{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T17:49:37Z","timestamp":1793382577080,"version":"4.5.0"},"reference-count":68,"publisher":"Royal Society of Chemistry (RSC)","issue":"39","license":[{"start":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T00:00:00Z","timestamp":1756944000000},"content-version":"am","delay-in-days":612,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62375208"],"award-info":[{"award-number":["62375208"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Nanoscale"],"abstract":"<jats:p>A high-performance label-free optical fiber biosensor developed for highly sensitive human IgG detection.<\/jats:p>","DOI":"10.1039\/d4nr01883d","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T19:21:06Z","timestamp":1725391266000},"page":"18477-18487","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["An enhanced SPR optical fiber biosensor using Ti\n                    <sub>3<\/sub>\n                    C\n                    <sub>2<\/sub>\n                    T\n                    <sub>\n                      <i>x<\/i>\n                    <\/sub>\n                    MXene\/AuNPs for label-free and sensitive detection of human IgG"],"prefix":"10.1039","volume":"16","author":[{"given":"Jiayi","family":"Zhu","sequence":"first","affiliation":[{"name":"National Engineering Research Center of Fiber Optic Sensing Technology and Networks, Wuhan, 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Zhao","sequence":"additional","affiliation":[{"name":"National Engineering Research Center of Fiber Optic Sensing Technology and Networks, Wuhan, 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binyun","family":"Xia","sequence":"additional","affiliation":[{"name":"National Engineering Research Center of Fiber Optic Sensing Technology and Networks, Wuhan, 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7965-6115","authenticated-orcid":false,"given":"Ning","family":"Wang","sequence":"additional","affiliation":[{"name":"National Engineering Research Center of Fiber Optic Sensing Technology and Networks, Wuhan, 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Jing","sequence":"additional","affiliation":[{"name":"National Engineering Research Center of Fiber Optic Sensing Technology and Networks, Wuhan, 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minxuan","family":"Chen","sequence":"additional","affiliation":[{"name":"National Engineering Research Center of Fiber Optic Sensing Technology and Networks, Wuhan, 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinrui","family":"Xu","sequence":"additional","affiliation":[{"name":"National Engineering Research Center of Fiber Optic Sensing Technology and Networks, Wuhan, 430070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D4NR01883D\/cit1\/1","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1373\/clinchem.2005.051532","volume":"51","author":"Lequin","year":"2005","journal-title":"Clin. Chem."},{"key":"D4NR01883D\/cit2\/1","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1039\/C4NR06461E","volume":"7","author":"Zhao","year":"2015","journal-title":"Nanoscale"},{"key":"D4NR01883D\/cit3\/1","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1007\/s00216-012-6224-z","volume":"404","author":"Nooney","year":"2012","journal-title":"Anal. Bioanal. Chem."},{"key":"D4NR01883D\/cit4\/1","doi-asserted-by":"crossref","first-page":"108154","DOI":"10.1016\/j.bioelechem.2022.108154","volume":"146","author":"Liang","year":"2022","journal-title":"Bioelectrochemistry"},{"key":"D4NR01883D\/cit5\/1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.2116\/analsci.28.51","volume":"28","author":"Tsutsumi","year":"2012","journal-title":"Anal. Sci."},{"key":"D4NR01883D\/cit6\/1","doi-asserted-by":"crossref","first-page":"2308783","DOI":"10.1002\/advs.202308783","volume":"11","author":"Zu","year":"2024","journal-title":"Adv. Sci."