{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T02:42:39Z","timestamp":1790044959985,"version":"4.0.1"},"reference-count":133,"publisher":"Royal Society of Chemistry (RSC)","issue":"5","license":[{"start":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T00:00:00Z","timestamp":1771804800000},"content-version":"vor","delay-in-days":53,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001872","name":"Centre for Industrial Technological Development","doi-asserted-by":"publisher","award":["MIG-20201012"],"award-info":[{"award-number":["MIG-20201012"]}],"id":[{"id":"10.13039\/501100001872","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["PID2021-127812OB-I00"],"award-info":[{"award-number":["PID2021-127812OB-I00"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002704","name":"Fundaci\u00f3n Cient\u00edfica Asociaci\u00f3n Espa\u00f1ola Contra el C\u00e1ncer","doi-asserted-by":"publisher","award":["PRDAS233973MCAL"],"award-info":[{"award-number":["PRDAS233973MCAL"]}],"id":[{"id":"10.13039\/501100002704","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>A functional meat containing a synergistic combination of nutraceuticals reduced colitis-associated colorectal tumor burden in rats. Tumor suppression was associated with reduced inflammation and modulation of the gut microbiota.<\/jats:p>","DOI":"10.1039\/d5fo04442a","type":"journal-article","created":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T08:56:49Z","timestamp":1771837009000},"page":"2457-2475","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevention of colorectal cancer and modulation of murine gut microbiota using functional meats"],"prefix":"10.1039","volume":"17","author":[{"given":"Patrick L.","family":"McAlpine","sequence":"first","affiliation":[{"name":"Research Group BIONUC (Biotechnology of Nutraceuticals and Bioactive Compounds), Departamento de Biolog\u00eda Funcional, \u00c1rea de Microbiolog\u00eda, Universidad de Oviedo, 33006, Oviedo, Spain"},{"name":"IUOPA (Cancer Research Institute of the Principality of Asturias), 33006 Oviedo, Spain"},{"name":"ISPA (Health Research Institute of the Principality of Asturias), 33011 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Borondo","sequence":"additional","affiliation":[{"name":"AGrowingData, 04002 Almer\u00eda, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar","family":"Grande","sequence":"additional","affiliation":[{"name":"AGrowingData, 04002 Almer\u00eda, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia","family":"Gil-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"DMC Research Center, 18620 Alhend\u00edn, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Falc\u00f3n-Pi\u00f1eiro","sequence":"additional","affiliation":[{"name":"DMC Research Center, 18620 Alhend\u00edn, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Ba\u00f1os","sequence":"additional","affiliation":[{"name":"DMC Research Center, 18620 Alhend\u00edn, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estefan\u00eda","family":"Crespo Losada","sequence":"additional","affiliation":[{"name":"BDI-Biotechnology Development for Industry SL, 47151 Boecillo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco M.","family":"Reyes-Sosa","sequence":"additional","affiliation":[{"name":"BDI-Biotechnology Development for Industry SL, 47151 Boecillo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Caro Ruiz","sequence":"additional","affiliation":[{"name":"FUDin, 26315 Ales\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Uribe Oyarbide","sequence":"additional","affiliation":[{"name":"FUDin, 26315 Ales\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"\u00c1lvarez Gil","sequence":"additional","affiliation":[{"name":"Neoalgae, 33211 Gij\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas Fidel","family":"Delgado Ramallo","sequence":"additional","affiliation":[{"name":"Neoalgae, 33211 Gij\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Mart\u00edn","family":"Atienza","sequence":"additional","affiliation":[{"name":"BTSA, 28805 Alcal\u00e1 