{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T06:12:42Z","timestamp":1782972762387,"version":"3.54.5"},"reference-count":45,"publisher":"Royal Society of Chemistry (RSC)","issue":"36","license":[{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"am","delay-in-days":571,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2021R1C1C1009541"],"award-info":[{"award-number":["2021R1C1C1009541"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2021R1C1C1012378"],"award-info":[{"award-number":["2021R1C1C1012378"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2024-00508681"],"award-info":[{"award-number":["RS-2024-00508681"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018749","name":"Korea Brain Research Institute","doi-asserted-by":"publisher","award":["25-BR-01-03"],"award-info":[{"award-number":["25-BR-01-03"]}],"id":[{"id":"10.13039\/100018749","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018749","name":"Korea Brain Research Institute","doi-asserted-by":"publisher","award":["25-BR-07-01"],"award-info":[{"award-number":["25-BR-07-01"]}],"id":[{"id":"10.13039\/100018749","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018749","name":"Korea Brain Research Institute","doi-asserted-by":"publisher","award":["25-BR-08-01"],"award-info":[{"award-number":["25-BR-08-01"]}],"id":[{"id":"10.13039\/100018749","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004080","name":"Korea Drug Development Fund","doi-asserted-by":"publisher","award":["RS-2023-00283494"],"award-info":[{"award-number":["RS-2023-00283494"]}],"id":[{"id":"10.13039\/501100004080","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["J. Mater. Chem. B"],"abstract":"<jats:p>Lead compound KD01, an asymmetric pyridinium-based fluorescent probe, exhibits a large Stokes shift and selectively labels live human neural stem\/progenitor cells, offering a promising tool for stem cell imaging and neural lineage identification.<\/jats:p>","DOI":"10.1039\/d5tb00857c","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T23:40:54Z","timestamp":1753486854000},"page":"11224-11231","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Discovery of asymmetric pyridinium-based fluorescent probes with large Stokes shifts for live neural stem\/progenitor cells"],"prefix":"10.1039","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5415-3008","authenticated-orcid":false,"given":"Ye Ri","family":"Han","sequence":"first","affiliation":[{"name":"Department of Chemistry, Duksung Women's University, Seoul 01369, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4359-5782","authenticated-orcid":false,"given":"Dongwan","family":"Ko","sequence":"additional","affiliation":[{"name":"Neural Circuit Research Group, Korea Brain Research Institute, 61, Cheomdan-ro, Dong-gu, Daegu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1706-7169","authenticated-orcid":false,"given":"Yeongran","family":"Hwang","sequence":"additional","affiliation":[{"name":"Neural Circuit Research Group, Korea Brain Research Institute, 61, Cheomdan-ro, Dong-gu, Daegu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myeong A","family":"Choi","sequence":"additional","affiliation":[{"name":"New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, 80 Chembok-ro, Dong-gu, Daegu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do-Geun","family":"Kim","sequence":"additional","affiliation":[{"name":"Dementia Research Group, Korea Brain Research Institute, 61, Cheomdan-ro, Dong-gu, Daegu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Yeol","family":"Lee","sequence":"additional","affiliation":[{"name":"New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, 80 Chembok-ro, Dong-gu, Daegu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1207-7876","authenticated-orcid":false,"given":"Beomsue","family":"Kim","sequence":"additional","affiliation":[{"name":"Neural Circuit Research Group, Korea Brain Research Institute, 61, Cheomdan-ro, Dong-gu, Daegu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2025]]},"reference":[{"key":"D5TB00857C\/cit1\/1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.2174\/2352633501501010007","volume":"1","author":"Moumaris","year":"2015","journal-title":"Open Biol. Sci. J."