{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:48:24Z","timestamp":1791409704081,"version":"4.3.3"},"reference-count":50,"publisher":"Royal Society of Chemistry (RSC)","issue":"10","license":[{"start":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:00:00Z","timestamp":1772496000000},"content-version":"vor","delay-in-days":61,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["16812307"],"award-info":[{"award-number":["16812307"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["24KK0103"],"award-info":[{"award-number":["24KK0103"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["22K04898"],"award-info":[{"award-number":["22K04898"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["24K01261"],"award-info":[{"award-number":["24K01261"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008732","name":"Uehara Memorial Foundation","doi-asserted-by":"publisher","award":["202380032"],"award-info":[{"award-number":["202380032"]}],"id":[{"id":"10.13039\/100008732","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","award":["JPMJPR16FA"],"award-info":[{"award-number":["JPMJPR16FA"]}],"id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","award":["JPMJMI19G6"],"award-info":[{"award-number":["JPMJMI19G6"]}],"id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","award":["JPMJFR244Y"],"award-info":[{"award-number":["JPMJFR244Y"]}],"id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003382","name":"Core Research for Evolutional Science and Technology","doi-asserted-by":"publisher","award":["JPMJCR2434"],"award-info":[{"award-number":["JPMJCR2434"]}],"id":[{"id":"10.13039\/501100003382","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Biomater. Sci."],"abstract":"<jats:p>A photoactivatable cell-anchoring surface enables image-guided single-cell isolation through localized light irradiation, allowing rapid and precise isolation of rare cells such as circulating tumor cells (CTCs) from densely populated samples.<\/jats:p>","DOI":"10.1039\/d5bm01883h","type":"journal-article","created":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T11:00:47Z","timestamp":1772535647000},"page":"2567-2574","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Image-based single-cell isolation in high-density seeded cells using photoactivatable surfaces"],"prefix":"10.1039","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8402-4514","authenticated-orcid":false,"given":"Shinya","family":"Yamahira","sequence":"first","affiliation":[{"name":"SANKEN, The University of Osaka, 8-1 Mihogaoka, Ibaraki-shi, Osaka 567-0047, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Umeda","sequence":"additional","affiliation":[{"name":"SANKEN, The University of Osaka, 8-1 Mihogaoka, Ibaraki-shi, Osaka 567-0047, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2435-0270","authenticated-orcid":false,"given":"Teruyuki","family":"Nagamune","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4822-7469","authenticated-orcid":false,"given":"Satoshi","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"SANKEN, The University of Osaka, 8-1 Mihogaoka, Ibaraki-shi, Osaka 567-0047, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D5BM01883H\/cit1\/1","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1039\/C8AN01186A","volume":"144","author":"Gao","year":"2019","journal-title":"Analyst"},{"key":"D5BM01883H\/cit2\/1","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1073\/pnas.1524813113","volume":"113","author":"Guo","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D5BM01883H\/cit3\/1","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s12938-015-0109-2","volume":"14","author":"Gou","year":"2015","journal-title":"Biomed. Eng. Online"},{"key":"D5BM01883H\/cit4\/1","doi-asserted-by":"crossref","first-page":"132173","DOI":"10.1016\/j.snb.2022.132173","volume":"368","author":"Zheng","year":"2022","journal-title":"Sens. Actuators, B"},{"key":"D5BM01883H\/cit5\/1","doi-asserted-by":"crossref","first-page":"2586","DOI":"10.1039\/D2LC01113A","volume":"23","author":"Chen","year":"2023","journal-title":"Lab Chip"},{"key":"D5BM01883H\/cit6\/1","doi-asserted-by":"crossref","first-page":"E3599","DOI":"10.1073\/pnas.1515364113","volume":"113","author":"Dura","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D5BM01883H\/cit7\/1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/s42003-021-02937-x","volume":"5","author":"Negishi","year":"2022","journal-title":"Commun. Biol."