{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T01:30:15Z","timestamp":1791855015439,"version":"4.3.4"},"reference-count":57,"publisher":"Royal Society of Chemistry (RSC)","issue":"42","license":[{"start":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000},"content-version":"vor","delay-in-days":267,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<jats:p>Rational design of carbon dots through heteroatom doping and functional precursor selection for multifunctional enzyme-mimicking nanotherapeutics in oxidative stress-related diseases.<\/jats:p>","DOI":"10.1039\/d5ra05474e","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T08:43:04Z","timestamp":1758789784000},"page":"35421-35435","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Strategic engineering of carbon dots: multi-enzyme mimetics for advanced biomedical intervention in oxidative stress-related diseases"],"prefix":"10.1039","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8865-3273","authenticated-orcid":false,"given":"Qian","family":"He","sequence":"first","affiliation":[{"name":"Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"issue":"1","key":"D5RA05474E\/cit1\/1","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/s41467-025-55944-5","volume":"16","author":"Zheng","year":"2025","journal-title":"Nat. Commun."},{"issue":"16","key":"D5RA05474E\/cit2\/1","doi-asserted-by":"crossref","first-page":"15962","DOI":"10.1021\/acsnano.3c04134","volume":"17","author":"Shang","year":"2023","journal-title":"ACS Nano"},{"issue":"4","key":"D5RA05474E\/cit3\/1","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1039\/C8CS00457A","volume":"48","author":"Wu","year":"2019","journal-title":"Chem. Soc. Rev."},{"issue":"40","key":"D5RA05474E\/cit4\/1","doi-asserted-by":"crossref","first-page":"12736","DOI":"10.1021\/ja040082h","volume":"126","author":"Xu","year":"2004","journal-title":"J. Am. Chem. Soc."},{"issue":"16","key":"D5RA05474E\/cit5\/1","doi-asserted-by":"crossref","first-page":"e2418118","DOI":"10.1002\/adma.202418118","volume":"37","author":"Zhang","year":"2025","journal-title":"Adv. Mater."},{"issue":"2","key":"D5RA05474E\/cit6\/1","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/s41565-021-01051-7","volume":"17","author":"\u0110or\u0111evi\u0107","year":"2022","journal-title":"Nat. Nanotechnol."},{"issue":"5","key":"D5RA05474E\/cit7\/1","doi-asserted-by":"crossref","first-page":"110618","DOI":"10.1016\/j.cclet.2024.110618","volume":"36","author":"Liu","year":"2025","journal-title":"Chin. Chem. Lett."},{"issue":"34","key":"D5RA05474E\/cit8\/1","doi-asserted-by":"crossref","first-page":"14426","DOI":"10.1039\/D1NR03999G","volume":"13","author":"Kim","year":"2021","journal-title":"Nanoscale"},{"key":"D5RA05474E\/cit9\/1","doi-asserted-by":"crossref","first-page":"132331","DOI":"10.1016\/j.jhazmat.2023.132331","volume":"459","author":"Hua","year":"2023","journal-title":"J. Hazard. Mater."},{"issue":"42","key":"D5RA05474E\/cit10\/1","first-page":"8","volume":"63","author":"Zhang","year":"2024","journal-title":"Inorg. Chem."},{"issue":"24","key":"D5RA05474E\/cit11\/1","doi-asserted-by":"crossref","first-page":"7756","DOI":"10.1021\/ja062677d","volume":"128","author":"Sun","year":"2006","journal-title":"J. Am. Chem. Soc."},{"issue":"34","key":"D5RA05474E\/cit12\/1","doi-asserted-by":"crossref","first-page":"6473","DOI":"10.1002\/anie.200701271","volume":"46","author":"Liu","year":"2007","journal-title":"Angew Chem., Int. Ed."},{"issue":"4","key":"D5RA05474E\/cit13\/1","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1021\/ja0669070","volume":"129","author":"Zhou","year":"2007","journal-title":"J. Am. Chem. Soc."},{"issue":"4","key":"D5RA05474E\/cit14\/1","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/smll.200700578","volume":"4","author":"Bourlinos","year":"2008","journal-title":"Small"},{"issue":"25","key":"D5RA05474E\/cit15\/1","doi-asserted-by":"crossref","first-page":"4598","DOI":"10.1002\/anie.200900652","volume":"48","author":"Liu","year":"2009","journal-title":"Angew Chem., Int. Ed."},{"issue":"34","key":"D5RA05474E\/cit16\/1","doi-asserted-by":"crossref","first-page":"5118","DOI":"10.1039\/b907612c","author":"Zhu","year":"2009","journal-title":"Chem. Commun."},{"issue":"28","key":"D5RA05474E\/cit17\/1","doi-asserted-by":"crossref","first-page":"4411","DOI":"10.1002\/ejic.201000622","volume":"2010","author":"Zhang","year":"2010","journal-title":"Eur. J. Inorg. Chem."