{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T22:40:43Z","timestamp":1792449643805,"version":"4.5.0"},"reference-count":45,"publisher":"Royal Society of Chemistry (RSC)","issue":"11","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":118,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["40B2-0_211752"],"award-info":[{"award-number":["40B2-0_211752"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Lab Chip"],"abstract":"<jats:p>We introduce an acoustic micromanipulation platform that concentrates and aligns organoids within a histology-compatible hydrogel block. This versatile and scalable platform significantly increases the information content of histological sections.<\/jats:p>","DOI":"10.1039\/d5lc00153f","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T03:21:15Z","timestamp":1745896875000},"page":"2732-2743","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["An acoustic levitation platform for high-content histological analysis of 3D tissue culture"],"prefix":"10.1039","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5700-2862","authenticated-orcid":false,"given":"Emilie","family":"Vuille-dit-Bille","sequence":"first","affiliation":[{"name":"CSEM SA, Neuch\u00e2tel, Switzerland"},{"name":"Institute of Mechanical Engineering, EPFL, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line Loussert","family":"Fonta","sequence":"additional","affiliation":[{"name":"CSEM SA, Neuch\u00e2tel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2016-9543","authenticated-orcid":false,"given":"Sarah","family":"Heub","sequence":"additional","affiliation":[{"name":"CSEM SA, Neuch\u00e2tel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0934-2026","authenticated-orcid":false,"given":"St\u00e9phanie","family":"Boder-Pasche","sequence":"additional","affiliation":[{"name":"CSEM SA, Neuch\u00e2tel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7226-3382","authenticated-orcid":false,"given":"Mahmut Selman","family":"Sakar","sequence":"additional","affiliation":[{"name":"Institute of Mechanical Engineering, EPFL, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0321-8756","authenticated-orcid":false,"given":"Gilles","family":"Weder","sequence":"additional","affiliation":[{"name":"CSEM SA, Neuch\u00e2tel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D5LC00153F\/cit1\/1","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/s41578-021-00279-y","volume":"6","author":"Hofer","year":"2021","journal-title":"Nat. Rev. Mater."},{"key":"D5LC00153F\/cit2\/1","doi-asserted-by":"crossref","first-page":"101582","DOI":"10.1016\/j.apmt.2022.101582","volume":"29","author":"Unagolla","year":"2022","journal-title":"Appl. Mater. Today"},{"key":"D5LC00153F\/cit3\/1","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1038\/s41596-019-0160-8","volume":"14","author":"Dekkers","year":"2019","journal-title":"Nat. Protoc."},{"key":"D5LC00153F\/cit4\/1","doi-asserted-by":"crossref","first-page":"391","DOI":"10.3390\/cells8050391","volume":"8","author":"Cora","year":"2019","journal-title":"Cells"},{"key":"D5LC00153F\/cit5\/1","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.1038\/s41596-021-00502-8","volume":"16","author":"Weiss","year":"2021","journal-title":"Nat. Protoc."},{"key":"D5LC00153F\/cit7\/1","doi-asserted-by":"crossref","first-page":"679226","DOI":"10.3389\/fcell.2021.679226","volume":"9","author":"Susaki","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"D5LC00153F\/cit8\/1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1111\/joa.13309","volume":"238","author":"Tian","year":"2021","journal-title":"J. Anat."},{"key":"D5LC00153F\/cit9\/1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.media.2018.02.004","volume":"46","author":"Pichat","year":"2018","journal-title":"Med. Image Anal."},{"key":"D5LC00153F\/cit10\/1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/978-1-0716-1948-3_3","volume-title":"Immunohistochemistry and Immunocytochemistry: Methods and Protocols","author":"Sampedro-Carrillo","year":"2022","unstructured":"E. A.Sampedro-Carrillo , in  Immunohistochemistry and Immunocytochemistry: Methods and Protocols , ed.  