},{"key":"D5BM01883H\/cit8\/1","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.jid.2023.10.017","volume":"144","author":"Harris","year":"2024","journal-title":"J. Invest. Dermatol."},{"key":"D5BM01883H\/cit9\/1","doi-asserted-by":"crossref","first-page":"8050","DOI":"10.1021\/ac0515632","volume":"77","author":"Yamamura","year":"2005","journal-title":"Anal. Chem."},{"key":"D5BM01883H\/cit10\/1","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/j.molonc.2014.12.001","volume":"9","author":"Pestrin","year":"2015","journal-title":"Mol. Oncol."},{"key":"D5BM01883H\/cit11\/1","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1038\/bjc.2013.92","volume":"108","author":"Peeters","year":"2013","journal-title":"Br. J. Cancer"},{"key":"D5BM01883H\/cit12\/1","doi-asserted-by":"crossref","first-page":"3213","DOI":"10.1200\/JCO.2007.15.8923","volume":"26","author":"Cohen","year":"2008","journal-title":"J. Clin. Oncol."},{"key":"D5BM01883H\/cit13\/1","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1021\/acs.analchem.5b04077","volume":"88","author":"Hosic","year":"2016","journal-title":"Anal. Chem."},{"key":"D5BM01883H\/cit14\/1","doi-asserted-by":"crossref","first-page":"016601","DOI":"10.1088\/0034-4885\/78\/1\/016601","volume":"78","author":"Plouffe","year":"2015","journal-title":"Rep. Prog. Phys."},{"key":"D5BM01883H\/cit15\/1","doi-asserted-by":"crossref","first-page":"8439","DOI":"10.1038\/s41467-024-52388-1","volume":"15","author":"Bexte","year":"2024","journal-title":"Nat. Commun."},{"key":"D5BM01883H\/cit16\/1","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1063\/1.1685647","volume":"43","author":"Bonner","year":"1972","journal-title":"Rev. Sci. Instrum."},{"key":"D5BM01883H\/cit17\/1","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/cyto.990110203","volume":"11","author":"Miltenyi","year":"1990","journal-title":"Cytometry"},{"key":"D5BM01883H\/cit18\/1","first-page":"1179","volume":"33","author":"Henning","year":"2025","journal-title":"Mol. Ther."},{"key":"D5BM01883H\/cit19\/1","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1002\/mabi.201400312","volume":"14","author":"Yamahira","year":"2014","journal-title":"Macromol. Biosci."},{"key":"D5BM01883H\/cit20\/1","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1039\/C7LC00198C","volume":"17","author":"Tan","year":"2017","journal-title":"Lab Chip"},{"key":"D5BM01883H\/cit21\/1","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1186\/s12859-021-04270-w","volume":"22","author":"Wu","year":"2021","journal-title":"BMC Bioinf."},{"key":"D5BM01883H\/cit22\/1","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1016\/j.cell.2024.03.035","volume":"187","author":"Song","year":"2024","journal-title":"Cell"},{"key":"D5BM01883H\/cit23\/1","first-page":"19","volume":"44","author":"Yang","year":"2014","journal-title":"Ann. Clin. Lab. Sci."},{"key":"D5BM01883H\/cit24\/1","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.jbiosc.2025.01.004","volume":"139","author":"Shiina","year":"2025","journal-title":"J. Biosci. Bioeng."},{"key":"D5BM01883H\/cit25\/1","first-page":"101536","volume":"2012","author":"Chen","year":"2012","journal-title":"Comput. Math. Methods Med."},{"key":"D5BM01883H\/cit26\/1","doi-asserted-by":"crossref","first-page":"34009","DOI":"10.1038\/srep34009","volume":"6","author":"Kato","year":"2016","journal-title":"Sci. Rep."},{"key":"D5BM01883H\/cit27\/1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.2144\/05383RV01","volume":"38","author":"Voss","year":"2005","journal-title":"BioTechniques"},{"key":"D5BM01883H\/cit28\/1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.jconrel.2023.11.023","volume":"365","author":"Sun","year":"2024","journal-title":"J. Controlled Release"},{"key":"D5BM01883H\/cit29\/1","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1186\/s13287-022-03223-1","volume":"13","author":"Sano","year":"2022","journal-title":"Stem Cell Res. Ther."},{"key":"D5BM01883H\/cit30\/1","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1038\/srep01191","volume":"3","author":"Yoshimoto","year":"2013","journal-title":"Sci. Rep."