},{"issue":"17","key":"D5RA05474E\/cit18\/1","doi-asserted-by":"crossref","first-page":"5944","DOI":"10.1021\/ja1009376","volume":"132","author":"Yan","year":"2010","journal-title":"J. Am. Chem. Soc."},{"issue":"2","key":"D5RA05474E\/cit19\/1","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.carbon.2010.10.004","volume":"49","author":"Li","year":"2011","journal-title":"Carbon"},{"key":"D5RA05474E\/cit20\/1","doi-asserted-by":"crossref","first-page":"160429","DOI":"10.1016\/j.cej.2025.160429","volume":"507","author":"Chen","year":"2025","journal-title":"Chem. Eng. J."},{"key":"D5RA05474E\/cit21\/1","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s42114-023-00641-4","volume":"6","author":"Bai","year":"2023","journal-title":"Adv. Compos. Hybrid Mater."},{"issue":"5","key":"D5RA05474E\/cit22\/1","doi-asserted-by":"crossref","first-page":"4391","DOI":"10.1007\/s12274-023-6383-6","volume":"17","author":"Wang","year":"2024","journal-title":"Nano Res."},{"issue":"4","key":"D5RA05474E\/cit23\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.37188\/lam.2024.041","volume":"5","author":"Yu","year":"2024","journal-title":"Light Adv. Manuf."},{"issue":"19","key":"D5RA05474E\/cit24\/1","first-page":"23","volume":"69","author":"Liu","year":"2024","journal-title":"Sci. Bull."},{"key":"D5RA05474E\/cit25\/1","doi-asserted-by":"crossref","first-page":"143377","DOI":"10.1016\/j.foodchem.2025.143377","volume":"475","author":"Wang","year":"2025","journal-title":"Food Chem."},{"key":"D5RA05474E\/cit26\/1","doi-asserted-by":"crossref","first-page":"2509879","DOI":"10.1002\/adfm.202509879","author":"Pan","year":"2025","journal-title":"Adv. Funct. Mater."},{"issue":"1","key":"D5RA05474E\/cit27\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12951-017-0328-8","volume":"22","author":"Wu","year":"2024","journal-title":"J. Nanobiotechnol."},{"key":"D5RA05474E\/cit28\/1","doi-asserted-by":"crossref","first-page":"122622","DOI":"10.1016\/j.biomaterials.2024.122622","volume":"309","author":"Guo","year":"2024","journal-title":"Biomaterials"},{"issue":"7","key":"D5RA05474E\/cit29\/1","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1007\/s00604-024-06456-4","volume":"191","author":"Chen","year":"2024","journal-title":"Microchim. Acta"},{"key":"D5RA05474E\/cit30\/1","first-page":"11","volume":"481","author":"Gong","year":"2024","journal-title":"Chem. Eng. J."},{"issue":"22","key":"D5RA05474E\/cit31\/1","doi-asserted-by":"crossref","first-page":"e202403581","DOI":"10.1002\/anie.202403581","volume":"63","author":"Yang","year":"2024","journal-title":"Angew Chem. Int. Ed. Engl."},{"key":"D5RA05474E\/cit32\/1","doi-asserted-by":"crossref","first-page":"rbae120","DOI":"10.1093\/rb\/rbae120","volume":"11","author":"Zhang","year":"2024","journal-title":"Regener. Biomater."},{"issue":"3","key":"D5RA05474E\/cit33\/1","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1021\/acsagscitech.2c00088","volume":"2","author":"Huang","year":"2022","journal-title":"ACS Agric. Sci. Technol."},{"issue":"30","key":"D5RA05474E\/cit34\/1","doi-asserted-by":"crossref","first-page":"39090","DOI":"10.1021\/acsami.4c07607","volume":"16","author":"Xu","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D5RA05474E\/cit35\/1","doi-asserted-by":"crossref","first-page":"111871","DOI":"10.1016\/j.intimp.2024.111871","volume":"131","author":"Peng","year":"2024","journal-title":"Int. Immunopharmacol."},{"issue":"45","key":"D5RA05474E\/cit36\/1","doi-asserted-by":"crossref","first-page":"2403160","DOI":"10.1002\/smll.202403160","volume":"20","author":"Wang","year":"2024","journal-title":"Small"},{"issue":"37","key":"D5RA05474E\/cit37\/1","doi-asserted-by":"crossref","first-page":"19739","DOI":"10.1021\/acs.langmuir.4c02481","volume":"40","author":"Jia","year":"2024","journal-title":"Langmuir"},{"issue":"33","key":"D5RA05474E\/cit38\/1","doi-asserted-by":"crossref","first-page":"43189","DOI":"10.1021\/acsami.4c02955","volume":"16","author":"Chen","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D5RA05474E\/cit39\/1","doi-asserted-by":"crossref","first-page":"156389","DOI":"10.1016\/j.cej.2024.156389","volume":"499","author":"Wang","year":"2024","journal-title":"Chem. Eng. J."},{"key":"D5RA05474E\/cit40\/1","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.jcis.2024.01.039","volume":"659","author":"Zhang","year":"2024","journal-title":"J. Colloid Interface Sci."