L. Del Valle ,  Springer US ,  New York, NY ,  2022 ,  pp. 33\u201345"},{"key":"D5LC00153F\/cit11\/1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.scr.2018.02.003","volume":"28","author":"Ferguson","year":"2018","journal-title":"Stem Cell Res."},{"key":"D5LC00153F\/cit12\/1","doi-asserted-by":"crossref","first-page":"9991","DOI":"10.1038\/s41598-022-13987-4","volume":"12","author":"Heub","year":"2022","journal-title":"Sci. Rep."},{"key":"D5LC00153F\/cit13\/1","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/s41598-024-83164-2","volume":"15","author":"Vuille-dit-Bille","year":"2025","journal-title":"Sci. Rep."},{"key":"D5LC00153F\/cit14\/1","doi-asserted-by":"crossref","first-page":"151095","DOI":"10.1016\/j.ejcb.2020.151095","volume":"99","author":"Moraes","year":"2020","journal-title":"Eur. J. Cell Biol."},{"key":"D5LC00153F\/cit15\/1","doi-asserted-by":"crossref","first-page":"16287","DOI":"10.1038\/s41598-019-52007-w","volume":"9","author":"Gabriel","year":"2019","journal-title":"Sci. Rep."},{"key":"D5LC00153F\/cit16\/1","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1038\/s41551-020-0565-2","volume":"4","author":"Brandenberg","year":"2020","journal-title":"Nat. Biomed. Eng."},{"key":"D5LC00153F\/cit17\/1","doi-asserted-by":"crossref","first-page":"032002","DOI":"10.1088\/1758-5090\/abe6f2","volume":"13","author":"Decarli","year":"2021","journal-title":"Biofabrication"},{"key":"D5LC00153F\/cit18\/1","doi-asserted-by":"crossref","first-page":"137173","DOI":"10.1016\/j.snb.2024.137173","volume":"427","author":"Hammarstr\u00f6m","year":"2025","journal-title":"Sens. Actuators, B"},{"key":"D5LC00153F\/cit19\/1","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1039\/C6LC00444J","volume":"16","author":"Chen","year":"2016","journal-title":"Lab Chip"},{"key":"D5LC00153F\/cit20\/1","doi-asserted-by":"crossref","first-page":"733","DOI":"10.18063\/ijb.733","volume":"9","author":"Miao","year":"2023","journal-title":"Int. J. Bioprint."},{"key":"D5LC00153F\/cit21\/1","doi-asserted-by":"crossref","first-page":"2466","DOI":"10.1039\/C8LC00537K","volume":"18","author":"Olofsson","year":"2018","journal-title":"Lab Chip"},{"key":"D5LC00153F\/cit22\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41378-023-00609-w","volume":"10","author":"Wu","year":"2024","journal-title":"Microsyst. Nanoeng."},{"key":"D5LC00153F\/cit23\/1","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1038\/s44222-024-00166-5","volume":"2","author":"Melde","year":"2024","journal-title":"Nat. Rev. Bioeng."},{"key":"D5LC00153F\/cit24\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s43586-022-00109-7","volume":"2","author":"Rufo","year":"2022","journal-title":"Nat. Rev. Methods Primers"},{"key":"D5LC00153F\/cit25\/1","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1039\/D0LC01141J","volume":"21","author":"Ao","year":"2021","journal-title":"Lab Chip"},{"key":"D5LC00153F\/cit26\/1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/adma.201503916","volume":"28","author":"Bouyer","year":"2016","journal-title":"Adv. Mater."},{"key":"D5LC00153F\/cit27\/1","doi-asserted-by":"crossref","first-page":"8355","DOI":"10.1038\/s41598-021-87459-6","volume":"11","author":"Jeger-Madiot","year":"2021","journal-title":"Sci. Rep."},{"key":"D5LC00153F\/cit28\/1","doi-asserted-by":"crossref","first-page":"100110","DOI":"10.1016\/j.mtbio.2021.100110","volume":"10","author":"Guex","year":"2021","journal-title":"Mater. Today Bio"},{"key":"D5LC00153F\/cit29\/1","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/s13538-017-0552-6","volume":"48","author":"Andrade","year":"2018","journal-title":"Braz. J. Phys."},{"key":"D5LC00153F\/cit30\/1","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1039\/c2lc21068a","volume":"12","author":"Bruus","year":"2012","journal-title":"Lab Chip"},{"key":"D5LC00153F\/cit31\/1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.optlaseng.2016.10.023","volume":"99","author":"Rothberg","year":"2017","journal-title":"Opt. Lasers Eng."