{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T02:30:18Z","timestamp":1791599418323,"version":"4.3.4"},"reference-count":235,"publisher":"Royal Society of Chemistry (RSC)","issue":"48","license":[{"start":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T00:00:00Z","timestamp":1731369600000},"content-version":"vor","delay-in-days":316,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100007446","name":"King Khalid University","doi-asserted-by":"publisher","award":["RGP2\/255\/45"],"award-info":[{"award-number":["RGP2\/255\/45"]}],"id":[{"id":"10.13039\/501100007446","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<jats:p>Heterocyclic compounds represent a prominent class of molecules with diverse pharmacological activities.<\/jats:p>","DOI":"10.1039\/d4ra06290f","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T03:18:56Z","timestamp":1731381536000},"page":"35769-35970","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Exploring heterocyclic scaffolds in carbonic anhydrase inhibition: a decade of structural and therapeutic insights"],"prefix":"10.1039","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6647-9697","authenticated-orcid":false,"given":"Nafeesa","family":"Naeem","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amina","family":"Sadiq","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Govt. College Women University, Sialkot 51300, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gehan Ahmed","family":"Othman","sequence":"additional","affiliation":[{"name":"Biology Department, College of Science, King Khalid University, Abha, 61421, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Habab M.","family":"Yassin","sequence":"additional","affiliation":[{"name":"Biology Department, College of Science, King Khalid University, Abha, 61421, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9463-9398","authenticated-orcid":false,"given":"Ehsan Ullah","family":"Mughal","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D4RA06290F\/cit1\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2174\/18741045-v16-e2202280","volume":"16","author":"Qadir","year":"2022","journal-title":"Open Med. Chem. J."},{"key":"D4RA06290F\/cit2\/1","doi-asserted-by":"crossref","first-page":"100606","DOI":"10.1016\/j.rechem.2022.100606","volume":"4","author":"Kabir","year":"2022","journal-title":"Results Chem."},{"key":"D4RA06290F\/cit3\/1","doi-asserted-by":"crossref","first-page":"16413","DOI":"10.1039\/D3RA01888A","volume":"13","author":"Jassas","year":"2023","journal-title":"RSC Adv."},{"key":"D4RA06290F\/cit4\/1","doi-asserted-by":"crossref","first-page":"19764","DOI":"10.1039\/D2RA03081K","volume":"12","author":"Obaid","year":"2022","journal-title":"RSC Adv."},{"key":"D4RA06290F\/cit5\/1","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.ejmech.2018.08.040","volume":"158","author":"Kalaria","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit6\/1","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1039\/D1QO01602D","volume":"9","author":"Srivastava","year":"2022","journal-title":"Org. Chem. Front."},{"key":"D4RA06290F\/cit7\/1","doi-asserted-by":"crossref","first-page":"133970","DOI":"10.1016\/j.molstruc.2022.133970","volume":"1271","author":"Al-Jumaili","year":"2023","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit8\/1","doi-asserted-by":"crossref","first-page":"44247","DOI":"10.1039\/D0RA09198G","volume":"10","author":"Heravi","year":"2020","journal-title":"RSC Adv."},{"key":"D4RA06290F\/cit9\/1","doi-asserted-by":"crossref","first-page":"773","DOI":"10.3109\/14756366.2011.617882","volume":"27","author":"Husain","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit10\/1","first-page":"141","volume":"9","author":"Al-Mulla","year":"2017","journal-title":"Der Pharma Chem."},{"key":"D4RA06290F\/cit11\/1","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.procbio.2022.06.009","volume":"120","author":"Obaid","year":"2022","journal-title":"Process Biochem."},{"key":"D4RA06290F\/cit12\/1","first-page":"2947","volume":"3","author":"Arora","year":"2012","journal-title":"Int. J. Pharm. Sci. Res."},{"key":"D4RA06290F\/cit13\/1","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1016\/j.bmcl.2010.05.009","volume":"20","author":"Supuran","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D4RA06290F\/cit14\/1","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1517\/13543776.10.5.575","volume":"10","author":"Supuran","year":"2000","journal-title":"Expert Opin. Ther. Pat."},{"key":"D4RA06290F\/cit15\/1","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1002\/ddr.22051","volume":"84","author":"Zhu","year":"2023","journal-title":"Drug Dev. Res."},{"key":"D4RA06290F\/cit16\/1","doi-asserted-by":"crossref","first-page":"759","DOI":"10.3109\/14756366.2012.672983","volume":"27","author":"Supuran","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit17\/1","doi-asserted-by":"crossref","first-page":"6112","DOI":"10.1039\/D3QO01474F","volume":"10","author":"Zuo","year":"2023","journal-title":"Org. Chem. Front."},{"key":"D4RA06290F\/cit18\/1","doi-asserted-by":"crossref","first-page":"8638","DOI":"10.3390\/ijms25168638","volume":"25","author":"Jing","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"D4RA06290F\/cit19\/1","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1080\/13543776.2018.1523897","volume":"28","author":"Supuran","year":"2018","journal-title":"Expert Opin. Ther. Pat."},{"key":"D4RA06290F\/cit20\/1","doi-asserted-by":"crossref","first-page":"3051","DOI":"10.1021\/jm701526d","volume":"51","author":"Thiry","year":"2008","journal-title":"J. Med. Chem."},{"key":"D4RA06290F\/cit21\/1","doi-asserted-by":"crossref","first-page":"112923","DOI":"10.1016\/j.ejmech.2020.112923","volume":"209","author":"Kumar","year":"2021","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit22\/1","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1517\/13543776.2013.794788","volume":"23","author":"Masini","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"D4RA06290F\/cit23\/1","doi-asserted-by":"crossref","first-page":"879","DOI":"10.2174\/156802607780636762","volume":"7","author":"De Simone","year":"2007","journal-title":"Curr. Top. Med. Chem."