{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:44:03Z","timestamp":1792093443832,"version":"4.4.0"},"reference-count":47,"publisher":"Royal Society of Chemistry (RSC)","issue":"39","license":[{"start":{"date-parts":[[2027,9,1]],"date-time":"2027-09-01T00:00:00Z","timestamp":1819756800000},"content-version":"am","delay-in-days":608,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Anal. Methods"],"abstract":"<jats:p>Schematic representation of the formation of a sandwich immunocomplex in a homogeneous solution for tau detection.<\/jats:p>","DOI":"10.1039\/d6ay01267a","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T15:00:09Z","timestamp":1788274809000},"page":"8917-8928","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A sandwich ECL immunoassay system for tau protein detection using Ru(\n                    <scp>ii<\/scp>\n                    )-AuNP signal probes integrated with copper nanoclusters"],"prefix":"10.1039","volume":"18","author":[{"given":"Arathy B.","family":"K","sequence":"first","affiliation":[{"name":"Department of Chemistry, School of Physical and Mathematical Sciences, University of Kerala, Kariavattom Campus, Thiruvananthapuram-695581, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merin K.","family":"Abraham","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Physical and Mathematical Sciences, University of Kerala, Kariavattom Campus, Thiruvananthapuram-695581, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geneva","family":"Indongo","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Physical and Mathematical Sciences, University of Kerala, Kariavattom Campus, Thiruvananthapuram-695581, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greeshma","family":"Rajeevan","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Physical and Mathematical Sciences, University of Kerala, Kariavattom Campus, Thiruvananthapuram-695581, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dheya Mohammed","family":"Dhahir","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Physical and Mathematical Sciences, University of Kerala, Kariavattom Campus, Thiruvananthapuram-695581, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neena","family":"Haridas","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Physical and Mathematical Sciences, University of Kerala, Kariavattom Campus, Thiruvananthapuram-695581, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neethu","family":"Prakash S","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Physical and Mathematical Sciences, University of Kerala, Kariavattom Campus, Thiruvananthapuram-695581, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajalekshmi","family":"R","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Physical and Mathematical Sciences, University of Kerala, Kariavattom Campus, Thiruvananthapuram-695581, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9848-0465","authenticated-orcid":false,"given":"Dr Sony","family":"George","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Physical and Mathematical Sciences, University of Kerala, Kariavattom Campus, Thiruvananthapuram-695581, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6AY01267A\/cit1\/1","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1038\/nrneurol.2017.96","volume":"13","author":"Elahi","year":"2017","journal-title":"Nat. Rev. Neurol."},{"key":"D6AY01267A\/cit2\/1","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1007\/s44163-025-00358-x","volume":"5","author":"Wahul","year":"2025","journal-title":"Discov. Artif. Intell."},{"key":"D6AY01267A\/cit3\/1","doi-asserted-by":"publisher","first-page":"118884","DOI":"10.1016\/j.bios.2026.118884","volume":"311","author":"Li","year":"2026","journal-title":"Biosens. Bioelectron."},{"key":"D6AY01267A\/cit4\/1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-025-94677-9","volume":"15","author":"Oraby","year":"2025","journal-title":"Sci. Rep."},{"key":"D6AY01267A\/cit5\/1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2026.119004","volume":"312","author":"Feng","year":"2026","journal-title":"Biosens. Bioelectron."},{"key":"D6AY01267A\/cit6\/1","doi-asserted-by":"publisher","first-page":"140391","DOI":"10.1016\/j.snb.2026.140391","volume":"467","author":"Song","year":"2026","journal-title":"Sens. Actuators, B"},{"key":"D6AY01267A\/cit7\/1","doi-asserted-by":"publisher","first-page":"1752","DOI":"10.1038\/s41440-024-01672-0","volume":"47","author":"Ameya","year":"2024","journal-title":"Hypertens. Res."