{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T16:51:35Z","timestamp":1793379095578,"version":"4.5.0"},"reference-count":137,"publisher":"Royal Society of Chemistry (RSC)","issue":"22","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"am","delay-in-days":482,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Nanoscale"],"abstract":"<jats:p>This review highlights recent stimulus-responsive antimicrobial nanotherapeutics for ocular infections, focusing on their design, progress, and advantages\/limitations.<\/jats:p>","DOI":"10.1039\/d4nr05462h","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T02:21:18Z","timestamp":1745806878000},"page":"13653-13667","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Stimulus-responsive nanomaterials for ocular antimicrobial therapy"],"prefix":"10.1039","volume":"17","author":[{"given":"Tao","family":"Zhang","sequence":"first","affiliation":[{"name":"Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China"},{"name":"NHC Key Laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai 200031, China"},{"name":"Shanghai Research Center of Ophthalmology and Optometry, Shanghai 200031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9236-9160","authenticated-orcid":false,"given":"Zichao","family":"Luo","sequence":"additional","affiliation":[{"name":"Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China"},{"name":"NHC Key Laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai 200031, China"},{"name":"Shanghai Research Center of Ophthalmology and Optometry, Shanghai 200031, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D4NR05462H\/cit1\/1","first-page":"221","volume":"8","author":"Maria Rosso","year":"2010","journal-title":"Acta Med.-Hist. Adriat."},{"key":"D4NR05462H\/cit2\/1","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1111\/ceo.14113","volume":"50","author":"Cabrera-Aguas","year":"2022","journal-title":"Clin. Exp. Ophthalmol."},{"key":"D4NR05462H\/cit3\/1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.micpath.2016.12.013","volume":"104","author":"Lakhundi","year":"2017","journal-title":"Microb. Pathog."},{"key":"D4NR05462H\/cit4\/1","doi-asserted-by":"crossref","first-page":"103802","DOI":"10.1016\/j.micpath.2019.103802","volume":"138","author":"Niu","year":"2020","journal-title":"Microb. Pathog."},{"key":"D4NR05462H\/cit5\/1","doi-asserted-by":"crossref","first-page":"4490","DOI":"10.1039\/D3BM00505D","volume":"11","author":"Su","year":"2023","journal-title":"Biomater. Sci."},{"key":"D4NR05462H\/cit6\/1","doi-asserted-by":"crossref","first-page":"2302431","DOI":"10.1002\/adma.202302431","volume":"35","author":"Huang","year":"2023","journal-title":"Adv. Mater."},{"key":"D4NR05462H\/cit7\/1","first-page":"202307569","volume":"34","author":"Chen","year":"2024","journal-title":"Adv. Funct. Mater."},{"key":"D4NR05462H\/cit8\/1","doi-asserted-by":"crossref","first-page":"2403142","DOI":"10.1002\/adfm.202403142","volume":"34","author":"Wang","year":"2024","journal-title":"Adv. Funct. Mater."},{"key":"D4NR05462H\/cit9\/1","doi-asserted-by":"crossref","first-page":"20210086","DOI":"10.1002\/EXP.20210086","volume":"2","author":"Lee","year":"2022","journal-title":"Exploration"},{"key":"D4NR05462H\/cit10\/1","doi-asserted-by":"crossref","first-page":"2200435","DOI":"10.1002\/advs.202200435","volume":"9","author":"Li","year":"2022","journal-title":"Adv. Sci."},{"key":"D4NR05462H\/cit11\/1","doi-asserted-by":"crossref","first-page":"2308403","DOI":"10.1002\/smll.202308403","volume":"20","author":"Liu","year":"2024","journal-title":"Small"},{"key":"D4NR05462H\/cit12\/1","doi-asserted-by":"crossref","first-page":"2403399","DOI":"10.1002\/advs.202403399","volume":"11","author":"Wu","year":"2024","journal-title":"Adv. Sci."},{"key":"D4NR05462H\/cit13\/1","doi-asserted-by":"crossref","first-page":"114842","DOI":"10.1016\/j.addr.2023.114842","volume":"197","author":"Yu","year":"2023","journal-title":"Adv. Drug Delivery Rev."