{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:29:23Z","timestamp":1790713763793,"version":"4.1.0"},"reference-count":56,"publisher":"Royal Society of Chemistry (RSC)","issue":"12","license":[{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"am","delay-in-days":508,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    <jats:italic>L. rhamnosus<\/jats:italic>\n                    FSJ13 enhanced FGF21 expression, thereby inhibiting the TGF-\u03b2\/Smad2\/3 signaling pathway and subsequently attenuating pancreatic fibrosis.\n                  <\/jats:p>","DOI":"10.1039\/d5fo00832h","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T19:02:14Z","timestamp":1748026934000},"page":"5076-5087","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["<i>Lactobacillus rhamnosus<\/i>\n                    FSJ13 alleviates pancreatic fibrosis in mice\n                    <i>via<\/i>\n                    fibroblast growth factor 21"],"prefix":"10.1039","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3674-6279","authenticated-orcid":false,"given":"Siqi","family":"Yang","sequence":"first","affiliation":[{"name":"School of Food Science and Technology, Jiangnan University and State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayue","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi 214122, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin-Bin","family":"Li","sequence":"additional","affiliation":[{"name":"School of Food Science and Technology, Jiangnan University and State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjie","family":"Liang","sequence":"additional","affiliation":[{"name":"School of Food Science and Technology, Jiangnan University and State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimin","family":"Zou","sequence":"additional","affiliation":[{"name":"School of Food Science and Technology, Jiangnan University and State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilong","family":"Pan","sequence":"additional","affiliation":[{"name":"MOE Medical Basic Research Innovation Center for Gut Microbiota and Chronic Diseases, School of Medicine, Jiangnan University, Wuxi, Jiangsu 214122, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Food Science and Technology, Jiangnan University and State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China"},{"name":"MOE Medical Basic Research Innovation Center for Gut Microbiota and Chronic Diseases, School of Medicine, Jiangnan University, Wuxi, Jiangsu 214122, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D5FO00832H\/cit1\/1","doi-asserted-by":"crossref","first-page":"607","DOI":"10.12688\/f1000research.12852.1","volume":"7","author":"Pham","year":"2018","journal-title":"F1000Research"},{"key":"D5FO00832H\/cit2\/1","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0140-6736(20)31318-0","volume":"396","author":"Beyer","year":"2020","journal-title":"Lancet"},{"key":"D5FO00832H\/cit3\/1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/BF01223154","volume":"16","author":"Kalk","year":"1979","journal-title":"Diabetologia"},{"key":"D5FO00832H\/cit4\/1","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/S0140-6736(10)61852-1","volume":"377","author":"Braganza","year":"2011","journal-title":"Lancet"},{"key":"D5FO00832H\/cit5\/1","doi-asserted-by":"crossref","first-page":"CR583","DOI":"10.12659\/MSM.881985","volume":"17","author":"Mokrowiecka","year":"2011","journal-title":"Med. Sci. Monit."},{"key":"D5FO00832H\/cit6\/1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.dld.2004.10.007","volume":"37","author":"Pezzilli","year":"2005","journal-title":"Dig. Liver Dis."},{"key":"D5FO00832H\/cit7\/1","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.4240\/wjgs.v15.i8.1574","volume":"15","author":"Walia","year":"2023","journal-title":"World J. Gastrointest. Surg."},{"key":"D5FO00832H\/cit8\/1","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1056\/NEJM199305203282001","volume":"328","author":"Lowenfels","year":"1993","journal-title":"N. Engl. J. Med."},{"key":"D5FO00832H\/cit9\/1","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1001\/jama.2019.19411","volume":"322","author":"Singh","year":"2019","journal-title":"J. Am. Med. Assoc."},{"key":"D5FO00832H\/cit10\/1","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1007\/s10620-017-4518-x","volume":"62","author":"Ramsey","year":"2017","journal-title":"Dig. Dis Sci."