{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T12:38:44Z","timestamp":1784637524864,"version":"3.55.0"},"reference-count":63,"publisher":"Royal Society of Chemistry (RSC)","issue":"24","license":[{"start":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:00:00Z","timestamp":1716854400000},"content-version":"vor","delay-in-days":148,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82293685"],"award-info":[{"award-number":["82293685"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82293682"],"award-info":[{"award-number":["82293682"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82293680"],"award-info":[{"award-number":["82293680"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22201306"],"award-info":[{"award-number":["22201306"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<jats:p>A mild and distinct \u201csew-and-cut\u201d strategy for the synthesis of \u03b2-amino ketones from cyclic aldimines and sulfonium salts was developed.<\/jats:p>","DOI":"10.1039\/d4ra02817a","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T06:17:35Z","timestamp":1716877055000},"page":"17178-17183","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Base mediated aza-[2 + 1] annulation and regioselective aziridine ring-opening cascade: mild synthesis of functionalized\n                    <i>\u03b2<\/i>\n                    -amino ketones from cyclic\n                    <i>N<\/i>\n                    -sulfonyl aldimines and\n                    <i>\u03b1<\/i>\n                    -carbonyl sulfonium salts"],"prefix":"10.1039","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0303-8966","authenticated-orcid":false,"given":"Xiaoqiang","family":"Lei","sequence":"first","affiliation":[{"name":"State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyan","family":"Sun","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinglan","family":"Guo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangong","family":"Shi","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D4RA02817A\/cit1a\/1","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1021\/jm9013554","volume":"53","author":"Robinson","year":"2010","journal-title":"J. Med. Chem."},{"key":"D4RA02817A\/cit1b\/1","doi-asserted-by":"crossref","first-page":"574","DOI":"10.2165\/00003495-199141040-00006","volume":"41","author":"Milne","year":"1991","journal-title":"Drugs"},{"key":"D4RA02817A\/cit1c\/1","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1016\/j.clinthera.2013.08.012","volume":"35","author":"Kim","year":"2013","journal-title":"Clin. Ther."},{"key":"D4RA02817A\/cit1d\/1","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0041-0101(00)00146-X","volume":"39","author":"Wilson","year":"2001","journal-title":"Toxicon"},{"key":"D4RA02817A\/cit1e\/1","doi-asserted-by":"crossref","first-page":"4012","DOI":"10.1021\/jm9801455","volume":"41","author":"Dimmock","year":"1998","journal-title":"J. Med. Chem."},{"key":"D4RA02817A\/cit1f\/1","doi-asserted-by":"crossref","first-page":"3784","DOI":"10.1016\/j.ejmech.2009.06.020","volume":"44","author":"Rai","year":"2009","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA02817A\/cit1g\/1","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1021\/cb200092v","volume":"6","author":"Sadana","year":"2011","journal-title":"ACS Chem. Biol."},{"key":"D4RA02817A\/cit1h\/1","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1016\/j.bmc.2012.01.028","volume":"20","author":"Wang","year":"2012","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA02817A\/cit2a\/1","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1021\/jo00030a033","volume":"57","author":"Barluenga","year":"1992","journal-title":"J. Org. Chem."},{"key":"D4RA02817A\/cit2b\/1","doi-asserted-by":"crossref","first-page":"5972","DOI":"10.1021\/jo00074a024","volume":"58","author":"Barluenga","year":"1993","journal-title":"J. Org. Chem."},{"key":"D4RA02817A\/cit2c\/1","doi-asserted-by":"crossref","first-page":"3131","DOI":"10.1021\/ol026456y","volume":"4","author":"Keck","year":"2002","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit2d\/1","doi-asserted-by":"crossref","first-page":"5797","DOI":"10.1002\/ejoc.200700409","volume":"35","author":"Ting","year":"2007","journal-title":"Eur. J. Org Chem."},{"key":"D4RA02817A\/cit3a\/1","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1002\/(SICI)1521-3773(19980504)37:8<1044::AID-ANIE1044>3.0.CO;2-E","volume":"37","author":"Arend","year":"1998","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4RA02817A\/cit3b\/1","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1039\/C7QO01079F","volume":"5","author":"Shi","year":"2018","journal-title":"Org. Chem. Front."},{"key":"D4RA02817A\/cit3c\/1","doi-asserted-by":"crossref","first-page":"9098","DOI":"10.1039\/D0RA10772G","volume":"11","author":"Shamna","year":"2021","journal-title":"RSC Adv."