},{"key":"D4NR05462H\/cit14\/1","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1021\/acsnano.4c12195","volume":"19","author":"Lu","year":"2025","journal-title":"ACS Nano"},{"key":"D4NR05462H\/cit15\/1","doi-asserted-by":"crossref","first-page":"2407340","DOI":"10.1002\/advs.202407340","volume":"12","author":"Qi","year":"2025","journal-title":"Adv. Sci."},{"key":"D4NR05462H\/cit16\/1","doi-asserted-by":"crossref","first-page":"114770","DOI":"10.1016\/j.addr.2023.114770","volume":"196","author":"Han","year":"2023","journal-title":"Adv. Drug Delivery Rev."},{"key":"D4NR05462H\/cit17\/1","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.jconrel.2023.01.018","volume":"354","author":"Onugwu","year":"2023","journal-title":"J. Controlled Release"},{"key":"D4NR05462H\/cit18\/1","doi-asserted-by":"crossref","first-page":"148978","DOI":"10.1016\/j.cej.2024.148978","volume":"482","author":"Zhou","year":"2024","journal-title":"Chem. Eng. J."},{"key":"D4NR05462H\/cit19\/1","doi-asserted-by":"crossref","first-page":"20230008","DOI":"10.1002\/EXP.20230008","volume":"4","author":"Wong","year":"2024","journal-title":"Exploration"},{"key":"D4NR05462H\/cit20\/1","doi-asserted-by":"crossref","first-page":"2104843","DOI":"10.1002\/advs.202104843","volume":"9","author":"Wang","year":"2022","journal-title":"Adv. Sci."},{"key":"D4NR05462H\/cit21\/1","doi-asserted-by":"crossref","first-page":"9173","DOI":"10.1039\/D4TB01484G","volume":"12","author":"Liu","year":"2024","journal-title":"J. Mater. Chem. B"},{"key":"D4NR05462H\/cit22\/1","doi-asserted-by":"crossref","first-page":"280","DOI":"10.2174\/157339511796196566","volume":"7","author":"Echegaray","year":"2011","journal-title":"Curr. Immunol. Rev."},{"key":"D4NR05462H\/cit23\/1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/imm.12716","volume":"150","author":"Galletti","year":"2017","journal-title":"Immunology"},{"key":"D4NR05462H\/cit24\/1","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S1542-0124(12)70164-7","volume":"4","author":"Nesburn","year":"2006","journal-title":"Ocul. Surf."},{"key":"D4NR05462H\/cit25\/1","doi-asserted-by":"crossref","first-page":"E49","DOI":"10.1016\/S1473-3099(20)30448-5","volume":"21","author":"Brown","year":"2021","journal-title":"Lancet Infect. Dis."},{"key":"D4NR05462H\/cit26\/1","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.jtos.2021.08.007","volume":"28","author":"Stapleton","year":"2023","journal-title":"Ocul. Surf."},{"key":"D4NR05462H\/cit27\/1","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0014-4835(03)00208-2","volume":"78","author":"Moller-Pedersen","year":"2004","journal-title":"Exp. Eye Res."},{"key":"D4NR05462H\/cit28\/1","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.3390\/ma10091086","volume":"10","author":"B\u00f6hm","year":"2017","journal-title":"Materials"},{"key":"D4NR05462H\/cit29\/1","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.tim.2022.01.002","volume":"30","author":"Andre","year":"2022","journal-title":"Trends Microbiol."},{"key":"D4NR05462H\/cit30\/1","doi-asserted-by":"crossref","first-page":"113727","DOI":"10.1016\/j.colsurfb.2023.113727","volume":"234","author":"Jeong","year":"2024","journal-title":"Colloids Surf., B"},{"key":"D4NR05462H\/cit31\/1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1159\/000510196","volume":"29","author":"Schultze","year":"2021","journal-title":"Monogr. Oral Sci."},{"key":"D4NR05462H\/cit32\/1","doi-asserted-by":"crossref","first-page":"140903","DOI":"10.1016\/j.cej.2022.140903","volume":"455","author":"Li","year":"2023","journal-title":"Chem. Eng. J."},{"key":"D4NR05462H\/cit33\/1","doi-asserted-by":"crossref","first-page":"15845","DOI":"10.1021\/acsnano.4c02825","volume":"18","author":"Wang","year":"2024","journal-title":"ACS Nano"},{"key":"D4NR05462H\/cit34\/1","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1039\/D3TB02577B","volume":"12","author":"Zhang","year":"2024","journal-title":"J. Mater. Chem. B"},{"key":"D4NR05462H\/cit35\/1","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1021\/acs.accounts.0c00864","volume":"54","author":"Chang","year":"2021","journal-title":"Acc. Chem. Res."