{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:04:45Z","timestamp":1787069085523,"version":"build-2736575974"},"reference-count":145,"publisher":"Royal Society of Chemistry (RSC)","issue":"12","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"vor","delay-in-days":113,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100010663","name":"H2020 European Research Council","doi-asserted-by":"publisher","award":["268476"],"award-info":[{"award-number":["268476"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Biomater. Sci."],"abstract":"<jats:p>A GMP-compliant amorphous polyphosphate formulation acts as an energy-delivering biomaterial that promotes ATP-dependent skin regeneration, accelerating chronic wound healing and enhancing hair growth in human, veterinary and preclinical models.<\/jats:p>","DOI":"10.1039\/d6bm00151c","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T14:21:02Z","timestamp":1777040462000},"page":"3181-3199","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A GMP-compliant formulation of regeneratively active polyphosphate for wound healing and skin regeneration"],"prefix":"10.1039","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8223-3689","authenticated-orcid":false,"given":"Werner E. G.","family":"M\u00fcller","sequence":"first","affiliation":[{"name":"ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2383-6412","authenticated-orcid":false,"given":"Meik","family":"Neufurth","sequence":"additional","affiliation":[{"name":"ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1314-4314","authenticated-orcid":false,"given":"Xiaoqin","family":"La","sequence":"additional","affiliation":[{"name":"Institutes of Biomedical Sciences, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education of China and Key Laboratory of Medical Molecular Cell Biology of Shanxi Province, Shanxi University, No. 92 Wucheng Road, 030006 Taiyuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8217-5645","authenticated-orcid":false,"given":"Hadrian","family":"Nassabi","sequence":"additional","affiliation":[{"name":"Department of Dermatology with Plastic Surgery, SRH Wald-Klinikum Gera GmbH, Friedens Street 122, D-07548 Gera, Germany"},{"name":"Department of Dermatology, University Medical Center of the Johannes Gutenberg University, Langenbeck Street 1, D-55131 Mainz, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathias","family":"Br\u00f6sicke","sequence":"additional","affiliation":[{"name":"Academy of Non-Profit Sciences in Erfurt, Gotthardt Street 21, 99084 Erfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Dobmeyer","sequence":"additional","affiliation":[{"name":"Galenus GH AG, Rain Street 7, 6052 Hergiswil, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8146-2332","authenticated-orcid":false,"given":"Rafael","family":"Mu\u00f1oz-Esp\u00ed","sequence":"additional","affiliation":[{"name":"Institute of Materials Science (ICMUV), Universitat de Val\u00e8ncia, C\/Catedr\u00e0tic Jos\u00e9 Beltr\u00e1n 2, 46980 Paterna - Val\u00e8ncia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7416-1662","authenticated-orcid":false,"given":"Changxin","family":"Wu","sequence":"additional","affiliation":[{"name":"Institutes of Biomedical Sciences, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education of China and Key Laboratory of Medical Molecular Cell Biology of Shanxi Province, Shanxi University, No. 92 Wucheng Road, 030006 Taiyuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4378-3861","authenticated-orcid":false,"given":"Hiroshi","family":"Ushijima","sequence":"additional","affiliation":[{"name":"Division of Microbiology, Department of Pathology and Microbiology, Nihon University-School of Medicine, 30-1 Oyaguchi-Kamicho, Itabashi-Ku, 173-2610, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0992-6427","authenticated-orcid":false,"given":"Heinz C.","family":"Schr\u00f6der","sequence":"additional","affiliation":[{"name":"ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1796-6314","authenticated-orcid":false,"given":"Xiaohong","family":"Wang","sequence":"additional","affiliation":[{"name":"ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6BM00151C\/cit1\/1","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1111\/j.1753-4887.2010.00304.x","volume":"68","author":"Popkin","year":"2010","journal-title":"Nutr. Rev."