{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T02:35:59Z","timestamp":1784342159171,"version":"3.55.0"},"reference-count":27,"publisher":"Royal Society of Chemistry (RSC)","issue":"9","license":[{"start":{"date-parts":[[2027,3,18]],"date-time":"2027-03-18T00:00:00Z","timestamp":1805328000000},"content-version":"am","delay-in-days":441,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22276103"],"award-info":[{"award-number":["22276103"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Analyst"],"abstract":"<jats:p>An innovative combined qualitative and quantitative method for detecting the content of tyloxapol in tobramycin eye drops.<\/jats:p>","DOI":"10.1039\/d6an00042h","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T10:41:09Z","timestamp":1773830469000},"page":"2694-2703","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Simultaneous qualitative and quantitative analysis of tyloxapol in tobramycin eye drops by LC-Q-TOF and HPLC-ELSD"],"prefix":"10.1039","volume":"151","author":[{"given":"Shengjun","family":"Che","sequence":"first","affiliation":[{"name":"Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, and College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Liang","sequence":"additional","affiliation":[{"name":"Pharmaceutical Division, Link-Transform Pharmaceutical Technology (Shandong) Co., Ltd, Qingdao 370212, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Yan","sequence":"additional","affiliation":[{"name":"Pharmaceutical Division, Link-Transform Pharmaceutical Technology (Shandong) Co., Ltd, Qingdao 370212, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2251-3208","authenticated-orcid":false,"given":"Xiaoru","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, and College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenfeng","family":"Zheng","sequence":"additional","affiliation":[{"name":"Pharmaceutical Division, Link-Transform Pharmaceutical Technology (Shandong) Co., Ltd, Qingdao 370212, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"issue":"4","key":"D6AN00042H\/cit1\/1","doi-asserted-by":"publisher","first-page":"597","DOI":"10.2174\/1871520617666171121124610","volume":"18","author":"Maiti","year":"2018","journal-title":"Anti Cancer Agents Med. Chem."},{"key":"D6AN00042H\/cit2\/1","doi-asserted-by":"publisher","first-page":"114496","DOI":"10.1016\/j.jpba.2021.114496","volume":"209","author":"\u010capkov\u00e1","year":"2022","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"1","key":"D6AN00042H\/cit3\/1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/10837450.2024.2441181","volume":"30","author":"Comoglu","year":"2025","journal-title":"Pharm. Dev. Technol."},{"issue":"21","key":"D6AN00042H\/cit4\/1","doi-asserted-by":"publisher","first-page":"8224","DOI":"10.3390\/ijms21218224","volume":"21","author":"Patel","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"D6AN00042H\/cit5\/1","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.taap.2008.06.019","volume":"232","author":"Kristl","year":"2008","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"D6AN00042H\/cit6\/1","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.jcis.2016.01.037","volume":"468","author":"Shen","year":"2016","journal-title":"J. Colloid Interface Sci."},{"issue":"1","key":"D6AN00042H\/cit7\/1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000444589","volume":"98","author":"Beubler","year":"2016","journal-title":"Pharmacology"},{"key":"D6AN00042H\/cit8\/1","doi-asserted-by":"publisher","first-page":"143739","DOI":"10.1016\/j.chemosphere.2024.143739","volume":"368","author":"Bading","year":"2024","journal-title":"Chemosphere"},{"issue":"20","key":"D6AN00042H\/cit9\/1","doi-asserted-by":"publisher","first-page":"3386","DOI":"10.3390\/ma12203386","volume":"12","author":"Wasilewska","year":"2019","journal-title":"Materials"},{"key":"D6AN00042H\/cit10\/1","doi-asserted-by":"publisher","first-page":"115946","DOI":"10.1016\/j.desal.2022.115946","volume":"539","author":"Madden","year":"2022","journal-title":"Desalination"},{"issue":"3","key":"D6AN00042H\/cit11\/1","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1007\/s11094-023-02899-w","volume":"57","author":"Bakhrushina","year":"2023","journal-title":"Pharm. Chem. J."