{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T18:37:06Z","timestamp":1788287826181,"version":"build-2803163510"},"reference-count":26,"publisher":"Royal Society of Chemistry (RSC)","issue":"6","license":[{"start":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T00:00:00Z","timestamp":1767312000000},"content-version":"am","delay-in-days":366,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100010041","name":"Tianjin Science and Technology Committee","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010041","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Org. Biomol. Chem."],"abstract":"<jats:p>\n                    We present a reductive deuteration system using Mg\/CH\n                    <jats:sub>3<\/jats:sub>\n                    OD, which successfully facilitates the conversion of \u03b1,\u03b2-unsaturated esters, amides, and nitriles to their saturated counterparts.\n                  <\/jats:p>","DOI":"10.1039\/d4ob01787k","type":"journal-article","created":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T08:34:43Z","timestamp":1735806883000},"page":"1406-1411","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Magnesium\/methanol-d1: a practical reductive deuteration system for the deuterium labeling of \u03b1,\u03b2-unsaturated esters, nitriles and amides"],"prefix":"10.1039","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8889-4536","authenticated-orcid":false,"given":"Penghui","family":"Ma","sequence":"first","affiliation":[{"name":"College of Pharmacy, Nankai University, Tianjin 300353, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxuan","family":"Li","sequence":"additional","affiliation":[{"name":"School of Science, Tianjin Chengjian University, Tianjin, 300384, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linhua","family":"Sun","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Nankai University, Tianjin 300353, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingli","family":"Yao","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Nankai University, Tianjin 300353, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Nankai University, Tianjin 300353, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfeng","family":"Qin","sequence":"additional","affiliation":[{"name":"Ningjin County Salt Chemical Industrial Park Hebei Huadong Chemical Co., Ltd, Xingtai, 055550 PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingchun","family":"Gu","sequence":"additional","affiliation":[{"name":"School of Science, Tianjin Chengjian University, Tianjin, 300384, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3674-8980","authenticated-orcid":false,"given":"Bin","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Nankai University, Tianjin 300353, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D4OB01787K\/cit1\/1","doi-asserted-by":"crossref","first-page":"6634","DOI":"10.1021\/acs.chemrev.1c00795","volume":"122","author":"Kopf","year":"2022","journal-title":"Chem. Rev."},{"key":"D4OB01787K\/cit2\/1","doi-asserted-by":"crossref","first-page":"3123","DOI":"10.1039\/D0CS01496F","volume":"51","author":"Prakash","year":"2022","journal-title":"Chem. Soc. Rev."},{"key":"D4OB01787K\/cit3\/1","doi-asserted-by":"crossref","first-page":"9988","DOI":"10.1002\/chem.202100635","volume":"27","author":"Vang","year":"2021","journal-title":"Chem. \u2013 Eur. J."},{"key":"D4OB01787K\/cit4\/1","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/s41573-023-00703-8","volume":"22","author":"Di Martino","year":"2023","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D4OB01787K\/cit5\/1","doi-asserted-by":"crossref","first-page":"3022","DOI":"10.1002\/anie.201708903","volume":"57","author":"Atzrodt","year":"2018","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4OB01787K\/cit6\/1","doi-asserted-by":"crossref","first-page":"7744","DOI":"10.1002\/anie.200700039","volume":"46","author":"Atzrodt","year":"2007","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4OB01787K\/cit7\/1","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.1039\/D2CC00344A","volume":"58","author":"Norcott","year":"2022","journal-title":"Chem. Commun."},{"key":"D4OB01787K\/cit8\/1","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1039\/D0QO01299H","volume":"8","author":"Zhou","year":"2021","journal-title":"Org. Chem. Front."},{"key":"D4OB01787K\/cit9\/1","doi-asserted-by":"crossref","first-page":"6291","DOI":"10.1039\/D1CS00907A","volume":"51","author":"Li","year":"2022","journal-title":"Chem. Soc. Rev."},{"key":"D4OB01787K\/cit10\/1","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1002\/cjoc.202300570","volume":"42","author":"Li","year":"2024","journal-title":"Chin. J. Chem."},{"key":"D4OB01787K\/cit11\/1","doi-asserted-by":"crossref","first-page":"13962","DOI":"10.1002\/anie.202005765","volume":"59","author":"Liu","year":"2020","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4OB01787K\/cit12\/1","doi-asserted-by":"crossref","first-page":"17783","DOI":"10.1021\/jacs.2c08278","volume":"144","author":"Wu","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"D4OB01787K\/cit13\/1","doi-asserted-by":"crossref","first-page":"e202304882","DOI":"10.1002\/anie.202304882","volume":"62","author":"Jana","year":"2023","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4OB01787K\/cit14\/1","doi-asserted-by":"crossref","first-page":"e202214433","DOI":"10.1002\/anie.202214433","volume":"62","author":"Suzuki","year":"2023","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4OB01787K\/cit15\/1","doi-asserted-by":"crossref","first-page":"6743","DOI":"10.1021\/jo501093g","volume":"79","author":"An","year":"2014","journal-title":"J. Org. Chem."},{"key":"D4OB01787K\/cit16\/1","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1021\/acs.joc.6b02950","volume":"82","author":"Han","year":"2017","journal-title":"J. Org. Chem."},{"key":"D4OB01787K\/cit17\/1","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.1016\/j.tetlet.2017.05.092","volume":"58","author":"Li","year":"2017","journal-title":"Tetrahedron Lett."},{"key":"D4OB01787K\/cit18\/1","first-page":"567","volume":"59B","author":"Zechmeister","year":"1926","journal-title":"Chem. Ber."},{"key":"D4OB01787K\/cit19\/1","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.2174\/1385272043370087","volume":"8","author":"Lee","year":"2004","journal-title":"Curr. Org. Chem."},{"key":"D4OB01787K\/cit20\/1","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/anie.198100921","volume":"20","author":"Olah","year":"1981","journal-title":"Angew. Chem., Int. Ed. Engl."},{"key":"D4OB01787K\/cit21\/1","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1016\/S0040-4039(00)84542-6","volume":"27","author":"Kwon Youn","year":"1986","journal-title":"Tetrahedron Lett."},{"key":"D4OB01787K\/cit22\/1","doi-asserted-by":"crossref","first-page":"5287","DOI":"10.1016\/S0040-4039(00)96709-1","volume":"28","author":"Hudlicky","year":"1987","journal-title":"Tetrahedron Lett."},{"key":"D4OB01787K\/cit23\/1","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1039\/D1QO01717A","volume":"9","author":"Sun","year":"2022","journal-title":"Org. Chem. Front."},{"key":"D4OB01787K\/cit24\/1","doi-asserted-by":"crossref","first-page":"5117","DOI":"10.1016\/S0040-4039(02)00986-3","volume":"43","author":"Chapelle","year":"2002","journal-title":"Tetrahedron Lett."},{"key":"D4OB01787K\/cit25\/1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1246\/cl.180870","volume":"48","author":"Enomoto","year":"2019","journal-title":"Chem. Lett."},{"key":"D4OB01787K\/cit26\/1","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1055\/s-1996-4248","author":"Zarecki","year":"1996","journal-title":"Synthesis"}],"container-title":["Organic &amp; Biomolecular Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/OB\/D4OB01787K","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T18:08:33Z","timestamp":1782929313000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ob\/article\/23\/6\/1406-1411\/861859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,2,5]]}},"URL":"https:\/\/doi.org\/10.1039\/d4ob01787k","relation":{},"ISSN":["1477-0520","1477-0539"],"issn-type":[{"value":"1477-0520","type":"print"},{"value":"1477-0539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}