},{"key":"D4NR01883D\/cit7\/1","doi-asserted-by":"crossref","first-page":"116014","DOI":"10.1016\/j.bios.2024.116014","volume":"249","author":"Cao","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"D4NR01883D\/cit8\/1","doi-asserted-by":"crossref","first-page":"109878","DOI":"10.1016\/j.optlastec.2023.109878","volume":"168","author":"Zhu","year":"2024","journal-title":"Opt. Laser Technol."},{"key":"D4NR01883D\/cit9\/1","doi-asserted-by":"crossref","first-page":"585","DOI":"10.2174\/1573411019666230616101033","volume":"19","author":"Pradhan","year":"2023","journal-title":"Curr. Anal. Chem."},{"key":"D4NR01883D\/cit10\/1","doi-asserted-by":"crossref","first-page":"140","DOI":"10.3390\/bios11050140","volume":"11","author":"Idil","year":"2021","journal-title":"Biosensors"},{"key":"D4NR01883D\/cit11\/1","doi-asserted-by":"crossref","first-page":"170208","DOI":"10.1016\/j.ijleo.2022.170208","volume":"271","author":"Wei","year":"2022","journal-title":"Optik"},{"key":"D4NR01883D\/cit12\/1","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.3390\/nano11082137","volume":"11","author":"Jing","year":"2021","journal-title":"Nanomaterials"},{"key":"D4NR01883D\/cit13\/1","doi-asserted-by":"crossref","first-page":"131984","DOI":"10.1016\/j.snb.2022.131984","volume":"366","author":"Zhang","year":"2022","journal-title":"Sens. Actuators, B"},{"key":"D4NR01883D\/cit14\/1","doi-asserted-by":"crossref","first-page":"161140","DOI":"10.1016\/j.jallcom.2021.161140","volume":"884","author":"Kim","year":"2021","journal-title":"J. Alloys Compd."},{"key":"D4NR01883D\/cit15\/1","doi-asserted-by":"crossref","first-page":"113798","DOI":"10.1016\/j.bios.2021.113798","volume":"198","author":"Zheng","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"D4NR01883D\/cit16\/1","doi-asserted-by":"crossref","first-page":"123162","DOI":"10.1016\/j.talanta.2021.123162","volume":"240","author":"Shoji","year":"2022","journal-title":"Talanta"},{"key":"D4NR01883D\/cit17\/1","doi-asserted-by":"crossref","first-page":"20516","DOI":"10.1109\/JSEN.2022.3207498","volume":"22","author":"Suhailin","year":"2022","journal-title":"IEEE Sens. J."},{"key":"D4NR01883D\/cit18\/1","doi-asserted-by":"crossref","first-page":"124750","DOI":"10.1016\/j.optcom.2019.124750","volume":"462","author":"Zhang","year":"2020","journal-title":"Opt. Commun."},{"key":"D4NR01883D\/cit19\/1","doi-asserted-by":"crossref","first-page":"106445","DOI":"10.1016\/j.optlastec.2020.106445","volume":"131","author":"Chen","year":"2020","journal-title":"Opt. Laser Technol."},{"key":"D4NR01883D\/cit20\/1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.snb.2017.05.045","volume":"251","author":"Zhang","year":"2017","journal-title":"Sens. Actuators, B"},{"key":"D4NR01883D\/cit21\/1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3390\/s17010002","volume":"17","author":"Wei","year":"2016","journal-title":"Sensors"},{"key":"D4NR01883D\/cit22\/1","doi-asserted-by":"crossref","first-page":"4734","DOI":"10.1109\/JLT.2017.2755668","volume":"35","author":"Ding","year":"2017","journal-title":"J. Lightwave Technol."},{"key":"D4NR01883D\/cit23\/1","doi-asserted-by":"crossref","first-page":"121452","DOI":"10.1016\/j.talanta.2020.121452","volume":"221","author":"Loyez","year":"2021","journal-title":"Talanta"},{"key":"D4NR01883D\/cit24\/1","doi-asserted-by":"crossref","first-page":"195204","DOI":"10.1088\/1361-6463\/ab08bb","volume":"52","author":"Lang","year":"2019","journal-title":"J. Phys. D: Appl. Phys."},{"key":"D4NR01883D\/cit25\/1","doi-asserted-by":"crossref","first-page":"110047","DOI":"10.1016\/j.optlastec.2023.110047","volume":"169","author":"Ying","year":"2024","journal-title":"Opt. Laser Technol."},{"key":"D4NR01883D\/cit26\/1","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1109\/JSEN.2020.3014190","volume":"21","author":"Tan","year":"2021","journal-title":"IEEE Sens. J."},{"key":"D4NR01883D\/cit27\/1","doi-asserted-by":"crossref","first-page":"112156","DOI":"10.1016\/j.measurement.2022.112156","volume":"204","author":"Zhang","year":"2022","journal-title":"Measurement"},{"key":"D4NR01883D\/cit28\/1","doi-asserted-by":"crossref","first-page":"075003","DOI":"10.1088\/2040-8986\/acd862","volume":"25","author":"Kushwaha","year":"2023","journal-title":"J. Opt."