{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:59:33Z","timestamp":1789664373805,"version":"4.0.1"},"reference-count":49,"publisher":"Royal Society of Chemistry (RSC)","issue":"32","license":[{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"vor","delay-in-days":190,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100007709","name":"Michigan State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007709","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["K01AI168587"],"award-info":[{"award-number":["K01AI168587"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI146210"],"award-info":[{"award-number":["R01AI146210"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI182419"],"award-info":[{"award-number":["R01AI182419"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Chem. Sci."],"abstract":"<jats:p>\n                    Salmonella lipopolysaccharide outer core glycans were synthesized. Antisera generated by the bacteriophage Q\u03b2-outer core glycan conjugate in combination with thanatin, exhibited enhanced cytotoxicity toward multiple serovars of pathogenic\n                    <jats:italic>Salmonella<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1039\/d5sc03944d","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T07:40:58Z","timestamp":1752133258000},"page":"14710-14723","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Synthesis and immunological evaluation of the lipopolysaccharide outer core of\n                    <i>Salmonella<\/i>\n                    for potential broad-spectrum protection against multiple\n                    <i>Salmonella<\/i>\n                    serovars"],"prefix":"10.1039","volume":"16","author":[{"given":"Xingling","family":"Pan","sequence":"first","affiliation":[{"name":"Department of Chemistry, Michigan State University, 578 South Shaw Lane, East Lansing, MI 48824, USA"},{"name":"Institute for Quantitative Health Science & Engineering, Michigan State University, 578 South Shaw Lane, East Lansing, MI 48824, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting-An","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Michigan State University, 578 South Shaw Lane, East Lansing, MI 48824, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Shafieichaharberoud","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Michigan State University, 578 South Shaw Lane, East Lansing, MI 48824, USA"},{"name":"Institute for Quantitative Health Science & Engineering, Michigan State University, 578 South Shaw Lane, East Lansing, MI 48824, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon M.","family":"Tennant","sequence":"additional","affiliation":[{"name":"Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, 685 W. Baltimore St., Baltimore, MD 21201, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott M.","family":"Baliban","sequence":"additional","affiliation":[{"name":"Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, 685 W. Baltimore St., Baltimore, MD 21201, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6468-5526","authenticated-orcid":false,"given":"Xuefei","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Michigan State University, 578 South Shaw Lane, East Lansing, MI 48824, USA"},{"name":"Institute for Quantitative Health Science & Engineering, Michigan State University, 578 South Shaw Lane, East Lansing, MI 48824, USA"},{"name":"Department of Biomedical Engineering, Michigan State University, East Lansing, MI 48824, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D5SC03944D\/cit1\/1","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.jiph.2016.09.018","volume":"10","author":"Hung","year":"2017","journal-title":"J. Infect. Public Health"},{"key":"D5SC03944D\/cit2\/1","doi-asserted-by":"crossref","first-page":"3666","DOI":"10.3390\/ani13233666","volume":"13","author":"Galan-Relano","year":"2023","journal-title":"Animals"},{"key":"D5SC03944D\/cit3\/1","doi-asserted-by":"crossref","first-page":"863","DOI":"10.3390\/ijerph15050863","volume":"15","author":"Chlebicz","year":"2018","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"D5SC03944D\/cit4\/1","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/S1473-3099(17)30276-1","volume":"17","author":"Collaborators","year":"2017","journal-title":"Lancet Infect. Dis."},{"key":"D5SC03944D\/cit5\/1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2023.0157","volume":"21","author":"Hoffmann","year":"2024","journal-title":"Foodborne Pathog. Dis."},{"key":"D5SC03944D\/cit6\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12916-019-1443-1","volume":"18","author":"Browne","year":"2020","journal-title":"BMC Med."