},{"key":"D4NR05462H\/cit36\/1","doi-asserted-by":"crossref","first-page":"10229","DOI":"10.3390\/ijms231810229","volume":"23","author":"Borroni","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"D4NR05462H\/cit37\/1","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1126\/science.284.5418.1318","volume":"284","author":"Costerton","year":"1999","journal-title":"Science"},{"key":"D4NR05462H\/cit38\/1","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/nrmicro.2016.94","volume":"14","author":"Flemming","year":"2016","journal-title":"Nat. Rev. Microbiol."},{"key":"D4NR05462H\/cit39\/1","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1089\/10445490260099700","volume":"21","author":"Zegans","year":"2002","journal-title":"DNA Cell Biol."},{"key":"D4NR05462H\/cit40\/1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3390\/pathogens4010111","volume":"4","author":"Bispo","year":"2015","journal-title":"Pathogens"},{"key":"D4NR05462H\/cit41\/1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3109\/08830185.2012.749400","volume":"32","author":"Pearlman","year":"2013","journal-title":"Int. Rev. Immunol."},{"key":"D4NR05462H\/cit42\/1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/1471-2415-13-57","volume":"13","author":"Abidi","year":"2013","journal-title":"BMC Ophthalmol."},{"key":"D4NR05462H\/cit43\/1","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1111\/opo.13189","volume":"43","author":"Mendonca","year":"2023","journal-title":"Ophthalmic Physiol. Opt."},{"key":"D4NR05462H\/cit44\/1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1128\/microbiolspec.MB-0020-2015","volume":"3","author":"Chandra","year":"2015","journal-title":"Microbiol. Spectrum"},{"key":"D4NR05462H\/cit45\/1","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.mib.2014.02.008","volume":"18","author":"Solano","year":"2014","journal-title":"Curr. Opin. Microbiol."},{"key":"D4NR05462H\/cit46\/1","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.survophthal.2023.06.007","volume":"68","author":"Garcia-Lopez","year":"2023","journal-title":"Surv. Ophthalmol."},{"key":"D4NR05462H\/cit47\/1","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.jconrel.2020.09.014","volume":"327","author":"Han","year":"2020","journal-title":"J. Controlled Release"},{"key":"D4NR05462H\/cit48\/1","doi-asserted-by":"crossref","first-page":"122565","DOI":"10.1016\/j.biomaterials.2024.122565","volume":"308","author":"Xiang","year":"2024","journal-title":"Biomaterials"},{"key":"D4NR05462H\/cit49\/1","doi-asserted-by":"crossref","first-page":"2206437","DOI":"10.1002\/adma.202206437","volume":"34","author":"He","year":"2022","journal-title":"Adv. Mater."},{"key":"D4NR05462H\/cit50\/1","doi-asserted-by":"crossref","first-page":"11136","DOI":"10.1021\/acsnano.2c03971","volume":"16","author":"Zhu","year":"2022","journal-title":"ACS Nano"},{"key":"D4NR05462H\/cit51\/1","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1089\/ars.2013.5447","volume":"20","author":"Paiva","year":"2014","journal-title":"Antioxid. Redox Signaling"},{"key":"D4NR05462H\/cit52\/1","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/imr.12447","volume":"273","author":"El-Benna","year":"2016","journal-title":"Immunol. Rev."},{"key":"D4NR05462H\/cit53\/1","doi-asserted-by":"crossref","first-page":"622534","DOI":"10.3389\/fmicb.2020.622534","volume":"11","author":"Li","year":"2021","journal-title":"Front. Microbiol."},{"key":"D4NR05462H\/cit54\/1","doi-asserted-by":"crossref","first-page":"2310599","DOI":"10.1002\/adma.202310599","volume":"36","author":"Geng","year":"2024","journal-title":"Adv. Mater."},{"key":"D4NR05462H\/cit55\/1","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1038\/s41565-024-01660-y","volume":"19","author":"Wei","year":"2024","journal-title":"Nat. Nanotechnol."