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Med."},{"key":"D4MD00576G\/cit101\/1","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1021\/acs.molpharmaceut.0c01078","volume":"18","author":"Zhou","year":"2021","journal-title":"Mol. Pharmaceutics"},{"key":"D4MD00576G\/cit102\/1","doi-asserted-by":"crossref","first-page":"5865","DOI":"10.1021\/acs.molpharmaceut.3c00717","volume":"20","author":"Wu","year":"2023","journal-title":"Mol. Pharmaceutics"},{"key":"D4MD00576G\/cit103\/1","doi-asserted-by":"crossref","first-page":"114991","DOI":"10.1016\/j.ejmech.2022.114991","volume":"246","author":"Liu","year":"2023","journal-title":"Eur. J. Med. Chem."},{"key":"D4MD00576G\/cit104\/1","doi-asserted-by":"crossref","first-page":"9561","DOI":"10.1021\/acs.jmedchem.3c00239","volume":"66","author":"Liu","year":"2023","journal-title":"J. Med. Chem."},{"key":"D4MD00576G\/cit105\/1","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.2967\/jnumed.123.265593","volume":"64","author":"Harada","year":"2023","journal-title":"J. Nucl. 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A."},{"key":"D4MD00576G\/cit116\/1","doi-asserted-by":"crossref","first-page":"4884","DOI":"10.1073\/pnas.85.13.4884","volume":"85","author":"Wischik","year":"1988","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D4MD00576G\/cit117\/1","doi-asserted-by":"crossref","first-page":"9034","DOI":"10.1073\/pnas.1530287100","volume":"100","author":"Berriman","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D4MD00576G\/cit118\/1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nature23002","volume":"547","author":"Fitzpatrick","year":"2017","journal-title":"Nature"},{"key":"D4MD00576G\/cit119\/1","doi-asserted-by":"crossref","first-page":"168025","DOI":"10.1016\/j.jmb.2023.168025","volume":"435","author":"Shi","year":"2023","journal-title":"J. Mol. Biol."},{"key":"D4MD00576G\/cit120\/1","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1007\/s00401-021-02294-3","volume":"141","author":"Shi","year":"2021","journal-title":"Acta Neuropathol."},{"key":"D4MD00576G\/cit121\/1","doi-asserted-by":"crossref","first-page":"3048","DOI":"10.1038\/s41467-023-38537-y","volume":"14","author":"Merz","year":"2023","journal-title":"Nat. Commun."},{"key":"D4MD00576G\/cit122\/1","doi-asserted-by":"publisher","DOI":"10.1101\/2023.09.22.558671","volume-title":"bioRxiv","author":"Kunach","year":"2023","unstructured":"P.Kunach ,  J.Vaquer-Alicea ,  M. S.Smith ,  R.Hopewell ,  J.Monistrol ,  L.Moquin ,  J.Therriault ,  C.Tissot ,  N.Rahmouni ,  G.Massarweh ,  J. P.Soucy ,  M. C.Guiot ,  B. K.Shoichet ,  P.Rosa-Neto ,  M. I.Diamond  and  S. 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