},{"key":"D4RA06290F\/cit24\/1","doi-asserted-by":"crossref","first-page":"855","DOI":"10.2174\/156802607780636726","volume":"7","author":"Thiry","year":"2007","journal-title":"Curr. Top. Med. Chem."},{"key":"D4RA06290F\/cit25\/1","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.4155\/fmc-2021-0222","volume":"13","author":"T Supuran","year":"2021","journal-title":"Future Med. Chem."},{"key":"D4RA06290F\/cit26\/1","doi-asserted-by":"crossref","first-page":"345","DOI":"10.3109\/14756366.2015.1122001","volume":"31","author":"Supuran","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit27\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0163-7258(96)00198-2","volume":"74","author":"Lindskog","year":"1997","journal-title":"Pharmacol. Ther."},{"key":"D4RA06290F\/cit28\/1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/17460441.2017.1253677","volume":"12","author":"Supuran","year":"2017","journal-title":"Expert Opin. Drug Discovery"},{"key":"D4RA06290F\/cit29\/1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1517\/13543776.12.2.217","volume":"12","author":"Supuran","year":"2002","journal-title":"Expert Opin. Ther. Pat."},{"key":"D4RA06290F\/cit30\/1","first-page":"291","volume-title":"Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications","author":"McKenna","year":"2013","unstructured":"R.McKenna  and  C. T.Supuran ,  Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications ,  2013 ,  pp. 291\u2013323"},{"key":"D4RA06290F\/cit31\/1","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1517\/13543776.2012.707646","volume":"22","author":"Aggarwal","year":"2012","journal-title":"Expert Opin. Ther. Pat."},{"key":"D4RA06290F\/cit32\/1","doi-asserted-by":"crossref","first-page":"5636","DOI":"10.1021\/ja00197a021","volume":"111","author":"Merz Jr","year":"1989","journal-title":"J. Am. Chem. Soc."},{"key":"D4RA06290F\/cit33\/1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.4324\/9780203475300","volume-title":"Carbonic Anhydrase","author":"Supuran","year":"2004","unstructured":"C. T.Supuran , in  Carbonic Anhydrase ,  CRC press ,  2004 ,  pp. 13\u201336"},{"key":"D4RA06290F\/cit34\/1","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1042\/CS20210040","volume":"135","author":"Supuran","year":"2021","journal-title":"Clin. Sci."},{"key":"D4RA06290F\/cit35\/1","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.3390\/catal10091008","volume":"10","author":"Angeli","year":"2020","journal-title":"Catalysts"},{"key":"D4RA06290F\/cit36\/1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.plantsci.2017.12.002","volume":"268","author":"DiMario","year":"2018","journal-title":"Plant Sci."},{"key":"D4RA06290F\/cit37\/1","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1111\/j.1469-185X.1972.tb01079.x","volume":"47","author":"Carter","year":"1972","journal-title":"Biol. Rev."},{"key":"D4RA06290F\/cit38\/1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/B978-0-12-816476-1.00001-0","author":"Nocentini","year":"2019","journal-title":"Carbonic Anhydrases"},{"key":"D4RA06290F\/cit39\/1","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/cjoc.202200406","volume":"41","author":"Chen","year":"2023","journal-title":"Chin. J. Chem."},{"key":"D4RA06290F\/cit40\/1","doi-asserted-by":"crossref","first-page":"17852","DOI":"10.1021\/acsnano.4c04022","volume":"18","author":"Zhao","year":"2024","journal-title":"ACS Nano"},{"key":"D4RA06290F\/cit41\/1","doi-asserted-by":"crossref","first-page":"1388015","DOI":"10.3389\/fgene.2024.1388015","volume":"15","author":"Xu","year":"2024","journal-title":"Front. Genet."},{"key":"D4RA06290F\/cit42\/1","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1016\/j.bmc.2012.04.044","volume":"21","author":"Hassan","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit43\/1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.cbpa.2010.06.161","volume":"157","author":"Gilmour","year":"2010","journal-title":"Comp. Biochem. Physiol., Part A: Mol. Integr. Physiol."},{"key":"D4RA06290F\/cit44\/1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/med.10025","volume":"23","author":"Supuran","year":"2003","journal-title":"Med. Res. Rev."},{"key":"D4RA06290F\/cit45\/1","doi-asserted-by":"crossref","first-page":"4336","DOI":"10.1016\/j.bmc.2007.04.020","volume":"15","author":"Supuran","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit46\/1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3390\/metabo7040056","volume":"7","author":"Supuran","year":"2017","journal-title":"Metabolites"},{"key":"D4RA06290F\/cit47\/1","volume-title":"X-Ray Crystallography of Carbonic Anhydrase Inhibitors and its Importance in Drug Design","author":"Alterio","year":"2009","unstructured":"V.Alterio ,  A.Di Fiore ,  K.D'Ambrosio ,  C. T.Supuran  and  G.De Simone ,  X-Ray Crystallography of Carbonic Anhydrase Inhibitors and its Importance in Drug Design ,  Wiley ,  Hoboken, New Jersey ,  2009"},{"key":"D4RA06290F\/cit48\/1","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1042\/BCJ20160115","volume":"473","author":"Supuran","year":"2016","journal-title":"Biochem. J."},{"key":"D4RA06290F\/cit49\/1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-3-030-12780-0_1","volume-title":"Carbonic Anhydrase as Drug Target: Thermodynamics and Structure of Inhibitor Binding","author":"Baranauskien\u0117","year":"2019","unstructured":"L.Baranauskien\u0117  and  D.Matulis ,  Carbonic Anhydrase as Drug Target: Thermodynamics and Structure of Inhibitor Binding ,  2019 ,  pp. 3\u201314"},{"key":"D4RA06290F\/cit50\/1","doi-asserted-by":"crossref","first-page":"267","DOI":"10.3109\/14756366.2012.737323","volume":"28","author":"Aggarwal","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit51\/1","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1021\/ar9501232","volume":"29","author":"Christianson","year":"1996","journal-title":"Acc. Chem. Res."