{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:47:20Z","timestamp":1791910040384,"version":"4.3.4"},"reference-count":52,"publisher":"Royal Society of Chemistry (RSC)","issue":"20","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"vor","delay-in-days":266,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01-GM150948"],"award-info":[{"award-number":["R01-GM150948"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100023581","name":"National Science Foundation Graduate Research Fellowship Program","doi-asserted-by":"publisher","award":["DGE-2241144"],"award-info":[{"award-number":["DGE-2241144"]}],"id":[{"id":"10.13039\/100023581","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Analyst"],"abstract":"<jats:p>\n                    Machine vision camera method for label-free measurement of OD\n                    <jats:sub>600<\/jats:sub>\n                    of microbes growing in flowing nanoliter droplets at 10 samples per s is presented.\n                  <\/jats:p>","DOI":"10.1039\/d6an00623j","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:33:27Z","timestamp":1790242407000},"page":"6036-6046","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Machine vision-enabled OD\n                    <sub>600<\/sub>\n                    measurement and mass spectrometric determination of metabolites of microbial cell-containing microfluidic droplets in real-time"],"prefix":"10.1039","volume":"151","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3800-3434","authenticated-orcid":false,"given":"G. Thomas","family":"Knecht","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6081-8344","authenticated-orcid":false,"given":"Maxwell J.","family":"Unger","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA"},{"name":"Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8290-0077","authenticated-orcid":false,"given":"Alison R. H.","family":"Narayan","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA"},{"name":"Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA"},{"name":"Program in Chemical Biology, University of Michigan, Ann Arbor, Michigan 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2447-7471","authenticated-orcid":false,"given":"Robert T.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6AN00623J\/cit1\/1","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1039\/b902504a","volume":"9","author":"Baret","year":"2009","journal-title":"Lab Chip"},{"key":"D6AN00623J\/cit2\/1","doi-asserted-by":"crossref","first-page":"15716","DOI":"10.1021\/acs.analchem.3c03080","volume":"95","author":"Payne","year":"2023","journal-title":"Anal. Chem."},{"key":"D6AN00623J\/cit3\/1","doi-asserted-by":"crossref","first-page":"E7383","DOI":"10.1073\/pnas.1606927113","volume":"113","author":"Gielen","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6AN00623J\/cit4\/1","doi-asserted-by":"crossref","first-page":"3707","DOI":"10.1039\/c3lc50572c","volume":"13","author":"Zang","year":"2013","journal-title":"Lab Chip"},{"key":"D6AN00623J\/cit5\/1","doi-asserted-by":"crossref","first-page":"13087","DOI":"10.1038\/s41598-018-31263-2","volume":"8","author":"Mahler","year":"2018","journal-title":"Sci. Rep."},{"key":"D6AN00623J\/cit6\/1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1080\/21655979.2016.1156824","volume":"7","author":"Keays","year":"2016","journal-title":"Bioengineered"},{"key":"D6AN00623J\/cit7\/1","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1039\/C6LC00180G","volume":"16","author":"Liu","year":"2016","journal-title":"Lab Chip"},{"key":"D6AN00623J\/cit8\/1","doi-asserted-by":"crossref","first-page":"024118","DOI":"10.1063\/1.4918754","volume":"9","author":"Yu","year":"2015","journal-title":"Biomicrofluidics"},{"key":"D6AN00623J\/cit9\/1","doi-asserted-by":"crossref","first-page":"107670","DOI":"10.1016\/j.celrep.2020.107670","volume":"31","author":"Tomasi","year":"2020","journal-title":"Cell Rep."},{"key":"D6AN00623J\/cit10\/1","doi-asserted-by":"crossref","first-page":"7061","DOI":"10.1021\/acs.chemrev.1c00666","volume":"122","author":"Sart","year":"2022","journal-title":"Chem. Rev."