{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:05:01Z","timestamp":1790687101681,"version":"4.1.0"},"reference-count":35,"publisher":"Royal Society of Chemistry (RSC)","issue":"19","license":[{"start":{"date-parts":[[2027,8,18]],"date-time":"2027-08-18T00:00:00Z","timestamp":1818547200000},"content-version":"am","delay-in-days":594,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100002642","name":"Korea University","doi-asserted-by":"publisher","award":["K2406231"],"award-info":[{"award-number":["K2406231"]}],"id":[{"id":"10.13039\/501100002642","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["RS-2025-20122968"],"award-info":[{"award-number":["RS-2025-20122968"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Analyst"],"abstract":"<jats:p>\n                    An HRP\/TMB-amplified signal-on electrochemical aptasensor using the J3\/JH4 cognate pair enables H5N2 detection in a buffer and a processed duck fecal matrix, achieving LODs of 2.00 \u00d7 10\n                    <jats:sup>4<\/jats:sup>\n                    and 2.76 \u00d7 10\n                    <jats:sup>4<\/jats:sup>\n                    EID\n                    <jats:sub>50<\/jats:sub>\n                    per mL.\n                  <\/jats:p>","DOI":"10.1039\/d6an00800c","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T17:23:19Z","timestamp":1787073799000},"page":"5830-5838","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An interface-engineered signal-on electrochemical aptasensor for H5N2 avian influenza virus detection"],"prefix":"10.1039","volume":"151","author":[{"given":"Thi Thanh-Thao","family":"Dang","sequence":"first","affiliation":[{"name":"Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-gu, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Hoon","family":"Kim","sequence":"additional","affiliation":[{"name":"University of North Carolina \u2013 Chapel Hill, Department of Applied Physical Sciences, 1112 Murray Hall, CB#3050, Chapel Hill, NC 27599-2100, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bang Hyun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Electrical & Computer Engineering, North Carolina State University, 890 Oval Dr., Raleigh, NC, 27695, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jungbae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biological Engineering, Korea University, Anam-dong, Seongbuk-gu, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Seon","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, Konkuk University, Seoul, 05029, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0848-5394","authenticated-orcid":false,"given":"Man Bock","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-gu, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6AN00800C\/cit1\/1","first-page":"6497","volume":"19","author":"Adlhoch","year":"2021","journal-title":"EFSA J."},{"key":"D6AN00800C\/cit2\/1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.vaccine.2008.07.039","volume":"26","author":"Bouvier","year":"2008","journal-title":"Vaccine"},{"key":"D6AN00800C\/cit3\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-59745-279-3","volume-title":"Avian influenza virus","volume":"436","author":"Spackman","year":"2008","unstructured":"E.Spackman , in  Avian influenza virus , ed.  E. Spackman ,  Humana Totowa ,  NJ , 1st edn,  2008 , vol.  436 , pp.  1\u20136"},{"key":"D6AN00800C\/cit4\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/v8040096","volume":"8","author":"Vemula","year":"2016","journal-title":"Viruses"},{"key":"D6AN00800C\/cit5\/1","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.cimid.2008.01.004","volume":"32","author":"Lupiani","year":"2009","journal-title":"Comp. Immunol., Microbiol. Infect. Dis."},{"key":"D6AN00800C\/cit6\/1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.bios.2016.06.064","volume":"86","author":"Nguyen","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"D6AN00800C\/cit7\/1","doi-asserted-by":"crossref","first-page":"5677","DOI":"10.1128\/JVI.00139-14","volume":"88","author":"Lee","year":"2014","journal-title":"J. Virol."},{"key":"D6AN00800C\/cit8\/1","first-page":"1","author":"Hall","year":"2021","journal-title":"Influenza Other Respir. Viruses"},{"key":"D6AN00800C\/cit9\/1","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.cll.2014.02.009","volume":"34","author":"Peaper","year":"2014","journal-title":"Clin. Lab. Med."},{"key":"D6AN00800C\/cit10\/1","first-page":"1","volume":"12","author":"Verhagen","year":"2017","journal-title":"PLoS One"},{"key":"D6AN00800C\/cit11\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/bios8040094","volume":"8","author":"Dziabowska","year":"2018","journal-title":"Biosensors"},{"key":"D6AN00800C\/cit12\/1","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.1128\/JCM.42.6.2796-2798.2004","volume":"42","author":"Pachucki","year":"2004","journal-title":"J. Clin. Microbiol."