{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:10:36Z","timestamp":1787508636186,"version":"build-2736575974"},"reference-count":59,"publisher":"Royal Society of Chemistry (RSC)","issue":"7","license":[{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"vor","delay-in-days":154,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Environ. Sci.: Processes Impacts"],"abstract":"<jats:p>Secondary cyanometabolite mixtures vary spatiotemporally in ways not fully captured by the same-scale ELISA measurements or by beach-averaged weekly microcystin monitoring.<\/jats:p>","DOI":"10.1039\/d5em01071c","type":"journal-article","created":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T13:23:04Z","timestamp":1780579384000},"page":"1998-2008","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Spatial and temporal variation of suspect screening derived cyanobacterial secondary metabolite mixtures during harmful algal bloom events in shallow agroecosystem lakes"],"prefix":"10.1039","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2046-2179","authenticated-orcid":false,"given":"Stanley W.","family":"Kohls","sequence":"first","affiliation":[{"name":"Department of Civil and Environmental Engineering, University of Iowa, 4105 Seamans Center, Iowa, 52242, USA"},{"name":"IIHR\u2014Hydroscience and Engineering, University of Iowa, 100 C. Maxwell Stanley Hydraulics Laboratory, Iowa, 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyndy","family":"Holdt","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa 52242, USA"},{"name":"Friends of Lakeside Lab, 1838 Highway 86, Milford, IA 51351, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nervana","family":"Metwali","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corey D.","family":"Markfort","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering, University of Iowa, 4105 Seamans Center, Iowa, 52242, USA"},{"name":"IIHR\u2014Hydroscience and Engineering, University of Iowa, 100 C. Maxwell Stanley Hydraulics Laboratory, Iowa, 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter S.","family":"Thorne","sequence":"additional","affiliation":[{"name":"Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7746-0297","authenticated-orcid":false,"given":"Gregory H.","family":"LeFevre","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering, University of Iowa, 4105 Seamans Center, Iowa, 52242, USA"},{"name":"IIHR\u2014Hydroscience and Engineering, University of Iowa, 100 C. Maxwell Stanley Hydraulics Laboratory, Iowa, 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"issue":"9","key":"D5EM01071C\/cit1\/1","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1038\/s43017-024-00578-2","volume":"5","author":"Feng","year":"2024","journal-title":"Nat. Rev. Earth Environ."},{"issue":"7","key":"D5EM01071C\/cit2\/1","doi-asserted-by":"publisher","first-page":"2327","DOI":"10.1111\/gcb.16077","volume":"28","author":"Fang","year":"2022","journal-title":"Glob. Change Biol."},{"issue":"12","key":"D5EM01071C\/cit3\/1","doi-asserted-by":"publisher","first-page":"551","DOI":"10.3390\/toxins16120551","volume":"16","author":"Al Haffar","year":"2024","journal-title":"Toxins"},{"key":"D5EM01071C\/cit4\/1","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.envint.2013.06.013","volume":"59","author":"Merel","year":"2013","journal-title":"Environ. Int."},{"issue":"32","key":"D5EM01071C\/cit5\/1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1021\/cen-09232-notw8","volume":"92","author":"Wilson","year":"2014","journal-title":"Chem. Eng. News"},{"issue":"7","key":"D5EM01071C\/cit6\/1","doi-asserted-by":"publisher","first-page":"4443","DOI":"10.1007\/s10661-014-3710-0","volume":"186","author":"Koreivien\u0117","year":"2014","journal-title":"Environ. Monit. Assess."},{"issue":"5917","key":"D5EM01071C\/cit7\/1","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.1126\/science.1167755","volume":"323","author":"Conley","year":"2009","journal-title":"Science"},{"issue":"1","key":"D5EM01071C\/cit8\/1","doi-asserted-by":"publisher","first-page":"113","DOI":"10.2134\/jeq2017.08.0338","volume":"47","author":"Jacquemin","year":"2018","journal-title":"J. Environ. Qual."