{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T05:54:04Z","timestamp":1782885244290,"version":"3.54.5"},"reference-count":65,"publisher":"Royal Society of Chemistry (RSC)","issue":"11","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"vor","delay-in-days":49,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100022334","name":"National Institute of Technology Hamirpur","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022334","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Adv."],"abstract":"<jats:p>Interaction between Protic Ionic Liquids (PIL) and mitoxantrone (MTX) using different techniques.<\/jats:p>","DOI":"10.1039\/d5ra05841d","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T08:30:08Z","timestamp":1771489808000},"page":"9779-9795","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Decoding the interplay between protic ionic liquids and drug: spectrophotometric, electrochemical, and DFT exploration of mitoxantrone"],"prefix":"10.1039","volume":"16","author":[{"given":"Arti","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Chemistry, National Institute of Technology, Hamirpur-177005, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8152-6909","authenticated-orcid":false,"given":"Ravinder","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Chemistry, National Institute of Technology, Hamirpur-177005, India"},{"name":"Department of Chemistry, Dr B R Ambedkar National Institute of Technology, Jalandhar-144011, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Ritu","sequence":"additional","affiliation":[{"name":"Department of Chemistry, National Institute of Technology, Hamirpur-177005, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4305-0182","authenticated-orcid":false,"given":"Pamita","family":"Awasthi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, National Institute of Technology, Hamirpur-177005, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2906-473X","authenticated-orcid":false,"given":"Indra","family":"Bahadur","sequence":"additional","affiliation":[{"name":"Department of Chemistry, North-West University, Mafikeng Campus, Mmabatho 2735, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"issue":"6","key":"D5RA05841D\/cit1\/1","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1021\/acs.molpharmaceut.8b00305","volume":"15","author":"Chowdhury","year":"2018","journal-title":"Mol. Pharm."},{"issue":"15","key":"D5RA05841D\/cit2\/1","doi-asserted-by":"crossref","first-page":"3454","DOI":"10.1002\/cphc.201300509","volume":"14","author":"Zhang","year":"2013","journal-title":"Chem. Phys. Chem."},{"issue":"14","key":"D5RA05841D\/cit3\/1","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1039\/C3CC48650H","volume":"50","author":"Williams","year":"2014","journal-title":"Chem. Commun."},{"issue":"10","key":"D5RA05841D\/cit4\/1","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1021\/acs.jced.2c00319","volume":"67","author":"Amirchand","year":"2022","journal-title":"J. Chem. Eng. Data"},{"issue":"51","key":"D5RA05841D\/cit5\/1","doi-asserted-by":"crossref","first-page":"12960","DOI":"10.1021\/acs.iecr.5b03367","volume":"54","author":"Akinlua","year":"2015","journal-title":"Ind. Eng. Chem. Res."},{"key":"D5RA05841D\/cit6\/1","doi-asserted-by":"crossref","first-page":"3637","DOI":"10.1007\/s00289-019-02929-2","volume":"77","author":"Dias","year":"2020","journal-title":"Polym. Bull."},{"issue":"13","key":"D5RA05841D\/cit7\/1","doi-asserted-by":"crossref","first-page":"3220","DOI":"10.1021\/acs.jpcb.3c08069","volume":"128","author":"McGrogan","year":"2024","journal-title":"J. Phys. Chem. B"},{"issue":"45","key":"D5RA05841D\/cit8\/1","doi-asserted-by":"crossref","first-page":"22479","DOI":"10.1021\/jp0634048","volume":"110","author":"Greaves","year":"2006","journal-title":"J. Phys. Chem. B"},{"key":"D5RA05841D\/cit9\/1","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.biortech.2016.11.019","volume":"224","author":"Reis","year":"2017","journal-title":"Bioresour. Technol."