},{"key":"D6BM00151C\/cit2\/1","doi-asserted-by":"crossref","first-page":"a023267","DOI":"10.1101\/cshperspect.a023267","volume":"5","author":"Takeo","year":"2015","journal-title":"Cold Spring Harbor Perspect. Med."},{"key":"D6BM00151C\/cit3\/1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S1067-2516(02)80024-2","volume":"41","author":"Page","year":"2002","journal-title":"J. Foot Ankle Surg."},{"key":"D6BM00151C\/cit4\/1","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.amjsurg.2006.08.069","volume":"193","author":"Chiang","year":"2007","journal-title":"Am. J. Surg."},{"key":"D6BM00151C\/cit5\/1","doi-asserted-by":"crossref","first-page":"5262","DOI":"10.7150\/thno.100622","volume":"14","author":"M\u00fcller","year":"2024","journal-title":"Theranostics"},{"key":"D6BM00151C\/cit6\/1","doi-asserted-by":"crossref","first-page":"7904","DOI":"10.1073\/pnas.86.20.7904","volume":"86","author":"Huang","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6BM00151C\/cit7\/1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0006-291X(90)91938-O","volume":"166","author":"Wang","year":"1990","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"D6BM00151C\/cit8\/1","doi-asserted-by":"crossref","first-page":"44638","DOI":"10.1074\/jbc.M203012200","volume":"277","author":"Gerasimovskaya","year":"2002","journal-title":"J. Biol. Chem."},{"key":"D6BM00151C\/cit9\/1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12963-024-00337-x","volume":"22","author":"Voeltz","year":"2024","journal-title":"Popul. Health Metr."},{"key":"D6BM00151C\/cit10\/1","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/wrr.12683","volume":"27","author":"Olsson","year":"2019","journal-title":"Wound Repair Regen."},{"key":"D6BM00151C\/cit11\/1","doi-asserted-by":"crossref","first-page":"e70748","DOI":"10.1111\/iwj.70748","volume":"22","author":"Redmond","year":"2025","journal-title":"Int. Wound J."},{"key":"D6BM00151C\/cit12\/1","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1080\/13696998.2023.2232256","volume":"26","author":"Carter","year":"2023","journal-title":"J. Med. Econ."},{"key":"D6BM00151C\/cit13\/1","doi-asserted-by":"crossref","first-page":"3935","DOI":"10.1111\/iwj.14491","volume":"20","author":"Queen","year":"2023","journal-title":"Int. Wound J."},{"key":"D6BM00151C\/cit14\/1","doi-asserted-by":"crossref","first-page":"100313","DOI":"10.1016\/j.ijnsa.2025.100313","volume":"8","author":"D\u00edaz-Herrera","year":"2025","journal-title":"Int. J. Nurs. Stud. Adv."},{"key":"D6BM00151C\/cit15\/1","doi-asserted-by":"crossref","first-page":"918042","DOI":"10.3389\/fphys.2022.918042","volume":"13","author":"Li","year":"2022","journal-title":"Front. Physiol."},{"key":"D6BM00151C\/cit16\/1","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1242\/jcs.200741","volume":"130","author":"De Marchi","year":"2017","journal-title":"J. Cell Sci."},{"key":"D6BM00151C\/cit17\/1","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.molcel.2017.05.032","volume":"66","author":"Garcia","year":"2017","journal-title":"Mol. Cell"},{"key":"D6BM00151C\/cit18\/1","doi-asserted-by":"crossref","first-page":"102077","DOI":"10.1016\/j.molmet.2024.102077","volume":"91","author":"Da Costa","year":"2025","journal-title":"Mol. Metab."},{"key":"D6BM00151C\/cit19\/1","first-page":"50","volume":"20","author":"Mikirova","year":"2004","journal-title":"J. Orthomol. Med."