},{"key":"D6AY01267A\/cit8\/1","doi-asserted-by":"publisher","first-page":"6380","DOI":"10.1021\/acssensors.5c02453","volume":"10","author":"Peng","year":"2025","journal-title":"ACS Sens."},{"key":"D6AY01267A\/cit9\/1","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1021\/jacsau.5c00002","volume":"5","author":"Zhou","year":"2025","journal-title":"JACS Au"},{"key":"D6AY01267A\/cit10\/1","doi-asserted-by":"publisher","first-page":"118430","DOI":"10.1016\/j.bios.2026.118430","volume":"298","author":"Xie","year":"2026","journal-title":"Biosens. Bioelectron."},{"key":"D6AY01267A\/cit11\/1","doi-asserted-by":"publisher","first-page":"10853","DOI":"10.1021\/acs.nanolett.5c02255","volume":"25","author":"Wang","year":"2025","journal-title":"Nano Lett."},{"key":"D6AY01267A\/cit12\/1","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1021\/acs.analchem.5c02003","volume":"97","author":"Xu","year":"2025","journal-title":"Anal. Chem."},{"key":"D6AY01267A\/cit13\/1","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1038\/s41380-024-02709-z","volume":"30","author":"Hunter","year":"2025","journal-title":"Mol. Psychiatry"},{"key":"D6AY01267A\/cit14\/1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41467-025-62590-4","volume":"16","author":"Jasodanand","year":"2025","journal-title":"Nat. Commun."},{"key":"D6AY01267A\/cit15\/1","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1038\/s41398-025-03345-z","volume":"15","author":"Wang","year":"2025","journal-title":"Transl. Psychiatry"},{"key":"D6AY01267A\/cit16\/1","doi-asserted-by":"publisher","first-page":"7277","DOI":"10.1039\/d5sc08604c","volume":"17","author":"Ju\u00e1rez-Romero","year":"2026","journal-title":"Chem. Sci."},{"key":"D6AY01267A\/cit17\/1","doi-asserted-by":"publisher","first-page":"16460","DOI":"10.1007\/s12035-025-05255-z","volume":"62","author":"Castillo-Casa\u00f1a","year":"2025","journal-title":"Mol. Neurobiol."},{"key":"D6AY01267A\/cit18\/1","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1080\/14737175.2024.2415985","volume":"25","author":"Parul","year":"2025","journal-title":"Expert Rev. Neurother."},{"key":"D6AY01267A\/cit19\/1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00604-026-07962-3","volume":"193","author":"Preetam","year":"2026","journal-title":"Microchim. Acta"},{"key":"D6AY01267A\/cit20\/1","doi-asserted-by":"publisher","first-page":"118897","DOI":"10.1016\/j.trac.2026.118897","volume":"201","author":"Cai","year":"2026","journal-title":"TrAC, Trends Anal. Chem."},{"key":"D6AY01267A\/cit21\/1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/adsr.202400164","volume":"4","author":"Sinibaldi","year":"2025","journal-title":"Adv. Sens. Res."},{"key":"D6AY01267A\/cit22\/1","doi-asserted-by":"publisher","first-page":"120410","DOI":"10.1016\/j.cca.2025.120410","volume":"576","author":"Vafadar","year":"2025","journal-title":"Clin. Chim. Acta"},{"key":"D6AY01267A\/cit23\/1","doi-asserted-by":"publisher","first-page":"100009","DOI":"10.1016\/j.tjpad.2024.100009","volume":"12","author":"Decaix","year":"2025","journal-title":"J. Prev. Alzheimers Dis."},{"key":"D6AY01267A\/cit24\/1","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1002\/adpr.202200044","volume":"3","author":"Chiavaioli","year":"2022","journal-title":"Adv. Photonics Res."},{"key":"D6AY01267A\/cit25\/1","doi-asserted-by":"publisher","first-page":"3001","DOI":"10.1021\/bm400968x","volume":"14","author":"Zengin","year":"2013","journal-title":"Biomacromolecules"},{"key":"D6AY01267A\/cit26\/1","doi-asserted-by":"publisher","first-page":"2823","DOI":"10.1039\/c4an00204k","volume":"139","author":"Esteves-Villanueva","year":"2014","journal-title":"Analyst"},{"key":"D6AY01267A\/cit27\/1","doi-asserted-by":"publisher","first-page":"7476","DOI":"10.1007\/s12010-024-04960-0","volume":"196","author":"Nazir","year":"2024","journal-title":"Appl. Biochem. Biotechnol."},{"key":"D6AY01267A\/cit28\/1","doi-asserted-by":"publisher","first-page":"6813","DOI":"10.1021\/acs.analchem.5c07069","volume":"98","author":"He","year":"2026","journal-title":"Anal. Chem."},{"key":"D6AY01267A\/cit29\/1","doi-asserted-by":"publisher","first-page":"5195","DOI":"10.1021\/acs.analchem.5c04129","volume":"98","author":"Ran","year":"2026","journal-title":"Anal. Chem."