de Henares, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Garc\u00eda Migu\u00e9lez","sequence":"additional","affiliation":[{"name":"BTSA, 28805 Alcal\u00e1 de Henares, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Santamar\u00eda-Martos","sequence":"additional","affiliation":[{"name":"ARGAL, 25424 Miralcamp, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaume Palau","family":"Clivill\u00e9","sequence":"additional","affiliation":[{"name":"ARGAL, 25424 Miralcamp, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio J.","family":"Villar","sequence":"additional","affiliation":[{"name":"Research Group BIONUC (Biotechnology of Nutraceuticals and Bioactive Compounds), Departamento de Biolog\u00eda Funcional, \u00c1rea de Microbiolog\u00eda, Universidad de Oviedo, 33006, Oviedo, Spain"},{"name":"IUOPA (Cancer Research Institute of the Principality of Asturias), 33006 Oviedo, Spain"},{"name":"ISPA (Health Research Institute of the Principality of Asturias), 33011 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Research Group BIONUC (Biotechnology of Nutraceuticals and Bioactive Compounds), Departamento de Biolog\u00eda Funcional, \u00c1rea de Microbiolog\u00eda, Universidad de Oviedo, 33006, Oviedo, Spain"},{"name":"IUOPA (Cancer Research Institute of the Principality of Asturias), 33006 Oviedo, Spain"},{"name":"ISPA (Health Research Institute of the Principality of Asturias), 33011 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6680-6723","authenticated-orcid":false,"given":"Felipe","family":"Lomb\u00f3","sequence":"additional","affiliation":[{"name":"Research Group BIONUC (Biotechnology of Nutraceuticals and Bioactive Compounds), Departamento de Biolog\u00eda Funcional, \u00c1rea de Microbiolog\u00eda, Universidad de Oviedo, 33006, Oviedo, Spain"},{"name":"IUOPA (Cancer Research Institute of the Principality of Asturias), 33006 Oviedo, Spain"},{"name":"ISPA (Health Research Institute of the Principality of Asturias), 33011 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D5FO04442A\/cit1\/1","volume-title":"World Cancer Report: Cancer research for cancer prevention","author":"Wild","year":"2020","unstructured":"C. P.Wild ,  E.Weiderpass  and  B. W.Stewart ,  World Cancer Report: Cancer research for cancer prevention ,  International Agency for Research on Cancer ,  Lyon ,  2020"},{"key":"D5FO04442A\/cit2\/1","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1308\/rcsann.2024.0024","volume":"106","author":"Sadien","year":"2024","journal-title":"Ann. R. Coll. Surg. Engl."},{"key":"D5FO04442A\/cit3\/1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1093\/nutrit\/nux012","volume":"75","author":"Grosso","year":"2017","journal-title":"Nutr. Rev."},{"key":"D5FO04442A\/cit4\/1","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.3390\/nu9101063","volume":"9","author":"Schwingshackl","year":"2017","journal-title":"Nutrients"},{"key":"D5FO04442A\/cit5\/1","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1093\/jn\/nxz268","volume":"150","author":"Clinton","year":"2020","journal-title":"J. Nutr."},{"key":"D5FO04442A\/cit6\/1","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1016\/S1470-2045(15)00444-1","volume":"16","author":"Bouvard","year":"2015","journal-title":"Lancet Oncol."},{"key":"D5FO04442A\/cit7\/1","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1002\/ijc.32689","volume":"146","author":"Deoula","year":"2020","journal-title":"Int. J. Cancer"},{"key":"D5FO04442A\/cit8\/1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.meatsci.2015.05.012","volume":"109","author":"Sans","year":"2015","journal-title":"Meat Sci."},{"key":"D5FO04442A\/cit9\/1","doi-asserted-by":"crossref","first-page":"14783","DOI":"10.1038\/s41598-019-51437-w","volume":"9","author":"Fern\u00e1ndez","year":"2019","journal-title":"Sci. Rep."