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Sci."],"abstract":"<jats:p>\n                    The concise total synthesis of ngouniensines is reported, in which 2-Me-tryptamine undergoes sequential C\u2013H functionalization with different aldehydes to afford the azepino[4,5-\n                    <jats:italic>b<\/jats:italic>\n                    ]indole core and an exocyclic conjugated alkene, respectively.\n                  <\/jats:p>","DOI":"10.1039\/d4sc02802c","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T12:21:08Z","timestamp":1720182068000},"page":"12732-12738","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["C\u2013H functionalization of 2-alkyl tryptamines: direct assembly of azepino[4,5-\n                    <i>b<\/i>\n                    ]indoles and total synthesis of ngouniensines"],"prefix":"10.1039","volume":"15","author":[{"given":"Kejing","family":"Xie","sequence":"first","affiliation":[{"name":"School of Pharmaceutical Sciences, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Beijing Frontier Research Center for Biological Structure, Tsinghua University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeyuan","family":"Shen","sequence":"additional","affiliation":[{"name":"Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Beijing Frontier Research Center for Biological Structure, Tsinghua University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoxiang","family":"Dong","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Beijing Frontier Research Center for Biological Structure, Tsinghua University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0939-9727","authenticated-orcid":false,"given":"Zhi-Xiang","family":"Yu","sequence":"additional","affiliation":[{"name":"Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7747-2979","authenticated-orcid":false,"given":"Liansuo","family":"Zu","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Beijing Frontier Research Center for Biological Structure, Tsinghua University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2024]]},"reference":[{"key":"D4SC02802C\/cit1\/1","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1021\/cr00038a004","volume":"95","author":"Cox","year":"1995","journal-title":"Chem. 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