{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:39:47Z","timestamp":1790311187220,"version":"4.1.0"},"reference-count":32,"publisher":"Royal Society of Chemistry (RSC)","issue":"8","license":[{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"am","delay-in-days":370,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["24-13-20011"],"award-info":[{"award-number":["24-13-20011"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Org. Biomol. Chem."],"abstract":"<jats:p>\n                    A\n                    <jats:italic>one-pot<\/jats:italic>\n                    multi-component method for pyrimidoazoloazines was developed by the reaction of vicinal amino-nitrile\/ester azoloazines with \u201cAcOH\u2013RC(OEt)\n                    <jats:sub>3<\/jats:sub>\n                    \u2013amine\u201d. A plausible mechanism was proposed and cytotoxicity of pyrimidoazoloazines was studied.\n                  <\/jats:p>","DOI":"10.1039\/d4ob01853b","type":"journal-article","created":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T02:21:51Z","timestamp":1736130111000},"page":"1945-1960","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pyrimido[5,4-\n                    <i>e<\/i>\n                    ]azolo[1,5-\n                    <i>a<\/i>\n                    ]pyrimidines and pyrimido[4,5-\n                    <i>e<\/i>\n                    ][1,2,4]triazolo[5,1-\n                    <i>c<\/i>\n                    ][1,2,4]triazines:\n                    <i>one-pot<\/i>\n                    multi-component synthesis and cytotoxic activity"],"prefix":"10.1039","volume":"23","author":[{"given":"Eva V.","family":"Bersneva","sequence":"first","affiliation":[{"name":"Ural Federal University named after the First President of Russia B.N. Eltsin, Mira st. 19, Yekaterinburg, 620002, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6040-5155","authenticated-orcid":false,"given":"Konstantin V.","family":"Savateev","sequence":"additional","affiliation":[{"name":"Ural Federal University named after the First President of Russia B.N. 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Eltsin, Mira st. 19, Yekaterinburg, 620002, Russian Federation"},{"name":"Department of Biology and Biotechnologies, Ural State Medical University, Yekaterinburg, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria D.","family":"Tokhtueva","sequence":"additional","affiliation":[{"name":"Ural Federal University named after the First President of Russia B.N. Eltsin, Mira st. 19, Yekaterinburg, 620002, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir L.","family":"Rusinov","sequence":"additional","affiliation":[{"name":"Ural Federal University named after the First President of Russia B.N. Eltsin, Mira st. 19, Yekaterinburg, 620002, Russian Federation"},{"name":"Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Science, Sofii Kovalevskoy st. 22, Yekaterinburg, 620137, Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D4OB01853B\/cit1\/1","volume-title":"Global Cancer Observatory: Cancer Today","author":"Ferlay","year":"2020","unstructured":"J.Ferlay ,  M.Ervik ,  F.Lam ,  M.Colombet ,  L.Mery ,  M.Pi\u00f1eros ,  A.Znaor ,  I.Soerjomataram  and  F.Bray ,  Global Cancer Observatory: Cancer Today ,  International Agency for Research on Cancer ,  Lyon, France ,  2020 . Available online:  https:\/\/gco.iarc.fr\/today  (accessed on 22 December 2024)"},{"issue":"2","key":"D4OB01853B\/cit2\/1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.2174\/0929867053363414","volume":"12","author":"Mart\u00ednez","year":"2005","journal-title":"Curr. 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