},{"key":"D4NR05462H\/cit56\/1","doi-asserted-by":"crossref","first-page":"eado7438","DOI":"10.1126\/sciadv.ado7438","volume":"10","author":"Huang","year":"2024","journal-title":"Sci. Adv."},{"key":"D4NR05462H\/cit57\/1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/nbt.2458","volume":"31","author":"Brynildsen","year":"2013","journal-title":"Nat. Biotechnol."},{"key":"D4NR05462H\/cit58\/1","doi-asserted-by":"crossref","first-page":"111283","DOI":"10.1016\/j.compositesb.2024.111283","volume":"275","author":"Huang","year":"2024","journal-title":"Composites, Part B"},{"key":"D4NR05462H\/cit59\/1","doi-asserted-by":"crossref","first-page":"4575","DOI":"10.1039\/D2TB00667G","volume":"10","author":"Zhang","year":"2022","journal-title":"J. Mater. Chem. B"},{"key":"D4NR05462H\/cit60\/1","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1038\/s41467-022-29862-9","volume":"13","author":"An","year":"2022","journal-title":"Nat. Commun."},{"key":"D4NR05462H\/cit61\/1","doi-asserted-by":"crossref","first-page":"2006742","DOI":"10.1002\/smll.202006742","volume":"17","author":"Chen","year":"2021","journal-title":"Small"},{"key":"D4NR05462H\/cit62\/1","doi-asserted-by":"crossref","first-page":"2307414","DOI":"10.1002\/smll.202307414","volume":"20","author":"Fang","year":"2024","journal-title":"Small"},{"key":"D4NR05462H\/cit63\/1","doi-asserted-by":"crossref","first-page":"2407268","DOI":"10.1002\/adma.202407268","volume":"36","author":"Chen","year":"2024","journal-title":"Adv. Mater."},{"key":"D4NR05462H\/cit64\/1","first-page":"19771","volume":"18","author":"Zhou","year":"2024","journal-title":"ACS Nano"},{"key":"D4NR05462H\/cit65\/1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.survophthal.2015.04.002","volume":"60","author":"Randleman","year":"2015","journal-title":"Surv. Ophthalmol."},{"key":"D4NR05462H\/cit66\/1","doi-asserted-by":"crossref","first-page":"2111066","DOI":"10.1002\/adfm.202111066","volume":"32","author":"Zhu","year":"2022","journal-title":"Adv. Funct. Mater."},{"key":"D4NR05462H\/cit67\/1","doi-asserted-by":"crossref","first-page":"20230163","DOI":"10.1002\/EXP.20230163","volume":"4","author":"Liang","year":"2024","journal-title":"Exploration"},{"key":"D4NR05462H\/cit68\/1","doi-asserted-by":"crossref","first-page":"20210117","DOI":"10.1002\/EXP.20210117","volume":"3","author":"Geng","year":"2023","journal-title":"Exploration"},{"key":"D4NR05462H\/cit69\/1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/BF03353743","volume":"5","author":"Sheng","year":"2013","journal-title":"Nano-Micro Lett."},{"key":"D4NR05462H\/cit70\/1","doi-asserted-by":"crossref","first-page":"6239","DOI":"10.1016\/j.biomaterials.2013.04.066","volume":"34","author":"Sahu","year":"2013","journal-title":"Biomaterials"},{"key":"D4NR05462H\/cit71\/1","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1038\/s41467-019-08722-z","volume":"10","author":"Zhao","year":"2019","journal-title":"Nat. Commun."},{"key":"D4NR05462H\/cit72\/1","doi-asserted-by":"crossref","first-page":"25705","DOI":"10.1021\/jacs.3c09058","volume":"145","author":"Yan","year":"2023","journal-title":"J. Am. Chem. Soc."},{"key":"D4NR05462H\/cit73\/1","doi-asserted-by":"crossref","first-page":"2404107","DOI":"10.1002\/adma.202404107","volume":"36","author":"Lochenie","year":"2024","journal-title":"Adv. Mater."},{"key":"D4NR05462H\/cit74\/1","doi-asserted-by":"crossref","first-page":"33790","DOI":"10.1021\/acsami.1c04996","volume":"13","author":"Bai","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D4NR05462H\/cit75\/1","first-page":"314","volume":"12","author":"Wang","year":"2022","journal-title":"Bioact. Mater."},{"key":"D4NR05462H\/cit76\/1","doi-asserted-by":"crossref","first-page":"20210024","DOI":"10.1002\/EXP.20210024","volume":"1","author":"Wang","year":"2021","journal-title":"Exploration"},{"key":"D4NR05462H\/cit77\/1","doi-asserted-by":"crossref","first-page":"2400366","DOI":"10.1002\/adma.202400366","volume":"36","author":"He","year":"2024","journal-title":"Adv. Mater."