{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T05:51:51Z","timestamp":1792648311087,"version":"4.5.0"},"reference-count":58,"publisher":"Royal Society of Chemistry (RSC)","issue":"14","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"am","delay-in-days":429,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22107074"],"award-info":[{"award-number":["22107074"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"publisher","award":["202102021223"],"award-info":[{"award-number":["202102021223"]}],"id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515011356"],"award-info":[{"award-number":["2022A1515011356"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515030157"],"award-info":[{"award-number":["2024A1515030157"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Dalton Trans."],"abstract":"<jats:p>\n                    This paper describes the design of Ru(\n                    <jats:sc>ii<\/jats:sc>\n                    )-based phototherapeutic agents capable of generating\n                    <jats:sup>1<\/jats:sup>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    and releasing NO effectively upon light irradiation.\n                  <\/jats:p>","DOI":"10.1039\/d5dt00038f","type":"journal-article","created":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T03:41:17Z","timestamp":1741232477000},"page":"5753-5763","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Phototherapeutic activity of polypyridyl ruthenium(\n                    <scp>ii<\/scp>\n                    ) complexes through synergistic action of nitric oxide and singlet oxygen"],"prefix":"10.1039","volume":"54","author":[{"given":"Jia-Hao","family":"Dong","sequence":"first","affiliation":[{"name":"Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bai-Hua","family":"Chen","sequence":"additional","affiliation":[{"name":"Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Jiang","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Shenzhen Technology University, Shenzhen 518118, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Yin","family":"Wu","sequence":"additional","affiliation":[{"name":"Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Wen","family":"Feng","sequence":"additional","affiliation":[{"name":"Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Hao","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1385-4035","authenticated-orcid":false,"given":"Zheng-Yin","family":"Pan","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Shenzhen Technology University, Shenzhen 518118, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1130-4945","authenticated-orcid":false,"given":"Yingju","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9090-3806","authenticated-orcid":false,"given":"Liang","family":"He","sequence":"additional","affiliation":[{"name":"Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D5DT00038F\/cit1\/1","doi-asserted-by":"crossref","first-page":"2006742","DOI":"10.1002\/smll.202006742","volume":"17","author":"Chen","year":"2021","journal-title":"Small"},{"key":"D5DT00038F\/cit2\/1","doi-asserted-by":"crossref","first-page":"7987","DOI":"10.1021\/acsami.0c21309","volume":"13","author":"Ma","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D5DT00038F\/cit3\/1","doi-asserted-by":"crossref","first-page":"10887","DOI":"10.1021\/acsnano.9b04954","volume":"13","author":"Chen","year":"2019","journal-title":"ACS Nano"},{"key":"D5DT00038F\/cit4\/1","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1186\/s12951-021-01078-x","volume":"19","author":"Liu","year":"2021","journal-title":"J. Nanobiotechnol."},{"key":"D5DT00038F\/cit5\/1","doi-asserted-by":"crossref","first-page":"108502","DOI":"10.1016\/j.pharmthera.2023.108502","volume":"249","author":"Oza","year":"2023","journal-title":"Pharmacol. Ther."},{"key":"D5DT00038F\/cit6\/1","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1038\/nrc1910","volume":"6","author":"Fukumura","year":"2006","journal-title":"Nat. Rev. Cancer"},{"key":"D5DT00038F\/cit7\/1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1089\/152308603322110887","volume":"5","author":"Thomas","year":"2003","journal-title":"Antioxid. Redox Signaling"},{"key":"D5DT00038F\/cit8\/1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1039\/C5TB02215K","volume":"4","author":"Wang","year":"2016","journal-title":"J. Mater. Chem. B"},{"key":"D5DT00038F\/cit9\/1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1039\/C4CC07827F","volume":"51","author":"Fowley","year":"2015","journal-title":"Chem. Commun."},{"key":"D5DT00038F\/cit10\/1","doi-asserted-by":"crossref","first-page":"7046","DOI":"10.1002\/anie.202015082","volume":"60","author":"Fang","year":"2021","journal-title":"Angew. Chem., Int. Ed."