},{"key":"D5FO00832H\/cit11\/1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/s41575-019-0242-7","volume":"17","author":"Thomas","year":"2020","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"D5FO00832H\/cit12\/1","doi-asserted-by":"crossref","first-page":"464","DOI":"10.21037\/atm.2019.08.18","volume":"7","author":"Han","year":"2019","journal-title":"Ann. Transl. Med."},{"key":"D5FO00832H\/cit13\/1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1620\/tjem.244.113","volume":"244","author":"Hamada","year":"2018","journal-title":"Tohoku J. Exp. Med."},{"key":"D5FO00832H\/cit14\/1","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1177\/2050640616630117","volume":"4","author":"Capurso","year":"2016","journal-title":"United Eur. Gastroenterol. J."},{"key":"D5FO00832H\/cit15\/1","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1038\/s41401-020-00532-0","volume":"42","author":"Pan","year":"2021","journal-title":"Acta Pharmacol. Sin."},{"key":"D5FO00832H\/cit16\/1","doi-asserted-by":"crossref","first-page":"886","DOI":"10.3390\/nu11040886","volume":"11","author":"Vitellio","year":"2019","journal-title":"Nutrients"},{"key":"D5FO00832H\/cit17\/1","doi-asserted-by":"crossref","first-page":"12144","DOI":"10.1039\/D2FO01900K","volume":"13","author":"Gu","year":"2022","journal-title":"Food Funct."},{"key":"D5FO00832H\/cit18\/1","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1136\/gutjnl-2018-316226","volume":"68","author":"Riehl","year":"2019","journal-title":"Gut"},{"key":"D5FO00832H\/cit19\/1","doi-asserted-by":"crossref","first-page":"3919","DOI":"10.1039\/D0FO02879G","volume":"12","author":"Zheng","year":"2021","journal-title":"Food Funct."},{"key":"D5FO00832H\/cit20\/1","doi-asserted-by":"crossref","first-page":"150","DOI":"10.4168\/aair.2012.4.3.150","volume":"4","author":"Jang","year":"2012","journal-title":"Allergy, Asthma Immunol. Res."},{"key":"D5FO00832H\/cit21\/1","doi-asserted-by":"crossref","first-page":"10784","DOI":"10.1039\/D3FO03321J","volume":"14","author":"Shi","year":"2023","journal-title":"Food Funct."},{"key":"D5FO00832H\/cit22\/1","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1038\/ismej.2015.151","volume":"10","author":"Canani","year":"2016","journal-title":"ISME J."},{"key":"D5FO00832H\/cit23\/1","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1007\/s12602-023-10167-2","volume":"17","author":"Vasconcelos","year":"2023","journal-title":"Probiotics Antimicrob. Proteins"},{"key":"D5FO00832H\/cit24\/1","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.1002\/hep.30975","volume":"71","author":"Liu","year":"2020","journal-title":"Hepatology"},{"key":"D5FO00832H\/cit25\/1","doi-asserted-by":"crossref","first-page":"106350","DOI":"10.1016\/j.phrs.2022.106350","volume":"182","author":"Zhao","year":"2022","journal-title":"Pharmacol. Res."},{"key":"D5FO00832H\/cit26\/1","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/j.1365-2567.2007.02792.x","volume":"124","author":"Seow","year":"2008","journal-title":"Immunology"},{"key":"D5FO00832H\/cit27\/1","doi-asserted-by":"crossref","first-page":"117903","DOI":"10.1016\/j.biopha.2025.117903","volume":"184","author":"Avagliano","year":"2025","journal-title":"Biomed. Pharmacother."},{"key":"D5FO00832H\/cit28\/1","doi-asserted-by":"crossref","first-page":"203","DOI":"10.2144\/btn-2022-0120","volume":"74","author":"Zhang","year":"2023","journal-title":"BioTechniques"},{"key":"D5FO00832H\/cit29\/1","doi-asserted-by":"crossref","first-page":"4202","DOI":"10.1016\/j.apsb.2023.08.002","volume":"13","author":"Pan","year":"2023","journal-title":"Acta Pharm. Sin. B"},{"key":"D5FO00832H\/cit30\/1","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1053\/j.gastro.2022.03.054","volume":"163","author":"Nagata","year":"2022","journal-title":"Gastroenterology"},{"key":"D5FO00832H\/cit31\/1","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.ijbiomac.2016.09.029","volume":"93","author":"Li","year":"2016","journal-title":"Int. J. Biol. Macromol."},{"key":"D5FO00832H\/cit32\/1","doi-asserted-by":"crossref","first-page":"4457","DOI":"10.1038\/s41467-020-18262-6","volume":"11","author":"Yang","year":"2020","journal-title":"Nat. Commun."