{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T21:50:20Z","timestamp":1782856220512,"version":"3.54.5"},"reference-count":41,"publisher":"Royal Society of Chemistry (RSC)","issue":"9","license":[{"start":{"date-parts":[[2027,3,23]],"date-time":"2027-03-23T00:00:00Z","timestamp":1805760000000},"content-version":"am","delay-in-days":446,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62375121"],"award-info":[{"award-number":["62375121"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Analyst"],"abstract":"<jats:p>An optical microfluidic chip integrating a functionalized hollow-core fiber achieves rapid and highly sensitive detection of influenza A virus through waveguide-confined fluorescence excitation enhancement and efficient collection.<\/jats:p>","DOI":"10.1039\/d5an01308a","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T09:37:52Z","timestamp":1774258672000},"page":"2602-2612","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A hollow-core fiber based optofluidic chip for rapid immunofluorescence detection with simultaneous enhancement of sensitivity and enrichment efficiency"],"prefix":"10.1039","volume":"151","author":[{"given":"Xiao","family":"Ren","sequence":"first","affiliation":[{"name":"College of Engineering and Applied Sciences, Nanjing University, Nanjing, 210093, PR China"},{"name":"Key Laboratory of Intelligent Optical Sensing and Integration of the Ministry of Education, Nanjing University, Nanjing, 210009, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6566-8659","authenticated-orcid":false,"given":"Tian","family":"Wen","sequence":"additional","affiliation":[{"name":"Jiangsu Provincial Center for Disease Control and Prevention, NHC Key Laboratory of Enteric Pathogenic Microbiology, Nanjing, Jiangsu Province, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2427-6290","authenticated-orcid":false,"given":"Yukai","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Engineering and Applied Sciences, Nanjing University, Nanjing, 210093, PR China"},{"name":"Key Laboratory of Intelligent Optical Sensing and Integration of the Ministry of Education, Nanjing University, Nanjing, 210009, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxian","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Anhui Agricultural University, Hefei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Lin","sequence":"additional","affiliation":[{"name":"College of Engineering and Applied Sciences, Nanjing University, Nanjing, 210093, PR China"},{"name":"Key Laboratory of Intelligent Optical Sensing and Integration of the Ministry of Education, Nanjing University, Nanjing, 210009, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyong","family":"Dong","sequence":"additional","affiliation":[{"name":"College of Engineering and Applied Sciences, Nanjing University, Nanjing, 210093, PR China"},{"name":"Key Laboratory of Intelligent Optical Sensing and Integration of the Ministry of Education, Nanjing University, Nanjing, 210009, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Engineering and Applied Sciences, Nanjing University, Nanjing, 210093, PR China"},{"name":"Key Laboratory of Intelligent Optical Sensing and Integration of the Ministry of Education, Nanjing University, Nanjing, 210009, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lunbiao","family":"Cui","sequence":"additional","affiliation":[{"name":"Jiangsu Provincial Center for Disease Control and Prevention, NHC Key Laboratory of Enteric Pathogenic Microbiology, Nanjing, Jiangsu Province, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-qing","family":"Lu","sequence":"additional","affiliation":[{"name":"College of Engineering and Applied Sciences, Nanjing University, Nanjing, 210093, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6832-7937","authenticated-orcid":false,"given":"Guanghui","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Engineering and Applied Sciences, Nanjing University, Nanjing, 210093, PR China"},{"name":"Key Laboratory of Intelligent Optical Sensing and Integration of the Ministry of Education, Nanjing University, Nanjing, 210009, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D5AN01308A\/cit1\/1","doi-asserted-by":"crossref","first-page":"4640","DOI":"10.1038\/srep04640","volume":"4","author":"Abe","year":"2014","journal-title":"Sci. Rep."