},{"key":"D5EM01071C\/cit9\/1","doi-asserted-by":"publisher","first-page":"117141","DOI":"10.1016\/j.jenvman.2022.117141","volume":"330","author":"Summers","year":"2023","journal-title":"J. Environ. Manage."},{"issue":"4","key":"D5EM01071C\/cit10\/1","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1086\/678465","volume":"33","author":"Yuan","year":"2014","journal-title":"Freshw. Sci."},{"issue":"10","key":"D5EM01071C\/cit11\/1","doi-asserted-by":"publisher","first-page":"e2020WR028946","DOI":"10.1029\/2020WR028946","volume":"57","author":"Iiames","year":"2021","journal-title":"Water Resour. Res."},{"issue":"4","key":"D5EM01071C\/cit12\/1","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1007\/s42452-021-04521-8","volume":"3","author":"Singh","year":"2021","journal-title":"SN Appl. Sci."},{"key":"D5EM01071C\/cit13\/1","volume-title":"Voluntary Measures May Not Be Enough: Bacteria and Algae Plague Iowa Beaches","author":"Miller","year":"2024","unstructured":"J. B.Miller ,  M.Cordero  and  E.Jordan ,  Voluntary Measures May Not Be Enough: Bacteria and Algae Plague Iowa Beaches ,  TheGazette ,  CedarRapid , August  2024 .  https:\/\/www.thegazette.com\/environment-nature\/iowa-beaches-have-been-plagued-for-two-decades-by-algae-bacteria-why-experts-say-we-need-to-be-doi\/ , accessed 2025-01-14"},{"key":"D5EM01071C\/cit14\/1","author":"Iowa","unstructured":"D. N. R.Iowa ,  AQuIA, Beach Monitoring ,  https:\/\/programs.iowadnr.gov\/aquia\/beaches , accessed 2025-04-09"},{"issue":"8","key":"D5EM01071C\/cit15\/1","doi-asserted-by":"publisher","first-page":"3423","DOI":"10.1021\/acsestwater.4c00266","volume":"4","author":"Maurer","year":"2024","journal-title":"ACS ES&T Water"},{"key":"D5EM01071C\/cit16\/1","doi-asserted-by":"publisher","first-page":"117017","DOI":"10.1016\/j.watres.2021.117017","volume":"196","author":"Jones","year":"2021","journal-title":"Water Res."},{"key":"D5EM01071C\/cit17\/1","doi-asserted-by":"publisher","first-page":"164725","DOI":"10.1016\/j.scitotenv.2023.164725","volume":"892","author":"Zervou","year":"2023","journal-title":"Sci. Total Environ."},{"key":"D5EM01071C\/cit18\/1","doi-asserted-by":"publisher","first-page":"233","DOI":"10.3390\/toxins15030233","author":"Nugumanova","year":"2023","journal-title":"Toxins"},{"issue":"10","key":"D5EM01071C\/cit19\/1","doi-asserted-by":"publisher","first-page":"641","DOI":"10.3390\/toxins12100641","volume":"12","author":"Massey","year":"2020","journal-title":"Toxins"},{"key":"D5EM01071C\/cit20\/1","doi-asserted-by":"publisher","first-page":"143327","DOI":"10.1016\/j.scitotenv.2020.143327","volume":"760","author":"Douglas Greene","year":"2021","journal-title":"Sci. Total Environ."},{"key":"D5EM01071C\/cit21\/1","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1016\/j.watres.2018.12.048","volume":"151","author":"Janssen","year":"2019","journal-title":"Water Res."},{"issue":"1","key":"D5EM01071C\/cit22\/1","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3390\/toxins13010023","volume":"13","author":"Savadova-Ratkus","year":"2021","journal-title":"Toxins"},{"issue":"5","key":"D5EM01071C\/cit23\/1","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1093\/plankt\/11.5.925","volume":"11","author":"Galat","year":"1989","journal-title":"J. Plankton Res."},{"key":"D5EM01071C\/cit24\/1","doi-asserted-by":"publisher","first-page":"3354","DOI":"10.3390\/toxins6123354","author":"Schmidt","year":"2014","journal-title":"Toxins"},{"issue":"1","key":"D5EM01071C\/cit25\/1","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1086\/303220","volume":"154","author":"Huisman","year":"1999","journal-title":"Am. Nat."},{"issue":"4","key":"D5EM01071C\/cit26\/1","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1093\/plankt\/6.4.699","volume":"6","author":"Trimbee","year":"1984","journal-title":"J. Plankton Res."