{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T06:50:51Z","timestamp":1787986251081,"version":"build-2784847793"},"reference-count":68,"publisher":"Royal Society of Chemistry (RSC)","issue":"1","license":[{"start":{"date-parts":[[2026,12,11]],"date-time":"2026-12-11T00:00:00Z","timestamp":1796947200000},"content-version":"am","delay-in-days":344,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82460699"],"award-info":[{"award-number":["82460699"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    Oyster hydrolysate produced\n                    <jats:italic>via<\/jats:italic>\n                    dynamic enzymolysis membrane reactor rich in small peptides, taurine and zinc alleviates male sexual dysfunction by reducing testicular oxidative stress, improving renal function and restoring sex hormone levels.\n                  <\/jats:p>","DOI":"10.1039\/d5fo03860j","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T13:21:48Z","timestamp":1765459308000},"page":"531-549","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Oyster hydrolysate\n                    <i>via<\/i>\n                    dynamic enzymolysis ameliorates male sexual dysfunction in mice"],"prefix":"10.1039","volume":"17","author":[{"given":"Chunli","family":"Xu","sequence":"first","affiliation":[{"name":"Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhong","family":"Huang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junran","family":"Yin","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengfei","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongyu","family":"An","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiming","family":"Deng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2175-3154","authenticated-orcid":false,"given":"Guijin","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D5FO03860J\/cit1\/1","doi-asserted-by":"crossref","first-page":"108585","DOI":"10.1016\/j.biopha.2019.01.046","volume":"112","author":"Chen","year":"2019","journal-title":"Biomed. Pharmacother."},{"key":"D5FO03860J\/cit2\/1","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.fertnstert.2015.11.011","volume":"105","author":"Eisenberg","year":"2016","journal-title":"Fertil. Steril."},{"key":"D5FO03860J\/cit3\/1","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/S1472-6483(10)60530-5","volume":"15","author":"Giwercmanz","year":"2007","journal-title":"Reprod. BioMed. Online"},{"key":"D5FO03860J\/cit4\/1","doi-asserted-by":"crossref","first-page":"108898","DOI":"10.1016\/j.envint.2024.108898","volume":"190","author":"Li","year":"2024","journal-title":"Environ. Int."},{"key":"D5FO03860J\/cit5\/1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0140-6736(20)32667-2","volume":"397","author":"Agarwal","year":"2021","journal-title":"Lancet"},{"key":"D5FO03860J\/cit6\/1","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.fertnstert.2021.07.1202","volume":"116","author":"Velez","year":"2021","journal-title":"Fertil. Steril."},{"key":"D5FO03860J\/cit7\/1","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1111\/j.1743-6109.2011.02582.x","volume":"9","author":"Tan","year":"2012","journal-title":"J. Sex. Med."},{"key":"D5FO03860J\/cit8\/1","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1089\/jwh.2009.1800","volume":"19","author":"Schnatz","year":"2010","journal-title":"J. Women's Health"},{"key":"D5FO03860J\/cit9\/1","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1007\/s12015-023-10577-3","volume":"19","author":"Adriansyah","year":"2023","journal-title":"Stem Cell Rev. Rep."},{"key":"D5FO03860J\/cit10\/1","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.3390\/cells11101711","volume":"11","author":"Assidi","year":"2022","journal-title":"Cells"},{"key":"D5FO03860J\/cit11\/1","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.3390\/medicina59101835","volume":"59","author":"Kaltsas","year":"2023","journal-title":"Medicina"},{"key":"D5FO03860J\/cit12\/1","doi-asserted-by":"crossref","first-page":"874","DOI":"10.3390\/antiox10060874","volume":"10","author":"Salvio","year":"2021","journal-title":"Antioxidants"},{"key":"D5FO03860J\/cit13\/1","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1007\/s11255-022-03237-x","volume":"54","author":"Zhou","year":"2022","journal-title":"Int. Urol. Nephrol."},{"key":"D5FO03860J\/cit14\/1","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1111\/andr.13388","volume":"11","author":"Huijben","year":"2023","journal-title":"Andrology"},{"key":"D5FO03860J\/cit15\/1","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0531-5565(99)00003-0","volume":"34","author":"Glossmann","year":"1999","journal-title":"Exp. Gerontol."},{"key":"D5FO03860J\/cit16\/1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/s41443-018-0067-x","volume":"31","author":"Scherzer","year":"2019","journal-title":"Int. J. Impotence Res."},{"key":"D5FO03860J\/cit17\/1","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.sxmr.2018.10.001","volume":"7","author":"Wheeler","year":"2019","journal-title":"Sex. Med. Rev."