},{"key":"D4RA02817A\/cit4a\/1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1021\/ol0361554","volume":"6","author":"Colantoni","year":"2004","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit4b\/1","doi-asserted-by":"crossref","first-page":"3658","DOI":"10.1021\/ol401538b","volume":"15","author":"Miyaji","year":"2013","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit4c\/1","doi-asserted-by":"crossref","first-page":"3670","DOI":"10.1039\/C8OB03034K","volume":"17","author":"Vinogradov","year":"2019","journal-title":"Org. Biomol. Chem."},{"key":"D4RA02817A\/cit4d\/1","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1039\/D3QO01734F","volume":"11","author":"Li","year":"2024","journal-title":"Org. Chem. Front."},{"key":"D4RA02817A\/cit5a\/1","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1021\/ol500929d","volume":"16","author":"Zhang","year":"2014","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit5b\/1","doi-asserted-by":"crossref","first-page":"8561","DOI":"10.1021\/acs.joc.6b01750","volume":"81","author":"Jia","year":"2016","journal-title":"J. Org. Chem."},{"key":"D4RA02817A\/cit6\/1","doi-asserted-by":"crossref","first-page":"2480","DOI":"10.1021\/jacs.5b00719","volume":"137","author":"Cheng","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"D4RA02817A\/cit7a\/1","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1021\/jo102091f","volume":"76","author":"Geng","year":"2011","journal-title":"J. Org. Chem."},{"key":"D4RA02817A\/cit7b\/1","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1002\/adsc.201300662","volume":"356","author":"Crist\u00f3bal-Lecina","year":"2014","journal-title":"Adv. Synth. Catal."},{"key":"D4RA02817A\/cit7c\/1","doi-asserted-by":"crossref","first-page":"6428","DOI":"10.1021\/acs.orglett.7b03332","volume":"19","author":"Llopis","year":"2017","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit8\/1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1039\/D2OB01843H","volume":"21","author":"Garbacz","year":"2023","journal-title":"Org. Biomol. Chem."},{"key":"D4RA02817A\/cit9\/1","doi-asserted-by":"crossref","first-page":"3202","DOI":"10.1002\/adsc.202000504","volume":"362","author":"Li","year":"2020","journal-title":"Adv. Synth. Catal."},{"key":"D4RA02817A\/cit10a\/1","doi-asserted-by":"crossref","first-page":"6762","DOI":"10.1002\/anie.201202136","volume":"51","author":"Luo","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4RA02817A\/cit10b\/1","doi-asserted-by":"crossref","first-page":"11605","DOI":"10.1002\/anie.201407233","volume":"53","author":"Hepburn","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4RA02817A\/cit10c\/1","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1002\/anie.201508964","volume":"55","author":"Mart\u00ednez","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4RA02817A\/cit10d\/1","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1038\/s41467-018-04645-3","volume":"9","author":"Quan","year":"2018","journal-title":"Nat. Commun."},{"key":"D4RA02817A\/cit11a\/1","doi-asserted-by":"crossref","first-page":"5056","DOI":"10.1021\/ja300697c","volume":"134","author":"Nishimura","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"D4RA02817A\/cit11b\/1","doi-asserted-by":"crossref","first-page":"7540","DOI":"10.1002\/anie.201302861","volume":"52","author":"Yang","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4RA02817A\/cit11c\/1","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1021\/ja3110818","volume":"135","author":"Wang","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"D4RA02817A\/cit11d\/1","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1021\/acs.orglett.7b03639","volume":"20","author":"Chen","year":"2018","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit12a\/1","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1002\/anie.201508804","volume":"55","author":"Xia","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4RA02817A\/cit12b\/1","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1021\/acs.orglett.5b03664","volume":"18","author":"Yan","year":"2016","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit12c\/1","doi-asserted-by":"crossref","first-page":"11584","DOI":"10.1002\/anie.201705829","volume":"56","author":"Kim","year":"2017","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4RA02817A\/cit13a\/1","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1021\/acs.orglett.5b00196","volume":"17","author":"Zhang","year":"2015","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit13b\/1","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1021\/acs.orglett.5b03551","volume":"18","author":"Lai","year":"2016","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit13c\/1","doi-asserted-by":"crossref","first-page":"3118","DOI":"10.1002\/asia.201601149","volume":"11","author":"Cui","year":"2016","journal-title":"Chem.\u2013Asian J."