},{"key":"D6BM00151C\/cit20\/1","doi-asserted-by":"crossref","first-page":"20120101","DOI":"10.1098\/rsfs.2012.0101","volume":"3","author":"Falzoni","year":"2013","journal-title":"Interface Focus"},{"key":"D6BM00151C\/cit21\/1","doi-asserted-by":"crossref","first-page":"2309528","DOI":"10.1002\/smll.202309528","volume":"20","author":"M\u00fcller","year":"2024","journal-title":"Small"},{"key":"D6BM00151C\/cit22\/1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0006-3002(56)90280-3","volume":"20","author":"Kornberg","year":"1956","journal-title":"Biochim. Biophys. Acta"},{"key":"D6BM00151C\/cit23\/1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1042\/BIO04104022","volume":"41","author":"M\u00fcller","year":"2019","journal-title":"Biochemist"},{"key":"D6BM00151C\/cit24\/1","first-page":"1","volume":"61","author":"M\u00fcller","year":"2022","journal-title":"Prog. Mol. Subcell. Biol."},{"key":"D6BM00151C\/cit25\/1","doi-asserted-by":"crossref","first-page":"019","DOI":"10.53771\/ijlsra.2025.8.1.0024","volume":"8","author":"Vulla","year":"2025","journal-title":"Int. J. Life Sci. Res. Arch."},{"key":"D6BM00151C\/cit26\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11084-021-09604-5","volume":"51","author":"Glonek","year":"2021","journal-title":"Orig. Life Evol. Biosph."},{"key":"D6BM00151C\/cit27\/1","doi-asserted-by":"crossref","first-page":"1801170","DOI":"10.1002\/smll.201801170","volume":"14","author":"M\u00fcller","year":"2018","journal-title":"Small"},{"key":"D6BM00151C\/cit28\/1","doi-asserted-by":"crossref","first-page":"100404","DOI":"10.1016\/j.mtbio.2022.100404","volume":"16","author":"M\u00fcller","year":"2022","journal-title":"Mater. Today Bio"},{"key":"D6BM00151C\/cit29\/1","doi-asserted-by":"crossref","first-page":"5825","DOI":"10.2147\/IJN.S389819","volume":"17","author":"Schr\u00f6der","year":"2022","journal-title":"Int. J. Nanomed."},{"key":"D6BM00151C\/cit30\/1","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/zaac.19572910120","volume":"291","author":"Thilo","year":"1957","journal-title":"Z. Anorg. Allg. Chem."},{"key":"D6BM00151C\/cit31\/1","doi-asserted-by":"crossref","first-page":"2838","DOI":"10.1021\/jp9730252","volume":"102","author":"De Jager","year":"1998","journal-title":"J. Phys. Chem. A"},{"key":"D6BM00151C\/cit32\/1","doi-asserted-by":"crossref","first-page":"e12899","DOI":"10.1111\/jeu.12899","volume":"69","author":"Docampo","year":"2022","journal-title":"J. Eukaryot. Microbiol."},{"key":"D6BM00151C\/cit33\/1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1146\/annurev.biochem.68.1.89","volume":"68","author":"Kornberg","year":"1999","journal-title":"Annu. Rev. Biochem."},{"key":"D6BM00151C\/cit34\/1","doi-asserted-by":"crossref","first-page":"11734","DOI":"10.1016\/S0021-9258(19)38459-5","volume":"265","author":"Ahn","year":"1990","journal-title":"J. Biol. Chem."},{"key":"D6BM00151C\/cit35\/1","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1242\/jcs.184382","volume":"129","author":"Desfoug\u00e8res","year":"2016","journal-title":"J. Cell Sci."},{"key":"D6BM00151C\/cit36\/1","doi-asserted-by":"crossref","first-page":"12337","DOI":"10.1021\/acs.chemrev.9b00460","volume":"119","author":"M\u00fcller","year":"2019","journal-title":"Chem. Rev."},{"key":"D6BM00151C\/cit37\/1","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1359\/jbmr.1998.13.5.803","volume":"13","author":"Leyhausen","year":"1998","journal-title":"J. Bone Miner. Res."},{"key":"D6BM00151C\/cit38\/1","doi-asserted-by":"crossref","first-page":"E39","DOI":"10.1002\/term.1745","volume":"9","author":"M\u00fcller","year":"2015","journal-title":"J. Tissue Eng. Regen. Med."},{"key":"D6BM00151C\/cit39\/1","doi-asserted-by":"crossref","first-page":"035005","DOI":"10.1088\/1748-6041\/11\/3\/035005","volume":"11","author":"Wang","year":"2016","journal-title":"Biomed. Mater."