},{"key":"D6AY01267A\/cit30\/1","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1002\/bio.4353","volume":"28","author":"Harshita","year":"2023","journal-title":"Luminescence"},{"key":"D6AY01267A\/cit31\/1","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.aca.2020.02.041","volume":"1114","author":"Shao","year":"2020","journal-title":"Anal. Chim. Acta"},{"key":"D6AY01267A\/cit32\/1","doi-asserted-by":"publisher","first-page":"123611","DOI":"10.1016\/j.talanta.2022.123611","volume":"248","author":"Bezuneh","year":"2022","journal-title":"Talanta"},{"key":"D6AY01267A\/cit33\/1","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1007\/s00604-026-07972-1","volume":"193","author":"Zhai","year":"2026","journal-title":"Microchim. Acta"},{"key":"D6AY01267A\/cit34\/1","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.bios.2018.07.023","volume":"118","author":"Gai","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"D6AY01267A\/cit35\/1","doi-asserted-by":"publisher","first-page":"19271","DOI":"10.1021\/acsanm.3c03758","volume":"6","author":"Wang","year":"2023","journal-title":"ACS Appl. Nano Mater."},{"key":"D6AY01267A\/cit36\/1","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s13404-015-0156-2","volume":"48","author":"Dong","year":"2015","journal-title":"Gold Bull."},{"key":"D6AY01267A\/cit37\/1","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.snb.2013.01.042","volume":"181","author":"Li","year":"2013","journal-title":"Sens. Actuators, B"},{"key":"D6AY01267A\/cit38\/1","doi-asserted-by":"publisher","first-page":"101053","DOI":"10.1016\/j.chphi.2026.101053","volume":"16","author":"Devika","year":"2026","journal-title":"Chem. Phys. Impact"},{"key":"D6AY01267A\/cit39\/1","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.aca.2014.07.019","volume":"287","author":"Yang","year":"2014","journal-title":"Anal. Chim. Acta"},{"key":"D6AY01267A\/cit40\/1","doi-asserted-by":"publisher","first-page":"4176","DOI":"10.1021\/acschemneuro.3c00568","volume":"14","author":"Kong","year":"2023","journal-title":"ACS Chem. Neurosci."},{"key":"D6AY01267A\/cit41\/1","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.jcis.2024.03.125","volume":"665","author":"Jiang","year":"2024","journal-title":"J. Colloid Interface Sci."},{"key":"D6AY01267A\/cit42\/1","doi-asserted-by":"publisher","first-page":"129550","DOI":"10.1016\/j.talanta.2026.129550","volume":"305","author":"Sun","year":"2026","journal-title":"Talanta"},{"key":"D6AY01267A\/cit43\/1","doi-asserted-by":"publisher","first-page":"119018","DOI":"10.1016\/j.bios.2026.119018","volume":"312","author":"Wei","year":"2026","journal-title":"Biosens. Bioelectron."},{"key":"D6AY01267A\/cit44\/1","doi-asserted-by":"publisher","first-page":"100252","DOI":"10.1016\/j.sintl.2023.100252","volume":"5","author":"Tirkey","year":"2024","journal-title":"Sens. Int."},{"key":"D6AY01267A\/cit45\/1","doi-asserted-by":"publisher","first-page":"1850","DOI":"10.1039\/d4ay02013h","volume":"17","author":"Varghese","year":"2025","journal-title":"Anal. Methods"},{"key":"D6AY01267A\/cit46\/1","doi-asserted-by":"publisher","first-page":"127910","DOI":"10.1016\/j.talanta.2025.127910","volume":"291","author":"Dong","year":"2025","journal-title":"Talanta"},{"key":"D6AY01267A\/cit47\/1","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1016\/j.bios.2009.07.018","volume":"25","author":"Gandhi","year":"2009","journal-title":"Biosens. Bioelectron."}],"container-title":["Analytical Methods"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/AY\/article-pdf\/doi\/10.1039\/D6AY01267A\/0\/D6AY01267A.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:45:16Z","timestamp":1792089916000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/AY\/article-lookup\/doi\/10.1039\/D6AY01267A"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":47,"journal-issue":{"issue":"39","published-print":{"date-parts":[[2026,10,15]]}},"URL":"https:\/\/doi.org\/10.1039\/d6ay01267a","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D6AY01267A\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6AY01267A\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6AY01267A\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6AY01267A\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6AY01267A\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6AY01267A\/v2\/review1","asserted-by":"object"}]},"ISSN":["1759-9660","1759-9679"],"issn-type":[{"value":"1759-9660","type":"print"},{"value":"1759-9679","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}