},{"key":"D4NR05462H\/cit78\/1","doi-asserted-by":"crossref","first-page":"2211432","DOI":"10.1002\/adma.202211432","volume":"35","author":"He","year":"2023","journal-title":"Adv. Mater."},{"key":"D4NR05462H\/cit79\/1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.3233\/BME-2008-0546","volume":"18","author":"Silva","year":"2008","journal-title":"Bio-Med. Mater. Eng."},{"key":"D4NR05462H\/cit80\/1","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/php.13184","volume":"96","author":"Wilson","year":"2020","journal-title":"Photochem. Photobiol."},{"key":"D4NR05462H\/cit81\/1","first-page":"2003619","volume":"30","author":"Li","year":"2024","journal-title":"Exploration"},{"key":"D4NR05462H\/cit82\/1","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1039\/b311900a","volume":"3","author":"Hamblin","year":"2004","journal-title":"Photochem. Photobiol."},{"key":"D4NR05462H\/cit83\/1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1167\/iovs.10-5593","volume":"52","author":"Shih","year":"2011","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"D4NR05462H\/cit84\/1","doi-asserted-by":"crossref","first-page":"114495","DOI":"10.1016\/j.addr.2022.114495","volume":"189","author":"Canaparo","year":"2022","journal-title":"Adv. Drug Delivery Rev."},{"key":"D4NR05462H\/cit85\/1","doi-asserted-by":"crossref","first-page":"5735","DOI":"10.1038\/s41467-022-33474-8","volume":"13","author":"Geng","year":"2022","journal-title":"Nat. Commun."},{"key":"D4NR05462H\/cit86\/1","doi-asserted-by":"crossref","first-page":"20230100","DOI":"10.1002\/EXP.20230100","volume":"4","author":"Wang","year":"2024","journal-title":"Exploration"},{"key":"D4NR05462H\/cit87\/1","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.1039\/C9BM02046B","volume":"8","author":"Hou","year":"2020","journal-title":"Biomater. Sci."},{"key":"D4NR05462H\/cit88\/1","doi-asserted-by":"crossref","first-page":"106617","DOI":"10.1016\/j.ultsonch.2023.106617","volume":"100","author":"Xu","year":"2023","journal-title":"Ultrason. Sonochem."},{"key":"D4NR05462H\/cit89\/1","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.cej.2018.09.077","volume":"356","author":"Wang","year":"2019","journal-title":"Chem. Eng. J."},{"key":"D4NR05462H\/cit90\/1","doi-asserted-by":"crossref","first-page":"3968","DOI":"10.1021\/acsanm.3c05575","volume":"7","author":"Jin","year":"2024","journal-title":"ACS Appl. Nano Mater."},{"key":"D4NR05462H\/cit91\/1","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.apsb.2023.11.030","volume":"14","author":"Nene","year":"2024","journal-title":"Acta Pharm. Sin. B"},{"key":"D4NR05462H\/cit92\/1","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/PEC.0000000000002761","volume":"38","author":"Nichols","year":"2022","journal-title":"Pediatr. Emerg. Care."},{"key":"D4NR05462H\/cit93\/1","first-page":"100828","volume":"45","author":"Poinard","year":"2024","journal-title":"Ing. Rech. Biomed."},{"key":"D4NR05462H\/cit94\/1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3109\/02656736.2012.665566","volume":"28","author":"Aptel","year":"2012","journal-title":"Int. J. Hyperthermia"},{"key":"D4NR05462H\/cit95\/1","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.mattod.2022.12.004","volume":"63","author":"Zhao","year":"2023","journal-title":"Mater. Today"},{"key":"D4NR05462H\/cit96\/1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1167\/tvst.13.5.5","volume":"13","author":"Park","year":"2024","journal-title":"Transl. Vis. Sci. Technol."},{"key":"D4NR05462H\/cit97\/1","doi-asserted-by":"crossref","first-page":"2310544","DOI":"10.1002\/adfm.202310544","volume":"34","author":"Kong","year":"2024","journal-title":"Adv. Funct. Mater."},{"key":"D4NR05462H\/cit98\/1","first-page":"2414663","author":"Pai","year":"2024","journal-title":"Adv. Mater."