},{"key":"D6BM00151C\/cit40\/1","doi-asserted-by":"crossref","first-page":"e0010223","DOI":"10.1128\/mbio.00102-23","volume":"14","author":"Kim","year":"2023","journal-title":"mBio"},{"key":"D6BM00151C\/cit41\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mib.2014.12.004","volume":"24","author":"Gray","year":"2015","journal-title":"Curr. Opin. Microbiol."},{"key":"D6BM00151C\/cit42\/1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1042\/BST20190328","volume":"48","author":"Desfoug\u00e8res","year":"2020","journal-title":"Biochem. Soc. Trans."},{"key":"D6BM00151C\/cit43\/1","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.3390\/ijms18102154","volume":"18","author":"M\u00fcller","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"D6BM00151C\/cit44\/1","doi-asserted-by":"crossref","first-page":"6193","DOI":"10.7150\/thno.59535","volume":"11","author":"Schepler","year":"2021","journal-title":"Theranostics"},{"key":"D6BM00151C\/cit45\/1","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1007\/s00424-024-03027-7","volume":"476","author":"Volk","year":"2024","journal-title":"Pfl\u00fcgers Arch."},{"key":"D6BM00151C\/cit46\/1","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1038\/jid.2010.291","volume":"131","author":"Ansell","year":"2011","journal-title":"J. Invest. Dermatol."},{"key":"D6BM00151C\/cit47\/1","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/jid.2010.409","volume":"131","author":"Aber","year":"2011","journal-title":"J. Invest. Dermatol."},{"key":"D6BM00151C\/cit48\/1","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1021\/ja01847a028","volume":"63","author":"Partridge","year":"1941","journal-title":"J. Am. Chem. Soc."},{"key":"D6BM00151C\/cit49\/1","doi-asserted-by":"crossref","first-page":"eabe5040","DOI":"10.1126\/scisignal.abe5040","volume":"14","author":"Ferrucci","year":"2021","journal-title":"Sci. Signal."},{"key":"D6BM00151C\/cit50\/1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1093\/jnci\/59.1.221","volume":"59","author":"Fogh","year":"1977","journal-title":"J. Nat. Cancer Inst."},{"key":"D6BM00151C\/cit51\/1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/febs.13552","volume":"283","author":"M\u00fcller","year":"2016","journal-title":"FEBS J."},{"key":"D6BM00151C\/cit52\/1","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s00223-013-9833-4","volume":"94","author":"Wang","year":"2014","journal-title":"Calcif. Tissue Int."},{"key":"D6BM00151C\/cit53\/1","volume-title":"Assay Guidance Manual","year":"2004","unstructured":"Assay Guidance Manual , ed.  S. Markossian ,  A. Grossman ,  H. Baskir ,  M. Arkin ,  D. Auld ,  C. Austin ,  J. Baell ,  K. Brimacombe ,  T. D. Y. Chung ,  N. P. Coussens ,  J. L. Dahlin ,  V. Devanarayan ,  T. L. Foley ,  M. Glicksman ,  K. Gorshkov ,  S. Grotegut ,  M. D. Hall ,  S. Hoare ,  J. Inglese ,  P. W. Iversen ,  M. Lal-Nag ,  Z. Li ,  J. R. Manro ,  J. McGee ,  A. Norvil ,  M. Pearson ,  T. Riss ,  P. Saradjian ,  G. S. Sittampalam ,  M. A. Tarselli ,  O. J. Trask Jr. ,  J. R. Weidner ,  M. J. Wildey ,  K. Wilson ,  M. Xia  and  X. Xu ,  Eli Lilly & Company and the National Center for Advancing Translational Sciences ,  Indiana ,  2004"},{"key":"D6BM00151C\/cit54\/1","doi-asserted-by":"crossref","first-page":"5210","DOI":"10.3390\/molecules25215210","volume":"25","author":"Wang","year":"2020","journal-title":"Molecules"},{"key":"D6BM00151C\/cit55\/1","volume-title":"Handbook of Direct Immunofluorescence: A Pattern-Based Approach to Skin and Mucosal Biopsies","author":"Douglas","year":"2018","unstructured":"F.Douglas ,  P.May ,  A.Aleodor  and  D. P.David ,  Handbook of Direct Immunofluorescence: A Pattern-Based Approach to Skin and Mucosal Biopsies ,  JP Medical Ltd. ,  Z\u00fcrich ,  2018"},{"key":"D6BM00151C\/cit56\/1","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1016\/j.actbio.2011.03.007","volume":"7","author":"M\u00fcller","year":"2011","journal-title":"Acta Biomater."