},{"key":"D6AN00800C\/cit13\/1","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s13206-020-4401-2","volume":"14","author":"Kim","year":"2020","journal-title":"BioChip J."},{"key":"D6AN00800C\/cit14\/1","doi-asserted-by":"crossref","first-page":"111476","DOI":"10.1016\/j.bios.2019.111476","volume":"141","author":"Zhang","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"D6AN00800C\/cit15\/1","doi-asserted-by":"crossref","first-page":"16683","DOI":"10.1021\/acsomega.9b02788","volume":"4","author":"Ch\u00e1vez Ramos","year":"2019","journal-title":"ACS Omega"},{"key":"D6AN00800C\/cit16\/1","first-page":"36","volume":"2","author":"Azimzadeh","year":"2017","journal-title":"Nanomed. Res. J."},{"key":"D6AN00800C\/cit17\/1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.copbio.2016.11.020","volume":"45","author":"Nguyen","year":"2017","journal-title":"Curr. Opin. Biotechnol."},{"key":"D6AN00800C\/cit18\/1","doi-asserted-by":"crossref","first-page":"037523","DOI":"10.1149\/2.0232003JES","volume":"167","author":"Ozer","year":"2020","journal-title":"J. Electrochem. Soc."},{"key":"D6AN00800C\/cit19\/1","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1002\/asia.202100242","volume":"16","author":"Han","year":"2021","journal-title":"Chem. \u2013 Asian J."},{"key":"D6AN00800C\/cit20\/1","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1038\/346818a0","volume":"346","author":"Ellington","year":"1990","journal-title":"Nature"},{"key":"D6AN00800C\/cit21\/1","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.4014\/jmb.1708.08015","volume":"27","author":"Lee","year":"2017","journal-title":"J. Microbiol. Biotechnol."},{"key":"D6AN00800C\/cit22\/1","doi-asserted-by":"crossref","first-page":"9877","DOI":"10.1007\/s00253-020-10940-1","volume":"104","author":"Yi","year":"2020","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"D6AN00800C\/cit23\/1","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1351\/PAC-REP-09-08-16","volume":"82","author":"Labuda","year":"2010","journal-title":"Pure Appl. Chem."},{"key":"D6AN00800C\/cit24\/1","doi-asserted-by":"crossref","first-page":"6272","DOI":"10.1039\/C4AN01320D","volume":"139","author":"Wang","year":"2014","journal-title":"Analyst"},{"key":"D6AN00800C\/cit25\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13036-017-0054-7","volume":"11","author":"Seo","year":"2017","journal-title":"J. Biol. Eng."},{"key":"D6AN00800C\/cit26\/1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.bios.2016.03.073","volume":"82","author":"Tseng","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"D6AN00800C\/cit27\/1","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.msec.2019.02.001","volume":"99","author":"Lee","year":"2019","journal-title":"Mater. Sci. Eng., C"},{"key":"D6AN00800C\/cit28\/1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.bios.2016.11.061","volume":"93","author":"Ahmad Raston","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"D6AN00800C\/cit29\/1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.bios.2015.03.042","volume":"70","author":"Ahmad Raston","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"D6AN00800C\/cit30\/1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.bios.2019.03.061","volume":"134","author":"Kim","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"D6AN00800C\/cit31\/1","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.bios.2018.10.040","volume":"126","author":"Lee","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"D6AN00800C\/cit32\/1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.sbsr.2016.04.003","volume":"8","author":"Riquelme","year":"2016","journal-title":"Sens. Bio-Sens. Res."},{"key":"D6AN00800C\/cit33\/1","doi-asserted-by":"crossref","first-page":"1700425","DOI":"10.1002\/smll.201700425","volume":"13","author":"Yu","year":"2017","journal-title":"Small"},{"key":"D6AN00800C\/cit34\/1","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1002\/asia.201200222","volume":"7","author":"Chiang","year":"2012","journal-title":"Chem. \u2013 Asian J."},{"key":"D6AN00800C\/cit35\/1","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jviromet.2011.08.011","volume":"178","author":"Wang","year":"2011","journal-title":"J. Virol. Methods"}],"container-title":["The Analyst"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/AN\/article-pdf\/doi\/10.1039\/D6AN00800C\/0\/D6AN00800C.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:49:04Z","timestamp":1790686144000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/AN\/article-lookup\/doi\/10.1039\/D6AN00800C"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":35,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2026,9,29]]}},"URL":"https:\/\/doi.org\/10.1039\/d6an00800c","relation":{},"ISSN":["0003-2654","1364-5528"],"issn-type":[{"value":"0003-2654","type":"print"},{"value":"1364-5528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}