},{"key":"D5FO04442A\/cit10\/1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.3390\/genes9030133","volume":"9","author":"Fern\u00e1ndez","year":"2018","journal-title":"Genes"},{"key":"D5FO04442A\/cit11\/1","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1186\/s12885-021-09054-2","volume":"21","author":"Rebersek","year":"2021","journal-title":"BMC Cancer"},{"key":"D5FO04442A\/cit12\/1","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1136\/gutjnl-2020-322260","volume":"69","author":"Paone","year":"2020","journal-title":"Gut"},{"key":"D5FO04442A\/cit13\/1","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1002\/ags3.12517","volume":"6","author":"Zhang","year":"2022","journal-title":"Ann. Gastroenterol. Surg."},{"key":"D5FO04442A\/cit14\/1","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.jff.2016.06.032","volume":"25","author":"Fern\u00e1ndez","year":"2016","journal-title":"J. Funct. Foods"},{"key":"D5FO04442A\/cit15\/1","first-page":"102680","volume":"29","author":"Yang","year":"2025","journal-title":"Food Chem.: X"},{"key":"D5FO04442A\/cit16\/1","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.lwt.2010.05.020","volume":"44","author":"Hayes","year":"2011","journal-title":"LWT \u2013 Food Sci. Technol."},{"key":"D5FO04442A\/cit17\/1","doi-asserted-by":"crossref","first-page":"128095","DOI":"10.1016\/j.foodchem.2020.128095","volume":"340","author":"Pintado","year":"2021","journal-title":"Food Chem."},{"key":"D5FO04442A\/cit18\/1","volume-title":"Encapsulation in Food Processing and Fermentation","author":"Staji\u0107","year":"2022","unstructured":"S.Staji\u0107  and  D.Vasilev ,  Encapsulation of Meat Product Ingredients and Influence on Product Quality , in  Encapsulation in Food Processing and Fermentation , ed.  S. Levi\u0107 ,  V. Nedovi\u0107  and  B. Bugarski ,  Taylor & Francis Group ,  Boca Raton , 1st edn,  2022"},{"key":"D5FO04442A\/cit19\/1","first-page":"81","volume-title":"Encyclopedia of Dietary Supplements","author":"Johnson","year":"2004","unstructured":"E. J.Johnson  and  R. M.Russell ,  Beta-Carotene , in  Encyclopedia of Dietary Supplements , ed.  P. Coates ,  M. Blackman ,  G. M. Cragg ,  M. A. Levine ,  J. Moss  and  J. D. White ,  USDA ,  NY ,  2004 , pp.  81\u201387"},{"key":"D5FO04442A\/cit20\/1","doi-asserted-by":"crossref","first-page":"128","DOI":"10.3390\/md12010128","volume":"12","author":"Ambati","year":"2014","journal-title":"Mar. Drugs"},{"key":"D5FO04442A\/cit21\/1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.4162\/nrp.2022.16.2.161","volume":"16","author":"Lee","year":"2022","journal-title":"Nutr. Res. Pract."},{"key":"D5FO04442A\/cit22\/1","doi-asserted-by":"crossref","first-page":"108402","DOI":"10.1016\/j.jnutbio.2020.108402","volume":"82","author":"Lee","year":"2020","journal-title":"J. Nutr. Biochem."},{"key":"D5FO04442A\/cit23\/1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s10637-009-9342-5","volume":"29","author":"Nagendraprabhu","year":"2011","journal-title":"Invest. New Drugs"},{"key":"D5FO04442A\/cit24\/1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1472-8206.2009.00669.x","volume":"23","author":"Prabhu","year":"2009","journal-title":"Fundam. Clin. Pharmacol."},{"key":"D5FO04442A\/cit25\/1","doi-asserted-by":"crossref","first-page":"9457","DOI":"10.1038\/s41598-019-45924-3","volume":"9","author":"Kim","year":"2019","journal-title":"Sci. Rep."},{"key":"D5FO04442A\/cit26\/1","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1186\/s12876-014-0212-z","volume":"14","author":"Kochi","year":"2014","journal-title":"BMC Gastroenterol."},{"key":"D5FO04442A\/cit27\/1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.cbi.2011.05.006","volume":"193","author":"Yasui","year":"2011","journal-title":"Chem.-Biol. Interact."},{"key":"D5FO04442A\/cit28\/1","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/ptr.7295","volume":"36","author":"Yuan","year":"2022","journal-title":"Phytother. Res."