},{"key":"D4RA06290F\/cit52\/1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/B978-0-12-823974-2.00014-0","volume-title":"Metalloenzymes","author":"Supuran","year":"2024","unstructured":"C. T.Supuran , in  Metalloenzymes ,  Elsevier ,  2024 ,  pp. 139\u2013156"},{"key":"D4RA06290F\/cit53\/1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.3109\/14756366.2014.913587","volume":"30","author":"Winum","year":"2015","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit54\/1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1080\/13543776.2019.1629419","volume":"29","author":"Zamanova","year":"2019","journal-title":"Expert Opin. Ther. Pat."},{"key":"D4RA06290F\/cit55\/1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0065-2423(06)42005-9","volume":"42","author":"Pastorekova","year":"2006","journal-title":"Adv. Clin. Chem."},{"key":"D4RA06290F\/cit56\/1","doi-asserted-by":"crossref","first-page":"6380","DOI":"10.3390\/molecules26216380","volume":"26","author":"Ciccone","year":"2021","journal-title":"Molecules"},{"key":"D4RA06290F\/cit57\/1","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1517\/13543776.13.10.1545","volume":"13","author":"Supuran","year":"2003","journal-title":"Expert Opin. Ther. Pat."},{"key":"D4RA06290F\/cit58\/1","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1080\/14756366.2022.2121393","volume":"37","author":"Supuran","year":"2022","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit59\/1","first-page":"709","volume":"32","author":"Bibi","year":"2019","journal-title":"Pak. J. Pharm. Sci."},{"key":"D4RA06290F\/cit60\/1","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/B978-0-12-816476-1.00015-0","volume-title":"Carbonic Anhydrases","author":"Berrino","year":"2019","unstructured":"E.Berrino  and  F.Carta , in  Carbonic Anhydrases ,  Elsevier ,  2019 ,  pp. 311\u2013329"},{"key":"D4RA06290F\/cit61\/1","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.3390\/cancers12071723","volume":"12","author":"Haapasalo","year":"2020","journal-title":"Cancers"},{"key":"D4RA06290F\/cit62\/1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/978-94-007-7359-2_14","volume-title":"Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications","author":"Ruusuvuori","year":"2014","unstructured":"E.Ruusuvuori  and  K.Kaila ,  Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications ,  2014 ,  271\u2013290"},{"key":"D4RA06290F\/cit63\/1","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1517\/13543776.2013.780598","volume":"23","author":"Carta","year":"2013","journal-title":"Expert Opin. Ther. Pat."},{"key":"D4RA06290F\/cit64\/1","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/B978-0-12-816476-1.00014-9","volume-title":"Carbonic Anhydrases","author":"Bua","year":"2019","unstructured":"S.Bua ,  A.Nocentini  and  C. T.Supuran , in  Carbonic Anhydrases ,  Elsevier ,  2019 ,  pp. 287\u2013309"},{"key":"D4RA06290F\/cit65\/1","first-page":"11","volume":"1","author":"Pandey","year":"2022","journal-title":"J. Res. Appl. Sci. Biotechnol."},{"key":"D4RA06290F\/cit66\/1","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1517\/17425255.2016.1154534","volume":"12","author":"Supuran","year":"2016","journal-title":"Expert Opin. Drug Metab. Toxicol."},{"key":"D4RA06290F\/cit67\/1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1201\/9781003522980-16","volume-title":"Chandler and Grant's Glaucoma","author":"Challa","year":"2024","unstructured":"P.Challa  and  D. L.Epstein , in  Chandler and Grant's Glaucoma ,  CRC Press ,  2024 ,  pp. 159\u2013164"},{"key":"D4RA06290F\/cit68\/1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1093\/toxsci\/18.1.137","volume":"18","author":"Durand-Cavagna","year":"1992","journal-title":"Toxicol. Sci."},{"key":"D4RA06290F\/cit69\/1","doi-asserted-by":"crossref","first-page":"108344","DOI":"10.1016\/j.exer.2020.108344","volume":"202","author":"Ambrosio","year":"2021","journal-title":"Exp. Eye Res."},{"key":"D4RA06290F\/cit70\/1","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1185\/030079908X292038","volume":"24","author":"Lafuma","year":"2008","journal-title":"Curr. Med. Res. Opin."},{"key":"D4RA06290F\/cit71\/1","doi-asserted-by":"crossref","first-page":"109444","DOI":"10.1016\/j.exer.2023.109444","volume":"232","author":"Sharif","year":"2023","journal-title":"Exp. Eye Res."},{"key":"D4RA06290F\/cit72\/1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.51329\/mehdiophthal1443","volume":"11","author":"Shahsuvaryan","year":"2022","journal-title":"Med. Hypothesis, Discovery Innovation Ophthalmol."},{"key":"D4RA06290F\/cit73\/1","first-page":"425","volume":"105","author":"Syed","year":"2021","journal-title":"Med. Clin."},{"key":"D4RA06290F\/cit74\/1","first-page":"255","volume-title":"Carbonic Anhydrase","author":"Mincione","year":"2004","unstructured":"F.Mincione ,  L.Menabuoni  and  C. T.Supuran , in  Carbonic Anhydrase ,  CRC Press ,  2004 ,  pp. 255\u2013266"},{"key":"D4RA06290F\/cit75\/1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0163-7258(00)00105-4","volume":"89","author":"Clapham","year":"2001","journal-title":"Pharmacol. Ther."},{"key":"D4RA06290F\/cit76\/1","doi-asserted-by":"crossref","first-page":"655","DOI":"10.2174\/138161208783877820","volume":"14","author":"Simone","year":"2008","journal-title":"Curr. Pharm. Des."},{"key":"D4RA06290F\/cit77\/1","first-page":"3","volume-title":"Topics in Anti-Cancer Research","volume":"5","author":"Mboge","year":"2015","unstructured":"M. Y.Mboge ,  R.McKenna  and  S. C.Frost ,  Topics in Anti-Cancer Research ,  2015 ,  5 ,  3"},{"key":"D4RA06290F\/cit78\/1","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1080\/13543776.2022.2083502","volume":"32","author":"Nerella","year":"2022","journal-title":"Expert Opin. Ther. Pat."},{"key":"D4RA06290F\/cit79\/1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3390\/metabo8010019","volume":"8","author":"Mboge","year":"2018","journal-title":"Metabolites"},{"key":"D4RA06290F\/cit80\/1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/jbmr.5650060406","volume":"6","author":"Pierce Jr","year":"1991","journal-title":"J. Bone Miner. Res."