},{"key":"D4NR05462H\/cit99\/1","doi-asserted-by":"crossref","first-page":"eadp3611","DOI":"10.1126\/scitranslmed.adp3611","volume":"16","author":"Zhao","year":"2024","journal-title":"Sci. Transl. Med."},{"key":"D4NR05462H\/cit100\/1","doi-asserted-by":"crossref","first-page":"eadl3262","DOI":"10.1126\/sciadv.adl3262","volume":"10","author":"Guo","year":"2024","journal-title":"Sci. Adv."},{"key":"D4NR05462H\/cit101\/1","doi-asserted-by":"crossref","first-page":"eabn1772","DOI":"10.1126\/sciadv.abn1772","volume":"8","author":"Park","year":"2022","journal-title":"Sci. Adv."},{"key":"D4NR05462H\/cit102\/1","doi-asserted-by":"crossref","first-page":"2102327","DOI":"10.1002\/advs.202102327","volume":"8","author":"Cui","year":"2021","journal-title":"Adv. Sci."},{"key":"D4NR05462H\/cit103\/1","doi-asserted-by":"crossref","first-page":"102000","DOI":"10.1016\/j.nantod.2023.102000","volume":"52","author":"Kong","year":"2023","journal-title":"Nano Today"},{"key":"D4NR05462H\/cit104\/1","doi-asserted-by":"crossref","first-page":"2304448","DOI":"10.1002\/adhm.202304448","volume":"13","author":"Zhou","year":"2024","journal-title":"Adv. Healthcare Mater."},{"key":"D4NR05462H\/cit105\/1","doi-asserted-by":"crossref","first-page":"2104657","DOI":"10.1002\/smll.202104657","volume":"18","author":"Shi","year":"2022","journal-title":"Small"},{"key":"D4NR05462H\/cit106\/1","doi-asserted-by":"crossref","first-page":"24055","DOI":"10.1021\/acsnano.3c09034","volume":"17","author":"Meng","year":"2023","journal-title":"ACS Nano"},{"key":"D4NR05462H\/cit107\/1","doi-asserted-by":"crossref","first-page":"141787","DOI":"10.1016\/j.ijbiomac.2025.141787","volume":"306","author":"Lin","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"D4NR05462H\/cit108\/1","doi-asserted-by":"crossref","first-page":"102179","DOI":"10.1016\/j.xcrp.2024.102179","volume":"5","author":"Fan","year":"2024","journal-title":"Cell Rep. Phys. Sci."},{"key":"D4NR05462H\/cit109\/1","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1002\/jat.1609","volume":"30","author":"Cattaneo","year":"2010","journal-title":"J. Appl. Toxicol."},{"key":"D4NR05462H\/cit110\/1","doi-asserted-by":"crossref","first-page":"4060","DOI":"10.2174\/1381612825666181120160959","volume":"24","author":"Xu","year":"2018","journal-title":"Curr. Pharm. Des."},{"key":"D4NR05462H\/cit111\/1","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1021\/acs.chemrestox.0c00340","volume":"34","author":"Borandeh","year":"2021","journal-title":"Chem. Res. Toxicol."},{"key":"D4NR05462H\/cit112\/1","first-page":"1743","volume":"13","author":"Kolle","year":"2016","journal-title":"Part. Fibre Toxicol."},{"key":"D4NR05462H\/cit113\/1","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/978-1-4939-3121-7_19","volume-title":"Nanomaterials in Pharmacology","author":"Yu","year":"2016","unstructured":"G.Yu ,  A.Vaidya ,  D.Sun  and  Z.-R.Lu , in  Nanomaterials in Pharmacology , ed.  Z. R. Lu  and  S. Sakuma ,  2016 , pp.  369\u2013388"},{"key":"D4NR05462H\/cit114\/1","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.3390\/pharmaceutics14050981","volume":"14","author":"Cosert","year":"2022","journal-title":"Pharmaceutics"},{"key":"D4NR05462H\/cit115\/1","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.scib.2018.05.037","volume":"63","author":"Sun","year":"2018","journal-title":"Sci. Bull."},{"key":"D4NR05462H\/cit116\/1","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1631\/jzus.B2300854","volume":"25","author":"Fu","year":"2024","journal-title":"J. Zhejiang Univ., Sci., B"},{"key":"D4NR05462H\/cit117\/1","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.3390\/ijerph19031660","volume":"19","author":"Xie","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"D4NR05462H\/cit118\/1","first-page":"109","volume":"9","author":"Kim","year":"2014","journal-title":"Int. J. Nanomed."