},{"key":"D5BM01883H\/cit31\/1","doi-asserted-by":"crossref","first-page":"e13179","DOI":"10.1371\/journal.pone.0013179","volume":"5","author":"Yatsushiro","year":"2010","journal-title":"PLoS One"},{"key":"D5BM01883H\/cit32\/1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/s41378-024-00750-0","volume":"10","author":"Tian","year":"2024","journal-title":"Microsyst. Nanoeng."},{"key":"D5BM01883H\/cit33\/1","doi-asserted-by":"crossref","first-page":"1900247","DOI":"10.1002\/biot.201900247","volume":"15","author":"Le","year":"2020","journal-title":"Biotechnol. J."},{"key":"D5BM01883H\/cit34\/1","doi-asserted-by":"crossref","first-page":"e3192","DOI":"10.1002\/btpr.3192","volume":"37","author":"Diep","year":"2021","journal-title":"Biotechnol. Prog."},{"key":"D5BM01883H\/cit35\/1","doi-asserted-by":"crossref","first-page":"13154","DOI":"10.1021\/jacs.2c02949","volume":"144","author":"Yamahira","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"D5BM01883H\/cit36\/1","first-page":"100473","volume":"18","author":"Yamahira","year":"2024","journal-title":"Biosens. Bioelectron.: X"},{"key":"D5BM01883H\/cit37\/1","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/j.bbrc.2013.11.014","volume":"441","author":"Lee","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"D5BM01883H\/cit38\/1","doi-asserted-by":"crossref","first-page":"44077","DOI":"10.1038\/srep44077","volume":"7","author":"Ishijima","year":"2017","journal-title":"Sci. Rep."},{"key":"D5BM01883H\/cit39\/1","doi-asserted-by":"crossref","first-page":"4514","DOI":"10.1039\/C9BM01200A","volume":"7","author":"Jarz\u0119bska","year":"2020","journal-title":"Biomater. Sci."},{"key":"D5BM01883H\/cit40\/1","doi-asserted-by":"crossref","first-page":"17980","DOI":"10.1021\/jacs.2c07321","volume":"144","author":"Kosaka","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"D5BM01883H\/cit41\/1","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1039\/D5LC00102A","volume":"25","author":"Umeda","year":"2025","journal-title":"Lab Chip"},{"key":"D5BM01883H\/cit42\/1","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.1039\/c2lc21099a","volume":"12","author":"Landenberger","year":"2012","journal-title":"Lab Chip"},{"key":"D5BM01883H\/cit43\/1","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1098\/rsif.2008.0052","volume":"5","author":"Zhang","year":"2008","journal-title":"J. R. Soc., Interface"},{"key":"D5BM01883H\/cit44\/1","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1038\/s41596-023-00844-5","volume":"18","author":"Yang","year":"2023","journal-title":"Nat. Protoc."},{"key":"D5BM01883H\/cit45\/1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1039\/B906593H","volume":"10","author":"Hsu","year":"2010","journal-title":"Lab Chip"},{"key":"D5BM01883H\/cit46\/1","doi-asserted-by":"crossref","first-page":"15757","DOI":"10.1073\/pnas.0507719102","volume":"102","author":"Hu","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D5BM01883H\/cit47\/1","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1038\/nature03831","volume":"436","author":"Chiou","year":"2005","journal-title":"Nature"},{"key":"D5BM01883H\/cit48\/1","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1083\/jcb.201010021","volume":"192","author":"Yu","year":"2011","journal-title":"J. Cell Biol."},{"key":"D5BM01883H\/cit49\/1","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nrc3820","volume":"14","author":"Alix-Panabi\u00e8res","year":"2014","journal-title":"Nat. Rev. Cancer"},{"key":"D5BM01883H\/cit50\/1","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/s41571-019-0187-3","volume":"16","author":"Pantel","year":"2019","journal-title":"Nat. Rev. Clin. Oncol."}],"container-title":["Biomaterials Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2026\/BM\/D5BM01883H","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2026\/BM\/D5BM01883H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:23:28Z","timestamp":1782941008000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/bm\/article\/14\/10\/2567-2574\/1242548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":50,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,5,19]]}},"URL":"https:\/\/doi.org\/10.1039\/d5bm01883h","relation":{},"ISSN":["2047-4830","2047-4849"],"issn-type":[{"value":"2047-4830","type":"print"},{"value":"2047-4849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}