.org\/10.1039\/d4fo02761b","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}