},{"key":"D5FO04442A\/cit29\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.plefa.2017.08.001","volume":"124","author":"Echeverr\u00eda","year":"2017","journal-title":"Prostaglandins, Leukotrienes Essent. Fatty Acids"},{"key":"D5FO04442A\/cit30\/1","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1093\/carcin\/18.10.1937","volume":"18","author":"Takahashi","year":"1997","journal-title":"Carcinogenesis"},{"key":"D5FO04442A\/cit31\/1","doi-asserted-by":"crossref","first-page":"4611","DOI":"10.1038\/onc.2015.523","volume":"35","author":"Fluckiger","year":"2016","journal-title":"Oncogene"},{"key":"D5FO04442A\/cit32\/1","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1080\/01635581.2012.665563","volume":"64","author":"Rosa","year":"2012","journal-title":"Nutr. Cancer"},{"key":"D5FO04442A\/cit33\/1","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1080\/01635581.2013.785009","volume":"65","author":"Rao","year":"2013","journal-title":"Nutr. Cancer"},{"key":"D5FO04442A\/cit34\/1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1136\/gut.2010.233718","volume":"61","author":"Cockbain","year":"2012","journal-title":"Gut"},{"key":"D5FO04442A\/cit35\/1","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1093\/toxres\/tfaa046","volume":"9","author":"Gonz\u00e1lez-Fern\u00e1ndez","year":"2020","journal-title":"Toxicol. Res."},{"key":"D5FO04442A\/cit36\/1","doi-asserted-by":"crossref","first-page":"4611","DOI":"10.1038\/onc.2015.523","volume":"35","author":"Fluckiger","year":"2016","journal-title":"Oncogene"},{"key":"D5FO04442A\/cit37\/1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s12263-018-0596-4","volume":"13","author":"Sam","year":"2018","journal-title":"Genes Nutr."},{"key":"D5FO04442A\/cit38\/1","doi-asserted-by":"crossref","first-page":"3236","DOI":"10.3390\/ijms25063236","volume":"25","author":"Magad\u00e1n-Corpas","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"D5FO04442A\/cit39\/1","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.3390\/nu16081161","volume":"16","author":"P\u00e9rez-Valero","year":"2024","journal-title":"Nutrients"},{"key":"D5FO04442A\/cit40\/1","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1080\/01635581.2017.1295088","volume":"69","author":"Hao","year":"2017","journal-title":"Nutr. Cancer"},{"key":"D5FO04442A\/cit41\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1207\/S15327914NC431_1","volume":"43","author":"Corpet","year":"2002","journal-title":"Nutr. Cancer"},{"key":"D5FO04442A\/cit42\/1","doi-asserted-by":"crossref","first-page":"115100","DOI":"10.1016\/j.taap.2020.115100","volume":"401","author":"Zhang","year":"2020","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"D5FO04442A\/cit43\/1","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1002\/mc.22353","volume":"55","author":"Kim","year":"2016","journal-title":"Mol. Carcinog."},{"key":"D5FO04442A\/cit44\/1","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.1002\/mnfr.201400293","volume":"58","author":"Kim","year":"2014","journal-title":"Mol. Nutr. Food Res."},{"key":"D5FO04442A\/cit45\/1","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.3389\/fimmu.2020.01407","volume":"11","author":"Ding","year":"2020","journal-title":"Front. Immunol."},{"key":"D5FO04442A\/cit46\/1","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1021\/acs.jafc.8b06665","volume":"67","author":"La","year":"2019","journal-title":"J. Agric. Food Chem."},{"key":"D5FO04442A\/cit47\/1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1093\/gastro\/goaa072","volume":"9","author":"Luo","year":"2021","journal-title":"Gastroenterol. Rep."},{"key":"D5FO04442A\/cit48\/1","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.bbrc.2005.06.182","volume":"334","author":"Shimizu","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"D5FO04442A\/cit49\/1","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s40538-023-00452-1","volume":"10","author":"Falc\u00f3n-Pi\u00f1eiro","year":"2023","journal-title":"Chem. Biol. Technol. Agric."},{"key":"D5FO04442A\/cit50\/1","doi-asserted-by":"crossref","first-page":"802","DOI":"10.3390\/nu16060802","volume":"16","author":"McAlpine","year":"2024","journal-title":"Nutrients"},{"key":"D5FO04442A\/cit51\/1","doi-asserted-by":"crossref","first-page":"111612","DOI":"10.1016\/j.fct.2020.111612","volume":"144","author":"Lira","year":"2020","journal-title":"Food Chem. Toxicol."