},{"key":"D5FO03860J\/cit18\/1","doi-asserted-by":"crossref","first-page":"8659","DOI":"10.1039\/D0FO01713B","volume":"11","author":"Xiao","year":"2020","journal-title":"Food Funct."},{"key":"D5FO03860J\/cit19\/1","doi-asserted-by":"crossref","first-page":"6577","DOI":"10.1039\/C8FO01879K","volume":"9","author":"Miao","year":"2018","journal-title":"Food Funct."},{"key":"D5FO03860J\/cit20\/1","doi-asserted-by":"crossref","first-page":"566","DOI":"10.3390\/md19100566","volume":"19","author":"Zhang","year":"2021","journal-title":"Mar. Drugs"},{"key":"D5FO03860J\/cit21\/1","first-page":"13468","volume":"44","author":"Li","year":"2020","journal-title":"J. Food Biochem."},{"key":"D5FO03860J\/cit22\/1","doi-asserted-by":"crossref","first-page":"6470","DOI":"10.1002\/fsn3.3589","volume":"11","author":"Yan","year":"2023","journal-title":"Food Sci. Nutr."},{"key":"D5FO03860J\/cit23\/1","doi-asserted-by":"crossref","first-page":"104700","DOI":"10.1016\/j.jff.2021.104700","volume":"86","author":"Luo","year":"2021","journal-title":"J. Funct. Foods"},{"key":"D5FO03860J\/cit24\/1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.foodchem.2017.10.055","volume":"267","author":"Baldassarre","year":"2018","journal-title":"Food Chem."},{"key":"D5FO03860J\/cit25\/1","doi-asserted-by":"crossref","first-page":"108729","DOI":"10.1016\/j.cep.2021.108729","volume":"180","author":"Sitanggang","year":"2022","journal-title":"Chem. Eng. Process."},{"key":"D5FO03860J\/cit26\/1","doi-asserted-by":"crossref","first-page":"116840","DOI":"10.1016\/j.seppur.2020.116840","volume":"243","author":"Su","year":"2020","journal-title":"Sep. Purif. Technol."},{"key":"D5FO03860J\/cit27\/1","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.4155\/bio-2016-0111","volume":"8","author":"Fuertig","year":"2016","journal-title":"Bioanalysis"},{"key":"D5FO03860J\/cit28\/1","doi-asserted-by":"crossref","first-page":"113018","DOI":"10.1016\/j.jpba.2019.113018","volume":"180","author":"Vir\u00e1g","year":"2020","journal-title":"J. Pharm. Biomed. Anal."},{"key":"D5FO03860J\/cit29\/1","doi-asserted-by":"crossref","first-page":"101956","DOI":"10.1016\/j.fbio.2022.101956","volume":"49","author":"An","year":"2022","journal-title":"Food Biosci."},{"key":"D5FO03860J\/cit30\/1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.3390\/md19050270","volume":"19","author":"Fang","year":"2021","journal-title":"Mar. Drugs"},{"key":"D5FO03860J\/cit31\/1","doi-asserted-by":"crossref","first-page":"111359","DOI":"10.1016\/j.foodres.2022.111359","volume":"157","author":"Xia","year":"2022","journal-title":"Food Res. Int."},{"key":"D5FO03860J\/cit32\/1","doi-asserted-by":"crossref","first-page":"106230","DOI":"10.1016\/j.fbio.2025.106230","volume":"66","author":"Chauhan","year":"2025","journal-title":"Food Biosci."},{"key":"D5FO03860J\/cit33\/1","doi-asserted-by":"crossref","first-page":"100504","DOI":"10.1016\/j.hermed.2021.100504","volume":"32","author":"Kim","year":"2022","journal-title":"J. Herb. Med."},{"key":"D5FO03860J\/cit34\/1","first-page":"101868","volume":"40","author":"Jin","year":"2024","journal-title":"Biochem. Biophys. Rep."},{"key":"D5FO03860J\/cit35\/1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.matbio.2004.06.001","volume":"23","author":"Van Der Slot","year":"2004","journal-title":"Matrix Biol."},{"key":"D5FO03860J\/cit36\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/301982","volume":"2013","author":"Sung","year":"2013","journal-title":"Oxid. Med. Cell. Longevity"},{"key":"D5FO03860J\/cit37\/1","doi-asserted-by":"crossref","first-page":"9491","DOI":"10.1073\/pnas.0402961101","volume":"101","author":"Zhang","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D5FO03860J\/cit38\/1","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1111\/jcmm.17837","volume":"27","author":"Li","year":"2023","journal-title":"J. Cell. Mol. Med."},{"key":"D5FO03860J\/cit39\/1","doi-asserted-by":"crossref","first-page":"5572","DOI":"10.1002\/fsn3.4213","volume":"12","author":"Huang","year":"2024","journal-title":"Food Sci. Nutr."},{"key":"D5FO03860J\/cit40\/1","doi-asserted-by":"crossref","first-page":"3732","DOI":"10.3390\/jcm11133732","volume":"11","author":"Khalid","year":"2022","journal-title":"J. Clin. Med."},{"key":"D5FO03860J\/cit41\/1","first-page":"100175","volume":"12","author":"Fang","year":"2021","journal-title":"Food Chem.: X"},{"key":"D5FO03860J\/cit42\/1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.procbio.2022.12.019","volume":"125","author":"Oh","year":"2023","journal-title":"Process Biochem."},{"key":"D5FO03860J\/cit43\/1","doi-asserted-by":"crossref","first-page":"111402","DOI":"10.1016\/j.foodres.2022.111402","volume":"157","author":"Wang","year":"2022","journal-title":"Food Res. Int."},{"key":"D5FO03860J\/cit44\/1","doi-asserted-by":"crossref","first-page":"11702","DOI":"10.1021\/acs.jafc.0c02476","volume":"68","author":"Gao","year":"2020","journal-title":"J. Agric. Food Chem."