{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:44:04Z","timestamp":1792093444301,"version":"4.4.0"},"reference-count":40,"publisher":"Royal Society of Chemistry (RSC)","issue":"39","license":[{"start":{"date-parts":[[2027,9,10]],"date-time":"2027-09-10T00:00:00Z","timestamp":1820534400000},"content-version":"am","delay-in-days":617,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100005147","name":"Yunnan Science and Technology","doi-asserted-by":"publisher","award":["202201AU070214"],"award-info":[{"award-number":["202201AU070214"]}],"id":[{"id":"10.13039\/501100005147","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Anal. Methods"],"abstract":"<jats:p>An autofluorescence-free sensing system for trypsin is developed based on persistent luminescent nanospheres and gold nanoparticle aggregation.<\/jats:p>","DOI":"10.1039\/d6ay01515h","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T09:57:06Z","timestamp":1789034226000},"page":"9089-9097","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Autofluorescence-free detection of trypsin based on persistent luminescent nanospheres and gold nanoparticle aggregation"],"prefix":"10.1039","volume":"18","author":[{"given":"Yichen","family":"Li","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Kunming University, Kunming, 650214, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Kunming University, Kunming, 650214, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hancan","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Kunming University, Kunming, 650214, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9271-1361","authenticated-orcid":false,"given":"Hongjiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Kunming University, Kunming, 650214, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6AY01515H\/cit1\/1","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1038\/s41467-025-56875-x","volume":"16","author":"Modenbach","year":"2025","journal-title":"Nat. Commun."},{"key":"D6AY01515H\/cit2\/1","doi-asserted-by":"crossref","first-page":"148996","DOI":"10.1016\/j.ijbiomac.2025.148996","volume":"334","author":"Chen","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"D6AY01515H\/cit3\/1","doi-asserted-by":"crossref","first-page":"142507","DOI":"10.1016\/j.ijbiomac.2025.142507","volume":"308","author":"Liu","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"D6AY01515H\/cit4\/1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/s43094-024-00709-y","volume":"10","author":"Famutimi","year":"2024","journal-title":"Future J. Pharm. Sci."},{"key":"D6AY01515H\/cit5\/1","doi-asserted-by":"crossref","first-page":"13649","DOI":"10.1021\/acs.analchem.3c02543","volume":"95","author":"Woessmann","year":"2023","journal-title":"Anal. Chem."},{"key":"D6AY01515H\/cit6\/1","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1021\/acsptsci.3c00263","volume":"7","author":"Xiang","year":"2023","journal-title":"ACS Pharmacol. Transl. Sci."},{"key":"D6AY01515H\/cit7\/1","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1080\/10408347.2020.1846490","volume":"52","author":"Kaur","year":"2022","journal-title":"Crit. Rev. Anal. Chem."},{"key":"D6AY01515H\/cit8\/1","doi-asserted-by":"crossref","first-page":"e360","DOI":"10.1097\/MPA.0000000000002445","volume":"54","author":"Gummadi","year":"2025","journal-title":"Pancreas"},{"key":"D6AY01515H\/cit9\/1","doi-asserted-by":"crossref","first-page":"4417","DOI":"10.3748\/wjg.v30.i41.4417","volume":"30","author":"Gukovskaya","year":"2024","journal-title":"World J. Gastroenterol."},{"key":"D6AY01515H\/cit10\/1","doi-asserted-by":"crossref","first-page":"126819","DOI":"10.1016\/j.talanta.2024.126819","volume":"281","author":"Li","year":"2025","journal-title":"Talanta"},{"key":"D6AY01515H\/cit11\/1","doi-asserted-by":"crossref","first-page":"10494","DOI":"10.1021\/acs.analchem.5c02187","volume":"97","author":"Ning","year":"2025","journal-title":"Anal. Chem."},{"key":"D6AY01515H\/cit12\/1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.3390\/bios11040117","volume":"11","author":"Piovarci","year":"2021","journal-title":"Biosensors"},{"key":"D6AY01515H\/cit13\/1","doi-asserted-by":"crossref","first-page":"127759","DOI":"10.1016\/j.foodchem.2020.127759","volume":"337","author":"Melikishvili","year":"2021","journal-title":"Food Chem."},{"key":"D6AY01515H\/cit14\/1","doi-asserted-by":"crossref","first-page":"20549","DOI":"10.1021\/acs.analchem.5c04170","volume":"97","author":"Lv","year":"2025","journal-title":"Anal. Chem."},{"key":"D6AY01515H\/cit15\/1","doi-asserted-by":"crossref","first-page":"106955","DOI":"10.1016\/j.microc.2021.106955","volume":"172","author":"Roushani","year":"2022","journal-title":"Microchem. J."},{"key":"D6AY01515H\/cit16\/1","doi-asserted-by":"crossref","first-page":"127973","DOI":"10.1016\/j.saa.2026.127973","volume":"360","author":"Liu","year":"2026","journal-title":"Spectrochim. Acta, Part A"},{"key":"D6AY01515H\/cit17\/1","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.1021\/acssensors.3c00297","volume":"8","author":"Park","year":"2023","journal-title":"ACS Sens."