{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T17:39:30Z","timestamp":1793036370254,"version":"4.5.0"},"reference-count":20,"publisher":"Royal Society of Chemistry (RSC)","issue":"9","license":[{"start":{"date-parts":[[2027,3,26]],"date-time":"2027-03-26T00:00:00Z","timestamp":1806019200000},"content-version":"am","delay-in-days":449,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100012165","name":"Key Technologies Research and Development Program","doi-asserted-by":"publisher","award":["2025YFE0114200"],"award-info":[{"award-number":["2025YFE0114200"]}],"id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U24A20477"],"award-info":[{"award-number":["U24A20477"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32571686"],"award-info":[{"award-number":["32571686"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004032","name":"Jilin University","doi-asserted-by":"publisher","award":["2022JBGS04"],"award-info":[{"award-number":["2022JBGS04"]}],"id":[{"id":"10.13039\/501100004032","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011789","name":"Department of Science and Technology of Jilin Province","doi-asserted-by":"publisher","award":["20240501003GH"],"award-info":[{"award-number":["20240501003GH"]}],"id":[{"id":"10.13039\/501100011789","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011789","name":"Department of Science and Technology of Jilin Province","doi-asserted-by":"publisher","award":["YDZJ202102CXJD020"],"award-info":[{"award-number":["YDZJ202102CXJD020"]}],"id":[{"id":"10.13039\/501100011789","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015800","name":"Jilin Province Development and Reform Commission","doi-asserted-by":"publisher","award":["2021C023"],"award-info":[{"award-number":["2021C023"]}],"id":[{"id":"10.13039\/100015800","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017701","name":"Henan Technical Innovation Guidance Projects","doi-asserted-by":"publisher","award":["2024001"],"award-info":[{"award-number":["2024001"]}],"id":[{"id":"10.13039\/501100017701","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Biomater. Sci."],"abstract":"<jats:p>ROS-responsive mPEG-PCL co-delivers PTX-PBE and R848 for immune synergy.<\/jats:p>","DOI":"10.1039\/d5bm01811k","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T03:00:58Z","timestamp":1774494058000},"page":"2463-2471","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["ROS-responsive mPEG-PCL nanoparticles for co-delivery of paclitaxel prodrug and R848 in synergistic chemo-immunotherapy"],"prefix":"10.1039","volume":"14","author":[{"given":"Qi","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Radiotherapy, The Second Hospital of Jilin University, Changchun, Jilin, 130041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luyao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaofan","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, School of Materials Science and Engineering, Peking University, Beijing, 100871, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5623-7224","authenticated-orcid":false,"given":"Shixian","family":"Lv","sequence":"additional","affiliation":[{"name":"Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, School of Materials Science and Engineering, Peking University, Beijing, 100871, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linlin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D5BM01811K\/cit1\/1","first-page":"102","volume":"45","author":"Jin","year":"2025","journal-title":"Bioact. Mater."},{"key":"D5BM01811K\/cit2\/1","first-page":"77","volume":"56","author":"Lin","year":"2026","journal-title":"Bioact. Mater."},{"issue":"11","key":"D5BM01811K\/cit3\/1","doi-asserted-by":"crossref","first-page":"2310456","DOI":"10.1002\/adma.202310456","volume":"36","author":"Yu","year":"2023","journal-title":"Adv. Mater."