},{"key":"D5DT00038F\/cit11\/1","doi-asserted-by":"crossref","first-page":"8935","DOI":"10.1021\/acsnano.3c02303","volume":"17","author":"Wang","year":"2023","journal-title":"ACS Nano"},{"key":"D5DT00038F\/cit12\/1","first-page":"E10127","volume":"115","author":"Wang","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D5DT00038F\/cit13\/1","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1158\/1078-0432.CCR-22-2791","volume":"29","author":"Reddy","year":"2023","journal-title":"Clin. Cancer Res."},{"key":"D5DT00038F\/cit14\/1","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/s41523-020-00204-6","volume":"6","author":"Jindal","year":"2020","journal-title":"npj Breast Cancer"},{"key":"D5DT00038F\/cit15\/1","doi-asserted-by":"crossref","first-page":"13534","DOI":"10.1074\/jbc.RA117.000287","volume":"293","author":"Maiuthed","year":"2018","journal-title":"J. Biol. Chem."},{"key":"D5DT00038F\/cit16\/1","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/nrc1894","volume":"6","author":"Castano","year":"2006","journal-title":"Nat. Rev. Cancer"},{"key":"D5DT00038F\/cit17\/1","doi-asserted-by":"crossref","first-page":"17760","DOI":"10.1039\/D4SC04608K","volume":"15","author":"Kuznetsov","year":"2024","journal-title":"Chem. Sci."},{"key":"D5DT00038F\/cit18\/1","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1039\/D2SC05672K","volume":"14","author":"Madec","year":"2023","journal-title":"Chem. Sci."},{"key":"D5DT00038F\/cit19\/1","doi-asserted-by":"crossref","first-page":"23397","DOI":"10.1021\/jacs.3c01135","volume":"145","author":"Bonnet","year":"2023","journal-title":"J. Am. Chem. Soc."},{"key":"D5DT00038F\/cit20\/1","doi-asserted-by":"crossref","first-page":"214656","DOI":"10.1016\/j.ccr.2022.214656","volume":"469","author":"Conti","year":"2022","journal-title":"Coord. Chem. Rev."},{"key":"D5DT00038F\/cit21\/1","doi-asserted-by":"crossref","first-page":"9694","DOI":"10.1039\/D2CS00379A","volume":"51","author":"Martin","year":"2022","journal-title":"Chem. Soc. Rev."},{"key":"D5DT00038F\/cit22\/1","doi-asserted-by":"crossref","first-page":"8825","DOI":"10.1021\/acs.chemrev.3c00629","volume":"124","author":"Lee","year":"2024","journal-title":"Chem. Rev."},{"key":"D5DT00038F\/cit23\/1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/anie.201905171","volume":"59","author":"Imberti","year":"2020","journal-title":"Angew. Chem., Int. Ed."},{"key":"D5DT00038F\/cit24\/1","doi-asserted-by":"crossref","first-page":"213736","DOI":"10.1016\/j.ccr.2020.213736","volume":"434","author":"Mart\u00ednez Alonso","year":"2021","journal-title":"Coord. Chem. Rev."},{"key":"D5DT00038F\/cit25\/1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0010-8545(88)80032-8","volume":"84","author":"Juris","year":"1988","journal-title":"Coord. Chem. Rev."},{"key":"D5DT00038F\/cit26\/1","doi-asserted-by":"crossref","first-page":"7317","DOI":"10.1039\/C7CS00356K","volume":"46","author":"Notaro","year":"2017","journal-title":"Chem. Soc. Rev."},{"key":"D5DT00038F\/cit27\/1","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1021\/acs.chemrev.8b00211","volume":"119","author":"Monro","year":"2019","journal-title":"Chem. Rev."},{"key":"D5DT00038F\/cit28\/1","first-page":"105","volume":"41","author":"Kulkarni","year":"2022","journal-title":"Eur. Urol., Suppl."},{"key":"D5DT00038F\/cit29\/1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ccr.2014.04.012","volume":"282\u2013283","author":"Shi","year":"2015","journal-title":"Coord. Chem. Rev."},{"key":"D5DT00038F\/cit30\/1","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1080\/00958972.2018.1469129","volume":"71","author":"Crisalli","year":"2018","journal-title":"J. Coord. Chem."},{"key":"D5DT00038F\/cit31\/1","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1002\/ejic.201601233","volume":"2017","author":"Vorobyev","year":"2017","journal-title":"Eur. J. Inorg. Chem."},{"key":"D5DT00038F\/cit32\/1","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1039\/C9DT04219A","volume":"49","author":"Fung","year":"2020","journal-title":"Dalton Trans."},{"key":"D5DT00038F\/cit33\/1","doi-asserted-by":"crossref","first-page":"5367","DOI":"10.1039\/D2DT00290F","volume":"51","author":"Stepanenko","year":"2022","journal-title":"Dalton Trans."},{"key":"D5DT00038F\/cit34\/1","doi-asserted-by":"crossref","first-page":"8103","DOI":"10.1039\/C8SC03386B","volume":"9","author":"Wang","year":"2018","journal-title":"Chem. Sci."},{"key":"D5DT00038F\/cit35\/1","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1039\/b800132d","volume":"17","author":"Callari","year":"2008","journal-title":"Chem. Commun."},{"key":"D5DT00038F\/cit36\/1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1039\/C1JM13288A","volume":"22","author":"Sortino","year":"2012","journal-title":"J. Mater. Chem."