},{"key":"D4NR01883D\/cit29\/1","doi-asserted-by":"crossref","first-page":"4566","DOI":"10.1109\/TIM.2018.2886950","volume":"68","author":"Zhangd","year":"2019","journal-title":"IEEE Trans. Instrum. Meas."},{"key":"D4NR01883D\/cit30\/1","doi-asserted-by":"crossref","first-page":"123599","DOI":"10.1016\/j.talanta.2022.123599","volume":"247","author":"Li","year":"2022","journal-title":"Talanta"},{"key":"D4NR01883D\/cit31\/1","doi-asserted-by":"crossref","first-page":"110381","DOI":"10.1016\/j.microc.2024.110381","volume":"200","author":"Wang","year":"2024","journal-title":"Microchem. J."},{"key":"D4NR01883D\/cit32\/1","doi-asserted-by":"crossref","first-page":"214424","DOI":"10.1016\/j.ccr.2022.214424","volume":"458","author":"Philip","year":"2022","journal-title":"Coord. Chem. Rev."},{"key":"D4NR01883D\/cit33\/1","doi-asserted-by":"crossref","first-page":"111324","DOI":"10.1016\/j.bios.2019.111324","volume":"139","author":"Patil","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"D4NR01883D\/cit34\/1","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.bios.2018.11.006","volume":"126","author":"Kaushik","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"D4NR01883D\/cit35\/1","doi-asserted-by":"crossref","first-page":"128485","DOI":"10.1016\/j.optcom.2022.128485","volume":"520","author":"Li","year":"2022","journal-title":"Opt. Commun."},{"key":"D4NR01883D\/cit36\/1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1109\/LPT.2017.2787057","volume":"30","author":"Srivastava","year":"2018","journal-title":"IEEE Photonics Technol. Lett."},{"key":"D4NR01883D\/cit37\/1","doi-asserted-by":"crossref","first-page":"163430","DOI":"10.1016\/j.ijleo.2019.163430","volume":"203","author":"Srivastava","year":"2020","journal-title":"Optik"},{"key":"D4NR01883D\/cit38\/1","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1007\/s12633-020-00558-3","volume":"13","author":"Kumar","year":"2021","journal-title":"Silicon"},{"key":"D4NR01883D\/cit39\/1","doi-asserted-by":"crossref","first-page":"108167","DOI":"10.1016\/j.optlastec.2022.108167","volume":"152","author":"Liu","year":"2022","journal-title":"Opt. Laser Technol."},{"key":"D4NR01883D\/cit40\/1","doi-asserted-by":"crossref","first-page":"2102924","DOI":"10.1002\/advs.202102924","volume":"9","author":"Lei","year":"2022","journal-title":"Adv. Sci."},{"key":"D4NR01883D\/cit41\/1","doi-asserted-by":"crossref","first-page":"112730","DOI":"10.1016\/j.bios.2020.112730","volume":"171","author":"Zhu","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"D4NR01883D\/cit42\/1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1021\/acsanm.9b01889","volume":"3","author":"Chen","year":"2020","journal-title":"ACS Appl. Nano Mater."},{"key":"D4NR01883D\/cit43\/1","first-page":"1","volume":"14","author":"Zhou","year":"2022","journal-title":"IEEE Photonics J."},{"key":"D4NR01883D\/cit44\/1","doi-asserted-by":"crossref","first-page":"111505","DOI":"10.1016\/j.bios.2019.111505","volume":"142","author":"Zhao","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"D4NR01883D\/cit45\/1","doi-asserted-by":"crossref","first-page":"3266","DOI":"10.3390\/s20113266","volume":"20","author":"Qi","year":"2020","journal-title":"Sensors"},{"key":"D4NR01883D\/cit46\/1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1364\/PRJ.439861","volume":"10","author":"Jing","year":"2022","journal-title":"Photonics Res."},{"key":"D4NR01883D\/cit47\/1","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/adma.200801222","volume":"21","author":"Lee","year":"2009","journal-title":"Adv. Mater."},{"key":"D4NR01883D\/cit48\/1","doi-asserted-by":"crossref","first-page":"9847","DOI":"10.1021\/acsanm.4c00316","volume":"7","author":"Yadav","year":"2024","journal-title":"ACS Appl. Nano Mater."},{"key":"D4NR01883D\/cit49\/1","doi-asserted-by":"crossref","first-page":"4215","DOI":"10.1021\/ac0702084","volume":"79","author":"Haiss","year":"2007","journal-title":"Anal. Chem."},{"key":"D4NR01883D\/cit50\/1","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1021\/acsenergylett.0c01290","volume":"5","author":"Shao","year":"2020","journal-title":"ACS Energy Lett."