},{"key":"D5FO04442A\/cit52\/1","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.3390\/antiox11102033","volume":"11","author":"Zhu","year":"2022","journal-title":"Antioxidants"},{"key":"D5FO04442A\/cit53\/1","doi-asserted-by":"crossref","first-page":"e2101004","DOI":"10.1002\/mnfr.202101004","volume":"66","author":"Zhu","year":"2022","journal-title":"Mol. Nutr. Food Res."},{"key":"D5FO04442A\/cit54\/1","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.3390\/nu13082595","volume":"13","author":"Vezza","year":"2021","journal-title":"Nutrients"},{"key":"D5FO04442A\/cit55\/1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201800653","volume":"63","author":"Vezza","year":"2019","journal-title":"Mol. Nutr. Food Res."},{"key":"D5FO04442A\/cit56\/1","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.3390\/nu15061363","volume":"15","author":"Guillam\u00f3n","year":"2023","journal-title":"Nutrients"},{"key":"D5FO04442A\/cit57\/1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s12602-017-9264-z","volume":"9","author":"Seddik","year":"2017","journal-title":"Probiotics Antimicrob. Proteins"},{"key":"D5FO04442A\/cit58\/1","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s12602-022-10020-y","volume":"16","author":"Fareez","year":"2024","journal-title":"Probiotics Antimicrob. Proteins"},{"key":"D5FO04442A\/cit59\/1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s12602-020-09699-8","volume":"13","author":"Sun","year":"2021","journal-title":"Probiotics Antimicrob. Proteins"},{"key":"D5FO04442A\/cit60\/1","doi-asserted-by":"crossref","first-page":"127624","DOI":"10.1016\/j.ijbiomac.2023.127624","volume":"254","author":"Wang","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D5FO04442A\/cit61\/1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0304-3835(92)90071-3","volume":"64","author":"Huang","year":"1992","journal-title":"Cancer Lett."},{"key":"D5FO04442A\/cit62\/1","first-page":"197","volume":"11","author":"Albanes","year":"2000","journal-title":"Cancer Causes Control"},{"key":"D5FO04442A\/cit63\/1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.freeradbiomed.2007.03.013","volume":"43","author":"Azzi","year":"2007","journal-title":"Free Radicals Biol. Med."},{"key":"D5FO04442A\/cit64\/1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.procbio.2024.04.015","volume":"142","author":"Imran","year":"2024","journal-title":"Process Biochem."},{"key":"D5FO04442A\/cit65\/1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1349-7006.2002.tb01251.x","volume":"93","author":"Kohno","year":"2002","journal-title":"Jpn. J. Cancer Res."},{"key":"D5FO04442A\/cit66\/1","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S0361-090X(02)00003-X","volume":"26","author":"Stone","year":"2002","journal-title":"Cancer Detect. Prev."},{"key":"D5FO04442A\/cit67\/1","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1007\/s10482-020-01445-y","volume":"113","author":"Khanna","year":"2020","journal-title":"Antonie Van Leeuwenhoek"},{"key":"D5FO04442A\/cit68\/1","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.3389\/fmicb.2018.02004","volume":"9","author":"Fern\u00e1ndez","year":"2018","journal-title":"Front. Microbiol."},{"key":"D5FO04442A\/cit69\/1","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1016\/j.ijbiomac.2020.11.089","volume":"167","author":"Ferreira-Lazarte","year":"2021","journal-title":"Int. J. Biol. Macromol."},{"key":"D5FO04442A\/cit70\/1","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/978-1-4939-3603-8_26","volume":"1422","author":"Parang","year":"2016","journal-title":"Methods Mol. Biol."},{"key":"D5FO04442A\/cit71\/1","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1093\/bioinformatics\/btr507","volume":"27","author":"Mago\u010d","year":"2011","journal-title":"Bioinformatics"},{"key":"D5FO04442A\/cit72\/1","doi-asserted-by":"crossref","first-page":"e107","DOI":"10.1002\/imt2.107","volume":"2","author":"Chen","year":"2023","journal-title":"iMeta"},{"key":"D5FO04442A\/cit73\/1","doi-asserted-by":"crossref","first-page":"e2584","DOI":"10.7717\/peerj.2584","volume":"4","author":"Rognes","year":"2016","journal-title":"PeerJ"},{"key":"D5FO04442A\/cit74\/1","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/nmeth.3869","volume":"13","author":"Callahan","year":"2016","journal-title":"Nat. Methods"},{"key":"D5FO04442A\/cit75\/1","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/s41587-019-0209-9","volume":"37","author":"Bolyen","year":"2019","journal-title":"Nat. Biotechnol."