},{"key":"D5BM01811K\/cit4\/1","doi-asserted-by":"crossref","first-page":"123032","DOI":"10.1016\/j.biomaterials.2024.123032","volume":"316","author":"Zhang","year":"2025","journal-title":"Biomaterials"},{"issue":"52","key":"D5BM01811K\/cit5\/1","doi-asserted-by":"crossref","first-page":"e202214992","DOI":"10.1002\/anie.202214992","volume":"61","author":"Hao","year":"2022","journal-title":"Angew. Chem., Int. Ed."},{"issue":"16","key":"D5BM01811K\/cit6\/1","doi-asserted-by":"crossref","first-page":"eadg2239","DOI":"10.1126\/sciadv.adg2239","volume":"9","author":"Bhagchandani","year":"2023","journal-title":"Sci. Adv."},{"issue":"29","key":"D5BM01811K\/cit7\/1","doi-asserted-by":"crossref","first-page":"2207733","DOI":"10.1002\/adma.202207733","volume":"35","author":"Sun","year":"2023","journal-title":"Adv. Mater."},{"issue":"33","key":"D5BM01811K\/cit8\/1","doi-asserted-by":"crossref","first-page":"10114","DOI":"10.1021\/acs.nanolett.4c02196","volume":"24","author":"Chen","year":"2024","journal-title":"Nano Lett."},{"issue":"1","key":"D5BM01811K\/cit9\/1","doi-asserted-by":"crossref","first-page":"8586","DOI":"10.1038\/s41467-024-53010-0","volume":"15","author":"Guo","year":"2024","journal-title":"Nat. Commun."},{"issue":"23","key":"D5BM01811K\/cit10\/1","doi-asserted-by":"crossref","first-page":"2312493","DOI":"10.1002\/adma.202312493","volume":"36","author":"Xu","year":"2024","journal-title":"Adv. Mater."},{"key":"D5BM01811K\/cit11\/1","doi-asserted-by":"crossref","first-page":"113628","DOI":"10.1016\/j.jconrel.2025.113628","volume":"382","author":"Zhou","year":"2025","journal-title":"J. Controlled Release"},{"issue":"9","key":"D5BM01811K\/cit12\/1","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.1021\/acs.nanolett.4c05863","volume":"25","author":"Zhou","year":"2025","journal-title":"Nano Lett."},{"key":"D5BM01811K\/cit13\/1","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.jconrel.2022.10.053","volume":"352","author":"Liu","year":"2022","journal-title":"J. Controlled Release"},{"issue":"4","key":"D5BM01811K\/cit14\/1","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1021\/jacs.7b12776","volume":"140","author":"Lv","year":"2018","journal-title":"J. Am. Chem. Soc."},{"issue":"7","key":"D5BM01811K\/cit15\/1","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1039\/D3BM01451G","volume":"12","author":"Li","year":"2024","journal-title":"Biomater. Sci."},{"key":"D5BM01811K\/cit16\/1","doi-asserted-by":"crossref","first-page":"114363","DOI":"10.1016\/j.jconrel.2025.114363","volume":"389","author":"Li","year":"2026","journal-title":"J. Controlled Release"},{"issue":"17","key":"D5BM01811K\/cit17\/1","doi-asserted-by":"crossref","first-page":"4335","DOI":"10.1039\/D4BM00647J","volume":"12","author":"Vasvani","year":"2024","journal-title":"Biomater. Sci."},{"key":"D5BM01811K\/cit18\/1","doi-asserted-by":"crossref","first-page":"164599","DOI":"10.1016\/j.cej.2025.164599","volume":"518","author":"Wang","year":"2025","journal-title":"Chem. Eng. J."},{"issue":"41","key":"D5BM01811K\/cit19\/1","doi-asserted-by":"crossref","first-page":"15040","DOI":"10.1021\/acs.nanolett.5c03911","volume":"25","author":"Yang","year":"2025","journal-title":"Nano Lett."},{"issue":"25","key":"D5BM01811K\/cit20\/1","doi-asserted-by":"crossref","first-page":"23276","DOI":"10.1021\/acsnano.5c06202","volume":"19","author":"Zhao","year":"2025","journal-title":"ACS Nano"}],"container-title":["Biomaterials Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2026\/BM\/D5BM01811K","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:51:38Z","timestamp":1782942698000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/bm\/article\/14\/9\/2463-2471\/1228943"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,5,5]]}},"URL":"https:\/\/doi.org\/10.1039\/d5bm01811k","relation":{},"ISSN":["2047-4830","2047-4849"],"issn-type":[{"value":"2047-4830","type":"print"},{"value":"2047-4849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}