},{"key":"D4RA02817A\/cit13d\/1","doi-asserted-by":"crossref","first-page":"3643","DOI":"10.1021\/acs.orglett.8b01422","volume":"20","author":"Liu","year":"2018","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit13e\/1","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1002\/adsc.202101418","volume":"364","author":"Tang","year":"2022","journal-title":"Adv. Synth. Catal."},{"key":"D4RA02817A\/cit14\/1","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1039\/C6SC05450A","volume":"8","author":"Liu","year":"2017","journal-title":"Chem. Sci."},{"key":"D4RA02817A\/cit15a\/1","doi-asserted-by":"crossref","first-page":"17266","DOI":"10.1021\/ja807937m","volume":"130","author":"Rommel","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"D4RA02817A\/cit15b\/1","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1021\/acs.orglett.8b00228","volume":"20","author":"Spielmann","year":"2018","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit15c\/1","doi-asserted-by":"crossref","first-page":"4881","DOI":"10.1039\/C8OB01231H","volume":"16","author":"Wang","year":"2018","journal-title":"Org. Biomol. Chem."},{"key":"D4RA02817A\/cit15d\/1","doi-asserted-by":"crossref","first-page":"9179","DOI":"10.1021\/acs.joc.9b01128","volume":"84","author":"Zhou","year":"2019","journal-title":"J. Org. Chem."},{"key":"D4RA02817A\/cit15e\/1","doi-asserted-by":"crossref","first-page":"3868","DOI":"10.1021\/acs.orglett.1c01001","volume":"23","author":"Reddy","year":"2021","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit15f\/1","doi-asserted-by":"crossref","first-page":"15805","DOI":"10.1021\/acs.joc.3c01878","volume":"88","author":"Xie","year":"2023","journal-title":"J. Org. Chem."},{"key":"D4RA02817A\/cit16a\/1","doi-asserted-by":"crossref","first-page":"9984","DOI":"10.1002\/chem.201501632","volume":"21","author":"Zheng","year":"2015","journal-title":"Chem.\u2013Eur. J."},{"key":"D4RA02817A\/cit16b\/1","doi-asserted-by":"crossref","first-page":"2992","DOI":"10.1039\/C8QO00877A","volume":"5","author":"Sun","year":"2018","journal-title":"Org. Chem. Front."},{"key":"D4RA02817A\/cit17\/1","doi-asserted-by":"crossref","first-page":"6268","DOI":"10.1021\/acs.orglett.7b02704","volume":"19","author":"Wu","year":"2017","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit18\/1","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1021\/ol9027072","volume":"12","author":"Zhu","year":"2010","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit19a\/1","doi-asserted-by":"crossref","first-page":"7881","DOI":"10.1021\/cr400553c","volume":"114","author":"Degennaro","year":"2014","journal-title":"Chem. Rev."},{"key":"D4RA02817A\/cit19b\/1","doi-asserted-by":"crossref","first-page":"7425","DOI":"10.1002\/anie.201900613","volume":"58","author":"Pan","year":"2019","journal-title":"Angew. Chem., Int. Ed."},{"key":"D4RA02817A\/cit20a\/1","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1021\/ol000130c","volume":"2","author":"Dauban","year":"2000","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit20b\/1","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1021\/ol0200899","volume":"4","author":"Duran","year":"2002","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit21\/1","doi-asserted-by":"crossref","first-page":"11331","DOI":"10.1016\/j.tet.2006.07.099","volume":"62","author":"Guthikonda","year":"2006","journal-title":"Tetrahedron"},{"key":"D4RA02817A\/cit22\/1","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1039\/C1CS15140A","volume":"41","author":"Stankovi\u0107","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"D4RA02817A\/cit23a\/1","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1021\/ol0200899","volume":"4","author":"Duran","year":"2002","journal-title":"Org. Lett."},{"key":"D4RA02817A\/cit23b\/1","doi-asserted-by":"crossref","first-page":"7438","DOI":"10.1021\/jo201209x","volume":"76","author":"Malik","year":"2011","journal-title":"J. Org. Chem."},{"key":"D4RA02817A\/cit24\/1","doi-asserted-by":"crossref","first-page":"e202300300","DOI":"10.1002\/ejoc.202300300","volume":"26","author":"Lin","year":"2023","journal-title":"Eur. J. Org Chem."}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/RA\/D4RA02817A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T03:47:37Z","timestamp":1782964057000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ra\/article\/14\/24\/17178-17183\/866056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":63,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2024,5,22]]}},"URL":"https:\/\/doi.org\/10.1039\/d4ra02817a","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D4RA02817A\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D4RA02817A\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D4RA02817A\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D4RA02817A\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D4RA02817A\/v1\/review1","asserted-by":"object"}]},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}