},{"key":"D5FO00832H\/cit33\/1","doi-asserted-by":"crossref","first-page":"797","DOI":"10.2337\/db11-0846","volume":"61","author":"Li","year":"2012","journal-title":"Diabetes"},{"key":"D5FO00832H\/cit34\/1","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1053\/j.gastro.2019.07.030","volume":"157","author":"Luo","year":"2019","journal-title":"Gastroenterology"},{"key":"D5FO00832H\/cit35\/1","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.pan.2020.02.007","volume":"20","author":"Garcia Garcia de Paredes","year":"2020","journal-title":"Pancreatology"},{"key":"D5FO00832H\/cit36\/1","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1080\/19490976.2020.1770042","volume":"11","author":"Li","year":"2020","journal-title":"Gut Microbes"},{"key":"D5FO00832H\/cit37\/1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.7869\/tg.314","volume":"37","author":"Sharma","year":"2016","journal-title":"Trop. Gastroenterol."},{"key":"D5FO00832H\/cit38\/1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.pan.2019.11.013","volume":"20","author":"Zhou","year":"2020","journal-title":"Pancreatology"},{"key":"D5FO00832H\/cit39\/1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1097\/MPA.0000000000001708","volume":"50","author":"Vajravelu","year":"2021","journal-title":"Pancreas"},{"key":"D5FO00832H\/cit40\/1","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1097\/MPA.0000000000000726","volume":"46","author":"Rogers","year":"2017","journal-title":"Pancreas"},{"key":"D5FO00832H\/cit41\/1","doi-asserted-by":"crossref","first-page":"107272","DOI":"10.1016\/j.intimp.2020.107272","volume":"91","author":"Tang","year":"2021","journal-title":"Int. Immunopharmacol."},{"key":"D5FO00832H\/cit42\/1","doi-asserted-by":"crossref","first-page":"2346","DOI":"10.1111\/jcmm.13526","volume":"22","author":"Sun","year":"2018","journal-title":"J. Cell. Mol. Med."},{"key":"D5FO00832H\/cit43\/1","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1177\/2050640618804444","volume":"6","author":"Rau","year":"2018","journal-title":"United Eur. Gastroenterol. J."},{"key":"D5FO00832H\/cit44\/1","doi-asserted-by":"crossref","first-page":"e00232","DOI":"10.14309\/ctg.0000000000000232","volume":"11","author":"Frost","year":"2020","journal-title":"Clin. Transl. Gastroenterol."},{"key":"D5FO00832H\/cit45\/1","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.jnutbio.2010.07.009","volume":"22","author":"Vinolo","year":"2011","journal-title":"J. Nutr. Biochem."},{"key":"D5FO00832H\/cit46\/1","first-page":"L956","volume":"286","author":"Park","year":"2004","journal-title":"Am. J. Physiol.: Lung Cell. Mol. Physiol."},{"key":"D5FO00832H\/cit47\/1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.intimp.2006.08.015","volume":"7","author":"Park","year":"2007","journal-title":"Int. Immunopharmacol."},{"key":"D5FO00832H\/cit48\/1","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/jbt.21698","volume":"29","author":"Kanika","year":"2015","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"D5FO00832H\/cit49\/1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/gb-2001-2-3-reviews3005","volume":"2","author":"Ornitz","year":"2001","journal-title":"Genome Biol."},{"key":"D5FO00832H\/cit50\/1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.tem.2024.02.001","volume":"35","author":"Chui","year":"2024","journal-title":"Trends Endocrinol. Metab."},{"key":"D5FO00832H\/cit51\/1","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1164\/rccm.202311-2021OC","volume":"211","author":"Ghanem","year":"2025","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"D5FO00832H\/cit52\/1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.15252\/emmm.201708791","volume":"10","author":"Jimenez","year":"2018","journal-title":"EMBO Mol. Med."},{"key":"D5FO00832H\/cit53\/1","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.cbi.2018.07.008","volume":"292","author":"Hu","year":"2018","journal-title":"Chem.-Biol. Interact."},{"key":"D5FO00832H\/cit54\/1","doi-asserted-by":"crossref","first-page":"461","DOI":"10.3389\/fphar.2017.00461","volume":"8","author":"Walton","year":"2017","journal-title":"Front. Pharmacol."},{"key":"D5FO00832H\/cit55\/1","doi-asserted-by":"crossref","first-page":"110413","DOI":"10.1016\/j.biopha.2020.110413","volume":"129","author":"Chen","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"D5FO00832H\/cit56\/1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3349\/ymj.2019.60.1.79","volume":"60","author":"Liu","year":"2019","journal-title":"Yonsei Med. J."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/FO\/D5FO00832H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:27:02Z","timestamp":1782880022000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/16\/12\/5076-5087\/893012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":56,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,6,16]]}},"URL":"https:\/\/doi.org\/10.1039\/d5fo00832h","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}