},{"key":"D5AN01308A\/cit2\/1","doi-asserted-by":"crossref","first-page":"17386","DOI":"10.1021\/ja205925j","volume":"133","author":"Abe","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"D5AN01308A\/cit3\/1","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.3390\/s21041223","volume":"21","author":"Dong","year":"2021","journal-title":"Sensors"},{"key":"D5AN01308A\/cit4\/1","doi-asserted-by":"crossref","first-page":"153449","DOI":"10.1016\/j.bbrc.2026.153449","volume":"808","author":"Fukunaga","year":"2026","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"D5AN01308A\/cit5\/1","doi-asserted-by":"crossref","first-page":"5079","DOI":"10.1039\/C7TB01049D","volume":"5","author":"Gong","year":"2017","journal-title":"J. Mater. Chem. B"},{"key":"D5AN01308A\/cit6\/1","first-page":"458","author":"Kohl","year":"2017","journal-title":"Cold Spring Harb. Protoc."},{"key":"D5AN01308A\/cit7\/1","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.3390\/ijms23031426","volume":"23","author":"Pina","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"D5AN01308A\/cit8\/1","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1039\/D2AN01913B","volume":"148","author":"Rani","year":"2023","journal-title":"Analyst"},{"key":"D5AN01308A\/cit9\/1","doi-asserted-by":"crossref","first-page":"3086","DOI":"10.3390\/ijms24043086","volume":"24","author":"Sheng","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"D5AN01308A\/cit10\/1","doi-asserted-by":"crossref","first-page":"3457","DOI":"10.1021\/acssensors.0c01404","volume":"5","author":"Inoue","year":"2020","journal-title":"ACS Sens."},{"key":"D5AN01308A\/cit11\/1","doi-asserted-by":"crossref","first-page":"12321","DOI":"10.1021\/acs.analchem.3c01696","volume":"95","author":"Liang","year":"2023","journal-title":"Anal. Chem."},{"key":"D5AN01308A\/cit12\/1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.cplett.2018.03.011","volume":"698","author":"Mori","year":"2018","journal-title":"Chem. Phys. Lett."},{"key":"D5AN01308A\/cit13\/1","first-page":"C112","volume":"76","author":"Lumor","year":"2011","journal-title":"J. Food Sci."},{"key":"D5AN01308A\/cit14\/1","first-page":"366","author":"Yin","year":"2022","journal-title":"Sens. Actuators, B"},{"key":"D5AN01308A\/cit15\/1","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1080\/00032719.2023.2287585","volume":"57","author":"Cao","year":"2023","journal-title":"Anal. Lett."},{"key":"D5AN01308A\/cit16\/1","doi-asserted-by":"crossref","first-page":"134698","DOI":"10.1016\/j.foodchem.2022.134698","volume":"404","author":"Cheng","year":"2023","journal-title":"Food Chem."},{"key":"D5AN01308A\/cit17\/1","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.bios.2013.04.048","volume":"49","author":"Fu","year":"2013","journal-title":"Biosens. Bioelectron."},{"key":"D5AN01308A\/cit18\/1","doi-asserted-by":"crossref","first-page":"141916","DOI":"10.1016\/j.foodchem.2024.141916","volume":"464","author":"Li","year":"2025","journal-title":"Food Chem."},{"key":"D5AN01308A\/cit19\/1","doi-asserted-by":"crossref","first-page":"1628008","DOI":"10.1155\/2024\/1628008","volume":"2024","author":"Yang","year":"2024","journal-title":"Transboundary Emerging Dis."},{"key":"D5AN01308A\/cit20\/1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.bios.2019.04.023","volume":"135","author":"Zhang","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"D5AN01308A\/cit21\/1","first-page":"26","author":"Chen","year":"2022","journal-title":"Microfluid. Nanofluid."