{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T06:44:14Z","timestamp":1782974654658,"version":"3.54.5"},"reference-count":49,"publisher":"Royal Society of Chemistry (RSC)","issue":"42","license":[{"start":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:00:00Z","timestamp":1792195200000},"content-version":"am","delay-in-days":654,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82273898"],"award-info":[{"award-number":["82273898"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Nanoscale"],"abstract":"<jats:p>\n                    Schematic of a multifunctional nanosystem for the modulation of overexpressed GSH in the TME to enhance therapeutic efficacy and detection of\n                    <jats:sup>1<\/jats:sup>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    to achieve precise PDT.\n                  <\/jats:p>","DOI":"10.1039\/d5nr01806d","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T14:38:09Z","timestamp":1760711889000},"page":"24742-24754","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multifunctional nano-MOFs based on tumor microenvironment modulation for detecting singlet oxygen and enhancing photodynamic therapy"],"prefix":"10.1039","volume":"17","author":[{"given":"Yongdan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linshan","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shumeng","family":"Li","sequence":"additional","affiliation":[{"name":"School of Pharmacy, North Sichuan Medical College, Nanchong 637100, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Qiqihar Medical University, Qiqihar 161006, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4210-9381","authenticated-orcid":false,"given":"Xiaohong","family":"Hou","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"issue":"29","key":"D5NR01806D\/cit1\/1","doi-asserted-by":"publisher","first-page":"9846","DOI":"10.1002\/anie.201903981","volume":"58","author":"Wang","year":"2019","journal-title":"Angew. Chem., Int. Ed."},{"key":"D5NR01806D\/cit2\/1","doi-asserted-by":"publisher","first-page":"117282","DOI":"10.1016\/j.jlumin.2020.117282","volume":"224","author":"Zang","year":"2020","journal-title":"J. Lumin."},{"issue":"43","key":"D5NR01806D\/cit3\/1","doi-asserted-by":"publisher","first-page":"39594","DOI":"10.1021\/acsami.9b14084","volume":"11","author":"Zhang","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"21","key":"D5NR01806D\/cit4\/1","doi-asserted-by":"publisher","first-page":"6433","DOI":"10.1039\/c7cs00525c","volume":"46","author":"Rajora","year":"2017","journal-title":"Chem. Soc. Rev."},{"key":"D5NR01806D\/cit5\/1","doi-asserted-by":"publisher","first-page":"138621","DOI":"10.1016\/j.cej.2022.138621","volume":"451","author":"Li","year":"2023","journal-title":"Chem. Eng. J."},{"issue":"5","key":"D5NR01806D\/cit6\/1","doi-asserted-by":"publisher","first-page":"1560","DOI":"10.1002\/wnan.1560","volume":"11","author":"Shi","year":"2019","journal-title":"Wiley Interdiscip. Rev.:Nanomed. Nanobiotechnol."},{"key":"D5NR01806D\/cit7\/1","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.biomaterials.2018.06.007","volume":"178","author":"Gao","year":"2018","journal-title":"Biomaterials"},{"issue":"48","key":"D5NR01806D\/cit8\/1","doi-asserted-by":"publisher","first-page":"57009","DOI":"10.1021\/acsami.1c18601","volume":"13","author":"Wang","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"68","key":"D5NR01806D\/cit9\/1","doi-asserted-by":"publisher","first-page":"41560","DOI":"10.1039\/d0ra08617g","volume":"10","author":"Simelane","year":"2020","journal-title":"RSC Adv."},{"key":"D5NR01806D\/cit10\/1","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1016\/j.ijbiomac.2022.03.139","volume":"207","author":"Liu","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"D5NR01806D\/cit11\/1","doi-asserted-by":"publisher","first-page":"135813","DOI":"10.1016\/j.snb.2024.135813","volume":"412","author":"Zhao","year":"2024","journal-title":"Sens. Actuators, B"},{"issue":"9","key":"D5NR01806D\/cit12\/1","doi-asserted-by":"publisher","first-page":"3349","DOI":"10.1021\/acssensors.3c00294","volume":"8","author":"Zhou","year":"2023","journal-title":"ACS Sens."