},{"key":"D6AY01515H\/cit18\/1","doi-asserted-by":"crossref","first-page":"458","DOI":"10.3390\/bios14100458","volume":"14","author":"Balyan","year":"2024","journal-title":"Biosensors"},{"key":"D6AY01515H\/cit19\/1","doi-asserted-by":"crossref","first-page":"108457","DOI":"10.1016\/j.microc.2023.108457","volume":"187","author":"Zheng","year":"2023","journal-title":"Microchem. J."},{"key":"D6AY01515H\/cit20\/1","doi-asserted-by":"crossref","first-page":"5239","DOI":"10.1007\/s00216-021-03496-0","volume":"413","author":"Yin","year":"2021","journal-title":"Anal. Bioanal. Chem."},{"key":"D6AY01515H\/cit21\/1","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1039\/D1AN02138A","volume":"147","author":"Sun","year":"2022","journal-title":"Analyst"},{"key":"D6AY01515H\/cit22\/1","doi-asserted-by":"crossref","first-page":"136037","DOI":"10.1016\/j.colsurfa.2024.136037","volume":"708","author":"Wang","year":"2025","journal-title":"Colloids Surf., A"},{"key":"D6AY01515H\/cit23\/1","doi-asserted-by":"crossref","first-page":"114919","DOI":"10.1016\/j.microc.2025.114919","volume":"217","author":"Chang","year":"2025","journal-title":"Microchem. J."},{"key":"D6AY01515H\/cit24\/1","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/s00604-023-05754-7","volume":"190","author":"Wu","year":"2023","journal-title":"Mikrochim. Acta"},{"key":"D6AY01515H\/cit25\/1","doi-asserted-by":"crossref","first-page":"2916","DOI":"10.1021\/acsanm.5c05378","volume":"9","author":"Yin","year":"2026","journal-title":"ACS Appl. Nano Mater."},{"key":"D6AY01515H\/cit26\/1","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1021\/acs.accounts.7b00619","volume":"51","author":"Sun","year":"2018","journal-title":"Acc. Chem. Res."},{"key":"D6AY01515H\/cit27\/1","doi-asserted-by":"crossref","first-page":"6302","DOI":"10.1021\/acs.nanolett.5c01138","volume":"25","author":"Wei","year":"2025","journal-title":"Nano Lett."},{"key":"D6AY01515H\/cit28\/1","doi-asserted-by":"crossref","first-page":"8071","DOI":"10.1039\/D0TB01272F","volume":"8","author":"Chen","year":"2020","journal-title":"J. Mater. Chem. B"},{"key":"D6AY01515H\/cit29\/1","doi-asserted-by":"crossref","first-page":"147740","DOI":"10.1016\/j.cej.2023.147740","volume":"480","author":"Fu","year":"2024","journal-title":"Chem. Eng. J."},{"key":"D6AY01515H\/cit30\/1","doi-asserted-by":"crossref","first-page":"118070","DOI":"10.1016\/j.bios.2025.118070","volume":"292","author":"Wang","year":"2026","journal-title":"Biosens. Bioelectron."},{"key":"D6AY01515H\/cit31\/1","doi-asserted-by":"crossref","first-page":"100193","DOI":"10.1016\/j.asems.2026.100193","volume":"5","author":"Zhao","year":"2026","journal-title":"Adv. Sens. Energy Mater."},{"key":"D6AY01515H\/cit32\/1","doi-asserted-by":"crossref","first-page":"127553","DOI":"10.1016\/j.saa.2026.127553","volume":"352","author":"Zhang","year":"2026","journal-title":"Spectrochim. Acta, Part A"},{"key":"D6AY01515H\/cit33\/1","doi-asserted-by":"crossref","first-page":"344813","DOI":"10.1016\/j.aca.2025.344813","volume":"1381","author":"Huang","year":"2026","journal-title":"Anal. Chim. Acta"},{"key":"D6AY01515H\/cit34\/1","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.pdpdt.2016.08.012","volume":"16","author":"Homayoni","year":"2016","journal-title":"Photodiagn. Photodyn. Ther."},{"key":"D6AY01515H\/cit35\/1","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1016\/j.optmat.2008.12.020","volume":"31","author":"Carlson","year":"2009","journal-title":"Opt. Mater."},{"key":"D6AY01515H\/cit36\/1","doi-asserted-by":"crossref","first-page":"3924","DOI":"10.1021\/ac5000587","volume":"86","author":"Li","year":"2014","journal-title":"Anal. Chem."},{"key":"D6AY01515H\/cit37\/1","doi-asserted-by":"crossref","first-page":"112211","DOI":"10.1016\/j.microc.2024.112211","volume":"207","author":"Zhang","year":"2024","journal-title":"Microchem. J."},{"key":"D6AY01515H\/cit38\/1","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.snb.2018.07.023","volume":"273","author":"Xu","year":"2018","journal-title":"Sens. Actuators B: Chem."},{"key":"D6AY01515H\/cit39\/1","doi-asserted-by":"crossref","first-page":"117732","DOI":"10.1016\/j.microc.2026.117732","volume":"224","author":"Li","year":"2026","journal-title":"Microchem. J."},{"key":"D6AY01515H\/cit40\/1","doi-asserted-by":"crossref","first-page":"260","DOI":"10.3390\/nano8040260","volume":"8","author":"Xia","year":"2018","journal-title":"Nanomaterials"}],"container-title":["Analytical Methods"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/AY\/article-pdf\/doi\/10.1039\/D6AY01515H\/0\/D6AY01515H.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:44:56Z","timestamp":1792089896000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/AY\/article-lookup\/doi\/10.1039\/D6AY01515H"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":40,"journal-issue":{"issue":"39","published-print":{"date-parts":[[2026,10,15]]}},"URL":"https:\/\/doi.org\/10.1039\/d6ay01515h","relation":{},"ISSN":["1759-9660","1759-9679"],"issn-type":[{"value":"1759-9660","type":"print"},{"value":"1759-9679","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}