},{"key":"D4RA06290F\/cit81\/1","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.3390\/cimb45020089","volume":"45","author":"Alkhayal","year":"2023","journal-title":"Curr. Issues Mol. Biol."},{"key":"D4RA06290F\/cit82\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/ar3929","volume":"14","author":"Chang","year":"2012","journal-title":"Arthritis Res. Ther."},{"key":"D4RA06290F\/cit83\/1","first-page":"169","volume-title":"Annual Reports in Medicinal Chemistry","volume":"22","author":"Hayward","year":"1987","unstructured":"M. A.Hayward  and  T. J.Caggiano , in  Annual Reports in Medicinal Chemistry ,  Elsevier ,  1987 ,  vol. 22 ,  pp. 169\u2013178"},{"key":"D4RA06290F\/cit84\/1","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.ejmech.2013.09.027","volume":"69","author":"S\u0142awi\u0144ski","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit85\/1","doi-asserted-by":"crossref","first-page":"2925","DOI":"10.1016\/j.bmc.2013.03.077","volume":"21","author":"Aksu","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit86\/1","first-page":"1","volume":"2013","author":"Berber","year":"2013","journal-title":"Arthritis Res. Ther."},{"key":"D4RA06290F\/cit87\/1","doi-asserted-by":"crossref","first-page":"305","DOI":"10.3109\/14756366.2011.639016","volume":"28","author":"Ayvaz","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit88\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejmech.2013.04.035","volume":"66","author":"Wang","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit89\/1","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.2042-7158.2012.01609.x","volume":"65","author":"B\u00fcy\u00fckkidan","year":"2013","journal-title":"J. Pharm. Pharmacol."},{"key":"D4RA06290F\/cit90\/1","doi-asserted-by":"crossref","first-page":"299","DOI":"10.3109\/14756366.2012.677838","volume":"28","author":"Karatas","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit91\/1","doi-asserted-by":"crossref","first-page":"328","DOI":"10.3109\/14756366.2011.651465","volume":"28","author":"\u015een","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit92\/1","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.ejmech.2013.06.003","volume":"66","author":"Suthar","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit93\/1","doi-asserted-by":"crossref","first-page":"384","DOI":"10.3109\/21691401.2012.761226","volume":"41","author":"Gen\u00e7er","year":"2013","journal-title":"Artif. Cells, Nanomed., Biotechnol."},{"key":"D4RA06290F\/cit94\/1","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.ejmech.2013.01.030","volume":"62","author":"Gao","year":"2013","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit95\/1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.3109\/14756366.2012.720573","volume":"28","author":"Allouche","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit96\/1","doi-asserted-by":"crossref","first-page":"6945","DOI":"10.1016\/j.bmc.2014.10.041","volume":"22","author":"Ceruso","year":"2014","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit97\/1","doi-asserted-by":"crossref","first-page":"3684","DOI":"10.1016\/j.bmc.2014.05.009","volume":"22","author":"Ghorab","year":"2014","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit98\/1","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1016\/j.bmc.2014.03.029","volume":"22","author":"Mojzych","year":"2014","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit99\/1","doi-asserted-by":"crossref","first-page":"17356","DOI":"10.3390\/molecules191117356","volume":"19","author":"Rutkauskas","year":"2014","journal-title":"Molecules"},{"key":"D4RA06290F\/cit100\/1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.ejmech.2014.06.074","volume":"84","author":"S\u0142awi\u0144ski","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit101\/1","doi-asserted-by":"crossref","first-page":"9435","DOI":"10.1021\/jm501003k","volume":"57","author":"Dudutiene","year":"2014","journal-title":"J. Med. Chem."},{"key":"D4RA06290F\/cit102\/1","doi-asserted-by":"crossref","first-page":"9673","DOI":"10.1021\/jm501497m","volume":"57","author":"Bozdag","year":"2014","journal-title":"J. Med. Chem."},{"key":"D4RA06290F\/cit103\/1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3109\/14756366.2012.750311","volume":"29","author":"Akbaba","year":"2014","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit104\/1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.ejmech.2014.02.023","volume":"76","author":"Khloya","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit105\/1","doi-asserted-by":"crossref","first-page":"118","DOI":"10.3109\/14756366.2012.757222","volume":"29","author":"Sonmez","year":"2014","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit106\/1","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1016\/j.bmc.2014.01.055","volume":"22","author":"Celik","year":"2014","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit107\/1","first-page":"594879","volume":"1","author":"Kuday","year":"2014","journal-title":"BioMed Res. Int."},{"key":"D4RA06290F\/cit108\/1","doi-asserted-by":"crossref","first-page":"901","DOI":"10.3109\/14756366.2013.866660","volume":"29","author":"Saeed","year":"2014","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit109\/1","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1002\/ardp.201400257","volume":"347","author":"Akbaba","year":"2014","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit110\/1","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1021\/ml500196t","volume":"5","author":"Pala","year":"2014","journal-title":"ACS Med. Chem. Lett."},{"key":"D4RA06290F\/cit111\/1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ejmech.2013.10.081","volume":"71","author":"\u017bo\u0142nowska","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit112\/1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.3109\/21691401.2013.769448","volume":"42","author":"Celik","year":"2014","journal-title":"Artif. Cells, Nanomed., Biotechnol."