},{"key":"D5FO03860J\/cit45\/1","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.reprotox.2021.01.013","volume":"101","author":"Oyovwi","year":"2021","journal-title":"Reprod. Toxicol."},{"key":"D5FO03860J\/cit46\/1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.biopha.2017.10.095","volume":"97","author":"Adedara","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"D5FO03860J\/cit47\/1","doi-asserted-by":"crossref","first-page":"139494","DOI":"10.1016\/j.ijbiomac.2025.139494","volume":"295","author":"Feng","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"D5FO03860J\/cit48\/1","doi-asserted-by":"crossref","first-page":"8991","DOI":"10.3390\/ijms25168991","volume":"25","author":"Mar\u00edn De Jes\u00fas","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"D5FO03860J\/cit49\/1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.foodchem.2017.10.087","volume":"245","author":"Chalamaiah","year":"2018","journal-title":"Food Chem."},{"key":"D5FO03860J\/cit50\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.etap.2017.11.002","volume":"57","author":"He","year":"2018","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"D5FO03860J\/cit51\/1","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.cmet.2020.06.010","volume":"32","author":"Kelly","year":"2020","journal-title":"Cell Metab."},{"key":"D5FO03860J\/cit52\/1","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.anireprosci.2016.08.003","volume":"172","author":"Dong","year":"2016","journal-title":"Anim. Reprod. Sci."},{"key":"D5FO03860J\/cit53\/1","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.theriogenology.2018.12.024","volume":"126","author":"Zhang","year":"2019","journal-title":"Theriogenology"},{"key":"D5FO03860J\/cit54\/1","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1016\/j.fct.2004.05.001","volume":"42","author":"El-Demerdash","year":"2004","journal-title":"Food Chem. Toxicol."},{"key":"D5FO03860J\/cit55\/1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3390\/antiox9020111","volume":"9","author":"Aitken","year":"2020","journal-title":"Antioxidants"},{"key":"D5FO03860J\/cit56\/1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.tips.2022.12.003","volume":"44","author":"Dinkova-Kostova","year":"2023","journal-title":"Trends Pharmacol. Sci."},{"key":"D5FO03860J\/cit57\/1","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.3390\/cells12182292","volume":"12","author":"Alnajem","year":"2023","journal-title":"Cells"},{"key":"D5FO03860J\/cit58\/1","doi-asserted-by":"crossref","first-page":"153057","DOI":"10.1016\/j.phymed.2019.153057","volume":"64","author":"Ma","year":"2019","journal-title":"Phytomedicine"},{"key":"D5FO03860J\/cit59\/1","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.biopha.2017.01.066","volume":"88","author":"Sun","year":"2017","journal-title":"Biomed. Pharmacother."},{"key":"D5FO03860J\/cit60\/1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.3390\/biology14020161","volume":"14","author":"Abdelrahman","year":"2025","journal-title":"Biology"},{"key":"D5FO03860J\/cit61\/1","doi-asserted-by":"crossref","first-page":"2545983","DOI":"10.1080\/0886022X.2025.2545983","volume":"47","author":"Wang","year":"2025","journal-title":"Renal Failure"},{"key":"D5FO03860J\/cit62\/1","doi-asserted-by":"crossref","first-page":"1457780","DOI":"10.3389\/fphar.2024.1457780","volume":"15","author":"Chen","year":"2024","journal-title":"Front. Pharmacol."},{"key":"D5FO03860J\/cit63\/1","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1210\/endocr\/bqae116","volume":"165","author":"Schultz","year":"2024","journal-title":"Endocrinology"},{"key":"D5FO03860J\/cit64\/1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.21037\/tau.2019.11.16","volume":"9","author":"Krzastek","year":"2020","journal-title":"Transl. Androl. Urol."},{"key":"D5FO03860J\/cit65\/1","doi-asserted-by":"crossref","first-page":"10376","DOI":"10.3390\/ijms221910376","volume":"22","author":"Melis","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"D5FO03860J\/cit66\/1","doi-asserted-by":"crossref","first-page":"117886","DOI":"10.1016\/j.lwt.2025.117886","volume":"224","author":"Han","year":"2025","journal-title":"LWT"},{"key":"D5FO03860J\/cit67\/1","doi-asserted-by":"crossref","first-page":"103722","DOI":"10.1016\/j.fbio.2024.103722","volume":"58","author":"Wang","year":"2024","journal-title":"Food Biosci."},{"key":"D5FO03860J\/cit68\/1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jare.2025.02.005","volume":"78","author":"Yang","year":"2025","journal-title":"J. Adv. Res."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2026\/FO\/D5FO03860J","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T17:25:09Z","timestamp":1768238709000},"score":1,"resource":{"primary":{"URL":"https:\/\/xlink.rsc.org\/?DOI=D5FO03860J"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":68,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,12]]}},"URL":"https:\/\/doi.org\/10.1039\/d5fo03860j","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}