{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T15:56:15Z","timestamp":1792252575778,"version":"4.4.0"},"reference-count":63,"publisher":"Royal Society of Chemistry (RSC)","issue":"48","license":[{"start":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000},"content-version":"vor","delay-in-days":299,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<jats:p>Chronic wounds pose a global challenge, often requiring the use of multifunctional materials that facilitate healing while protecting against infection.<\/jats:p>","DOI":"10.1039\/d5ra05550d","type":"journal-article","created":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T09:49:02Z","timestamp":1761558542000},"page":"40745-40759","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Citric acid cross-linked honey and aloe vera gel loaded chitosan hydrogels for wound dressing applications"],"prefix":"10.1039","volume":"15","author":[{"given":"Sohail","family":"Shahzad","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Sahiwal, Sahiwal 57000, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghulam","family":"Ghouse","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Sahiwal, Sahiwal 57000, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3889-9977","authenticated-orcid":false,"given":"Muhammad","family":"Zubair","sequence":"additional","affiliation":[{"name":"Lipids\/Materials Chemistry Group (LMCG), Department of Agricultural, Food and Nutritional Science (AFNS), University of Alberta, Edmonton, AB, T6G 2P5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma","family":"Yaqoob","sequence":"additional","affiliation":[{"name":"Institute of Biochemistry, Biotechnology and Bioinformatics, The Islamia University of Bahawalpur, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2585-7086","authenticated-orcid":false,"given":"Maria","family":"Mujahid","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Sahiwal, Sahiwal 57000, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9349-0525","authenticated-orcid":false,"given":"Faiz","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Government College University Faisalabad, Faisalabad 37000, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahid","family":"Rauf","sequence":"additional","affiliation":[{"name":"Pakistan Forest Institute (PFI), Peshawar, Khyber Pakhtunkhwa 25130, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1801-0162","authenticated-orcid":false,"given":"Aman","family":"Ullah","sequence":"additional","affiliation":[{"name":"Lipids\/Materials Chemistry Group (LMCG), Department of Agricultural, Food and Nutritional Science (AFNS), University of Alberta, Edmonton, AB, T6G 2P5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D5RA05550D\/cit1\/1","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1039\/D4BM01099J","volume":"13","author":"Zubair","year":"2025","journal-title":"Biomater. Sci."},{"key":"D5RA05550D\/cit2\/1","doi-asserted-by":"crossref","first-page":"109442","DOI":"10.1016\/j.cclet.2023.109442","volume":"35","author":"Liang","year":"2024","journal-title":"Chin. Chem. Lett."},{"key":"D5RA05550D\/cit3\/1","doi-asserted-by":"crossref","first-page":"495","DOI":"10.3390\/gels10080495","volume":"10","author":"Zhu","year":"2024","journal-title":"Gels"},{"key":"D5RA05550D\/cit4\/1","doi-asserted-by":"crossref","first-page":"e7328","DOI":"10.1002\/aoc.7328","volume":"38","author":"Yang","year":"2024","journal-title":"Appl. Organomet. Chem."},{"key":"D5RA05550D\/cit5\/1","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1021\/acsbiomaterials.4c02054","volume":"11","author":"Liang","year":"2025","journal-title":"ACS Biomater. Sci. Eng."},{"key":"D5RA05550D\/cit6\/1","doi-asserted-by":"crossref","first-page":"113026","DOI":"10.1016\/j.eurpolymj.2024.113026","author":"Duarte","year":"2024","journal-title":"Eur. Polym. J."