},{"issue":"15","key":"D5NR01806D\/cit13\/1","doi-asserted-by":"publisher","first-page":"1808200","DOI":"10.1002\/adma.201808200","volume":"31","author":"Min","year":"2019","journal-title":"Adv. Mater."},{"key":"D5NR01806D\/cit14\/1","doi-asserted-by":"publisher","first-page":"2305708","DOI":"10.1002\/smll.202305708","author":"Yu","year":"2023","journal-title":"Small"},{"issue":"13","key":"D5NR01806D\/cit15\/1","doi-asserted-by":"publisher","first-page":"4003","DOI":"10.3390\/molecules27134003","volume":"27","author":"Qi","year":"2022","journal-title":"Molecules"},{"key":"D5NR01806D\/cit16\/1","doi-asserted-by":"publisher","first-page":"111702","DOI":"10.1016\/j.matdes.2023.111702","volume":"227","author":"Chen","year":"2023","journal-title":"Mater. Des."},{"issue":"6","key":"D5NR01806D\/cit17\/1","doi-asserted-by":"publisher","first-page":"2764","DOI":"10.1007\/s10853-023-08156-5","volume":"58","author":"Zhang","year":"2023","journal-title":"J. Mater. Sci."},{"issue":"18","key":"D5NR01806D\/cit18\/1","doi-asserted-by":"publisher","first-page":"5477","DOI":"10.1002\/anie.201510748","volume":"55","author":"Fan","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"issue":"10","key":"D5NR01806D\/cit19\/1","doi-asserted-by":"publisher","first-page":"13500","DOI":"10.1021\/acsnano.0c05499","volume":"14","author":"Wang","year":"2020","journal-title":"ACS Nano"},{"issue":"35","key":"D5NR01806D\/cit20\/1","doi-asserted-by":"publisher","first-page":"17982","DOI":"10.1039\/d0nr04067c","volume":"12","author":"Zhang","year":"2020","journal-title":"Nanoscale"},{"issue":"18","key":"D5NR01806D\/cit21\/1","doi-asserted-by":"publisher","first-page":"4891","DOI":"10.1002\/anie.201710800","volume":"57","author":"Zhang","year":"2018","journal-title":"Angew. Chem., Int. Ed."},{"issue":"38","key":"D5NR01806D\/cit22\/1","doi-asserted-by":"publisher","first-page":"11467","DOI":"10.1002\/anie.201605509","volume":"55","author":"Ju","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"issue":"27","key":"D5NR01806D\/cit23\/1","doi-asserted-by":"publisher","first-page":"e2310300","DOI":"10.1002\/smll.202310300","volume":"20","author":"Wang","year":"2024","journal-title":"Small"},{"issue":"11","key":"D5NR01806D\/cit24\/1","doi-asserted-by":"publisher","first-page":"8141","DOI":"10.1021\/acs.nanolett.0c03127","volume":"20","author":"Chen","year":"2020","journal-title":"Nano Lett."},{"issue":"5","key":"D5NR01806D\/cit25\/1","doi-asserted-by":"publisher","first-page":"4886","DOI":"10.1021\/acsnano.8b01893","volume":"12","author":"Liu","year":"2018","journal-title":"ACS Nano"},{"issue":"30","key":"D5NR01806D\/cit26\/1","doi-asserted-by":"publisher","first-page":"5490","DOI":"10.1002\/adfm.201600676","volume":"26","author":"Zhu","year":"2016","journal-title":"Adv. Funct. Mater."},{"issue":"3","key":"D5NR01806D\/cit27\/1","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1039\/d2tb01659a","volume":"11","author":"Zhang","year":"2023","journal-title":"J. Mater. Chem. B"},{"issue":"30","key":"D5NR01806D\/cit28\/1","doi-asserted-by":"publisher","first-page":"35444","DOI":"10.1021\/acsami.1c08927","volume":"13","author":"Ming","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"28","key":"D5NR01806D\/cit29\/1","doi-asserted-by":"publisher","first-page":"2000589","DOI":"10.1002\/smll.202000589","volume":"16","author":"Wang","year":"2020","journal-title":"Small"},{"key":"D5NR01806D\/cit30\/1","doi-asserted-by":"publisher","first-page":"2309086","DOI":"10.1002\/smll.202309086","author":"Cai","year":"2024","journal-title":"Small"},{"key":"D5NR01806D\/cit31\/1","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.jphotobiol.2015.02.014","volume":"145","author":"Lagunes","year":"2015","journal-title":"J. Photochem. Photobiol., B"},{"issue":"39","key":"D5NR01806D\/cit32\/1","doi-asserted-by":"publisher","first-page":"11793","DOI":"10.1002\/anie.201705803","volume":"56","author":"Hananya","year":"2017","journal-title":"Angew. Chem., Int. Ed."},{"issue":"7","key":"D5NR01806D\/cit33\/1","doi-asserted-by":"publisher","first-page":"e0200006","DOI":"10.1371\/journal.pone.0200006","volume":"13","author":"Zanocco","year":"2018","journal-title":"PLoS One"},{"key":"D5NR01806D\/cit34\/1","doi-asserted-by":"publisher","first-page":"133584","DOI":"10.1016\/j.foodchem.2022.133584","volume":"395","author":"Zheng","year":"2022","journal-title":"Food Chem."