{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T14:46:19Z","timestamp":1788273979320,"version":"build-2803163510"},"reference-count":37,"publisher":"Royal Society of Chemistry (RSC)","issue":"21","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"am","delay-in-days":624,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515012091"],"award-info":[{"award-number":["2024A1515012091"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFB3808300"],"award-info":[{"award-number":["2022YFB3808300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2024ZYGXZR022"],"award-info":[{"award-number":["2024ZYGXZR022"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Biomater. Sci."],"abstract":"<jats:p>We developed a supramolecular hydrogel-based single-cell encapsulation strategy that mimics the dynamic ECM microenvironment, enhancing MSC energy metabolism, stress resistance, and regenerative capacity, thereby improving cardiac repair.<\/jats:p>","DOI":"10.1039\/d5bm01013f","type":"journal-article","created":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T07:21:03Z","timestamp":1758093663000},"page":"6127-6137","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Single-cell encapsulation of mesenchymal stromal cells\n                    <i>via<\/i>\n                    ECM-mimetic supramolecular hydrogels enhances therapeutic efficacy"],"prefix":"10.1039","volume":"13","author":[{"given":"Xueting","family":"Wei","sequence":"first","affiliation":[{"name":"School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 511442, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajia","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 511442, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianghua","family":"Zhong","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 511442, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuebing","family":"Tao","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 511442, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyang","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 511442, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Peng","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 511442, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2481-4781","authenticated-orcid":false,"given":"Kunyu","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 511442, PR China"},{"name":"National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, PR China"},{"name":"Guangdong Provincial Key Laboratory of Biomedical Engineering, South China University of Technology, Guangzhou 510006, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8400-2358","authenticated-orcid":false,"given":"Peng","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 511442, PR China"},{"name":"National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, PR China"},{"name":"Guangdong Provincial Key Laboratory of Biomedical Engineering, South China University of Technology, Guangzhou 510006, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D5BM01013F\/cit1\/1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/s41392-024-01936-8","volume":"9","author":"Shan","year":"2024","journal-title":"Signal Transduct. Target. Ther."},{"key":"D5BM01013F\/cit2\/1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.semcancer.2019.06.003","volume":"60","author":"Timaner","year":"2020","journal-title":"Semin. Cancer Biol."},{"key":"D5BM01013F\/cit3\/1","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/s41392-022-00932-0","volume":"7","author":"Han","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"key":"D5BM01013F\/cit4\/1","doi-asserted-by":"crossref","first-page":"2309719","DOI":"10.1002\/adma.202309719","volume":"36","author":"Wu","year":"2023","journal-title":"Adv. Mater."},{"key":"D5BM01013F\/cit5\/1","doi-asserted-by":"crossref","first-page":"11412","DOI":"10.1021\/acsnano.5c00820","volume":"19","author":"Zhong","year":"2025","journal-title":"ACS Nano"},{"key":"D5BM01013F\/cit6\/1","doi-asserted-by":"crossref","first-page":"2416020","DOI":"10.1002\/adma.202416020","volume":"37","author":"Wu","year":"2025","journal-title":"Adv. Mater."},{"key":"D5BM01013F\/cit7\/1","doi-asserted-by":"crossref","first-page":"115010","DOI":"10.1016\/j.addr.2023.115010","volume":"201","author":"Gupta","year":"2023","journal-title":"Adv. Drug Delivery Rev."},{"key":"D5BM01013F\/cit8\/1","doi-asserted-by":"crossref","first-page":"2001689","DOI":"10.1002\/adhm.202001689","volume":"10","author":"Chang","year":"2021","journal-title":"Adv. Healthcare Mater."},{"key":"D5BM01013F\/cit9\/1","doi-asserted-by":"crossref","first-page":"e70057","DOI":"10.1002\/jev2.70057","volume":"14","author":"Garcia-Aponte","year":"2025","journal-title":"J. Extracell. Vesicles"},{"key":"D5BM01013F\/cit10\/1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/nmeth.3839","volume":"13","author":"Caliari","year":"2016","journal-title":"Nat. Methods"},{"key":"D5BM01013F\/cit11\/1","doi-asserted-by":"crossref","first-page":"16290","DOI":"10.1039\/D4NR02088J","volume":"16","author":"Rijns","year":"2024","journal-title":"Nanoscale"},{"key":"D5BM01013F\/cit12\/1","doi-asserted-by":"crossref","first-page":"17131","DOI":"10.1021\/acsnano.3c04816","volume":"17","author":"Yang","year":"2023","journal-title":"ACS Nano"},{"key":"D5BM01013F\/cit13\/1","doi-asserted-by":"crossref","first-page":"2008111","DOI":"10.1002\/adma.202008111","volume":"33","author":"Diba","year":"2021","journal-title":"Adv. Mater."