},{"key":"D5RA05550D\/cit7\/1","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.3390\/polym17152026","volume":"17","author":"Segneanu","year":"2025","journal-title":"Polymers"},{"key":"D5RA05550D\/cit8\/1","doi-asserted-by":"crossref","first-page":"e54746","DOI":"10.1002\/app.54746","volume":"141","author":"Zhang","year":"2024","journal-title":"J. Appl. Polym. Sci."},{"key":"D5RA05550D\/cit9\/1","doi-asserted-by":"crossref","first-page":"131207","DOI":"10.1016\/j.ijbiomac.2024.131207","author":"Sadeghianmaryan","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D5RA05550D\/cit10\/1","doi-asserted-by":"crossref","first-page":"146070","DOI":"10.1016\/j.ijbiomac.2025.146070","author":"Zubair","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"D5RA05550D\/cit11\/1","doi-asserted-by":"crossref","first-page":"103267","DOI":"10.1016\/j.cis.2024.103267","author":"Zhang","year":"2024","journal-title":"Adv. Colloid Interface Sci."},{"key":"D5RA05550D\/cit12\/1","doi-asserted-by":"crossref","first-page":"e57827","DOI":"10.1002\/app.57827","author":"Kaushik","year":"2025","journal-title":"J. Appl. Polym. Sci."},{"key":"D5RA05550D\/cit13\/1","doi-asserted-by":"crossref","first-page":"128831","DOI":"10.1016\/j.ijbiomac.2023.128831","volume":"258","author":"Amir","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D5RA05550D\/cit14\/1","first-page":"45","volume-title":"Green Biopolymers for Packaging Applications","author":"Shahzad","year":"2025","unstructured":"S.Shahzad  and  M.Mujahid , in  Green Biopolymers for Packaging Applications ,  CRC Press ,  2025 ,  pp. 45\u201377"},{"key":"D5RA05550D\/cit15\/1","doi-asserted-by":"crossref","first-page":"025021","DOI":"10.1088\/1748-605X\/ad1df9","volume":"19","author":"Ding","year":"2024","journal-title":"Biomed. Mater."},{"key":"D5RA05550D\/cit16\/1","doi-asserted-by":"crossref","first-page":"129972","DOI":"10.1016\/j.matchemphys.2024.129972","volume":"328","author":"Elabbasy","year":"2024","journal-title":"Mater. Chem. Phys."},{"key":"D5RA05550D\/cit17\/1","first-page":"45","volume-title":"Green Biopolymers for Packaging Applications","author":"Shahzad","unstructured":"S.Shahzad  and  M.Mujahid , in  Green Biopolymers for Packaging Applications ,  CRC Press , pp. ,  pp. 45\u201377"},{"key":"D5RA05550D\/cit18\/1","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.3390\/nu16152455","volume":"16","author":"Tang","year":"2024","journal-title":"Nutrients"},{"key":"D5RA05550D\/cit19\/1","doi-asserted-by":"crossref","first-page":"e2251","DOI":"10.1002\/hsr2.2251","volume":"7","author":"Chin","year":"2024","journal-title":"Health Sci. Rep."},{"issue":"12","key":"D5RA05550D\/cit20\/1","doi-asserted-by":"crossref","first-page":"8642","DOI":"10.1021\/acsabm.4c01449","volume":"7","author":"Kheradvar Kolour","year":"2024","journal-title":"ACS Appl. Bio Mater."},{"key":"D5RA05550D\/cit21\/1","first-page":"812","volume":"4","author":"Rahmania","year":"2024","journal-title":"Int. J. Med. Sci."},{"key":"D5RA05550D\/cit22\/1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/0976500X241237361","volume":"15","author":"Naskar","year":"2024","journal-title":"J. Pharmacol. Pharmacother."},{"key":"D5RA05550D\/cit23\/1","doi-asserted-by":"crossref","first-page":"112879","DOI":"10.1016\/j.inoche.2024.112879","volume":"168","author":"Khamene","year":"2024","journal-title":"Inorg. Chem. Commun."},{"key":"D5RA05550D\/cit24\/1","doi-asserted-by":"crossref","first-page":"e35379","DOI":"10.1002\/jbm.b.35379","volume":"112","author":"Ceballos-Santa","year":"2024","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"key":"D5RA05550D\/cit25\/1","first-page":"12","volume":"7","author":"Muslim","year":"2024","journal-title":"Int. J. Adv. Life sci. Res."},{"key":"D5RA05550D\/cit26\/1","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.carbpol.2018.06.114","volume":"199","author":"Hamedi","year":"2018","journal-title":"Carbohydr. Polym."},{"key":"D5RA05550D\/cit27\/1","doi-asserted-by":"crossref","first-page":"106262","DOI":"10.1016\/j.foodhyd.2020.106262","volume":"111","author":"Kuo","year":"2021","journal-title":"Food Hydrocoll."