},{"key":"D6BM00151C\/cit57\/1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.7150\/thno.67148","volume":"12","author":"Schepler","year":"2022","journal-title":"Theranostics"},{"key":"D6BM00151C\/cit58\/1","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.aca.2018.04.054","volume":"1025","author":"Pavankumar","year":"2018","journal-title":"Anal. Chim. Acta"},{"key":"D6BM00151C\/cit59\/1","doi-asserted-by":"crossref","first-page":"4870","DOI":"10.1242\/dev.101725","volume":"140","author":"Veniaminova","year":"2013","journal-title":"Development"},{"key":"D6BM00151C\/cit60\/1","doi-asserted-by":"crossref","first-page":"2514","DOI":"10.1161\/ATVBAHA.107.151456","volume":"27","author":"Woodfin","year":"2007","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"D6BM00151C\/cit61\/1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/110241599750007441","volume":"165","author":"Bonnema","year":"1999","journal-title":"Eur. J. Surg."},{"key":"D6BM00151C\/cit62\/1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/jemt.1070260603","volume":"26","author":"Bray","year":"1993","journal-title":"Microsc. Res. Tech."},{"key":"D6BM00151C\/cit63\/1","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jmst.2022.07.018","volume":"135","author":"M\u00fcller","year":"2023","journal-title":"J. Mater. Sci. Technol."},{"key":"D6BM00151C\/cit64\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1122\/1.4935127","volume":"60","author":"Momeni","year":"2016","journal-title":"J. Rheol."},{"key":"D6BM00151C\/cit65\/1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1053\/jvet.2002.33585","volume":"31","author":"Dart","year":"2002","journal-title":"Vet. Surg."},{"key":"D6BM00151C\/cit66\/1","author":"WMA","unstructured":"WMA ,  Declaration of Helsinki \u2013 Ethical Principles for Medical Research Involving Human Participants, The World Medical Association, Ferney-Voltaire ,  https:\/\/www.wma.net\/policies-post\/wma-declaration-of-helsinki\/ , (accessed October 2024)"},{"key":"D6BM00151C\/cit67\/1","first-page":"33","volume":"L276","author":"EU","year":"2010","journal-title":"Off. J. Eur. Union"},{"key":"D6BM00151C\/cit68\/1","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1242\/jcs.204941","volume":"130","author":"M\u00fcller","year":"2017","journal-title":"J. Cell Sci."},{"key":"D6BM00151C\/cit69\/1","doi-asserted-by":"crossref","first-page":"29667","DOI":"10.1074\/jbc.M505381200","volume":"280","author":"Burrell","year":"2005","journal-title":"J. Biol. Chem."},{"key":"D6BM00151C\/cit70\/1","first-page":"e61616","volume":"162","author":"Rhea","year":"2020","journal-title":"J. Visualized Exp."},{"key":"D6BM00151C\/cit71\/1","doi-asserted-by":"crossref","first-page":"300","DOI":"10.3390\/polym9070300","volume":"9","author":"M\u00fcller","year":"2017","journal-title":"Polymers"},{"key":"D6BM00151C\/cit72\/1","doi-asserted-by":"crossref","first-page":"e4514","DOI":"10.21769\/BioProtoc.4514","volume":"12","author":"Shannon","year":"2022","journal-title":"Bio. Protoc."},{"key":"D6BM00151C\/cit73\/1","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.actbio.2020.10.023","volume":"118","author":"M\u00fcller","year":"2020","journal-title":"Acta Biomater."},{"key":"D6BM00151C\/cit74\/1","doi-asserted-by":"crossref","first-page":"pdb.prot4986","DOI":"10.1101\/pdb.prot4986","volume":"2008","author":"Fischer","year":"2008","journal-title":"Cold Spring Harb. Protoc."},{"key":"D6BM00151C\/cit75\/1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s00418-022-02098-w","volume":"158","author":"Meng","year":"2022","journal-title":"Histochem. Cell Biol."},{"key":"D6BM00151C\/cit76\/1","doi-asserted-by":"crossref","first-page":"112061","DOI":"10.1016\/j.msec.2021.112061","volume":"124","author":"Barbosa","year":"2021","journal-title":"Mater. Sci. Eng., C"},{"key":"D6BM00151C\/cit77\/1","doi-asserted-by":"crossref","first-page":"10232","DOI":"10.1038\/s41598-022-13452-2","volume":"12","author":"Chen","year":"2022","journal-title":"Sci. Rep."