{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:05:31Z","timestamp":1787004331331,"version":"build-2736575974"},"reference-count":38,"publisher":"Royal Society of Chemistry (RSC)","issue":"1","license":[{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"am","delay-in-days":324,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100018684","name":"National Health Commission of the People's Republic of China","doi-asserted-by":"publisher","award":["spaq-2019\u2013105"],"award-info":[{"award-number":["spaq-2019\u2013105"]}],"id":[{"id":"10.13039\/501100018684","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["818726101"],"award-info":[{"award-number":["818726101"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    The nutrition package improved the clinical symptoms (\n                    <jats:italic>e.g.<\/jats:italic>\n                    chest pain and expectoration) and the nutritional status of tuberculosis.\n                  <\/jats:p>","DOI":"10.1039\/d4fo05172f","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T04:21:53Z","timestamp":1732162913000},"page":"102-111","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Nutritional supplementation during tuberculosis treatment to improve clinical symptoms: a double-blinded placebo-controlled randomized trial"],"prefix":"10.1039","volume":"16","author":[{"given":"Yang","family":"Yang","sequence":"first","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Cai","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinfang","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixuan","family":"Lei","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenge","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Weifang Respiratory Disease Hospital, Weifang, Shandong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyu","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Weifang Respiratory Disease Hospital, Weifang, Shandong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Weifang Respiratory Disease Hospital, Weifang, Shandong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yidan","family":"Hu","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Weifang Respiratory Disease Hospital, Weifang, Shandong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Xu","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Guo","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanqiu","family":"Xu","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Xiong","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6831-1863","authenticated-orcid":false,"given":"Tianlin","family":"Gao","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Ma","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5577-4976","authenticated-orcid":false,"given":"Feng","family":"Zhong","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuzhen","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0950-6089","authenticated-orcid":false,"given":"Yongye","family":"Sun","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5689-6174","authenticated-orcid":false,"given":"Jinyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9507-8844","authenticated-orcid":false,"given":"Aiguo","family":"Ma","sequence":"additional","affiliation":[{"name":"Institute of Nutrition and Health, School of Public Health, Qingdao University, 308 Ningxia Road, Qingdao, Shandong, 266021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D4FO05172F\/cit1\/1","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/S0140-6736(15)00151-8","volume":"387","author":"Dheda","year":"2016","journal-title":"Lancet"},{"key":"D4FO05172F\/cit2\/1","volume-title":"Global tuberculosis report 2023","author":"World Health Organization","year":"2023","unstructured":"World Health Organization ,  Global tuberculosis report 2023 ,  World Health Organization ,  Geneva ,  2023"},{"key":"D4FO05172F\/cit3\/1","doi-asserted-by":"crossref","first-page":"e318","DOI":"10.1016\/S1473-3099(20)30792-1","volume":"21","author":"Sinha","year":"2021","journal-title":"Lancet Infect. Dis."},{"key":"D4FO05172F\/cit4\/1","doi-asserted-by":"crossref","first-page":"4825","DOI":"10.1039\/D1FO02827H","volume":"13","author":"Xu","year":"2022","journal-title":"Food Funct."},{"key":"D4FO05172F\/cit5\/1","volume-title":"Nutritional care and support for patients with tuberculosis","author":"World Health Organization","year":"2013","unstructured":"World Health Organization ,  Nutritional care and support for patients with tuberculosis ,  World Health Organization ,  Geneva ,  2013"},{"key":"D4FO05172F\/cit6\/1","volume-title":"Regional strategic plan towards ending TB in the WHO South-East Asia Region: 2021\u20132025","author":"World Health Organization","year":"2021","unstructured":"World Health Organization ,  Regional strategic plan towards ending TB in the WHO South-East Asia Region: 2021\u20132025 ,  World Health Organization ,  Geneva ,  2021"},{"key":"D4FO05172F\/cit7\/1","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1183\/09031936.03.00090702","volume":"21","author":"Sch\u00f6n","year":"2003","journal-title":"Eur. Respir. J."},{"key":"D4FO05172F\/cit8\/1","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1093\/ajcn\/80.2.460","volume":"80","author":"Paton","year":"2004","journal-title":"Am. J. Clin. Nutr."},{"key":"D4FO05172F\/cit9\/1","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1378\/chest.127.2.643","volume":"127","author":"P\u00e9rez-Guzm\u00e1n","year":"2005","journal-title":"Chest"},{"key":"D4FO05172F\/cit10\/1","doi-asserted-by":"crossref","first-page":"b4248","DOI":"10.1136\/bmj.b4248","volume":"339","author":"Martins","year":"2009","journal-title":"BMJ"},{"key":"D4FO05172F\/cit11\/1","first-page":"957","volume":"51","author":"Jahnavi","year":"2010","journal-title":"Singapore Med. J."