},{"key":"D4RA06290F\/cit113\/1","doi-asserted-by":"crossref","first-page":"132","DOI":"10.3109\/14756366.2012.757603","volume":"29","author":"Demirci","year":"2014","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit114\/1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/ardp.201300273","volume":"347","author":"Ak\u0131nc\u0131o\u011flu","year":"2014","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit115\/1","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.ejmech.2014.03.023","volume":"78","author":"Zaib","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit116\/1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ejmech.2014.05.039","volume":"82","author":"S\u0142awi\u0144ski","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit117\/1","doi-asserted-by":"crossref","first-page":"33029","DOI":"10.1039\/C4RA03819C","volume":"4","author":"Wang","year":"2014","journal-title":"RSC Adv."},{"key":"D4RA06290F\/cit118\/1","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1021\/ml500140t","volume":"5","author":"Pichake","year":"2014","journal-title":"ACS Med. Chem. Lett."},{"key":"D4RA06290F\/cit119\/1","doi-asserted-by":"crossref","first-page":"3208","DOI":"10.1016\/j.bmcl.2015.05.096","volume":"25","author":"Khloya","year":"2015","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D4RA06290F\/cit120\/1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.bioorg.2015.08.001","volume":"62","author":"Imran","year":"2015","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit121\/1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ejmech.2015.07.049","volume":"102","author":"Buemi","year":"2015","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit122\/1","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.ejmech.2015.09.021","volume":"103","author":"Ibrahim","year":"2015","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit123\/1","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1134\/S1068162015040111","volume":"41","author":"Berber","year":"2015","journal-title":"Russ. J. Bioorg. Chem."},{"key":"D4RA06290F\/cit124\/1","doi-asserted-by":"crossref","first-page":"901","DOI":"10.3109\/14756366.2014.986118","volume":"30","author":"Singasane","year":"2015","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit125\/1","doi-asserted-by":"crossref","first-page":"336","DOI":"10.2174\/1573406410666141203123926","volume":"11","author":"Muhammad Saad","year":"2015","journal-title":"Med. Chem."},{"key":"D4RA06290F\/cit126\/1","doi-asserted-by":"crossref","first-page":"4989","DOI":"10.1016\/j.bmc.2015.05.019","volume":"23","author":"Ibrahim","year":"2015","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit127\/1","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1080\/14756366.2016.1197221","volume":"31","author":"Mishra","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit128\/1","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1002\/ardp.201600183","volume":"349","author":"Aksu","year":"2016","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit129\/1","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.3390\/ijms17101736","volume":"17","author":"Gen\u00e7","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"D4RA06290F\/cit130\/1","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.bioorg.2016.07.006","volume":"68","author":"Mert","year":"2016","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit131\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/14756366.2016.1198901","volume":"31","author":"Garibov","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit132\/1","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.3109\/14756366.2015.1113172","volume":"31","author":"Sujayev","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit133\/1","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1016\/j.bmc.2016.05.016","volume":"24","author":"Gawad","year":"2016","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit134\/1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1080\/14756366.2016.1217852","volume":"31","author":"Kucukoglu","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit135\/1","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.ejmech.2016.01.030","volume":"110","author":"Eldehna","year":"2016","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit136\/1","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.bbrc.2016.11.028","volume":"482","author":"Saeed","year":"2017","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"D4RA06290F\/cit137\/1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.bioorg.2017.03.014","volume":"72","author":"Iqbal","year":"2017","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit138\/1","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1080\/13813455.2017.1332651","volume":"123","author":"G\u00fcle\u00e7","year":"2017","journal-title":"Arch. Physiol. Biochem."},{"key":"D4RA06290F\/cit139\/1","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1080\/14756366.2017.1337759","volume":"32","author":"Bozdag","year":"2017","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit140\/1","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1002\/cmdc.201700446","volume":"12","author":"Angapelly","year":"2017","journal-title":"ChemMedChem"},{"key":"D4RA06290F\/cit141\/1","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1080\/14756366.2017.1380638","volume":"32","author":"Ramya","year":"2017","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit142\/1","doi-asserted-by":"crossref","first-page":"e21998","DOI":"10.1002\/jbt.21998","volume":"31","author":"Altundas","year":"2017","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"D4RA06290F\/cit143\/1","doi-asserted-by":"crossref","first-page":"e21931","DOI":"10.1002\/jbt.21931","volume":"31","author":"Taslimi","year":"2017","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"D4RA06290F\/cit144\/1","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1007\/s00044-017-1865-2","volume":"26","author":"Oktay","year":"2017","journal-title":"Med. Chem. Res."