},{"issue":"45","key":"D5RA05474E\/cit41\/1","doi-asserted-by":"crossref","first-page":"2406096","DOI":"10.1002\/adfm.202406096","volume":"34","author":"Cai","year":"2024","journal-title":"Adv. Funct. Mater."},{"issue":"11","key":"D5RA05474E\/cit42\/1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1021\/acsnano.3c12580","volume":"18","author":"Xin","year":"2024","journal-title":"ACS Nano"},{"issue":"48","key":"D5RA05474E\/cit43\/1","doi-asserted-by":"crossref","first-page":"2405629","DOI":"10.1002\/adfm.202405629","volume":"34","author":"Duan","year":"2024","journal-title":"Adv. Funct. Mater."},{"key":"D5RA05474E\/cit44\/1","doi-asserted-by":"crossref","first-page":"152842","DOI":"10.1016\/j.cej.2024.152842","volume":"493","author":"Zhang","year":"2024","journal-title":"Chem. Eng. J."},{"key":"D5RA05474E\/cit45\/1","first-page":"9","volume":"462","author":"Gao","year":"2023","journal-title":"Chem. Eng. J."},{"key":"D5RA05474E\/cit46\/1","doi-asserted-by":"crossref","first-page":"2507840","DOI":"10.1002\/adfm.202507840","author":"Chen","year":"2025","journal-title":"Adv. Funct. Mater."},{"issue":"33","key":"D5RA05474E\/cit47\/1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1021\/acsnano.4c05266","volume":"18","author":"Nie","year":"2024","journal-title":"ACS Nano"},{"issue":"24","key":"D5RA05474E\/cit48\/1","doi-asserted-by":"crossref","first-page":"2418683","DOI":"10.1002\/adfm.202418683","volume":"35","author":"Deng","year":"2025","journal-title":"Adv. Funct. Mater."},{"issue":"22","key":"D5RA05474E\/cit49\/1","doi-asserted-by":"crossref","first-page":"2418407","DOI":"10.1002\/adfm.202418407","volume":"35","author":"Li","year":"2025","journal-title":"Adv. Funct. Mater."},{"issue":"1","key":"D5RA05474E\/cit50\/1","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1186\/s12951-025-03477-w","volume":"23","author":"Guo","year":"2025","journal-title":"J. Nanobiotechnol."},{"key":"D5RA05474E\/cit51\/1","doi-asserted-by":"crossref","first-page":"162637","DOI":"10.1016\/j.cej.2025.162637","volume":"513","author":"Yang","year":"2025","journal-title":"Chem. Eng. J."},{"key":"D5RA05474E\/cit52\/1","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.jcis.2023.07.124","volume":"651","author":"Silva","year":"2023","journal-title":"J. Colloid Interface Sci."},{"key":"D5RA05474E\/cit53\/1","doi-asserted-by":"crossref","first-page":"142886","DOI":"10.1016\/j.foodchem.2025.142886","volume":"472","author":"Wang","year":"2025","journal-title":"Food Chem."},{"issue":"40","key":"D5RA05474E\/cit54\/1","doi-asserted-by":"crossref","first-page":"2406681","DOI":"10.1002\/advs.202406681","volume":"11","author":"He","year":"2024","journal-title":"Adv. Sci."},{"issue":"3","key":"D5RA05474E\/cit55\/1","doi-asserted-by":"crossref","first-page":"2400435","DOI":"10.1002\/sstr.202400435","volume":"6","author":"Shi","year":"2025","journal-title":"Small Struct."},{"issue":"12","key":"D5RA05474E\/cit56\/1","doi-asserted-by":"crossref","first-page":"2414237","DOI":"10.1002\/adma.202414237","volume":"37","author":"Li","year":"2025","journal-title":"Adv. Mater."},{"issue":"6","key":"D5RA05474E\/cit57\/1","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1021\/acs.chemmater.5c00037","volume":"37","author":"Shi","year":"2025","journal-title":"Chem. Mater."}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/RA\/D5RA05474E","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T03:28:05Z","timestamp":1782876485000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ra\/article\/15\/42\/35421-35435\/908007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":57,"journal-issue":{"issue":"42","published-print":{"date-parts":[[2025,9,22]]}},"URL":"https:\/\/doi.org\/10.1039\/d5ra05474e","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D5RA05474E\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05474E\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05474E\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05474E\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05474E\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05474E\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05474E\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05474E\/v1\/decision1","asserted-by":"object"}]},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}