},{"issue":"13","key":"D6AN00042H\/cit12\/1","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1002\/pol.20200027","volume":"58","author":"Moln\u00e1r","year":"2020","journal-title":"J. Polym. Sci."},{"issue":"49","key":"D6AN00042H\/cit13\/1","doi-asserted-by":"publisher","first-page":"22416","DOI":"10.1021\/jacs.2c10036","volume":"144","author":"Garcia","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"D6AN00042H\/cit14\/1","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.aca.2020.09.062","volume":"1140","author":"Svejdal","year":"2020","journal-title":"Anal. Chim. Acta"},{"issue":"35","key":"D6AN00042H\/cit15\/1","doi-asserted-by":"publisher","first-page":"19383","DOI":"10.1002\/anie.202106729","volume":"60","author":"Whitfield","year":"2021","journal-title":"Angew. Chem., Int. Ed."},{"issue":"3","key":"D6AN00042H\/cit16\/1","doi-asserted-by":"publisher","first-page":"e70028","DOI":"10.1002\/chir.70028","volume":"37","author":"Gollapudi","year":"2025","journal-title":"Chirality"},{"issue":"2","key":"D6AN00042H\/cit17\/1","doi-asserted-by":"publisher","first-page":"100488","DOI":"10.1016\/j.cjac.2024.100488","volume":"53","author":"Haizhen","year":"2025","journal-title":"Chin. J. Anal. Chem."},{"issue":"9","key":"D6AN00042H\/cit18\/1","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1039\/D5AN00075K","volume":"150","author":"Wu","year":"2025","journal-title":"Analyst"},{"issue":"1","key":"D6AN00042H\/cit19\/1","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1016\/j.jfda.2018.06.007","volume":"27","author":"Gedawy","year":"2019","journal-title":"J. Food Drug Anal."},{"key":"D6AN00042H\/cit20\/1","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1039\/D5AN01086A","volume":"151","author":"Gaggero","year":"2026","journal-title":"Analyst"},{"key":"D6AN00042H\/cit21\/1","doi-asserted-by":"publisher","first-page":"100592","DOI":"10.1016\/j.cjac.2025.100592","author":"Bolin","year":"2025","journal-title":"Chin. J. Anal. Chem."},{"issue":"1","key":"D6AN00042H\/cit22\/1","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1021\/acs.chemrev.3c00440","volume":"124","author":"Mundil","year":"2023","journal-title":"Chem. Rev."},{"key":"D6AN00042H\/cit23\/1","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.talanta.2018.10.005","volume":"194","author":"Wu","year":"2019","journal-title":"Talanta"},{"key":"D6AN00042H\/cit24\/1","doi-asserted-by":"publisher","first-page":"342258","DOI":"10.1016\/j.aca.2024.342258","volume":"1292","author":"Sun","year":"2024","journal-title":"Anal. Chim. Acta"},{"issue":"20","key":"D6AN00042H\/cit25\/1","doi-asserted-by":"publisher","first-page":"15615","DOI":"10.1021\/acs.energyfuels.3c02922","volume":"37","author":"Jia","year":"2023","journal-title":"Energy Fuels"},{"key":"D6AN00042H\/cit26\/1","doi-asserted-by":"publisher","first-page":"115011","DOI":"10.1016\/j.jpba.2022.115011","volume":"220","author":"Mousli","year":"2022","journal-title":"J. Pharm. Biomed. Anal."},{"key":"D6AN00042H\/cit27\/1","doi-asserted-by":"publisher","first-page":"110666","DOI":"10.1016\/j.microc.2024.110666","volume":"201","author":"Luo","year":"2024","journal-title":"Microchem. J."}],"container-title":["The Analyst"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2026\/AN\/D6AN00042H","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:23:49Z","timestamp":1782969829000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/an\/article\/151\/9\/2694-2703\/1244501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,5,5]]}},"URL":"https:\/\/doi.org\/10.1039\/d6an00042h","relation":{},"ISSN":["0003-2654","1364-5528"],"issn-type":[{"value":"0003-2654","type":"print"},{"value":"1364-5528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}