},{"key":"D5RA05550D\/cit28\/1","doi-asserted-by":"crossref","first-page":"122827","DOI":"10.1016\/j.carbpol.2024.122827","volume":"348","author":"Li","year":"2025","journal-title":"Carbohydr. Polym."},{"key":"D5RA05550D\/cit29\/1","doi-asserted-by":"crossref","first-page":"133366","DOI":"10.1016\/j.ijbiomac.2024.133366","volume":"274","author":"Savekar","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D5RA05550D\/cit30\/1","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.ejpb.2018.02.022","volume":"127","author":"Sim\u00f5es","year":"2018","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"D5RA05550D\/cit31\/1","first-page":"100528","volume":"15","author":"Islam","year":"2024","journal-title":"Compos., Part C: Open Access"},{"key":"D5RA05550D\/cit32\/1","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/j.carbpol.2010.08.077","volume":"83","author":"Chhatri","year":"2011","journal-title":"Carbohydr. Polym."},{"key":"D5RA05550D\/cit33\/1","doi-asserted-by":"crossref","first-page":"6435","DOI":"10.1007\/s13369-019-03937-0","volume":"44","author":"Shahzadi","year":"2019","journal-title":"Arabian J. Sci. Eng."},{"issue":"11","key":"D5RA05550D\/cit34\/1","doi-asserted-by":"crossref","first-page":"7391","DOI":"10.1021\/acsabm.4c01044","volume":"7","author":"Mir","year":"2024","journal-title":"ACS Appl. Bio Mater."},{"key":"D5RA05550D\/cit35\/1","doi-asserted-by":"crossref","first-page":"439","DOI":"10.3390\/bioengineering12050439","volume":"12","author":"Mujahid","year":"2025","journal-title":"Bioengineering"},{"key":"D5RA05550D\/cit36\/1","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1016\/j.ijbiomac.2020.02.048","volume":"149","author":"Kumar","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"D5RA05550D\/cit37\/1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1089\/ten.teb.2009.0639","volume":"16","author":"Annabi","year":"2010","journal-title":"Tissue Engineering Part B: Reviews"},{"key":"D5RA05550D\/cit38\/1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.carbpol.2009.11.039","volume":"80","author":"Shalumon","year":"2010","journal-title":"Carbohydr. Polym."},{"key":"D5RA05550D\/cit39\/1","doi-asserted-by":"crossref","first-page":"46311","DOI":"10.1002\/app.46311","volume":"135","author":"Noori","year":"2018","journal-title":"J. Appl. Polym. Sci."},{"key":"D5RA05550D\/cit40\/1","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.3390\/pharmaceutics15071913","volume":"15","author":"Bai","year":"2023","journal-title":"Pharmaceutics"},{"key":"D5RA05550D\/cit41\/1","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.tifs.2021.07.035","volume":"116","author":"Maan","year":"2021","journal-title":"Trends Food Sci. Technol."},{"key":"D5RA05550D\/cit42\/1","doi-asserted-by":"crossref","first-page":"119520","DOI":"10.1016\/j.carbpol.2022.119520","volume":"291","author":"Chang","year":"2022","journal-title":"Carbohydr. Polym."},{"key":"D5RA05550D\/cit43\/1","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.carbpol.2008.04.045","volume":"74","author":"Shi","year":"2008","journal-title":"Carbohydr. Polym."},{"key":"D5RA05550D\/cit44\/1","doi-asserted-by":"crossref","first-page":"e55303","DOI":"10.1002\/app.55303","volume":"141","author":"Shamsuri","year":"2024","journal-title":"J. Appl. Polym. Sci."},{"key":"D5RA05550D\/cit45\/1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.17488\/RMIB.44.3.2","volume":"44","author":"Chapa","year":"2023","journal-title":"Rev. Mexic. Ingen. Biomed."},{"key":"D5RA05550D\/cit46\/1","doi-asserted-by":"crossref","first-page":"7247","DOI":"10.1007\/s00289-022-04443-4","volume":"80","author":"Das","year":"2023","journal-title":"Polym. Bull."