},{"key":"D5AN01308A\/cit22\/1","doi-asserted-by":"crossref","first-page":"113527","DOI":"10.1016\/j.bios.2021.113527","volume":"193","author":"Chen","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"D5AN01308A\/cit23\/1","doi-asserted-by":"crossref","first-page":"e2005179","DOI":"10.1002\/smll.202005179","volume":"16","author":"Hao","year":"2020","journal-title":"Small"},{"key":"D5AN01308A\/cit24\/1","doi-asserted-by":"crossref","first-page":"18176","DOI":"10.1021\/acs.langmuir.3c03890","volume":"40","author":"Yabu","year":"2024","journal-title":"Langmuir"},{"key":"D5AN01308A\/cit25\/1","doi-asserted-by":"crossref","first-page":"2645","DOI":"10.1021\/ac302903p","volume":"85","author":"Zhang","year":"2013","journal-title":"Anal. Chem."},{"key":"D5AN01308A\/cit26\/1","doi-asserted-by":"crossref","first-page":"055502","DOI":"10.1088\/1361-6501\/add034","volume":"36","author":"Kumari","year":"2025","journal-title":"Meas. Sci. Technol."},{"key":"D5AN01308A\/cit27\/1","doi-asserted-by":"crossref","first-page":"5716","DOI":"10.1364\/AO.426762","volume":"60","author":"Li","year":"2021","journal-title":"Appl. Opt."},{"key":"D5AN01308A\/cit28\/1","first-page":"1095","volume":"95","author":"Liu","year":"2023","journal-title":"Anal. Chem."},{"key":"D5AN01308A\/cit29\/1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s10544-008-9227-y","volume":"11","author":"Ramasubramanian","year":"2009","journal-title":"Biomed. Microdevices"},{"key":"D5AN01308A\/cit30\/1","doi-asserted-by":"crossref","first-page":"25662","DOI":"10.1364\/OE.496833","volume":"31","author":"Tan","year":"2023","journal-title":"Opt. Express"},{"key":"D5AN01308A\/cit31\/1","doi-asserted-by":"crossref","first-page":"4501","DOI":"10.1039\/D2LC00681B","volume":"22","author":"Wei","year":"2022","journal-title":"Lab Chip"},{"key":"D5AN01308A\/cit32\/1","doi-asserted-by":"crossref","first-page":"22752","DOI":"10.1109\/JSEN.2021.3107721","volume":"21","author":"Wu","year":"2021","journal-title":"IEEE Sens. J."},{"key":"D5AN01308A\/cit33\/1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jes.2023.05.013","volume":"146","author":"Feng","year":"2024","journal-title":"J. Environ. Sci."},{"key":"D5AN01308A\/cit34\/1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s11671-018-2487-4","volume":"13","author":"Xiao","year":"2018","journal-title":"Nanoscale Res. Lett."},{"key":"D5AN01308A\/cit35\/1","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.3390\/mi12121592","volume":"12","author":"Chen","year":"2021","journal-title":"Micromachines"},{"key":"D5AN01308A\/cit36\/1","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1016\/j.bpj.2017.02.042","volume":"112","author":"Ciocanel","year":"2017","journal-title":"Biophys. J."},{"key":"D5AN01308A\/cit37\/1","doi-asserted-by":"crossref","first-page":"102439","DOI":"10.1016\/j.cbpa.2024.102439","volume":"79","author":"Zhang","year":"2024","journal-title":"Curr. Opin. Chem. Biol."},{"key":"D5AN01308A\/cit38\/1","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1039\/C8LC01369A","volume":"19","author":"Shen","year":"2019","journal-title":"Lab Chip"},{"key":"D5AN01308A\/cit39\/1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.talanta.2018.09.049","volume":"192","author":"Kyme","year":"2019","journal-title":"Talanta"},{"key":"D5AN01308A\/cit40\/1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.3390\/bios14060263","volume":"14","author":"Chen","year":"2024","journal-title":"Biosensors"},{"key":"D5AN01308A\/cit41\/1","doi-asserted-by":"crossref","first-page":"4582","DOI":"10.1039\/D4AY00847B","volume":"16","author":"Liu","year":"2024","journal-title":"Anal. Methods"}],"container-title":["The Analyst"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2026\/AN\/D5AN01308A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T20:40:50Z","timestamp":1782852050000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/an\/article\/151\/9\/2602-2612\/1229917"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":41,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,5,5]]}},"URL":"https:\/\/doi.org\/10.1039\/d5an01308a","relation":{},"ISSN":["0003-2654","1364-5528"],"issn-type":[{"value":"0003-2654","type":"print"},{"value":"1364-5528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}