},{"key":"D6BM00151C\/cit78\/1","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1007\/s11706-009-0036-x","volume":"3","author":"Weiner","year":"2009","journal-title":"Front. Mater. Sci. China"},{"key":"D6BM00151C\/cit79\/1","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/j.1365-2621.1965.tb01783.x","volume":"30","author":"Batra","year":"2006","journal-title":"J. Food Sci."},{"key":"D6BM00151C\/cit80\/1","doi-asserted-by":"crossref","first-page":"8735","DOI":"10.3168\/jds.2017-12764","volume":"100","author":"Barth","year":"2017","journal-title":"J. Dairy Sci."},{"key":"D6BM00151C\/cit81\/1","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1021\/ja01611a021","volume":"77","author":"Strauss","year":"1955","journal-title":"J. Am. Chem. Soc."},{"key":"D6BM00151C\/cit82\/1","doi-asserted-by":"crossref","first-page":"3255","DOI":"10.1042\/BCJ20180535","volume":"475","author":"M\u00fcller","year":"2018","journal-title":"Biochem. J."},{"key":"D6BM00151C\/cit83\/1","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1111\/jth.15066","volume":"18","author":"Suess","year":"2020","journal-title":"J. Thromb. Haemost."},{"key":"D6BM00151C\/cit84\/1","doi-asserted-by":"crossref","first-page":"4353","DOI":"10.1182\/blood-2010-01-266791","volume":"116","author":"Smith","year":"2010","journal-title":"Blood"},{"key":"D6BM00151C\/cit85\/1","doi-asserted-by":"crossref","first-page":"6963","DOI":"10.1182\/blood-2011-07-368811","volume":"118","author":"Choi","year":"2011","journal-title":"Blood"},{"key":"D6BM00151C\/cit86\/1","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/j.cell.2009.11.001","volume":"139","author":"M\u00fcller","year":"2009","journal-title":"Cell"},{"key":"D6BM00151C\/cit87\/1","first-page":"274","volume-title":"Phosphorus: Chemistry, Biochemistry and Technology","author":"Corbridge","year":"2013","unstructured":"D. E. C.Corbridge ,  Phosphorus: Chemistry, Biochemistry and Technology , 6th edn,  CRC Press ,  Boca Raton, USA ,  2013 , p.  274"},{"key":"D6BM00151C\/cit88\/1","doi-asserted-by":"crossref","DOI":"10.6028\/NBS.MONO.25-2","volume-title":"Standard X-ray diffraction powder patterns, Monograph 25\u2014Section 2","author":"Swanson","year":"1963","unstructured":"E. H.Swanson ,  M. C.Morris ,  R. P.Stinchfield  and  E. H.Evans ,  Standard X-ray diffraction powder patterns, Monograph 25\u2014Section 2 ,  National Bureau of Standards ,  Washington DC, USA ,  1963"},{"key":"D6BM00151C\/cit89\/1","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1080\/10717544.2021.1995078","volume":"28","author":"Alshehri","year":"2021","journal-title":"Drug Delivery"},{"key":"D6BM00151C\/cit90\/1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/nature07039","volume":"453","author":"Gurtner","year":"2008","journal-title":"Nature"},{"key":"D6BM00151C\/cit91\/1","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1096\/fj.04-2978fje","volume":"19","author":"Opalenik","year":"2005","journal-title":"FASEB J."},{"key":"D6BM00151C\/cit92\/1","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.cvsm.2006.02.001","volume":"36","author":"Bohling","year":"2006","journal-title":"Vet. Clin. North Am. Small Anim. Pract."},{"key":"D6BM00151C\/cit93\/1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1524-475X.2010.00639.x","volume":"19","author":"Celeste","year":"2011","journal-title":"Wound Repair Regen."},{"key":"D6BM00151C\/cit94\/1","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.devcel.2014.11.012","volume":"31","author":"Demaria","year":"2014","journal-title":"Dev. Cell"},{"key":"D6BM00151C\/cit95\/1","doi-asserted-by":"crossref","first-page":"408","DOI":"10.4103\/2229-5178.137830","volume":"5","author":"Rai","year":"2014","journal-title":"Indian Dermatol. Online J."