},{"key":"D5TB00857C\/cit2\/1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0165-0270(00)00340-X","volume":"104","author":"Buckman","year":"2001","journal-title":"J. Neurosci. Methods"},{"key":"D5TB00857C\/cit3\/1","doi-asserted-by":"crossref","first-page":"2713","DOI":"10.1016\/j.biomaterials.2004.07.050","volume":"26","author":"Win","year":"2005","journal-title":"Biomaterials"},{"key":"D5TB00857C\/cit4\/1","doi-asserted-by":"crossref","first-page":"24.22.21","DOI":"10.1002\/0471143030.cb2402s35","volume":"35","author":"Listenberger","year":"2007","journal-title":"Curr. Protoc. Cell Biol."},{"key":"D5TB00857C\/cit5\/1","first-page":"e1912","volume":"6","author":"Qiu","year":"2016","journal-title":"Bio-protoc."},{"key":"D5TB00857C\/cit6\/1","doi-asserted-by":"crossref","first-page":"8056","DOI":"10.1002\/ange.201903058","volume":"131","author":"Kim","year":"2019","journal-title":"Angew. Chem."},{"key":"D5TB00857C\/cit7\/1","doi-asserted-by":"crossref","first-page":"2442","DOI":"10.1002\/anie.201408614","volume":"54","author":"Er","year":"2015","journal-title":"Angew. Chem., Int. Ed."},{"key":"D5TB00857C\/cit8\/1","doi-asserted-by":"crossref","first-page":"e202307641","DOI":"10.1002\/anie.202307641","volume":"62","author":"Si","year":"2023","journal-title":"Angew. Chem., Int. Ed."},{"key":"D5TB00857C\/cit9\/1","doi-asserted-by":"crossref","first-page":"7106","DOI":"10.1021\/acs.chemrev.3c00776","volume":"124","author":"Wang","year":"2024","journal-title":"Chem. Rev."},{"key":"D5TB00857C\/cit10\/1","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1039\/D3CC04895K","volume":"60","author":"Munan","year":"2024","journal-title":"Chem. Commun."},{"key":"D5TB00857C\/cit11\/1","doi-asserted-by":"crossref","first-page":"6044","DOI":"10.1039\/D5TB00286A","volume":"13","author":"Han","year":"2025","journal-title":"J. Mater. Chem. B"},{"key":"D5TB00857C\/cit12\/1","doi-asserted-by":"crossref","first-page":"10429","DOI":"10.1021\/cr5001157","volume":"114","author":"Machado","year":"2014","journal-title":"Chem. Rev."},{"key":"D5TB00857C\/cit13\/1","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1021\/acs.jnatprod.1c01190","volume":"85","author":"Lee","year":"2022","journal-title":"J. Nat. Prod."},{"key":"D5TB00857C\/cit14\/1","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1021\/cr980032t","volume":"99","author":"Welton","year":"1999","journal-title":"Chem. Rev."},{"key":"D5TB00857C\/cit15\/1","doi-asserted-by":"crossref","first-page":"6540","DOI":"10.1021\/acsapm.4c00805","volume":"6","author":"Hazra","year":"2024","journal-title":"ACS Appl. Polym. Mater."},{"key":"D5TB00857C\/cit16\/1","doi-asserted-by":"crossref","first-page":"23362","DOI":"10.1021\/acsami.8b04869","volume":"10","author":"Wu","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D5TB00857C\/cit17\/1","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1021\/acs.analchem.5b04777","volume":"88","author":"Yao","year":"2016","journal-title":"Anal. Chem."},{"key":"D5TB00857C\/cit18\/1","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1039\/C7QO00836H","volume":"5","author":"Sowmiah","year":"2018","journal-title":"Org. Chem. Front."},{"key":"D5TB00857C\/cit19\/1","doi-asserted-by":"crossref","first-page":"8184","DOI":"10.1021\/ja0203317","volume":"124","author":"Yamada","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"D5TB00857C\/cit20\/1","doi-asserted-by":"crossref","first-page":"5219","DOI":"10.1021\/jo049724+","volume":"69","author":"Kuethe","year":"2004","journal-title":"J. Org. Chem."},{"key":"D5TB00857C\/cit21\/1","doi-asserted-by":"crossref","first-page":"4719","DOI":"10.1021\/ja00090a019","volume":"116","author":"Comins","year":"1994","journal-title":"J. Am. Chem. Soc."},{"key":"D5TB00857C\/cit22\/1","doi-asserted-by":"crossref","first-page":"6360","DOI":"10.1021\/ja0348647","volume":"125","author":"Legault","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"D5TB00857C\/cit23\/1","doi-asserted-by":"crossref","first-page":"8966","DOI":"10.1021\/ja0525298","volume":"127","author":"Legault","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"D5TB00857C\/cit24\/1","doi-asserted-by":"crossref","first-page":"9339","DOI":"10.1002\/anie.200904981","volume":"48","author":"Fernandez-Ibanez","year":"2009","journal-title":"Angew. Chem., Int. Ed."},{"key":"D5TB00857C\/cit25\/1","doi-asserted-by":"crossref","first-page":"2642","DOI":"10.1021\/cr200251d","volume":"112","author":"Bull","year":"2012","journal-title":"Chem. Rev."