},{"key":"D5FO04442A\/cit76\/1","doi-asserted-by":"crossref","first-page":"e100","DOI":"10.1002\/cpbi.100","volume":"70","author":"Estaki","year":"2020","journal-title":"Curr. Protoc. Bioinf."},{"key":"D5FO04442A\/cit77\/1","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/s41587-023-01845-1","volume":"42","author":"McDonald","year":"2024","journal-title":"Nat. Biotechnol."},{"key":"D5FO04442A\/cit78\/1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1109\/18.61115","volume":"37","author":"Lin","year":"1991","journal-title":"IEEE Trans. Inf. Theory"},{"key":"D5FO04442A\/cit79\/1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.ecocom.2017.07.003","volume":"31","author":"Ricotta","year":"2017","journal-title":"Ecol. Complex."},{"key":"D5FO04442A\/cit80\/1","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1137\/100804139","volume":"33","author":"Halko","year":"2011","journal-title":"SIAM J. Sci. Comput."},{"key":"D5FO04442A\/cit81\/1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/2047-217X-2-16","volume":"2","author":"V\u00e1zquez-Baeza","year":"2013","journal-title":"Gigascience"},{"key":"D5FO04442A\/cit82\/1","first-page":"32","volume":"26","author":"Anderson","year":"2001","journal-title":"Austral. Ecol."},{"key":"D5FO04442A\/cit83\/1","doi-asserted-by":"crossref","first-page":"e1009442","DOI":"10.1371\/journal.pcbi.1009442","volume":"17","author":"Mallick","year":"2021","journal-title":"PLoS Comput. Biol."},{"key":"D5FO04442A\/cit84\/1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s12944-020-01205-x","volume":"19","author":"Fern\u00e1ndez","year":"2020","journal-title":"Lipids Health Dis."},{"key":"D5FO04442A\/cit85\/1","doi-asserted-by":"crossref","first-page":"3236","DOI":"10.3390\/ijms25063236","volume":"25","author":"Magad\u00e1n-Corpas","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"D5FO04442A\/cit86\/1","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1080\/10715760500197177","volume":"39","author":"Mazzon","year":"2005","journal-title":"Free Radical Res."},{"key":"D5FO04442A\/cit87\/1","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.crohns.2011.08.012","volume":"6","author":"Br\u00fcckner","year":"2012","journal-title":"J. Crohns Colitis"},{"key":"D5FO04442A\/cit88\/1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.ctim.2019.01.015","volume":"43","author":"Barbalho","year":"2019","journal-title":"Complement. Ther. Med."},{"key":"D5FO04442A\/cit89\/1","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/j.fshw.2022.10.003","volume":"12","author":"Du","year":"2023","journal-title":"Food Sci. Hum. Wellness"},{"key":"D5FO04442A\/cit90\/1","doi-asserted-by":"crossref","first-page":"773","DOI":"10.3390\/nu13030773","volume":"13","author":"Veenstra","year":"2021","journal-title":"Nutrients"},{"key":"D5FO04442A\/cit91\/1","doi-asserted-by":"crossref","first-page":"11036","DOI":"10.1038\/s41598-017-11408-5","volume":"7","author":"Yang","year":"2017","journal-title":"Sci. Rep."},{"key":"D5FO04442A\/cit92\/1","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.14309\/01.ajg.0000995988.33419.a7","volume":"118","author":"Zinger","year":"2023","journal-title":"Am. J. Gastroenterol."},{"key":"D5FO04442A\/cit93\/1","doi-asserted-by":"crossref","first-page":"492","DOI":"10.5152\/tjg.2015.0106","volume":"26","author":"Ge","year":"2020","journal-title":"Turk. J.\nGastroenterol."