},{"key":"D5RA05550D\/cit47\/1","doi-asserted-by":"crossref","first-page":"527","DOI":"10.3390\/gels10080527","volume":"10","author":"Mahamoud","year":"2024","journal-title":"Gels"},{"key":"D5RA05550D\/cit48\/1","author":"Biscari","year":"2023","unstructured":"G.Biscari ,  2023"},{"key":"D5RA05550D\/cit49\/1","first-page":"101","volume-title":"Chronic Wound Care Management and Research","author":"Wiegand","year":"2015","unstructured":"C.Wiegand ,  J.Tittelbach ,  U.-C.Hipler  and  P.Elsner ,  Chronic Wound Care Management and Research ,  2015 ,  101\u2013111"},{"key":"D5RA05550D\/cit50\/1","doi-asserted-by":"crossref","first-page":"127793","DOI":"10.1016\/j.seppur.2024.127793","volume":"350","author":"Pochampally","year":"2024","journal-title":"Sep. Purif. Technol."},{"key":"D5RA05550D\/cit51\/1","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1039\/D4BM01099J","volume":"13","author":"Zubair","year":"2025","journal-title":"Biomater. Sci."},{"key":"D5RA05550D\/cit52\/1","doi-asserted-by":"crossref","first-page":"12687","DOI":"10.1021\/acsnano.1c04206","volume":"15","author":"Liang","year":"2021","journal-title":"ACS Nano"},{"key":"D5RA05550D\/cit53\/1","doi-asserted-by":"crossref","first-page":"110271","DOI":"10.1016\/j.eurpolymj.2021.110271","volume":"146","author":"Salihu","year":"2021","journal-title":"Eur. Polym. J."},{"key":"D5RA05550D\/cit54\/1","doi-asserted-by":"crossref","first-page":"3080","DOI":"10.3390\/molecules27103080","volume":"27","author":"Esa","year":"2022","journal-title":"Molecules"},{"key":"D5RA05550D\/cit55\/1","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1038\/s41598-018-20006-y","volume":"8","author":"Yang","year":"2018","journal-title":"Sci. Rep."},{"key":"D5RA05550D\/cit56\/1","doi-asserted-by":"crossref","first-page":"11611","DOI":"10.1039\/D4TB01666A","volume":"12","author":"Zhang","year":"2024","journal-title":"J. Mater. Chem. B"},{"key":"D5RA05550D\/cit57\/1","doi-asserted-by":"crossref","first-page":"7449","DOI":"10.3390\/ijms22147449","volume":"22","author":"Ardean","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"D5RA05550D\/cit58\/1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3390\/jfb14020115","volume":"14","author":"Farasati Far","year":"2023","journal-title":"J. Funct. Biomater."},{"key":"D5RA05550D\/cit59\/1","doi-asserted-by":"crossref","first-page":"121408","DOI":"10.1016\/j.carbpol.2023.121408","volume":"323","author":"Patel","year":"2024","journal-title":"Carbohydr. Polym."},{"key":"D5RA05550D\/cit60\/1","doi-asserted-by":"crossref","first-page":"111218","DOI":"10.1016\/j.msec.2020.111218","volume":"116","author":"Mukhopadhyay","year":"2020","journal-title":"Mater. Sci. Eng. C"},{"key":"D5RA05550D\/cit61\/1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s43939-024-00080-y","volume":"4","author":"Dada","year":"2024","journal-title":"Discov. Mater."},{"key":"D5RA05550D\/cit63\/1","first-page":"117409","author":"Zhang","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"D5RA05550D\/cit64\/1","doi-asserted-by":"crossref","first-page":"135724","DOI":"10.1016\/j.ijbiomac.2024.135724","author":"Zhao","year":"2024","journal-title":"Int. J. Biol. Macromol."}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/RA\/D5RA05550D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T18:12:52Z","timestamp":1783275172000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ra\/article\/15\/48\/40745-40759\/908039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":63,"journal-issue":{"issue":"48","published-print":{"date-parts":[[2025,10,22]]}},"URL":"https:\/\/doi.org\/10.1039\/d5ra05550d","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D5RA05550D\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05550D\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05550D\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05550D\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05550D\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05550D\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05550D\/v1\/review2","asserted-by":"object"}]},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}