},{"key":"D4NR05462H\/cit119\/1","doi-asserted-by":"crossref","first-page":"113727","DOI":"10.1016\/j.colsurfb.2023.113727","volume":"234","author":"Jeong","year":"2024","journal-title":"Colloids Surf., B"},{"key":"D4NR05462H\/cit120\/1","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1016\/j.nano.2017.02.007","volume":"13","author":"Kamaleddin","year":"2017","journal-title":"Nanomed. Nanotechnol."},{"key":"D4NR05462H\/cit121\/1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s12951-022-01326-8","volume":"20","author":"Zhang","year":"2022","journal-title":"J. Nanobiotechnol."},{"key":"D4NR05462H\/cit122\/1","first-page":"2047","volume":"10","author":"Ahmed","year":"2024","journal-title":"Biomater. Sci."},{"key":"D4NR05462H\/cit123\/1","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1039\/C6SC03631G","volume":"8","author":"Dykman","year":"2017","journal-title":"Chem. Sci."},{"key":"D4NR05462H\/cit124\/1","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1016\/j.tibtech.2024.05.002","volume":"42","author":"Zhang","year":"2024","journal-title":"Trends Biotechnol."},{"key":"D4NR05462H\/cit125\/1","doi-asserted-by":"crossref","first-page":"3799","DOI":"10.1002\/smll.201300607","volume":"9","author":"Wang","year":"2013","journal-title":"Small"},{"key":"D4NR05462H\/cit126\/1","first-page":"2296","volume":"11","author":"Guo","year":"2023","journal-title":"Front. Bioeng. Biotechnol."},{"key":"D4NR05462H\/cit127\/1","doi-asserted-by":"crossref","first-page":"5185","DOI":"10.1039\/D3TB00372H","volume":"11","author":"Du","year":"2023","journal-title":"J. Mater. Chem. B"},{"key":"D4NR05462H\/cit128\/1","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1093\/rb\/rbae046","volume":"11","author":"Yin","year":"2024","journal-title":"Regener. Biomater."},{"key":"D4NR05462H\/cit129\/1","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1002\/med.21509","volume":"39","author":"Masse","year":"2019","journal-title":"Med. Res. Rev."},{"key":"D4NR05462H\/cit130\/1","first-page":"2198","volume":"6","author":"Zhu","year":"2019","journal-title":"Adv. Sci."},{"key":"D4NR05462H\/cit131\/1","doi-asserted-by":"crossref","first-page":"e2021022","DOI":"10.5620\/eaht.2021022","volume":"36","author":"Kim","year":"2021","journal-title":"Environ. Anal. Health Toxicol."},{"key":"D4NR05462H\/cit132\/1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1080\/15569527.2024.2387592","volume":"43","author":"Zhao","year":"2024","journal-title":"Cutaneous Ocul. Toxicol."},{"key":"D4NR05462H\/cit133\/1","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.yrtph.2011.08.007","volume":"61","author":"Ema","year":"2011","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"D4NR05462H\/cit134\/1","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1016\/j.msec.2020.111075","volume":"114","author":"Zambrano-Andazol","year":"2020","journal-title":"Mat Sci Eng C-Mater"},{"key":"D4NR05462H\/cit135\/1","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1016\/j.ejpb.2024.114524","volume":"204","author":"Long","year":"2024","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"D4NR05462H\/cit136\/1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1021\/tx100376n","volume":"24","author":"Kuo","year":"2011","journal-title":"Chem. Res. Toxicol."},{"key":"D4NR05462H\/cit137\/1","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1016\/j.biopha.2020.111103","volume":"134","author":"Lu","year":"2021","journal-title":"Biomed. Pharmacother."}],"container-title":["Nanoscale"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/NR\/D4NR05462H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T20:30:14Z","timestamp":1782851414000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/nr\/article\/17\/22\/13653-13667\/860753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":137,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2025,6,5]]}},"URL":"https:\/\/doi.org\/10.1039\/d4nr05462h","relation":{},"ISSN":["2040-3364","2040-3372"],"issn-type":[{"value":"2040-3364","type":"print"},{"value":"2040-3372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}