},{"key":"D6BM00151C\/cit96\/1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0009-8981(90)90031-M","volume":"186","author":"Harris","year":"1990","journal-title":"Clin. Chim. Acta"},{"key":"D6BM00151C\/cit97\/1","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S0016-5085(72)80154-9","volume":"62","author":"Kaplan","year":"1972","journal-title":"Gastroenterology"},{"key":"D6BM00151C\/cit98\/1","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s00223-022-01048-x","volume":"112","author":"Makris","year":"2023","journal-title":"Calcif. Tissue Int."},{"key":"D6BM00151C\/cit99\/1","doi-asserted-by":"crossref","first-page":"440","DOI":"10.3390\/cells14060440","volume":"14","author":"Lee","year":"2025","journal-title":"Cells"},{"key":"D6BM00151C\/cit100\/1","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/nature05766","volume":"447","author":"Ito","year":"2007","journal-title":"Nature"},{"key":"D6BM00151C\/cit101\/1","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1038\/nm1328","volume":"11","author":"Ito","year":"2005","journal-title":"Nat. Med."},{"key":"D6BM00151C\/cit102\/1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.semcdb.2013.12.005","volume":"25\u201326","author":"Rompolas","year":"2014","journal-title":"Semin. Cell Dev. Biol."},{"key":"D6BM00151C\/cit103\/1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1046\/j.0022-202X.2003.22110.x","volume":"122","author":"Otberg","year":"2004","journal-title":"J. Invest. Dermatol."},{"key":"D6BM00151C\/cit104\/1","doi-asserted-by":"crossref","first-page":"R132","DOI":"10.1016\/j.cub.2008.12.005","volume":"19","author":"Schneider","year":"2009","journal-title":"Curr. Biol."},{"key":"D6BM00151C\/cit105\/1","doi-asserted-by":"crossref","first-page":"5004","DOI":"10.3390\/jcm12155004","volume":"12","author":"Pinedo-Moraleda","year":"2023","journal-title":"J. Clin. Med."},{"key":"D6BM00151C\/cit106\/1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jdermsci.2006.12.002","volume":"46","author":"Ohyama","year":"2007","journal-title":"J. Dermatol. Sci."},{"key":"D6BM00151C\/cit107\/1","first-page":"e37439","volume":"15","author":"Talebzadeh","year":"2023","journal-title":"Cureus"},{"key":"D6BM00151C\/cit108\/1","doi-asserted-by":"crossref","first-page":"eabd2893","DOI":"10.1126\/science.abd2893","volume":"373","author":"Choa","year":"2021","journal-title":"Science"},{"key":"D6BM00151C\/cit109\/1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF02440188","volume":"94","author":"Apte","year":"1990","journal-title":"Histochemistry"},{"key":"D6BM00151C\/cit110\/1","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1046\/j.0022-202x.2001.01670.x","volume":"118","author":"Millar","year":"2002","journal-title":"J. Invest. Dermatol."},{"key":"D6BM00151C\/cit111\/1","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1242\/dev.090662","volume":"140","author":"Chi","year":"2013","journal-title":"Development"},{"key":"D6BM00151C\/cit112\/1","doi-asserted-by":"crossref","first-page":"15821","DOI":"10.1074\/jbc.M512840200","volume":"281","author":"Kultti","year":"2006","journal-title":"J. Biol. Chem."},{"key":"D6BM00151C\/cit113\/1","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1038\/jid.2011.413","volume":"132","author":"Ando","year":"2012","journal-title":"J. Invest. Dermatol."},{"key":"D6BM00151C\/cit114\/1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0034-5687(82)90010-X","volume":"50","author":"Marconi","year":"1982","journal-title":"Respir. Physiol."},{"key":"D6BM00151C\/cit115\/1","first-page":"17","volume":"32","author":"Bennett","year":"2024","journal-title":"Wound Pract. Res."},{"key":"D6BM00151C\/cit116\/1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s41038-018-0128-x","volume":"6","author":"Zhao-Fleming","year":"2018","journal-title":"Burns Trauma"},{"key":"D6BM00151C\/cit117\/1","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/wrr.12049","volume":"21","author":"Volk","year":"2013","journal-title":"Wound Repair Regen."