},{"key":"D5DT00038F\/cit37\/1","doi-asserted-by":"crossref","first-page":"12714","DOI":"10.1002\/chem.202101662","volume":"27","author":"Fraix","year":"2021","journal-title":"Chem. \u2013 Eur. J."},{"key":"D5DT00038F\/cit38\/1","doi-asserted-by":"crossref","first-page":"16932","DOI":"10.1021\/acs.jmedchem.4c01038","volume":"67","author":"Parisi","year":"2024","journal-title":"J. Med. Chem."},{"key":"D5DT00038F\/cit39\/1","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1039\/b102359b","volume":"13","author":"Sortino","year":"2001","journal-title":"Chem. Commun."},{"key":"D5DT00038F\/cit40\/1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1562\/0031-8655(2001)0730006TPOFAI2.0.CO2","volume":"73","author":"Sortino","year":"2007","journal-title":"Photochem. Photobiol."},{"key":"D5DT00038F\/cit41\/1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/zaac.201900286","volume":"646","author":"Zhang","year":"2020","journal-title":"Z. Anorg. Allg. Chem."},{"key":"D5DT00038F\/cit42\/1","doi-asserted-by":"crossref","first-page":"3528","DOI":"10.1002\/chem.200501240","volume":"12","author":"Li","year":"2006","journal-title":"Chem. \u2013 Eur. J."},{"key":"D5DT00038F\/cit43\/1","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/ejic.201301150","volume":"2014","author":"Mori","year":"2014","journal-title":"Eur. J. Inorg. Chem."},{"key":"D5DT00038F\/cit44\/1","doi-asserted-by":"crossref","first-page":"115482","DOI":"10.1016\/j.molliq.2021.115482","volume":"328","author":"Warad","year":"2021","journal-title":"J. Mol. Liq."},{"key":"D5DT00038F\/cit45\/1","doi-asserted-by":"crossref","first-page":"4167","DOI":"10.1021\/ic902533x","volume":"49","author":"Kar","year":"2010","journal-title":"Inorg. Chem."},{"key":"D5DT00038F\/cit46\/1","doi-asserted-by":"crossref","first-page":"4360","DOI":"10.1039\/C9SC06272F","volume":"11","author":"Kunnus","year":"2020","journal-title":"Chem. Sci."},{"key":"D5DT00038F\/cit47\/1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.poly.2019.03.015","volume":"165","author":"He","year":"2019","journal-title":"Polyhedron"},{"key":"D5DT00038F\/cit48\/1","doi-asserted-by":"crossref","first-page":"5002","DOI":"10.1039\/C5NJ03329B","volume":"40","author":"Shee","year":"2016","journal-title":"New J. Chem."},{"key":"D5DT00038F\/cit49\/1","doi-asserted-by":"crossref","first-page":"117132","DOI":"10.1016\/j.saa.2019.05.037","volume":"220","author":"Jiang","year":"2019","journal-title":"Spectrochim. Acta, Part A"},{"key":"D5DT00038F\/cit50\/1","doi-asserted-by":"crossref","first-page":"11822","DOI":"10.1039\/C9DT01650C","volume":"48","author":"Srivastava","year":"2019","journal-title":"Dalton Trans."},{"key":"D5DT00038F\/cit51\/1","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.jinorgbio.2018.01.003","volume":"180","author":"Florence Tikum","year":"2018","journal-title":"J. Inorg. Biochem."},{"key":"D5DT00038F\/cit52\/1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jphotobiol.2014.09.003","volume":"141","author":"Srishailam","year":"2014","journal-title":"J. Photochem. Photobiol., B"},{"key":"D5DT00038F\/cit53\/1","doi-asserted-by":"crossref","first-page":"10472","DOI":"10.1039\/C9CC04871E","volume":"55","author":"He","year":"2019","journal-title":"Chem. Commun."},{"key":"D5DT00038F\/cit54\/1","doi-asserted-by":"crossref","first-page":"eadq0839","DOI":"10.1126\/sciadv.adq0839","volume":"10","author":"Zhang","year":"2024","journal-title":"Sci. Adv."},{"key":"D5DT00038F\/cit55\/1","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s11060-019-03103-4","volume":"141","author":"Mahmoudi","year":"2019","journal-title":"J. Neuro-Oncol."},{"key":"D5DT00038F\/cit56\/1","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1562\/0031-8655(2001)0740760QOSMOO2.0.CO2","volume":"74","author":"Li","year":"2007","journal-title":"Photochem. Photobiol."},{"key":"D5DT00038F\/cit57\/1","doi-asserted-by":"crossref","first-page":"5453","DOI":"10.1002\/chem.202004698","volume":"27","author":"Zhao","year":"2021","journal-title":"Chem. \u2013 Eur. J."},{"key":"D5DT00038F\/cit58\/1","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1021\/acsnano.1c09048","volume":"16","author":"Jiang","year":"2022","journal-title":"ACS Nano"}],"container-title":["Dalton Transactions"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/DT\/D5DT00038F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T18:45:06Z","timestamp":1783449906000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/dt\/article\/54\/14\/5753-5763\/889288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":58,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2025,4,1]]}},"URL":"https:\/\/doi.org\/10.1039\/d5dt00038f","relation":{},"ISSN":["1477-9226","1477-9234"],"issn-type":[{"value":"1477-9226","type":"print"},{"value":"1477-9234","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}