},{"key":"D5BM01013F\/cit14\/1","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1039\/C2CS35218D","volume":"42","author":"Lindoy","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"D5BM01013F\/cit15\/1","doi-asserted-by":"crossref","first-page":"4855","DOI":"10.1021\/acsbiomaterials.2c01547","volume":"9","author":"Li","year":"2023","journal-title":"ACS Biomater. Sci. Eng."},{"key":"D5BM01013F\/cit16\/1","doi-asserted-by":"crossref","first-page":"2300670","DOI":"10.1002\/advs.202300670","volume":"10","author":"Shou","year":"2023","journal-title":"Adv. Sci."},{"key":"D5BM01013F\/cit17\/1","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.jcyt.2013.09.004","volume":"16","author":"Zimmermann","year":"2014","journal-title":"Cytotherapy"},{"key":"D5BM01013F\/cit18\/1","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1089\/ten.tea.2015.0289","volume":"22","author":"Hong","year":"2016","journal-title":"Tissue Eng., Part A"},{"key":"D5BM01013F\/cit19\/1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1021\/acs.chemrev.4c00984","volume":"125","author":"Rheem","year":"2025","journal-title":"Chem. Rev."},{"key":"D5BM01013F\/cit20\/1","doi-asserted-by":"crossref","first-page":"2300332","DOI":"10.1002\/smsc.202300332","volume":"4","author":"Pires-Santos","year":"2024","journal-title":"Small Sci."},{"key":"D5BM01013F\/cit21\/1","doi-asserted-by":"crossref","first-page":"2100347","DOI":"10.1002\/adhm.202100347","volume":"10","author":"Lee","year":"2021","journal-title":"Adv. Healthcare Mater."},{"key":"D5BM01013F\/cit22\/1","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.tibtech.2018.03.001","volume":"36","author":"Kamperman","year":"2018","journal-title":"Trends Biotechnol."},{"key":"D5BM01013F\/cit23\/1","doi-asserted-by":"crossref","first-page":"26983","DOI":"10.1021\/jacs.3c10295","volume":"145","author":"Huang","year":"2023","journal-title":"J. Am. Chem. Soc."},{"key":"D5BM01013F\/cit24\/1","doi-asserted-by":"crossref","first-page":"8885","DOI":"10.1039\/D2SC02797F","volume":"13","author":"Huang","year":"2022","journal-title":"Chem. Sci."},{"key":"D5BM01013F\/cit25\/1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/s41578-019-0148-6","volume":"5","author":"Daly","year":"2019","journal-title":"Nat. Rev. Mater."},{"issue":"8","key":"D5BM01013F\/cit26\/1","doi-asserted-by":"crossref","first-page":"2302713","DOI":"10.1002\/adhm.202302713","volume":"13","author":"Borges","year":"2024","journal-title":"Adv. Healthcare Mater."},{"issue":"12","key":"D5BM01013F\/cit27\/1","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1002\/asia.201600145","volume":"11","author":"Oliveira","year":"2016","journal-title":"Chem. \u2013 Asian J."},{"key":"D5BM01013F\/cit28\/1","doi-asserted-by":"crossref","first-page":"100323","DOI":"10.1016\/j.giant.2024.100323","volume":"19","author":"Chen","year":"2024","journal-title":"Giant"},{"key":"D5BM01013F\/cit29\/1","doi-asserted-by":"crossref","first-page":"100892","DOI":"10.1016\/j.apmt.2020.100892","volume":"22","author":"Jing","year":"2021","journal-title":"Appl. Mater. Today"},{"key":"D5BM01013F\/cit30\/1","doi-asserted-by":"crossref","first-page":"3514","DOI":"10.1038\/s41467-021-23120-0","volume":"12","author":"Yang","year":"2021","journal-title":"Nat. Commun."},{"key":"D5BM01013F\/cit31\/1","doi-asserted-by":"crossref","first-page":"11298","DOI":"10.1073\/pnas.0703723104","volume":"104","author":"Gerecht","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D5BM01013F\/cit32\/1","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.actbio.2024.01.015","volume":"177","author":"Zhong","year":"2024","journal-title":"Acta Biomater."},{"key":"D5BM01013F\/cit33\/1","doi-asserted-by":"crossref","first-page":"e202319907","DOI":"10.1002\/anie.202319907","volume":"63","author":"Wei","year":"2024","journal-title":"Angew. Chem., Int. Ed."},{"key":"D5BM01013F\/cit34\/1","doi-asserted-by":"crossref","first-page":"4589","DOI":"10.1021\/acsnano.9b00587","volume":"13","author":"Wang","year":"2019","journal-title":"ACS Nano"},{"key":"D5BM01013F\/cit35\/1","doi-asserted-by":"crossref","first-page":"2307176","DOI":"10.1002\/adma.202307176","volume":"36","author":"Li","year":"2024","journal-title":"Adv. Mater."},{"key":"D5BM01013F\/cit36\/1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/s41467-019-13668-3","volume":"11","author":"Martinez-Reyes","year":"2020","journal-title":"Nat. Commun."},{"key":"D5BM01013F\/cit37\/1","doi-asserted-by":"crossref","first-page":"2103697","DOI":"10.1002\/advs.202103697","volume":"9","author":"Yan","year":"2022","journal-title":"Adv. Sci."}],"container-title":["Biomaterials Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/BM\/D5BM01013F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:48:10Z","timestamp":1782884890000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/bm\/article\/13\/21\/6127-6137\/881436"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":37,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2025,10,21]]}},"URL":"https:\/\/doi.org\/10.1039\/d5bm01013f","relation":{},"ISSN":["2047-4830","2047-4849"],"issn-type":[{"value":"2047-4830","type":"print"},{"value":"2047-4849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}