},{"key":"D5TB00857C\/cit26\/1","doi-asserted-by":"crossref","first-page":"13225","DOI":"10.1021\/acscatal.2c04417","volume":"12","author":"Kim","year":"2022","journal-title":"ACS Catal."},{"key":"D5TB00857C\/cit27\/1","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1021\/acs.accounts.2c00530","volume":"55","author":"Kim","year":"2022","journal-title":"Acc. Chem. Res."},{"key":"D5TB00857C\/cit28\/1","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1021\/acs.orglett.5b00028","volume":"17","author":"Luo","year":"2015","journal-title":"Org. Lett."},{"key":"D5TB00857C\/cit29\/1","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1021\/acs.orglett.7b03654","volume":"20","author":"Han","year":"2018","journal-title":"Org. Lett."},{"key":"D5TB00857C\/cit30\/1","doi-asserted-by":"crossref","first-page":"14181","DOI":"10.1002\/chem.201302290","volume":"19","author":"Luo","year":"2013","journal-title":"Chemistry"},{"key":"D5TB00857C\/cit31\/1","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.3233\/JAD-2010-091363","volume":"20","author":"Agholme","year":"2010","journal-title":"J. Alzheimers Dis."},{"key":"D5TB00857C\/cit32\/1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/978-1-62703-640-5_2","volume":"1078","author":"Kovalevich","year":"2013","journal-title":"Methods Mol. Biol."},{"key":"D5TB00857C\/cit33\/1","first-page":"53193","author":"Shipley","year":"2016","journal-title":"J. Visualized Exp."},{"key":"D5TB00857C\/cit34\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41597-018-0005-2","volume":"6","author":"Song","year":"2019","journal-title":"Sci. Data"},{"key":"D5TB00857C\/cit35\/1","doi-asserted-by":"crossref","first-page":"10214","DOI":"10.1073\/pnas.1200817109","volume":"109","author":"Yun","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D5TB00857C\/cit36\/1","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1021\/acs.chemrev.3c00573","volume":"124","author":"Ma","year":"2024","journal-title":"Chem. Rev."},{"key":"D5TB00857C\/cit37\/1","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.3892\/ijmm.2016.2751","volume":"38","author":"Jiang","year":"2016","journal-title":"Int. J. Mol. Med."},{"key":"D5TB00857C\/cit38\/1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/neu.480270104","volume":"27","author":"Memberg","year":"1995","journal-title":"J. Neurobiol."},{"key":"D5TB00857C\/cit39\/1","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3389\/fnana.2018.00104","volume":"12","author":"Martinez-Cerdeno","year":"2018","journal-title":"Front. Neuroanat."},{"key":"D5TB00857C\/cit40\/1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0166-2236(03)00031-6","volume":"26","author":"Seaberg","year":"2003","journal-title":"Trends Neurosci."},{"key":"D5TB00857C\/cit41\/1","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/nrn4021","volume":"16","author":"Homem","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"D5TB00857C\/cit42\/1","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/s42003-023-04893-0","volume":"6","author":"Aceves","year":"2023","journal-title":"Commun. Biol."},{"key":"D5TB00857C\/cit43\/1","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/s41583-020-0314-2","volume":"21","author":"Fischer","year":"2020","journal-title":"Nat. Rev. Neurosci."},{"key":"D5TB00857C\/cit44\/1","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3389\/fncel.2014.00291","volume":"8","author":"Hermann","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"D5TB00857C\/cit45\/1","doi-asserted-by":"crossref","first-page":"794692","DOI":"10.3389\/fncel.2021.794692","volume":"15","author":"Suzuki","year":"2021","journal-title":"Front. Cell. Neurosci."}],"container-title":["Journal of Materials Chemistry B"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2025\/TB\/D5TB00857C","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:51:22Z","timestamp":1782967882000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/tb\/article\/13\/36\/11224-11231\/917106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":45,"journal-issue":{"issue":"36","published-print":{"date-parts":[[2025,9,17]]}},"URL":"https:\/\/doi.org\/10.1039\/d5tb00857c","relation":{},"ISSN":["2050-750X","2050-7518"],"issn-type":[{"value":"2050-750X","type":"print"},{"value":"2050-7518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}