},{"key":"D5RA05841D\/cit10\/1","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1007\/s10311-020-01057-y","volume":"18","author":"Krishnan","year":"2020","journal-title":"Chem. Lett."},{"key":"D5RA05841D\/cit11\/1","doi-asserted-by":"crossref","first-page":"114345","DOI":"10.1016\/j.ejpb.2024.114345","volume":"201","author":"Reis","year":"2024","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"D5RA05841D\/cit12\/1","doi-asserted-by":"crossref","first-page":"118845","DOI":"10.1016\/j.molliq.2022.118845","volume":"354","author":"Amirchand","year":"2022","journal-title":"J. Mol. Liq."},{"issue":"51","key":"D5RA05841D\/cit13\/1","doi-asserted-by":"crossref","first-page":"12960","DOI":"10.1021\/acs.iecr.5b03367","volume":"54","author":"Akinlua","year":"2015","journal-title":"Eng. Chem. Res."},{"issue":"1\u20132","key":"D5RA05841D\/cit14\/1","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.ijpharm.2010.08.034","volume":"400","author":"Moniruzzaman","year":"2010","journal-title":"Int. J. Pharm."},{"key":"D5RA05841D\/cit15\/1","first-page":"311","author":"Tan","year":"2010","journal-title":"Ionic Liq."},{"issue":"6","key":"D5RA05841D\/cit16\/1","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1021\/ja017593d","volume":"124","author":"Bates","year":"2002","journal-title":"J. Am. Chem. Soc."},{"issue":"2","key":"D5RA05841D\/cit17\/1","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.jpowsour.2009.06.089","volume":"194","author":"Lewandowski","year":"2009","journal-title":"J. Power Sources"},{"key":"D5RA05841D\/cit18\/1","doi-asserted-by":"crossref","first-page":"112563","DOI":"10.1016\/j.indcrop.2020.112563","volume":"152","author":"Fan","year":"2020","journal-title":"Ind. Crops Prod."},{"issue":"41","key":"D5RA05841D\/cit19\/1","doi-asserted-by":"crossref","first-page":"6744","DOI":"10.1039\/C5CC10120D","volume":"52","author":"Dong","year":"2016","journal-title":"Chem. Commun."},{"key":"D5RA05841D\/cit20\/1","doi-asserted-by":"crossref","first-page":"106779","DOI":"10.1016\/j.jct.2022.106779","volume":"170","author":"Sedov","year":"2022","journal-title":"J. Chem. Thermodyn."},{"key":"D5RA05841D\/cit21\/1","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.chemosphere.2015.11.016","volume":"147","author":"Oliveira","year":"2016","journal-title":"Chemosphere"},{"issue":"44","key":"D5RA05841D\/cit22\/1","doi-asserted-by":"crossref","first-page":"11762","DOI":"10.1002\/anie.201404402","volume":"53","author":"Chen","year":"2014","journal-title":"Angew. Chem., Int. Ed."},{"issue":"14","key":"D5RA05841D\/cit23\/1","doi-asserted-by":"crossref","first-page":"4966","DOI":"10.1039\/c2cs35151j","volume":"41","author":"Freire","year":"2012","journal-title":"Chem. Soc. Rev."},{"issue":"12","key":"D5RA05841D\/cit24\/1","doi-asserted-by":"crossref","first-page":"4232","DOI":"10.1002\/aic.14634","volume":"60","author":"Huang","year":"2014","journal-title":"AIChE J."},{"issue":"57","key":"D5RA05841D\/cit25\/1","doi-asserted-by":"crossref","first-page":"35806","DOI":"10.1039\/D1RA05686G","volume":"11","author":"Malik","year":"2021","journal-title":"RSC Adv."},{"key":"D5RA05841D\/cit26\/1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S1572-5995(05)80036-5","volume":"30","author":"Mart\u00ednez","year":"2005","journal-title":"Stud. Nat. Prod. Chem."},{"key":"D5RA05841D\/cit27\/1","doi-asserted-by":"crossref","first-page":"138317","DOI":"10.1016\/j.molstruc.2024.138317","volume":"1310","author":"Mehnati","year":"2024","journal-title":"J. Mol. Struct."},{"issue":"5","key":"D5RA05841D\/cit28\/1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.ejps.2008.07.010","volume":"35","author":"Khan","year":"2008","journal-title":"Eur. J. Pharm. Sci."},{"key":"D5RA05841D\/cit29\/1","doi-asserted-by":"crossref","first-page":"107069","DOI":"10.1016\/j.jct.2023.107069","volume":"184","author":"Amirchand","year":"2023","journal-title":"J. Chem. Thermodyn."