},{"key":"D5LC00153F\/cit32\/1","doi-asserted-by":"crossref","first-page":"113500","DOI":"10.1016\/j.sna.2022.113500","volume":"341","author":"Cheng","year":"2022","journal-title":"Sens. Actuators, A"},{"key":"D5LC00153F\/cit33\/1","doi-asserted-by":"crossref","first-page":"4947","DOI":"10.1039\/C7PY00559H","volume":"8","author":"Lazzari","year":"2017","journal-title":"Polym. Chem."},{"key":"D5LC00153F\/cit34\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neo.2014.12.004","volume":"17","author":"Weiswald","year":"2015","journal-title":"Neoplasia"},{"key":"D5LC00153F\/cit35\/1","doi-asserted-by":"crossref","first-page":"2215043","DOI":"10.1002\/adfm.202215043","volume":"33","author":"Fang","year":"2023","journal-title":"Adv. Funct. Mater."},{"key":"D5LC00153F\/cit36\/1","doi-asserted-by":"crossref","first-page":"874","DOI":"10.3390\/cancers13040874","volume":"13","author":"Gunti","year":"2021","journal-title":"Cancers"},{"key":"D5LC00153F\/cit37\/1","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1016\/j.yexcr.2012.03.026","volume":"318","author":"Karlsson","year":"2012","journal-title":"Exp. Cell Res."},{"key":"D5LC00153F\/cit38\/1","doi-asserted-by":"crossref","first-page":"e0291942","DOI":"10.1371\/journal.pone.0291942","volume":"18","author":"Yalcin","year":"2023","journal-title":"PLoS One"},{"key":"D5LC00153F\/cit39\/1","doi-asserted-by":"crossref","first-page":"6262","DOI":"10.3390\/molecules26206262","volume":"26","author":"Kulesza","year":"2021","journal-title":"Molecules"},{"key":"D5LC00153F\/cit40\/1","doi-asserted-by":"crossref","first-page":"115279","DOI":"10.1016\/j.taap.2020.115279","volume":"408","author":"Basharat","year":"2020","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"D5LC00153F\/cit41\/1","doi-asserted-by":"crossref","first-page":"4863","DOI":"10.1038\/s41598-019-41273-3","volume":"9","author":"Eilenberger","year":"2019","journal-title":"Sci. Rep."},{"key":"D5LC00153F\/cit42\/1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.toxlet.2021.04.004","volume":"345","author":"Coltman","year":"2021","journal-title":"Toxicol. Lett."},{"key":"D5LC00153F\/cit43\/1","first-page":"1083","volume":"88","author":"Ramaiahgari","year":"2014","journal-title":"Arch. Toxicol."},{"key":"D5LC00153F\/cit44\/1","doi-asserted-by":"publisher","DOI":"10.1101\/2025.02.09.637288.v1","volume-title":"bioRxiv","author":"Deshmukh","year":"2025","unstructured":"D. V.Deshmukh ,  E.Vuille-dit-Bille ,  S.Joshi ,  N.Gerber ,  C.Fux ,  A.Eichenberger ,  E.Bono ,  M.Rimann ,  S.Heub ,  D.Migliozzi ,  S.Boder-Pasche ,  G.Weder ,  J.Dual  and  M. W.Tibbitt ,  bioRxiv ,  2025 , preprint,  10.1101\/2025.02.09.637288.v1"},{"key":"D5LC00153F\/cit45\/1","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1038\/s41467-024-46506-2","volume":"15","author":"Kv\u00e5le L\u00f8vmo","year":"2024","journal-title":"Nat. Commun."},{"key":"D5LC00153F\/cit46\/1","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"}],"container-title":["Lab on a Chip"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/LC\/D5LC00153F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:20:00Z","timestamp":1782969600000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/lc\/article\/25\/11\/2732-2743\/895229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":45,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,5,28]]}},"URL":"https:\/\/doi.org\/10.1039\/d5lc00153f","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D5LC00153F\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5LC00153F\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5LC00153F\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5LC00153F\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5LC00153F\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5LC00153F\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5LC00153F\/v2\/decision1","asserted-by":"object"}]},"ISSN":["1473-0197","1473-0189"],"issn-type":[{"value":"1473-0197","type":"print"},{"value":"1473-0189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}