},{"key":"D5SC03944D\/cit7\/1","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1089\/fpd.2017.2283","volume":"14","author":"Karp","year":"2017","journal-title":"Foodborne Pathog. Dis."},{"key":"D5SC03944D\/cit8\/1","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1086\/529146","volume":"46","author":"Gordon","year":"2008","journal-title":"Clin. Infect. Dis."},{"key":"D5SC03944D\/cit9\/1","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1111\/j.1472-765X.2007.02133.x","volume":"44","author":"Bhatta","year":"2007","journal-title":"Lett. Appl. Microbiol."},{"key":"D5SC03944D\/cit10\/1","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1093\/cid\/ciw232","volume":"63","author":"Date","year":"2016","journal-title":"Clin. Infect. Dis."},{"key":"D5SC03944D\/cit11\/1","unstructured":"https:\/\/www.cdc.gov\/antimicrobial-resistance\/media\/pdfs\/2019-ar-threats-report-508.pdf , accessed May 15, 2025"},{"key":"D5SC03944D\/cit12\/1","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1136\/bmj.316.7125.110","volume":"316","author":"Engels","year":"1998","journal-title":"BMJ"},{"key":"D5SC03944D\/cit13\/1","doi-asserted-by":"crossref","first-page":"7848","DOI":"10.1016\/j.vaccine.2007.08.027","volume":"25","author":"Fraser","year":"2007","journal-title":"Vaccine"},{"key":"D5SC03944D\/cit14\/1","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1586\/erv.10.43","volume":"9","author":"Khan","year":"2010","journal-title":"Expert Rev. Vaccines"},{"key":"D5SC03944D\/cit15\/1","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1093\/cid\/civ295","volume":"61","author":"Mohan","year":"2015","journal-title":"Clin. Infect. Dis."},{"key":"D5SC03944D\/cit16\/1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S1473-3099(13)70241-X","volume":"14","author":"Bhutta","year":"2014","journal-title":"Lancet Infect. Dis."},{"key":"D5SC03944D\/cit17\/1","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1093\/ofid\/ofad041","volume":"10","author":"MacLennan","year":"2023","journal-title":"Open Forum Infect. Dis."},{"key":"D5SC03944D\/cit18\/1","doi-asserted-by":"crossref","first-page":"494","DOI":"10.4161\/hv.19158","volume":"8","author":"Simon","year":"2012","journal-title":"Hum. Vaccines Immunother."},{"key":"D5SC03944D\/cit19\/1","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.3389\/fimmu.2017.01647","volume":"8","author":"Li","year":"2017","journal-title":"Front. Immunol."},{"key":"D5SC03944D\/cit20\/1","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.4161\/hv.29054","volume":"10","author":"MacLennan","year":"2014","journal-title":"Hum. Vaccines Immunother."},{"key":"D5SC03944D\/cit21\/1","doi-asserted-by":"crossref","first-page":"4519","DOI":"10.1039\/C8CC08622B","volume":"55","author":"Huo","year":"2019","journal-title":"Chem. Commun."},{"key":"D5SC03944D\/cit22\/1","doi-asserted-by":"crossref","first-page":"15953","DOI":"10.1002\/chem.202002401","volume":"26","author":"Dhara","year":"2020","journal-title":"Chem.\u2013Eur. J."},{"key":"D5SC03944D\/cit23\/1","doi-asserted-by":"crossref","first-page":"e0004522","DOI":"10.1128\/mmbr.00045-22","volume":"87","author":"Cross","year":"2023","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"D5SC03944D\/cit24\/1","doi-asserted-by":"crossref","first-page":"4146","DOI":"10.1128\/IAI.05125-11","volume":"79","author":"Schmiel","year":"2011","journal-title":"Infect. Immun."},{"key":"D5SC03944D\/cit25\/1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0140-6736(96)06255-1","volume":"349","author":"Cohen","year":"1997","journal-title":"Lancet"},{"key":"D5SC03944D\/cit26\/1","doi-asserted-by":"crossref","first-page":"4545","DOI":"10.1128\/IAI.69.7.4545-4553.2001","volume":"69","author":"Fries","year":"2001","journal-title":"Infect. Immun."},{"key":"D5SC03944D\/cit27\/1","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1128\/CVI.00232-10","volume":"17","author":"Santos","year":"2010","journal-title":"Clin. Vaccine Immunol."},{"key":"D5SC03944D\/cit28\/1","doi-asserted-by":"crossref","first-page":"36470","DOI":"10.1074\/jbc.M401366200","volume":"279","author":"Kaniuk","year":"2004","journal-title":"J. Biol. Chem."},{"key":"D5SC03944D\/cit29\/1","volume-title":"Antigenic Formulae of the Salmonella Serovars","author":"Grimont","year":"2007","unstructured":"P. A. D.Grimont  and  F.-X.Weill , in  Antigenic Formulae of the Salmonella Serovars ,  Institut Pasteur ,  Paris , 9th edn,  2007 ,  https:\/\/www.pasteur.fr\/sites\/default\/files\/veng_0.pdf"},{"key":"D5SC03944D\/cit30\/1","doi-asserted-by":"crossref","first-page":"25618","DOI":"10.1074\/jbc.M302904200","volume":"278","author":"Muller-Loennies","year":"2003","journal-title":"J. Biol. Chem."