},{"issue":"11","key":"D5EM01071C\/cit27\/1","doi-asserted-by":"publisher","first-page":"2064","DOI":"10.1111\/fwb.13814","volume":"66","author":"Ortiz","year":"2021","journal-title":"Freshw. Biol."},{"key":"D5EM01071C\/cit28\/1","doi-asserted-by":"publisher","first-page":"125560","DOI":"10.1016\/j.jhazmat.2021.125560","volume":"415","author":"Christensen","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"D5EM01071C\/cit29\/1","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.watres.2017.04.025","volume":"118","author":"Gaget","year":"2017","journal-title":"Water Res."},{"key":"D5EM01071C\/cit30\/1","doi-asserted-by":"publisher","first-page":"119367","DOI":"10.1016\/j.watres.2022.119367","volume":"228","author":"Wang","year":"2023","journal-title":"Water Res."},{"issue":"1","key":"D5EM01071C\/cit31\/1","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s00216-022-04434-4","volume":"415","author":"Black","year":"2023","journal-title":"Anal. Bioanal. Chem."},{"issue":"38","key":"D5EM01071C\/cit32\/1","doi-asserted-by":"publisher","first-page":"20726","DOI":"10.1021\/acs.est.5c09247","volume":"59","author":"Wang","year":"2025","journal-title":"Environ. Sci. Technol."},{"issue":"21","key":"D5EM01071C\/cit33\/1","doi-asserted-by":"publisher","first-page":"4829","DOI":"10.1007\/s00216-025-05999-6","volume":"417","author":"Roy-Lachapelle","year":"2025","journal-title":"Anal. Bioanal. Chem."},{"key":"D5EM01071C\/cit34\/1","doi-asserted-by":"publisher","first-page":"173023","DOI":"10.1016\/j.scitotenv.2024.173023","volume":"932","author":"Shang","year":"2024","journal-title":"Sci. Total Environ."},{"key":"D5EM01071C\/cit35\/1","doi-asserted-by":"publisher","first-page":"102429","DOI":"10.1016\/j.hal.2023.102429","volume":"125","author":"Aguilera","year":"2023","journal-title":"Harmful Algae"},{"issue":"17","key":"D5EM01071C\/cit36\/1","doi-asserted-by":"publisher","first-page":"11991","DOI":"10.1021\/acs.est.2c02763","volume":"56","author":"Agathokleous","year":"2022","journal-title":"Environ. Sci. Technol."},{"issue":"3","key":"D5EM01071C\/cit37\/1","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1080\/10402381.2020.1863530","volume":"37","author":"Hardy","year":"2021","journal-title":"Lake Reserv. Manag."},{"issue":"12","key":"D5EM01071C\/cit38\/1","doi-asserted-by":"publisher","first-page":"684","DOI":"10.3390\/toxins15120684","volume":"15","author":"Pierce","year":"2023","journal-title":"Toxins"},{"key":"D5EM01071C\/cit39\/1","first-page":"1","volume-title":"Method 546: Determination of Total Microcystins and Nodularins in Drinking Water and Ambient Water by Adda Enzyme-Linked Immunosorbent Assay","author":"Zaffiro","year":"2016","unstructured":"A.Zaffiro ,  L.Rosenblum  and  S. C.Wendelken ,  Method 546: Determination of Total Microcystins and Nodularins in Drinking Water and Ambient Water by Adda Enzyme-Linked Immunosorbent Assay ,  United States Environ. Prot. Agency ,  2016 ,  pp. 1\u201321 , No. 815-B-16\u2013011"},{"key":"D5EM01071C\/cit40\/1","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.chemosphere.2017.05.106","volume":"183","author":"Haque","year":"2017","journal-title":"Chemosphere"},{"issue":"41","key":"D5EM01071C\/cit41\/1","doi-asserted-by":"publisher","first-page":"13870","DOI":"10.1021\/acs.analchem.1c02621","volume":"93","author":"Peter","year":"2021","journal-title":"Anal. Chem."},{"issue":"1","key":"D5EM01071C\/cit42\/1","doi-asserted-by":"publisher","first-page":"1752","DOI":"10.1038\/s41467-023-37446-4","volume":"14","author":"de Jonge","year":"2023","journal-title":"Nat. Commun."},{"issue":"8","key":"D5EM01071C\/cit43\/1","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1038\/nbt.3597","volume":"34","author":"Wang","year":"2016","journal-title":"Nat. Biotechnol."},{"issue":"4","key":"D5EM01071C\/cit44\/1","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.1021\/es5002105","volume":"48","author":"Schymanski","year":"2014","journal-title":"Environ. Sci. Technol."