},{"key":"D4RA06290F\/cit145\/1","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1080\/14756366.2017.1354857","volume":"32","author":"Zengin Kurt","year":"2017","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit146\/1","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1080\/14756366.2017.1368019","volume":"32","author":"Gul\u00e7in","year":"2017","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit147\/1","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.molstruc.2017.11.079","volume":"1155","author":"Erdemir","year":"2018","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit148\/1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.molstruc.2018.05.077","volume":"1170","author":"Behcet","year":"2018","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit149\/1","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.bioorg.2017.11.015","volume":"76","author":"Ahmed","year":"2018","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit150\/1","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.ejmech.2017.12.049","volume":"144","author":"Ansari","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit151\/1","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.ejmech.2018.03.030","volume":"150","author":"Vats","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit152\/1","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.ejmech.2018.06.021","volume":"155","author":"Kumar","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit153\/1","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1080\/14756366.2018.1513927","volume":"33","author":"El-Gazzar","year":"2018","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit154\/1","doi-asserted-by":"crossref","first-page":"1800167","DOI":"10.1002\/ardp.201800167","volume":"351","author":"Ekiz","year":"2018","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit155\/1","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.ejmech.2018.07.019","volume":"156","author":"Mishra","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit156\/1","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1002\/ddr.21464","volume":"79","author":"Qamar","year":"2018","journal-title":"Drug Dev. Res."},{"key":"D4RA06290F\/cit157\/1","doi-asserted-by":"crossref","first-page":"103153","DOI":"10.1016\/j.bioorg.2019.103153","volume":"91","author":"Sa\u011fl\u0131k","year":"2019","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit158\/1","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.bioorg.2019.03.052","volume":"87","author":"Alaa","year":"2019","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit159\/1","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.bioorg.2018.11.031","volume":"84","author":"Mahar","year":"2019","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit160\/1","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.bioorg.2019.02.013","volume":"86","author":"Turkan","year":"2019","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit161\/1","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.bioorg.2019.02.004","volume":"86","author":"Thacker","year":"2019","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit162\/1","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.bioorg.2019.03.003","volume":"87","author":"Kurt","year":"2019","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit163\/1","doi-asserted-by":"crossref","first-page":"111702","DOI":"10.1016\/j.ejmech.2019.111702","volume":"183","author":"Kurt","year":"2019","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit164\/1","doi-asserted-by":"crossref","first-page":"103096","DOI":"10.1016\/j.bioorg.2019.103096","volume":"90","author":"Bayindir","year":"2019","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit165\/1","doi-asserted-by":"crossref","first-page":"103102","DOI":"10.1016\/j.bioorg.2019.103102","volume":"90","author":"Eldehna","year":"2019","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit166\/1","doi-asserted-by":"crossref","first-page":"2000102","DOI":"10.1002\/ardp.202000102","volume":"353","author":"I\u015f\u0131k","year":"2020","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit167\/1","doi-asserted-by":"crossref","first-page":"112745","DOI":"10.1016\/j.ejmech.2020.112745","volume":"207","author":"Alkhaldi","year":"2020","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit168\/1","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1016\/j.ijbiomac.2020.09.043","volume":"163","author":"Sever","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"D4RA06290F\/cit169\/1","doi-asserted-by":"crossref","first-page":"1900383","DOI":"10.1002\/ardp.201900383","volume":"353","author":"Istrefi","year":"2020","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit170\/1","doi-asserted-by":"crossref","first-page":"111843","DOI":"10.1016\/j.ejmech.2019.111843","volume":"185","author":"Said","year":"2020","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit171\/1","doi-asserted-by":"crossref","first-page":"598095","DOI":"10.3389\/fchem.2020.598095","volume":"8","author":"Khan","year":"2020","journal-title":"Front. Chem."},{"key":"D4RA06290F\/cit172\/1","doi-asserted-by":"crossref","first-page":"2831","DOI":"10.1002\/jhet.3992","volume":"57","author":"Saeed","year":"2020","journal-title":"J. Heterocycl. Chem."