},{"key":"D5FO04442A\/cit94\/1","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1136\/gut.2003.024828","volume":"53","author":"Jowett","year":"2004","journal-title":"Gut"},{"key":"D5FO04442A\/cit95\/1","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1093\/ecco-jcc\/jjac054","volume":"16","author":"Dong","year":"2022","journal-title":"J. Crohns Colitis"},{"key":"D5FO04442A\/cit96\/1","doi-asserted-by":"crossref","first-page":"646819","DOI":"10.3389\/fnut.2021.646819","volume":"8","author":"Li","year":"2021","journal-title":"Front. Nutr."},{"key":"D5FO04442A\/cit97\/1","doi-asserted-by":"crossref","first-page":"e1800653","DOI":"10.1002\/mnfr.201800653","volume":"63","author":"Vezza","year":"2019","journal-title":"Mol. Nutr. Food Res."},{"key":"D5FO04442A\/cit98\/1","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1159\/000320392","volume":"28","author":"Atreya","year":"2010","journal-title":"Dig. Dis."},{"key":"D5FO04442A\/cit99\/1","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.3390\/nu13082595","volume":"13","author":"Vezza","year":"2021","journal-title":"Nutrients"},{"key":"D5FO04442A\/cit100\/1","doi-asserted-by":"crossref","first-page":"2538","DOI":"10.3390\/cells12212538","volume":"12","author":"Magry\u015b","year":"2023","journal-title":"Cells"},{"key":"D5FO04442A\/cit101\/1","doi-asserted-by":"crossref","first-page":"11008","DOI":"10.1039\/D2FO00001F","volume":"13","author":"Zhang","year":"2022","journal-title":"Food Funct."},{"key":"D5FO04442A\/cit102\/1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/s41564-021-01010-x","volume":"7","author":"Buffa","year":"2021","journal-title":"Nat. Microbiol."},{"key":"D5FO04442A\/cit103\/1","doi-asserted-by":"crossref","first-page":"e2101498118","DOI":"10.1073\/pnas.2101498118","volume":"118","author":"Rajakovich","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D5FO04442A\/cit104\/1","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1172\/JCI94601","volume":"129","author":"Koeth","year":"2018","journal-title":"J. Clin. Invest."},{"key":"D5FO04442A\/cit105\/1","doi-asserted-by":"crossref","first-page":"10397","DOI":"10.3390\/ijms251910397","volume":"25","author":"Cuervo","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"D5FO04442A\/cit106\/1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.cmet.2012.12.011","volume":"17","author":"Bennett","year":"2013","journal-title":"Cell Metab."},{"key":"D5FO04442A\/cit107\/1","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/s40168-020-00912-y","volume":"8","author":"Wu","year":"2020","journal-title":"Microbiome"},{"key":"D5FO04442A\/cit108\/1","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1186\/1471-2164-16-S7-S4","volume":"16","author":"Xu","year":"2015","journal-title":"BMC Genomics"},{"key":"D5FO04442A\/cit109\/1","first-page":"1","volume":"2022","author":"Yang","year":"2022","journal-title":"J. Immunol. Res."},{"key":"D5FO04442A\/cit110\/1","doi-asserted-by":"crossref","first-page":"14783","DOI":"10.1038\/s41598-019-51437-w","volume":"9","author":"Fern\u00e1ndez","year":"2019","journal-title":"Sci. Rep."},{"key":"D5FO04442A\/cit111\/1","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.3389\/fmicb.2018.02004","volume":"9","author":"Fern\u00e1ndez","year":"2018","journal-title":"Front. Microbiol."},{"key":"D5FO04442A\/cit112\/1","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/S0271-5317(05)80780-8","volume":"12","author":"R\u00e9m\u00e9sy","year":"1992","journal-title":"Nutr. Res."},{"key":"D5FO04442A\/cit113\/1","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1093\/jn\/125.4.1010","volume":"125","author":"Younes","year":"1995","journal-title":"J. Nutr."},{"key":"D5FO04442A\/cit114\/1","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1136\/gutjnl-2023-330301","volume":"73","author":"Paone","year":"2024","journal-title":"Gut"},{"key":"D5FO04442A\/cit115\/1","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1093\/jn\/127.1.130","volume":"127","author":"Campbell","year":"1997","journal-title":"J. Nutr."},{"key":"D5FO04442A\/cit116\/1","doi-asserted-by":"crossref","first-page":"111553","DOI":"10.1016\/j.intimp.2024.111553","volume":"128","author":"Ren","year":"2024","journal-title":"Int. Immunopharmacol."