},{"key":"D4FO05172F\/cit12\/1","doi-asserted-by":"crossref","first-page":"e70032","DOI":"10.1371\/journal.pone.0070032","volume":"8","author":"Ralph","year":"2013","journal-title":"PLoS One"},{"key":"D4FO05172F\/cit13\/1","first-page":"205016","volume":"2015","author":"Farazi","year":"2015","journal-title":"Tuberc. Res. Treat."},{"key":"D4FO05172F\/cit14\/1","doi-asserted-by":"publisher","DOI":"10.1039\/D4FO03449J","author":"Xia","year":"2024","journal-title":"Food Funct."},{"key":"D4FO05172F\/cit15\/1","doi-asserted-by":"crossref","first-page":"04015","DOI":"10.7189\/jogh.12.04015","volume":"12","author":"Tamara","year":"2022","journal-title":"J. Global Health"},{"key":"D4FO05172F\/cit16\/1","first-page":"Cd006086","volume":"6","author":"Grobler","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"key":"D4FO05172F\/cit17\/1","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1001\/jama.1954.02950170003002","volume":"156","author":"Biehl","year":"1954","journal-title":"J. Am. Med. Assoc."},{"key":"D4FO05172F\/cit18\/1","volume-title":"Dietary Guidelines for Chinese Residents\n2023","author":"Chinese Nutrition Society","year":"2023","unstructured":"Chinese Nutrition Society ,  Dietary Guidelines for Chinese Residents\n2023 ,  People's Health Publishing House ,  China ,  2023"},{"key":"D4FO05172F\/cit19\/1","doi-asserted-by":"crossref","first-page":"e448","DOI":"10.1016\/S2214-109X(18)30487-X","volume":"7","author":"Noubiap","year":"2019","journal-title":"Lancet Global Health"},{"key":"D4FO05172F\/cit20\/1","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/S1473-3099(09)70282-8","volume":"9","author":"Dooley","year":"2009","journal-title":"Lancet Infect. Dis."},{"key":"D4FO05172F\/cit21\/1","volume-title":"Systematic Screening for Active Tuberculosis: Principles and Recommendations","author":"World Health Organization","year":"2013","unstructured":"World Health Organization ,  Systematic Screening for Active Tuberculosis: Principles and Recommendations ,  World Health Organization ,  Geneva ,  2013"},{"key":"D4FO05172F\/cit22\/1","volume-title":"IDF Diabetes Atla","author":"International Diabetes Federation","year":"2017","unstructured":"International Diabetes Federation ,  IDF Diabetes Atla ,  International Diabetes Federation ,  Belgium , 8th edn,  2017"},{"key":"D4FO05172F\/cit23\/1","volume-title":"Guidelines for Tuberculosis Prevention and Control in China","author":"Chinese Center for Disease Control and Prevention","year":"2021","unstructured":"Chinese Center for Disease Control and Prevention ,  Guidelines for Tuberculosis Prevention and Control in China ,  People's Health Publishing House ,  China ,  2021"},{"key":"D4FO05172F\/cit24\/1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s11739-012-0802-0","volume":"7","author":"Gatta","year":"2012","journal-title":"Intern. Emerg. Med."},{"key":"D4FO05172F\/cit25\/1","doi-asserted-by":"crossref","first-page":"R192","DOI":"10.1186\/cc9309","volume":"14","author":"de Jager","year":"2010","journal-title":"Crit. Care"},{"key":"D4FO05172F\/cit26\/1","volume-title":"Haemoglobin concentration for the diagnosis of anaemia and assessment of severity","author":"World Health Organization","year":"2011","unstructured":"World Health Organization ,  Haemoglobin concentration for the diagnosis of anaemia and assessment of severity ,  World Health Organization ,  Geneva ,  2011"},{"key":"D4FO05172F\/cit27\/1","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1136\/thx.2010.136242","volume":"65","author":"Ralph","year":"2010","journal-title":"Thorax"},{"key":"D4FO05172F\/cit28\/1","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1183\/09031936.03.00090702","volume":"21","author":"Schon","year":"2003","journal-title":"Eur. Respir. J."},{"key":"D4FO05172F\/cit29\/1","first-page":"4762","volume":"11","author":"Wang","year":"2020","journal-title":"Food Funct."},{"key":"D4FO05172F\/cit30\/1","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1086\/587846","volume":"197","author":"Villamor","year":"2008","journal-title":"J. Infect. Dis."},{"key":"D4FO05172F\/cit31\/1","doi-asserted-by":"crossref","first-page":"e117","DOI":"10.1016\/S1473-3099(20)30148-1","volume":"20","author":"Urbanowski","year":"2020","journal-title":"Lancet Infect. Dis."},{"key":"D4FO05172F\/cit32\/1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/nyas.14003","volume":"1450","author":"Karakochuk","year":"2019","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"D4FO05172F\/cit33\/1","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1111\/j.0894-0959.2004.17603.x","volume":"17","author":"Don","year":"2004","journal-title":"Semin. Dial."},{"key":"D4FO05172F\/cit34\/1","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1186\/1475-2891-10-120","volume":"10","author":"Mehta","year":"2011","journal-title":"Nutr. J."},{"key":"D4FO05172F\/cit35\/1","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.3389\/fimmu.2017.01316","volume":"8","author":"Chandrasekaran","year":"2017","journal-title":"Front. Immunol."},{"key":"D4FO05172F\/cit36\/1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/S0140-6736(10)61889-2","volume":"377","author":"Martineau","year":"2011","journal-title":"Lancet"},{"key":"D4FO05172F\/cit37\/1","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1164\/rccm.201705-0936OC","volume":"196","author":"Ganmaa","year":"2017","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"D4FO05172F\/cit38\/1","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1517\/14740338.5.2.231","volume":"5","author":"Forget","year":"2006","journal-title":"Expert Opin. Drug Saf."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/FO\/D4FO05172F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:20:47Z","timestamp":1782883247000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/16\/1\/102-111\/851367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1,2]]}},"URL":"https:\/\/doi.org\/10.1039\/d4fo05172f","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}