},{"key":"D6AN00623J\/cit11\/1","doi-asserted-by":"crossref","first-page":"1900188","DOI":"10.1002\/adbi.201900188","volume":"4","author":"Matula","year":"2020","journal-title":"Adv. Biosyst."},{"key":"D6AN00623J\/cit12\/1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1146\/annurev.mi.03.100149.002103","volume":"3","author":"Monod","year":"1949","journal-title":"Annu. Rev. Microbiol."},{"key":"D6AN00623J\/cit13\/1","first-page":"172","volume":"5","author":"Rosano","year":"2014","journal-title":"Front. Microbiol."},{"key":"D6AN00623J\/cit14\/1","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.3390\/molecules28031418","volume":"28","author":"Luo","year":"2023","journal-title":"Molecules"},{"key":"D6AN00623J\/cit15\/1","doi-asserted-by":"crossref","first-page":"e0276040","DOI":"10.1371\/journal.pone.0276040","volume":"17","author":"Mira","year":"2022","journal-title":"PLoS One"},{"key":"D6AN00623J\/cit16\/1","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/s42003-020-01127-5","volume":"3","author":"Beal","year":"2020","journal-title":"Commun. Biol."},{"key":"D6AN00623J\/cit17\/1","doi-asserted-by":"crossref","first-page":"38828","DOI":"10.1038\/srep38828","volume":"6","author":"Stevenson","year":"2016","journal-title":"Sci. Rep."},{"key":"D6AN00623J\/cit18\/1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.3390\/mi9050251","volume":"9","author":"Sklodowska","year":"2018","journal-title":"Micromachines"},{"key":"D6AN00623J\/cit19\/1","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1039\/D0LC00830C","volume":"21","author":"Zurek","year":"2021","journal-title":"Lab Chip"},{"key":"D6AN00623J\/cit20\/1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.3390\/bios12010034","volume":"12","author":"Rauf","year":"2022","journal-title":"Biosensors"},{"key":"D6AN00623J\/cit21\/1","doi-asserted-by":"crossref","first-page":"12039","DOI":"10.1021\/acsomega.2c00248","volume":"7","author":"Geersens","year":"2022","journal-title":"ACS Omega"},{"key":"D6AN00623J\/cit22\/1","doi-asserted-by":"crossref","first-page":"026003","DOI":"10.1088\/1478-3975\/ac4c9b","volume":"19","author":"Taylor","year":"2022","journal-title":"Phys. Biol."},{"key":"D6AN00623J\/cit23\/1","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1038\/s41378-026-01349-3","volume":"12","author":"Guo","year":"2026","journal-title":"Microsyst. Nanoeng."},{"key":"D6AN00623J\/cit24\/1","doi-asserted-by":"crossref","first-page":"2500236","DOI":"10.1002\/smtd.202500236","volume":"9","author":"Aubermann","year":"2025","journal-title":"Small Methods"},{"key":"D6AN00623J\/cit25\/1","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.foodhyd.2017.03.035","volume":"70","author":"Amine","year":"2017","journal-title":"Food Hydrocolloids"},{"key":"D6AN00623J\/cit26\/1","doi-asserted-by":"crossref","first-page":"3309","DOI":"10.1039\/C8AN00456K","volume":"143","author":"Cui","year":"2018","journal-title":"Analyst"},{"key":"D6AN00623J\/cit27\/1","doi-asserted-by":"crossref","first-page":"101871","DOI":"10.1039\/C5RA20118G","volume":"5","author":"Mahler","year":"2015","journal-title":"RSC Adv."},{"key":"D6AN00623J\/cit28\/1","doi-asserted-by":"crossref","first-page":"2500520","DOI":"10.1002\/smll.202500520","volume":"21","author":"Liu","year":"2025","journal-title":"Small"},{"key":"D6AN00623J\/cit29\/1","doi-asserted-by":"crossref","first-page":"4668","DOI":"10.1021\/acsami.1c19276","volume":"14","author":"Siemenn","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D6AN00623J\/cit30\/1","doi-asserted-by":"crossref","first-page":"122136","DOI":"10.1016\/j.talanta.2021.122136","volume":"226","author":"Wang","year":"2021","journal-title":"Talanta"},{"key":"D6AN00623J\/cit31\/1","doi-asserted-by":"crossref","first-page":"014302","DOI":"10.1063\/1.3274673","volume":"81","author":"Shin","year":"2010","journal-title":"Rev. Sci. Instrum."},{"key":"D6AN00623J\/cit32\/1","doi-asserted-by":"crossref","first-page":"2413146","DOI":"10.1002\/advs.202413146","volume":"12","author":"Wang","year":"2025","journal-title":"Adv. Sci."},{"key":"D6AN00623J\/cit33\/1","doi-asserted-by":"crossref","first-page":"6558","DOI":"10.1021\/ac901172a","volume":"81","author":"Pei","year":"2009","journal-title":"Anal. Chem."