},{"key":"D5FO04442A\/cit117\/1","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.3390\/nu10091298","volume":"10","author":"Liu","year":"2018","journal-title":"Nutrients"},{"key":"D5FO04442A\/cit118\/1","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1111\/1750-3841.15684","volume":"86","author":"Zhu","year":"2021","journal-title":"J. Food Sci."},{"key":"D5FO04442A\/cit119\/1","doi-asserted-by":"crossref","first-page":"13592","DOI":"10.1021\/acs.jafc.2c03464","volume":"70","author":"Dai","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"D5FO04442A\/cit120\/1","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.3390\/foods13111599","volume":"13","author":"Rocha","year":"2024","journal-title":"Foods"},{"key":"D5FO04442A\/cit121\/1","doi-asserted-by":"crossref","first-page":"757718","DOI":"10.3389\/fcimb.2021.757718","volume":"11","author":"Nie","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"D5FO04442A\/cit122\/1","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.chom.2014.02.005","volume":"15","author":"Gevers","year":"2014","journal-title":"Cell Host Microbe"},{"key":"D5FO04442A\/cit123\/1","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1158\/1078-0432.CCR-16-1599","volume":"23","author":"Liang","year":"2017","journal-title":"Clin. Cancer Res."},{"key":"D5FO04442A\/cit124\/1","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1038\/ismej.2011.109","volume":"6","author":"Wang","year":"2012","journal-title":"ISME J."},{"key":"D5FO04442A\/cit125\/1","doi-asserted-by":"crossref","first-page":"113846","DOI":"10.1016\/j.celrep.2024.113846","volume":"43","author":"Dong","year":"2024","journal-title":"Cell Rep."},{"key":"D5FO04442A\/cit126\/1","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1136\/gutjnl-2023-330291","volume":"72","author":"Kang","year":"2023","journal-title":"Gut"},{"key":"D5FO04442A\/cit127\/1","doi-asserted-by":"crossref","first-page":"790561","DOI":"10.3389\/fnut.2021.790561","volume":"8","author":"Cheng","year":"2021","journal-title":"Front. Nutr."},{"key":"D5FO04442A\/cit128\/1","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1186\/s12935-021-01971-3","volume":"21","author":"Faghfoori","year":"2021","journal-title":"Cancer Cell Int."},{"key":"D5FO04442A\/cit129\/1","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.3390\/antiox11112146","volume":"11","author":"Vitheejongjaroen","year":"2022","journal-title":"Antioxidants"},{"key":"D5FO04442A\/cit130\/1","doi-asserted-by":"crossref","first-page":"614","DOI":"10.3389\/fmicb.2018.00614","volume":"9","author":"Pasquereau-Kotula","year":"2018","journal-title":"Front. Microbiol."},{"key":"D5FO04442A\/cit131\/1","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1186\/s12934-014-0154-8","volume":"13","author":"Jim\u00e9nez","year":"2014","journal-title":"Microb. Cell Fact."},{"key":"D5FO04442A\/cit132\/1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1196\/annals.1331.022","volume":"1031","author":"Stone","year":"2004","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"D5FO04442A\/cit133\/1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/lite.201600013","volume":"28","author":"Ismail","year":"2016","journal-title":"Lipid Technol."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2026\/FO\/D5FO04442A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:53:55Z","timestamp":1782885235000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/fo\/article\/17\/5\/2457-2475\/893333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":133,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,3,9]]}},"URL":"https:\/\/doi.org\/10.1039\/d5fo04442a","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D5FO04442A\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5FO04442A\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5FO04442A\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5FO04442A\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5FO04442A\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5FO04442A\/v2\/review1","asserted-by":"object"}]},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}