},{"key":"D4NR01883D\/cit51\/1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3390\/bios7020023","volume":"7","author":"Chiavaioli","year":"2017","journal-title":"Biosensors"},{"key":"D4NR01883D\/cit52\/1","doi-asserted-by":"crossref","first-page":"112397","DOI":"10.1016\/j.optmat.2022.112397","volume":"128","author":"Kumar","year":"2022","journal-title":"Opt. Mater."},{"key":"D4NR01883D\/cit53\/1","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.bios.2018.08.076","volume":"121","author":"Kumar","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"D4NR01883D\/cit54\/1","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.bios.2015.06.080","volume":"74","author":"Shi","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"D4NR01883D\/cit55\/1","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.5740\/jaoacint.17-0363","volume":"101","author":"Ershadi","year":"2018","journal-title":"J. AOAC Int."},{"key":"D4NR01883D\/cit56\/1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3390\/bios7020023","volume":"7","author":"Chiavaioli","year":"2017","journal-title":"Biosensors"},{"key":"D4NR01883D\/cit57\/1","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3390\/ma17010098","volume":"17","author":"Wang","year":"2024","journal-title":"Materials"},{"key":"D4NR01883D\/cit58\/1","doi-asserted-by":"crossref","first-page":"8303","DOI":"10.1109\/JSEN.2018.2866169","volume":"18","author":"Wang","year":"2018","journal-title":"IEEE Sens. J."},{"key":"D4NR01883D\/cit59\/1","doi-asserted-by":"crossref","first-page":"101090","DOI":"10.1016\/j.photonics.2022.101090","volume":"52","author":"Mumtaz","year":"2022","journal-title":"Photonics Nanostruct."},{"key":"D4NR01883D\/cit60\/1","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.1007\/s00216-021-03858-8","volume":"414","author":"Zhao","year":"2022","journal-title":"Anal. Bioanal. Chem."},{"key":"D4NR01883D\/cit61\/1","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.snb.2018.08.065","volume":"275","author":"Wang","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"D4NR01883D\/cit62\/1","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1109\/ACCESS.2019.2961751","volume":"8","author":"Liu","year":"2020","journal-title":"IEEE Access"},{"key":"D4NR01883D\/cit63\/1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3390\/bios12030141","volume":"12","author":"Huang","year":"2022","journal-title":"Biosensors"},{"key":"D4NR01883D\/cit64\/1","doi-asserted-by":"crossref","first-page":"116286","DOI":"10.1109\/ACCESS.2021.3106343","volume":"9","author":"Liu","year":"2021","journal-title":"IEEE Access"},{"key":"D4NR01883D\/cit65\/1","doi-asserted-by":"crossref","first-page":"6840","DOI":"10.1364\/BOE.409535","volume":"11","author":"Liu","year":"2020","journal-title":"Biomed. Opt. Express"},{"key":"D4NR01883D\/cit66\/1","doi-asserted-by":"crossref","first-page":"6171","DOI":"10.1021\/acsanm.2c00077","volume":"5","author":"Lin","year":"2022","journal-title":"ACS Appl. Nano Mater."},{"key":"D4NR01883D\/cit67\/1","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1021\/acssensors.7b00918","volume":"3","author":"Chiavaioli","year":"2018","journal-title":"ACS Sens."},{"key":"D4NR01883D\/cit68\/1","doi-asserted-by":"crossref","first-page":"12024","DOI":"10.1021\/acs.analchem.5b01841","volume":"87","author":"Chiavaioli","year":"2015","journal-title":"Anal. Chem."}],"container-title":["Nanoscale"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/NR\/D4NR01883D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T18:01:00Z","timestamp":1783533660000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/nr\/article\/16\/39\/18477-18487\/859461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":68,"journal-issue":{"issue":"39","published-print":{"date-parts":[[2024,10,10]]}},"URL":"https:\/\/doi.org\/10.1039\/d4nr01883d","relation":{},"ISSN":["2040-3364","2040-3372"],"issn-type":[{"value":"2040-3364","type":"print"},{"value":"2040-3372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}