},{"issue":"10","key":"D5NR01806D\/cit35\/1","doi-asserted-by":"publisher","first-page":"4603","DOI":"10.3390\/s23104603","volume":"23","author":"Zanocco","year":"2023","journal-title":"Sensors"},{"issue":"1","key":"D5NR01806D\/cit36\/1","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1021\/acs.jpcc.2c06821","volume":"127","author":"Cordoba","year":"2023","journal-title":"J. Phys. Chem. C"},{"issue":"6","key":"D5NR01806D\/cit37\/1","doi-asserted-by":"publisher","first-page":"3559","DOI":"10.1021\/acs.est.0c07922","volume":"55","author":"Durantini","year":"2021","journal-title":"Environ. Sci. Technol."},{"issue":"12","key":"D5NR01806D\/cit38\/1","doi-asserted-by":"publisher","first-page":"3933","DOI":"10.1039\/d1an00456e","volume":"146","author":"Nath","year":"2021","journal-title":"Analyst"},{"issue":"16","key":"D5NR01806D\/cit39\/1","doi-asserted-by":"publisher","first-page":"2000533","DOI":"10.1002\/adhm.202000533","volume":"9","author":"Deng","year":"2020","journal-title":"Adv. Healthcare Mater."},{"key":"D5NR01806D\/cit40\/1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/s1872-2067(22)64193-7","volume":"45","author":"Jiao","year":"2023","journal-title":"Chin. J. Catal."},{"key":"D5NR01806D\/cit41\/1","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.ccr.2017.09.007","volume":"379","author":"Lan","year":"2019","journal-title":"Coord. Chem. Rev."},{"key":"D5NR01806D\/cit42\/1","doi-asserted-by":"publisher","first-page":"124493","DOI":"10.1016\/j.talanta.2023.124493","volume":"259","author":"Yang","year":"2023","journal-title":"Talanta"},{"issue":"12","key":"D5NR01806D\/cit43\/1","doi-asserted-by":"publisher","first-page":"5734","DOI":"10.1039\/d3mh01244a","volume":"10","author":"Li","year":"2023","journal-title":"Mater. Horiz."},{"key":"D5NR01806D\/cit44\/1","doi-asserted-by":"publisher","first-page":"137333","DOI":"10.1016\/j.cej.2022.137333","volume":"446","author":"Zhu","year":"2022","journal-title":"Chem. Eng. J."},{"issue":"2","key":"D5NR01806D\/cit45\/1","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1021\/acsanm.0c02916","volume":"4","author":"Yan","year":"2021","journal-title":"ACS Appl. Nano Mater."},{"issue":"43","key":"D5NR01806D\/cit46\/1","doi-asserted-by":"publisher","first-page":"58370","DOI":"10.1021\/acsami.4c13792","volume":"16","author":"Chen","year":"2024","journal-title":"ACS Appl. Nano Mater."},{"issue":"1","key":"D5NR01806D\/cit47\/1","doi-asserted-by":"publisher","first-page":"5227","DOI":"10.1038\/s41467-023-40897-4","volume":"14","author":"Li","year":"2023","journal-title":"Nat. Commun."},{"issue":"21","key":"D5NR01806D\/cit48\/1","doi-asserted-by":"publisher","first-page":"2103733","DOI":"10.1002\/adma.202100595","volume":"33","author":"Li","year":"2021","journal-title":"Adv. Mater."},{"issue":"13","key":"D5NR01806D\/cit49\/1","doi-asserted-by":"publisher","first-page":"6384","DOI":"10.1039\/c9nr01306g","volume":"11","author":"Hu","year":"2019","journal-title":"Nanoscale"}],"container-title":["Nanoscale"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/NR\/D5NR01806D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:15:43Z","timestamp":1782969343000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/nr\/article\/17\/42\/24742-24754\/901273"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":49,"journal-issue":{"issue":"42","published-print":{"date-parts":[[2025,10,30]]}},"URL":"https:\/\/doi.org\/10.1039\/d5nr01806d","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D5NR01806D\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5NR01806D\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5NR01806D\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5NR01806D\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5NR01806D\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5NR01806D\/v1\/decision1","asserted-by":"object"}]},"ISSN":["2040-3364","2040-3372"],"issn-type":[{"value":"2040-3364","type":"print"},{"value":"2040-3372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}