},{"issue":"6","key":"D5EM01071C\/cit45\/1","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1002\/nt.2620010606","volume":"1","author":"Park","year":"1993","journal-title":"Nat. Toxins"},{"key":"D5EM01071C\/cit46\/1","doi-asserted-by":"publisher","first-page":"530","DOI":"10.3390\/toxins11090530","author":"Du","year":"2019","journal-title":"Toxins"},{"key":"D5EM01071C\/cit47\/1","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3390\/md14010008","author":"Spoof","year":"2016","journal-title":"Mar. Drugs"},{"key":"D5EM01071C\/cit48\/1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3354\/meps301303","volume":"301","author":"Ramos","year":"2005","journal-title":"Mar. Ecol. Prog. Ser."},{"issue":"4","key":"D5EM01071C\/cit49\/1","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1007\/s00248-009-9540-x","volume":"58","author":"Gantar","year":"2009","journal-title":"Microb. Ecol."},{"issue":"4","key":"D5EM01071C\/cit50\/1","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1111\/j.1462-2920.2010.02388.x","volume":"13","author":"Stani\u0107","year":"2011","journal-title":"Environ. Microbiol."},{"key":"D5EM01071C\/cit51\/1","doi-asserted-by":"publisher","first-page":"137012","DOI":"10.1016\/j.chemosphere.2022.137012","volume":"311","author":"Varriale","year":"2023","journal-title":"Chemosphere"},{"issue":"11","key":"D5EM01071C\/cit52\/1","doi-asserted-by":"publisher","first-page":"2064","DOI":"10.1111\/fwb.13814","volume":"66","author":"Ortiz","year":"2021","journal-title":"Freshw. Biol."},{"key":"D5EM01071C\/cit53\/1","doi-asserted-by":"publisher","first-page":"178230","DOI":"10.1016\/j.scitotenv.2024.178230","volume":"959","author":"Mart\u00ednez-Piernas","year":"2025","journal-title":"Sci. Total Environ."},{"issue":"2","key":"D5EM01071C\/cit54\/1","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1021\/envhealth.4c00149","volume":"3","author":"Feng","year":"2025","journal-title":"Environ. Health"},{"issue":"22","key":"D5EM01071C\/cit55\/1","doi-asserted-by":"publisher","first-page":"15196","DOI":"10.1021\/acs.est.1c04194","volume":"55","author":"Natumi","year":"2021","journal-title":"Environ. Sci. Technol."},{"issue":"5","key":"D5EM01071C\/cit56\/1","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1021\/np200106b","volume":"74","author":"Pereira","year":"2011","journal-title":"J. Nat. Prod."},{"issue":"399","key":"D5EM01071C\/cit57\/1","doi-asserted-by":"publisher","DOI":"10.3389\/fmars.2019.00399","volume":"6","author":"Stauffer","year":"2019","journal-title":"Front. Mar. Sci."},{"issue":"37","key":"D5EM01071C\/cit58\/1","doi-asserted-by":"publisher","first-page":"16560","DOI":"10.1021\/acs.est.4c04813","volume":"58","author":"Wang","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"D5EM01071C\/cit59\/1","doi-asserted-by":"publisher","first-page":"108585","DOI":"10.1016\/j.envint.2024.108585","volume":"186","author":"Tkalec","year":"2024","journal-title":"Environ. Int."}],"container-title":["Environmental Science: Processes &amp; Impacts"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/EM\/article-pdf\/doi\/10.1039\/D5EM01071C\/0\/D5EM01071C.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T14:30:50Z","timestamp":1784730650000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/EM\/article-lookup\/doi\/10.1039\/D5EM01071C"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":59,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7,22]]}},"URL":"https:\/\/doi.org\/10.1039\/d5em01071c","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D5EM01071C\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5EM01071C\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5EM01071C\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5EM01071C\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5EM01071C\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5EM01071C\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5EM01071C\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5EM01071C\/v1\/review1","asserted-by":"object"}]},"ISSN":["2050-7887","2050-7895"],"issn-type":[{"value":"2050-7887","type":"print"},{"value":"2050-7895","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}