},{"key":"D5RA05841D\/cit30\/1","doi-asserted-by":"crossref","first-page":"121803","DOI":"10.1016\/j.saa.2022.121803","volume":"285","author":"Siddiquee","year":"2023","journal-title":"Spectrochim. Acta, Part A"},{"issue":"4","key":"D5RA05841D\/cit31\/1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s12039-022-02090-w","volume":"134","author":"Sharma","year":"2022","journal-title":"J. Chem. Sci."},{"key":"D5RA05841D\/cit32\/1","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1007\/s10953-018-0739-7","volume":"47","author":"Farooq","year":"2008","journal-title":"J. Solution Chem."},{"key":"D5RA05841D\/cit33\/1","doi-asserted-by":"crossref","first-page":"124631","DOI":"10.1016\/j.molliq.2024.124631","volume":"401","author":"Kumar","year":"2024","journal-title":"J. Mol. Liq."},{"issue":"1\u20133","key":"D5RA05841D\/cit34\/1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.colsurfa.2004.02.013","volume":"237","author":"Mahajan","year":"2004","journal-title":"Colloids Surf., A"},{"issue":"50","key":"D5RA05841D\/cit35\/1","doi-asserted-by":"crossref","first-page":"17238","DOI":"10.1021\/la303193n","volume":"28","author":"Mahajan","year":"2012","journal-title":"Langmuir"},{"issue":"68","key":"D5RA05841D\/cit36\/1","doi-asserted-by":"crossref","first-page":"36286","DOI":"10.1039\/C4RA06083K","volume":"4","author":"Huang","year":"2014","journal-title":"RSC Adv."},{"key":"D5RA05841D\/cit37\/1","doi-asserted-by":"crossref","first-page":"115159","DOI":"10.1016\/j.molliq.2020.115159","volume":"325","author":"Kumar","year":"2021","journal-title":"J. Mol. Liq."},{"key":"D5RA05841D\/cit38\/1","doi-asserted-by":"crossref","first-page":"126457","DOI":"10.1016\/j.molliq.2024.126457","volume":"416","author":"Sharma","year":"2024","journal-title":"J. Mol. Liq."},{"issue":"3","key":"D5RA05841D\/cit39\/1","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1021\/acs.jced.4c00637","volume":"70","author":"Sharma","year":"2025","journal-title":"J. Chem. Eng. Data"},{"key":"D5RA05841D\/cit40\/1","doi-asserted-by":"crossref","first-page":"129293","DOI":"10.1016\/j.molstruc.2020.129293","volume":"1223","author":"Awasthi","year":"2021","journal-title":"J. Mol. Struct."},{"key":"D5RA05841D\/cit41\/1","doi-asserted-by":"crossref","first-page":"124403","DOI":"10.1016\/j.molliq.2024.124403","volume":"399","author":"Matczuk","year":"2024","journal-title":"J. Mol. Liq."},{"key":"D5RA05841D\/cit42\/1","first-page":"702","volume":"15","author":"Shukla","year":"2023","journal-title":"Pharm."},{"issue":"17","key":"D5RA05841D\/cit43\/1","doi-asserted-by":"crossref","first-page":"2004819","DOI":"10.1002\/advs.202004819","volume":"8","author":"Curreri","year":"2021","journal-title":"Adv. Sci."},{"key":"D5RA05841D\/cit44\/1","doi-asserted-by":"crossref","first-page":"14632","DOI":"10.1039\/D4RA08188A","volume":"15","author":"Ting","year":"2025","journal-title":"RSC Adv."},{"key":"D5RA05841D\/cit45\/1","doi-asserted-by":"crossref","first-page":"113342","DOI":"10.1016\/j.molliq.2020.113342","volume":"314","author":"Yuan","year":"2020","journal-title":"J. Mol. Liq."},{"key":"D5RA05841D\/cit46\/1","first-page":"118845","volume":"354","author":"Amirchand","year":"2022","journal-title":"J. Chem. Eng. Data"},{"issue":"3\u20134","key":"D5RA05841D\/cit47\/1","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1007\/s10953-015-0313-5","volume":"44","author":"Singh","year":"2015","journal-title":"J. Solution Chem."},{"issue":"45","key":"D5RA05841D\/cit48\/1","doi-asserted-by":"crossref","first-page":"22479","DOI":"10.1021\/jp0634048","volume":"110","author":"Greaves","year":"2006","journal-title":"J. Phys. Chem. B"},{"key":"D5RA05841D\/cit49\/1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jct.2007.05.011","volume":"40","author":"Iglesias","year":"2008","journal-title":"J. Chem. Thermodyn."