},{"key":"D4RA06290F\/cit173\/1","doi-asserted-by":"crossref","first-page":"103635","DOI":"10.1016\/j.bioorg.2020.103635","volume":"96","author":"George","year":"2020","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit174\/1","doi-asserted-by":"crossref","first-page":"103739","DOI":"10.1016\/j.bioorg.2020.103739","volume":"98","author":"Thacker","year":"2020","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit175\/1","doi-asserted-by":"crossref","first-page":"103514","DOI":"10.1016\/j.bioorg.2019.103514","volume":"95","author":"George","year":"2020","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit176\/1","doi-asserted-by":"crossref","first-page":"104647","DOI":"10.1016\/j.bioorg.2021.104647","volume":"108","author":"Singh","year":"2021","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit177\/1","doi-asserted-by":"crossref","first-page":"128249","DOI":"10.1016\/j.bmcl.2021.128249","volume":"48","author":"Manzoor","year":"2021","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D4RA06290F\/cit178\/1","doi-asserted-by":"crossref","first-page":"127856","DOI":"10.1016\/j.bmcl.2021.127856","volume":"37","author":"Swain","year":"2021","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D4RA06290F\/cit179\/1","doi-asserted-by":"crossref","first-page":"116279","DOI":"10.1016\/j.bmc.2021.116279","volume":"44","author":"Mancuso","year":"2021","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit180\/1","doi-asserted-by":"crossref","first-page":"131145","DOI":"10.1016\/j.molstruc.2021.131145","volume":"1246","author":"Abas","year":"2021","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit181\/1","doi-asserted-by":"crossref","first-page":"113351","DOI":"10.1016\/j.ejmech.2021.113351","volume":"217","author":"Yamali","year":"2021","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit182\/1","doi-asserted-by":"crossref","first-page":"113486","DOI":"10.1016\/j.ejmech.2021.113486","volume":"221","author":"Eldeeb","year":"2021","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit183\/1","doi-asserted-by":"crossref","first-page":"26241","DOI":"10.1039\/D1RA05277B","volume":"11","author":"Nemr","year":"2021","journal-title":"RSC Adv."},{"key":"D4RA06290F\/cit184\/1","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1021\/acsomega.1c05362","volume":"7","author":"Saadiq","year":"2021","journal-title":"ACS Omega"},{"key":"D4RA06290F\/cit185\/1","doi-asserted-by":"crossref","first-page":"113800","DOI":"10.1016\/j.ejmech.2021.113800","volume":"225","author":"Elimam","year":"2021","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit186\/1","doi-asserted-by":"crossref","first-page":"133048","DOI":"10.1016\/j.molstruc.2022.133048","volume":"1262","author":"Zaib","year":"2022","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit187\/1","doi-asserted-by":"crossref","first-page":"128809","DOI":"10.1016\/j.bmcl.2022.128809","volume":"70","author":"Singh","year":"2022","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"D4RA06290F\/cit188\/1","doi-asserted-by":"crossref","first-page":"114004","DOI":"10.1016\/j.ejmech.2021.114004","volume":"228","author":"Abdel-Mohsen","year":"2022","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit189\/1","doi-asserted-by":"crossref","first-page":"105764","DOI":"10.1016\/j.bioorg.2022.105764","volume":"123","author":"Kumar","year":"2022","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit190\/1","doi-asserted-by":"crossref","first-page":"114190","DOI":"10.1016\/j.ejmech.2022.114190","volume":"232","author":"Tawfik","year":"2022","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit191\/1","doi-asserted-by":"crossref","first-page":"8028","DOI":"10.3390\/molecules27228028","volume":"27","author":"Swain","year":"2022","journal-title":"Molecules"},{"key":"D4RA06290F\/cit192\/1","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1080\/14756366.2022.2036137","volume":"37","author":"Said","year":"2022","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit193\/1","doi-asserted-by":"crossref","first-page":"2200232","DOI":"10.1002\/ardp.202200232","volume":"355","author":"Thacker","year":"2022","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit194\/1","doi-asserted-by":"crossref","first-page":"2200180","DOI":"10.1002\/ardp.202200180","volume":"355","author":"Abdel-Mohsen","year":"2022","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit195\/1","doi-asserted-by":"crossref","first-page":"2100405","DOI":"10.1002\/ardp.202100405","volume":"355","author":"Ismail","year":"2022","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit196\/1","doi-asserted-by":"crossref","first-page":"124232","DOI":"10.1016\/j.ijbiomac.2023.124232","volume":"239","author":"Buza","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"D4RA06290F\/cit197\/1","doi-asserted-by":"crossref","first-page":"115180","DOI":"10.1016\/j.ejmech.2023.115180","volume":"250","author":"Ragab","year":"2023","journal-title":"Eur. J. Med. Chem."},{"key":"D4RA06290F\/cit198\/1","doi-asserted-by":"crossref","first-page":"117111","DOI":"10.1016\/j.bmc.2022.117111","volume":"77","author":"Kakakhan","year":"2023","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit199\/1","doi-asserted-by":"crossref","first-page":"101866","DOI":"10.1016\/j.jsps.2023.101866","volume":"31","author":"El-Azab","year":"2023","journal-title":"Saudi Pharm. J."},{"key":"D4RA06290F\/cit200\/1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/bab.2534","volume":"71","author":"\u00d6zt\u00fcrk","year":"2024","journal-title":"Biotechnol. Appl. Biochem."},{"key":"D4RA06290F\/cit201\/1","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1080\/1062936X.2023.2240698","volume":"34","author":"Bostanc\u0131","year":"2023","journal-title":"SAR QSAR Environ. Res."},{"key":"D4RA06290F\/cit202\/1","doi-asserted-by":"crossref","first-page":"5571","DOI":"10.1021\/acsomega.2c06954","volume":"8","author":"Metwally","year":"2023","journal-title":"ACS Omega"},{"key":"D4RA06290F\/cit203\/1","doi-asserted-by":"crossref","first-page":"2270180","DOI":"10.1080\/14756366.2023.2270180","volume":"38","author":"Romagnoli","year":"2023","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"D4RA06290F\/cit204\/1","doi-asserted-by":"crossref","first-page":"e202301641","DOI":"10.1002\/slct.202301641","volume":"8","author":"\u00dcnver","year":"2023","journal-title":"ChemistrySelect"},{"key":"D4RA06290F\/cit205\/1","doi-asserted-by":"crossref","first-page":"e14351","DOI":"10.1111\/cbdd.14351","volume":"103","author":"\u00c7elik","year":"2024","journal-title":"Chem. Biol. Drug Des."