},{"key":"D6AN00623J\/cit34\/1","doi-asserted-by":"crossref","first-page":"3665","DOI":"10.1002\/anie.200806103","volume":"48","author":"Fidalgo","year":"2009","journal-title":"Angew. Chem., Int. Ed."},{"key":"D6AN00623J\/cit35\/1","doi-asserted-by":"crossref","first-page":"6645","DOI":"10.1021\/acs.analchem.9b00571","volume":"91","author":"Steyer","year":"2019","journal-title":"Anal. Chem."},{"key":"D6AN00623J\/cit36\/1","doi-asserted-by":"crossref","first-page":"12605","DOI":"10.1021\/acs.analchem.0c02632","volume":"92","author":"Kempa","year":"2020","journal-title":"Anal. Chem."},{"key":"D6AN00623J\/cit37\/1","doi-asserted-by":"crossref","first-page":"8361","DOI":"10.1021\/ac101902c","volume":"82","author":"Zhu","year":"2010","journal-title":"Anal. Chem."},{"key":"D6AN00623J\/cit38\/1","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1021\/acsomega.7b01973","volume":"3","author":"Diefenbach","year":"2018","journal-title":"ACS Omega"},{"key":"D6AN00623J\/cit39\/1","doi-asserted-by":"crossref","first-page":"kuad025","DOI":"10.1093\/jimb\/kuad025","volume":"50","author":"Abbate","year":"2023","journal-title":"J. Ind. Microbiol. Biot."},{"key":"D6AN00623J\/cit40\/1","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1021\/cr980002q","volume":"99","author":"Xia","year":"1999","journal-title":"Chem. Rev."},{"key":"D6AN00623J\/cit41\/1","doi-asserted-by":"crossref","first-page":"024104","DOI":"10.1063\/1.2164911","volume":"88","author":"Ahn","year":"2006","journal-title":"Appl. Phys. Lett."},{"key":"D6AN00623J\/cit42\/1","doi-asserted-by":"crossref","first-page":"3439","DOI":"10.1039\/C5LC00614G","volume":"15","author":"Collins","year":"2015","journal-title":"Lab Chip"},{"key":"D6AN00623J\/cit43\/1","doi-asserted-by":"crossref","first-page":"4470","DOI":"10.1002\/anie.201913203","volume":"59","author":"Holland-Moritz","year":"2020","journal-title":"Angew. Chem., Int. Ed."},{"key":"D6AN00623J\/cit44\/1","doi-asserted-by":"crossref","first-page":"26607","DOI":"10.1021\/acs.analchem.5c05032","volume":"97","author":"Mavrakis","year":"2025","journal-title":"Anal. Chem."},{"key":"D6AN00623J\/cit45\/1","doi-asserted-by":"crossref","first-page":"6815","DOI":"10.1021\/acs.analchem.9b01017","volume":"91","author":"Qin","year":"2019","journal-title":"Anal. Chem."},{"key":"D6AN00623J\/cit46\/1","doi-asserted-by":"crossref","first-page":"8728","DOI":"10.1073\/pnas.1704020114","volume":"114","author":"Cole","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6AN00623J\/cit47\/1","doi-asserted-by":"crossref","first-page":"e00697","DOI":"10.1128\/JB.00697-18","volume":"201","author":"Bertrand","year":"2019","journal-title":"J. Bacteriol."},{"key":"D6AN00623J\/cit48\/1","doi-asserted-by":"crossref","first-page":"8289","DOI":"10.1016\/j.chroma.2009.05.036","volume":"1216","author":"Mohamed","year":"2009","journal-title":"J. Chromatogr. A"},{"key":"D6AN00623J\/cit49\/1","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/pros.2990250505","volume":"25","author":"Rinker-Schaeffer","year":"1994","journal-title":"Prostate"},{"key":"D6AN00623J\/cit50\/1","first-page":"1153","volume":"71","author":"Simerville","year":"2005","journal-title":"Am. Fam. Physician"},{"key":"D6AN00623J\/cit51\/1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1046\/j.1365-2141.1997.72653.x","volume":"97","author":"Rawstron","year":"1997","journal-title":"Br. J. Haematol."},{"key":"D6AN00623J\/cit52\/1","first-page":"1103","volume":"68","author":"Seehusen","year":"2003","journal-title":"Am. Fam. Physician"}],"container-title":["The Analyst"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/AN\/article-pdf\/doi\/10.1039\/D6AN00623J\/0\/D6AN00623J.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:56:13Z","timestamp":1791906973000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/AN\/article-lookup\/doi\/10.1039\/D6AN00623J"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":52,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2026,10,13]]}},"URL":"https:\/\/doi.org\/10.1039\/d6an00623j","relation":{},"ISSN":["0003-2654","1364-5528"],"issn-type":[{"value":"0003-2654","type":"print"},{"value":"1364-5528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}