},{"key":"D5RA05841D\/cit50\/1","doi-asserted-by":"crossref","first-page":"12468","DOI":"10.1021\/jp073963u","volume":"111","author":"Cota","year":"2007","journal-title":"J. Phys. Chem. B"},{"issue":"2","key":"D5RA05841D\/cit51\/1","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1021\/je900550v","volume":"55","author":"Alvarez","year":"2010","journal-title":"J. Chem. Eng. Data"},{"issue":"18","key":"D5RA05841D\/cit52\/1","doi-asserted-by":"crossref","first-page":"4926","DOI":"10.1021\/jp067589u","volume":"111","author":"Belieres","year":"2007","journal-title":"J. Phys. Chem. B"},{"issue":"3","key":"D5RA05841D\/cit53\/1","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.bpc.2005.04.009","volume":"116","author":"Li","year":"2005","journal-title":"Biophys. Chem."},{"key":"D5RA05841D\/cit54\/1","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.molliq.2016.07.076","volume":"222","author":"Pal","year":"2016","journal-title":"J. Mol. Liq."},{"issue":"42","key":"D5RA05841D\/cit55\/1","doi-asserted-by":"crossref","first-page":"12306","DOI":"10.1021\/jp2071925","volume":"115","author":"Shu","year":"2011","journal-title":"J. Phys. Chem. B"},{"issue":"64","key":"D5RA05841D\/cit56\/1","doi-asserted-by":"crossref","first-page":"38873","DOI":"10.1039\/D0RA06323A","volume":"10","author":"Sharma","year":"2020","journal-title":"RSC Adv."},{"issue":"45","key":"D5RA05841D\/cit57\/1","doi-asserted-by":"crossref","first-page":"42699","DOI":"10.1021\/acsomega.3c05100","volume":"8","author":"Siddiquee","year":"2023","journal-title":"ACS Omega"},{"issue":"1\u20133","key":"D5RA05841D\/cit58\/1","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0003-2670(98)00807-1","volume":"385","author":"Brett","year":"1999","journal-title":"Anal. Chim. Acta"},{"issue":"4","key":"D5RA05841D\/cit59\/1","first-page":"469","volume":"25","author":"Erdem","year":"2001","journal-title":"Turk. J. Chem."},{"issue":"23","key":"D5RA05841D\/cit60\/1","doi-asserted-by":"crossref","first-page":"6923","DOI":"10.1021\/jp711804j","volume":"112","author":"Zhao","year":"2008","journal-title":"J. Phys. Chem. B"},{"issue":"2","key":"D5RA05841D\/cit61\/1","first-page":"153","volume":"1","author":"Murray","year":"2011","journal-title":"Wiley Interdiscip. Rev.:Comput. Mol. Sci."},{"issue":"3","key":"D5RA05841D\/cit62\/1","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s00894-006-0154-7","volume":"13","author":"Politzer","year":"2007","journal-title":"J. Mol. Model."},{"issue":"18","key":"D5RA05841D\/cit63\/1","doi-asserted-by":"crossref","first-page":"e202405487","DOI":"10.1002\/slct.202405487","volume":"10","author":"Zulfiqar","year":"2025","journal-title":"ChemistrySelect"},{"issue":"6","key":"D5RA05841D\/cit64\/1","doi-asserted-by":"crossref","first-page":"e17672","DOI":"10.1002\/aic.17672","volume":"68","author":"Huang","year":"2022","journal-title":"AIChE J."},{"issue":"45","key":"D5RA05841D\/cit65\/1","doi-asserted-by":"crossref","first-page":"42699","DOI":"10.1021\/acsomega.3c05100","volume":"8","author":"Siddiquee","year":"2023","journal-title":"ACS Omega"}],"container-title":["RSC Advances"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2026\/RA\/D5RA05841D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:38:31Z","timestamp":1782880711000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/ra\/article\/16\/11\/9779-9795\/908144"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":65,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,2,16]]}},"URL":"https:\/\/doi.org\/10.1039\/d5ra05841d","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D5RA05841D\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v4\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v4\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v4\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v4\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v3\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5RA05841D\/v3\/review1","asserted-by":"object"}]},"ISSN":["2046-2069"],"issn-type":[{"value":"2046-2069","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}