},{"key":"D5SC03944D\/cit31\/1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1515\/BC.2008.056","volume":"389","author":"Nagy","year":"2008","journal-title":"Biol. Chem."},{"key":"D5SC03944D\/cit32\/1","doi-asserted-by":"publisher","first-page":"jiae641","DOI":"10.1093\/infdis\/jiae641","author":"Baliban","year":"2024","journal-title":"J. Infect. Dis."},{"key":"D5SC03944D\/cit33\/1","doi-asserted-by":"crossref","first-page":"6549","DOI":"10.1039\/D0OB01402H","volume":"18","author":"Zhao","year":"2020","journal-title":"Org. Biomol. Chem."},{"key":"D5SC03944D\/cit34\/1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.carres.2013.11.016","volume":"384","author":"Komarova","year":"2014","journal-title":"Carbohydr. Res."},{"key":"D5SC03944D\/cit35\/1","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1021\/ja982232s","volume":"121","author":"Zhang","year":"1999","journal-title":"J. Am. Chem. Soc."},{"key":"D5SC03944D\/cit36\/1","doi-asserted-by":"crossref","first-page":"e202201261","DOI":"10.1002\/ejoc.202201261","volume":"2022","author":"Njeri","year":"2022","journal-title":"Eur. J. Org. Chem."},{"key":"D5SC03944D\/cit37\/1","doi-asserted-by":"crossref","first-page":"6725","DOI":"10.1016\/S0040-4039(03)01647-2","volume":"44","author":"Imamura","year":"2003","journal-title":"Tetrahedron Lett."},{"key":"D5SC03944D\/cit38\/1","doi-asserted-by":"crossref","first-page":"e202203408","DOI":"10.1002\/chem.202203408","volume":"29","author":"Chen","year":"2023","journal-title":"Chem.\u2013Eur. J."},{"key":"D5SC03944D\/cit39\/1","doi-asserted-by":"crossref","first-page":"5221","DOI":"10.1002\/anie.200460176","volume":"43","author":"Huang","year":"2004","journal-title":"Angew. Chem., Int. Ed."},{"key":"D5SC03944D\/cit40\/1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1039\/p29740000293","author":"Bock","year":"1974","journal-title":"J. Chem. Soc., Perkin Trans. 2"},{"key":"D5SC03944D\/cit41\/1","doi-asserted-by":"crossref","first-page":"109270","DOI":"10.1016\/j.carres.2024.109270","volume":"545","author":"Pan","year":"2024","journal-title":"Carbohydr. Res."},{"key":"D5SC03944D\/cit42\/1","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.cbpa.2009.08.010","volume":"13","author":"Guo","year":"2009","journal-title":"Curr. Opin. Chem. Biol."},{"key":"D5SC03944D\/cit43\/1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1080\/07328303.2012.659364","volume":"31","author":"Yin","year":"2012","journal-title":"J. Carbohydr. Chem."},{"key":"D5SC03944D\/cit44\/1","doi-asserted-by":"crossref","first-page":"e202309744","DOI":"10.1002\/anie.202309744","volume":"62","author":"Rashidijahanabad","year":"2023","journal-title":"Angew. Chem., Int. Ed."},{"key":"D5SC03944D\/cit45\/1","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1021\/acs.bioconjchem.3c00415","volume":"35","author":"Shafieichaharberoud","year":"2024","journal-title":"Bioconjugate Chem."},{"key":"D5SC03944D\/cit46\/1","doi-asserted-by":"crossref","first-page":"3420","DOI":"10.1038\/s41467-024-47457-4","volume":"15","author":"Tan","year":"2024","journal-title":"Nat. Commun."},{"key":"D5SC03944D\/cit47\/1","doi-asserted-by":"crossref","first-page":"e305","DOI":"10.1038\/emm.2017.23","volume":"49","author":"Weber","year":"2017","journal-title":"Exp. Mol. Med."},{"key":"D5SC03944D\/cit48\/1","doi-asserted-by":"crossref","first-page":"eaau2634","DOI":"10.1126\/sciadv.aau2634","volume":"4","author":"Vetterli","year":"2018","journal-title":"Sci. Adv."},{"key":"D5SC03944D\/cit49\/1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/nchem.2432","volume":"8","author":"Kong","year":"2016","journal-title":"Nat. Chem."}],"container-title":["Chemical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/SC\/D5SC03944D","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:04:12Z","timestamp":1782885852000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/sc\/article\/16\/32\/14710-14723\/910651"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":49,"journal-issue":{"issue":"32","published-print":{"date-parts":[[2025,8,13]]}},"URL":"https:\/\/doi.org\/10.1039\/d5sc03944d","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D5SC03944D\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5SC03944D\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5SC03944D\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5SC03944D\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5SC03944D\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5SC03944D\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D5SC03944D\/v2\/review2","asserted-by":"object"}]},"ISSN":["2041-6520","2041-6539"],"issn-type":[{"value":"2041-6520","type":"print"},{"value":"2041-6539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}