{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T22:13:55Z","timestamp":1788214435048,"version":"build-2803163510"},"reference-count":31,"publisher":"Royal Society of Chemistry (RSC)","issue":"33","license":[{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"am","delay-in-days":562,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/100022831","name":"Sa\u011fl\u0131k Bilimleri \u00dcniversitesi","doi-asserted-by":"publisher","award":["2020\/046"],"award-info":[{"award-number":["2020\/046"]}],"id":[{"id":"10.13039\/100022831","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["J. Mater. Chem. B"],"abstract":"<jats:p>\n                    White spot lesions (WSLs) may develop in patients with inadequate oral hygiene during orthodontic treatment. This study aimed to develop a natural remineralization agent by creating artificial WSLs\n                    <jats:italic>in vitro<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1039\/d5tb00306g","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T10:00:36Z","timestamp":1752746436000},"page":"10206-10215","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Biomimetic management of orthodontic white spot lesions"],"prefix":"10.1039","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7371-1215","authenticated-orcid":false,"given":"Esra","family":"Tunal\u0131","sequence":"first","affiliation":[{"name":"Private Clinic, \u00c7anakkale, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u015eeniz","family":"Kara\u00e7ay","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Hamidiye Faculty of Dental Medicine Department of Orthodontics, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4553-2655","authenticated-orcid":false,"given":"Bu\u011fra","family":"\u00d6zen","sequence":"additional","affiliation":[{"name":"\u0130stanbul Health and Technology University, Faculty of Dentistry, Department of Pedodontics, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5918-3858","authenticated-orcid":false,"given":"Onder","family":"Albayrak","sequence":"additional","affiliation":[{"name":"Mersin University, Faculty of Engineering, Department of Mechanical Engineering, Mersin, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D5TB00306G\/cit1\/1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0002-9416(82)90032-X","volume":"81","author":"Gorelick","year":"1982","journal-title":"Am. J. Orthod."},{"key":"D5TB00306G\/cit2\/1","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1053\/j.sodo.2008.03.002","volume":"14","author":"Bishara","year":"2008","journal-title":"Semin. Orthod."},{"key":"D5TB00306G\/cit3\/1","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1159\/000331207","volume":"45","author":"Huang","year":"2011","journal-title":"Caries Res."},{"key":"D5TB00306G\/cit4\/1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/sca.21196","volume":"37","author":"Shafiei","year":"2015","journal-title":"Scanning"},{"key":"D5TB00306G\/cit5\/1","doi-asserted-by":"crossref","first-page":"6283","DOI":"10.1016\/j.actbio.2012.12.027","volume":"9","author":"Bleek","year":"2013","journal-title":"Acta Biomater."},{"key":"D5TB00306G\/cit6\/1","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1021\/bm000080z","volume":"2","author":"Aggeli","year":"2001","journal-title":"Biomacromolecules"},{"key":"D5TB00306G\/cit7\/1","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1177\/0022034517698419","volume":"96","author":"Kind","year":"2017","journal-title":"J. Dent. Res."},{"key":"D5TB00306G\/cit8\/1","first-page":"108","author":"Pepla","year":"2014","journal-title":"Ann. Stomatol."},{"key":"D5TB00306G\/cit9\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-44246-8","volume":"9","author":"Bohns","year":"2019","journal-title":"Sci. Rep."},{"key":"D5TB00306G\/cit10\/1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.colsurfb.2015.11.036","volume":"138","author":"\u015een","year":"2016","journal-title":"Colloids Surf., B"},{"key":"D5TB00306G\/cit11\/1","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.matchar.2016.01.006","volume":"113","author":"Albayrak","year":"2016","journal-title":"Mater. Charact."