},{"key":"D4RA06290F\/cit206\/1","doi-asserted-by":"crossref","first-page":"134699","DOI":"10.1016\/j.molstruc.2022.134699","volume":"1276","author":"Kucukoglu","year":"2023","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit207\/1","doi-asserted-by":"crossref","first-page":"117467","DOI":"10.1016\/j.bmc.2023.117467","volume":"94","author":"Begines","year":"2023","journal-title":"Bioorg. Med. Chem."},{"key":"D4RA06290F\/cit208\/1","doi-asserted-by":"crossref","first-page":"134767","DOI":"10.1016\/j.molstruc.2022.134767","volume":"1276","author":"Zahedi","year":"2023","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit209\/1","doi-asserted-by":"crossref","first-page":"106621","DOI":"10.1016\/j.bioorg.2023.106621","volume":"138","author":"Angeli","year":"2023","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit210\/1","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1002\/ddr.22049","volume":"84","author":"Huwaimel","year":"2023","journal-title":"Drug Dev. Res."},{"key":"D4RA06290F\/cit211\/1","doi-asserted-by":"crossref","first-page":"136609","DOI":"10.1016\/j.molstruc.2023.136609","volume":"1295","author":"Alalawy","year":"2024","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit212\/1","doi-asserted-by":"crossref","first-page":"137277","DOI":"10.1016\/j.molstruc.2023.137277","volume":"1300","author":"Takla","year":"2024","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit213\/1","doi-asserted-by":"crossref","first-page":"136770","DOI":"10.1016\/j.molstruc.2023.136770","volume":"1295","author":"\u00c7evik","year":"2024","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit214\/1","doi-asserted-by":"crossref","first-page":"137365","DOI":"10.1016\/j.molstruc.2023.137365","volume":"1301","author":"Efeoglu","year":"2024","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit215\/1","first-page":"139472","author":"Mert","year":"2024","journal-title":"J. Mol. Struct."},{"key":"D4RA06290F\/cit216\/1","doi-asserted-by":"crossref","first-page":"131548","DOI":"10.1016\/j.ijbiomac.2024.131548","volume":"268","author":"Singh","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D4RA06290F\/cit217\/1","doi-asserted-by":"crossref","first-page":"107154","DOI":"10.1016\/j.bioorg.2024.107154","volume":"144","author":"Abdelhakeem","year":"2024","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit218\/1","doi-asserted-by":"crossref","first-page":"107089","DOI":"10.1016\/j.bioorg.2023.107089","volume":"144","author":"Higazy","year":"2024","journal-title":"Bioorg. Chem."},{"key":"D4RA06290F\/cit219\/1","doi-asserted-by":"crossref","first-page":"3018","DOI":"10.1021\/acs.jmedchem.3c02190","volume":"67","author":"Al-Matarneh","year":"2024","journal-title":"J. Med. Chem."},{"key":"D4RA06290F\/cit220\/1","doi-asserted-by":"crossref","first-page":"e2400064","DOI":"10.1002\/ardp.202400064","author":"Maddipatla","year":"2024","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit221\/1","doi-asserted-by":"crossref","first-page":"e2400038","DOI":"10.1002\/ardp.202400038","author":"Sobati","year":"2024","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit222\/1","doi-asserted-by":"crossref","first-page":"2300718","DOI":"10.1002\/ardp.202300718","volume":"357","author":"Swain","year":"2024","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit223\/1","doi-asserted-by":"crossref","first-page":"2300545","DOI":"10.1002\/ardp.202300545","volume":"357","author":"El Ati","year":"2024","journal-title":"Arch. Pharm."},{"key":"D4RA06290F\/cit224\/1","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1021\/acsmedchemlett.3c00484","volume":"15","author":"Moi","year":"2024","journal-title":"ACS Med. Chem. Lett."},{"key":"D4RA06290F\/cit225\/1","doi-asserted-by":"crossref","first-page":"e23704","DOI":"10.1002\/jbt.23704","volume":"38","author":"\u00d6zkul","year":"2024","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"D4RA06290F\/cit226\/1","doi-asserted-by":"crossref","first-page":"6532","DOI":"10.1039\/D4OB00826J","author":"Palomba","year":"2024","journal-title":"Org. Biomol. Chem."},{"key":"D4RA06290F\/cit227\/1","doi-asserted-by":"crossref","first-page":"e202301824","DOI":"10.1002\/cbdv.202301824","volume":"21","author":"Durgun","year":"2024","journal-title":"Chem. Biodiversity"},{"key":"D4RA06290F\/cit228\/1","doi-asserted-by":"crossref","first-page":"e202400147","DOI":"10.1002\/cmdc.202400147","author":"Angeli","year":"2024","journal-title":"ChemMedChem"},{"key":"D4RA06290F\/cit229\/1","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1039\/D4MD00101J","author":"Aslan","year":"2024","journal-title":"RSC Med. Chem."},{"key":"D4RA06290F\/cit230\/1","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1039\/D4MD00302K","volume":"15","author":"Albelwi","year":"2024","journal-title":"RSC Med. Chem."},{"key":"D4RA06290F\/cit231\/1","first-page":"1","author":"Yetek","year":"2024","journal-title":"Mol. Diversity"},{"key":"D4RA06290F\/cit232\/1","doi-asserted-by":"crossref","first-page":"603","DOI":"10.2174\/138161208783877884","volume":"14","author":"Supuran","year":"2008","journal-title":"Curr. Pharm. Des."},{"key":"D4RA06290F\/cit233\/1","doi-asserted-by":"crossref","first-page":"4421","DOI":"10.1021\/cr200176r","volume":"112","author":"Alterio","year":"2012","journal-title":"Chem. Rev."},{"key":"D4RA06290F\/cit234\/1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1021\/jm901287j","volume":"53","author":"Maresca","year":"2010","journal-title":"J. Med. Chem."},{"key":"D4RA06290F\/cit235\/1","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0960-894X(03)00091-X","volume":"13","author":"Vullo","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2024\/RA\/D4RA06290F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T03:59:13Z","timestamp":1782964753000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ra\/article\/14\/48\/35769-35970\/867352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":235,"journal-issue":{"issue":"48","published-print":{"date-parts":[[2024,11,4]]}},"URL":"https:\/\/doi.org\/10.1039\/d4ra06290f","relation":{},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}