},{"key":"D5TB00306G\/cit12\/1","first-page":"749","volume":"31","author":"Albayrak","year":"2016","journal-title":"J. Fac. Eng. Archit. Gazi Univ."},{"key":"D5TB00306G\/cit13\/1","doi-asserted-by":"crossref","first-page":"e161","DOI":"10.4317\/jced.56295","volume":"12","author":"Kamal","year":"2020","journal-title":"J. Clin. Exp. Dent."},{"key":"D5TB00306G\/cit14\/1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.actbio.2004.09.008","volume":"1","author":"Kumta","year":"2005","journal-title":"Acta Biomater."},{"key":"D5TB00306G\/cit15\/1","first-page":"121","volume":"63","author":"Gehan","year":"2017","journal-title":"Eur. J. Dent."},{"key":"D5TB00306G\/cit16\/1","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1002\/jemt.23254","volume":"82","author":"\u00dcst\u00fcn","year":"2019","journal-title":"Microsc. Res. Tech."},{"key":"D5TB00306G\/cit17\/1","doi-asserted-by":"crossref","first-page":"5061","DOI":"10.1016\/j.biomaterials.2004.01.045","volume":"25","author":"Cross","year":"2004","journal-title":"Biomaterials"},{"key":"D5TB00306G\/cit18\/1","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.jdent.2010.01.001","volume":"38","author":"Lo","year":"2010","journal-title":"J. Dent."},{"key":"D5TB00306G\/cit19\/1","first-page":"10","volume":"19","author":"Babaji","year":"2019","journal-title":"Pesqui. Bras. Odontopediatr. Clin. Integr."},{"key":"D5TB00306G\/cit20\/1","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1177\/154405910708600507","volume":"86","author":"Kirkham","year":"2007","journal-title":"J. Dent. Res."},{"key":"D5TB00306G\/cit21\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/sj.bdj.2013.741","volume":"215","author":"Brunton","year":"2013","journal-title":"Br. Dent. J."},{"key":"D5TB00306G\/cit22\/1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.37506\/ijocd.v11i1.18813","volume":"11","author":"Gousalya","year":"2022","journal-title":"Indian J. Contemp. Dent."},{"key":"D5TB00306G\/cit23\/1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1055\/s-0041-1731931","volume":"16","author":"Puleio","year":"2022","journal-title":"Eur. J. Dent."},{"issue":"3","key":"D5TB00306G\/cit24\/1","doi-asserted-by":"crossref","first-page":"229","DOI":"10.4103\/JISPPD.JISPPD_242_16","volume":"35","author":"Kamath","year":"2017","journal-title":"J. Indian Soc. Pedod. Prev. Dent."},{"key":"D5TB00306G\/cit25\/1","first-page":"2006","volume":"85","author":"King","year":"2006","journal-title":"J. Dent. Res."},{"key":"D5TB00306G\/cit26\/1","doi-asserted-by":"crossref","first-page":"746383","DOI":"10.1155\/2009\/746383","author":"Roveri","year":"2009","journal-title":"J. Nanomater."},{"key":"D5TB00306G\/cit27\/1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ijpharm.2015.01.048","volume":"481","author":"Ferreira","year":"2015","journal-title":"Int. J. Pharm."},{"key":"D5TB00306G\/cit28\/1","doi-asserted-by":"crossref","first-page":"22743","DOI":"10.1016\/j.ceramint.2022.04.058","volume":"48","author":"Jodati","year":"2022","journal-title":"Ceram. Int."},{"key":"D5TB00306G\/cit29\/1","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1007\/s12011-020-02230-8","volume":"199","author":"Pazar\u00e7eviren","year":"2021","journal-title":"Biol. Trace Elem. Res."},{"key":"D5TB00306G\/cit30\/1","doi-asserted-by":"crossref","first-page":"205601","DOI":"10.1088\/0957-4484\/22\/20\/205601","volume":"22","author":"Lahiri","year":"2011","journal-title":"Nanotechnology"},{"key":"D5TB00306G\/cit31\/1","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.jdent.2010.01.001","volume":"38","author":"Lo","year":"2010","journal-title":"J. Dent."}],"container-title":["Journal of Materials Chemistry B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/TB\/D5TB00306G","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T18:23:50Z","timestamp":1782930230000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/tb\/article\/13\/33\/10206-10215\/916939"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":31,"journal-issue":{"issue":"33","published-print":{"date-parts":[[2025,8,20]]}},"URL":"https:\/\/doi.org\/10.1039\/d5tb00306g","relation":{},"ISSN":["2050-750X","2050-7518"],"issn-type":[{"value":"2050-750X","type":"print"},{"value":"2050-7518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}