},{"key":"D6BM00151C\/cit118\/1","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.3390\/cells14231850","volume":"14","author":"Jin","year":"2025","journal-title":"Cells"},{"key":"D6BM00151C\/cit119\/1","doi-asserted-by":"crossref","first-page":"17426","DOI":"10.1038\/s41598-022-22487-4","volume":"12","author":"Jasineviciute","year":"2022","journal-title":"Sci. Rep."},{"key":"D6BM00151C\/cit120\/1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.jcis.2019.04.033","volume":"548","author":"Perro","year":"2019","journal-title":"J. Colloid Interface Sci."},{"key":"D6BM00151C\/cit121\/1","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/s41572-022-00377-3","volume":"8","author":"Falanga","year":"2022","journal-title":"Nat. Rev. Dis. Primers"},{"key":"D6BM00151C\/cit122\/1","first-page":"59","volume":"39","author":"Otero-Vinas","year":"2021","journal-title":"Surg. Technol. Int."},{"key":"D6BM00151C\/cit123\/1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/s41536-024-00359-x","volume":"9","author":"Noom","year":"2024","journal-title":"npj Regen. Med."},{"key":"D6BM00151C\/cit124\/1","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1182\/blood-2016-08-734988","volume":"129","author":"Verhoef","year":"2017","journal-title":"Blood"},{"key":"D6BM00151C\/cit125\/1","doi-asserted-by":"crossref","first-page":"44250","DOI":"10.1074\/jbc.M406261200","volume":"279","author":"Ruiz","year":"2004","journal-title":"J. Biol. Chem."},{"key":"D6BM00151C\/cit126\/1","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.2337\/diacare.15.11.1598","volume":"15","author":"Steed","year":"1992","journal-title":"Diabetes Care"},{"key":"D6BM00151C\/cit127\/1","doi-asserted-by":"crossref","first-page":"3861","DOI":"10.1007\/s00018-016-2268-0","volume":"73","author":"Land\u00e9n","year":"2016","journal-title":"Cell. Mol. Life Sci."},{"key":"D6BM00151C\/cit128\/1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.2460\/javma.248.1.43","volume":"248","author":"Bayne","year":"2016","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"D6BM00151C\/cit129\/1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S1047-2797(01)00255-1","volume":"12","author":"Margolis","year":"2002","journal-title":"Ann. Epidemiol."},{"key":"D6BM00151C\/cit130\/1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.jdin.2021.11.002","volume":"6","author":"Holmes","year":"2021","journal-title":"JAAD Int."},{"key":"D6BM00151C\/cit131\/1","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1111\/iwj.13098","volume":"16","author":"Weller","year":"2019","journal-title":"Int. Wound J."},{"key":"D6BM00151C\/cit132\/1","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1089\/ten.teb.2021.0098","volume":"28","author":"Peterson","year":"2022","journal-title":"Tissue Eng., Part B"},{"key":"D6BM00151C\/cit133\/1","doi-asserted-by":"crossref","first-page":"462","DOI":"10.4252\/wjsc.v12.i6.462","volume":"12","author":"Wang","year":"2020","journal-title":"World J. Stem Cells"},{"key":"D6BM00151C\/cit134\/1","doi-asserted-by":"crossref","first-page":"3852","DOI":"10.1016\/j.cell.2021.06.024","volume":"184","author":"Plikus","year":"2021","journal-title":"Cell"},{"key":"D6BM00151C\/cit135\/1","doi-asserted-by":"crossref","first-page":"6781","DOI":"10.2147\/JIR.S469239","volume":"17","author":"Wang","year":"2024","journal-title":"J. Inflamm. Res."},{"key":"D6BM00151C\/cit136\/1","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1186\/s40814-021-00939-4","volume":"7","author":"Alkaabi","year":"2021","journal-title":"Pilot Feasibility Stud."},{"key":"D6BM00151C\/cit137\/1","first-page":"16","volume":"L354","author":"EU","year":"2008","journal-title":"Off. J. Eur. Union"},{"key":"D6BM00151C\/cit138\/1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3389\/fcimb.2018.00008","volume":"8","author":"Varas","year":"2018","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"D6BM00151C\/cit139\/1","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0278-6915(01)00028-X","volume":"39","author":"Weiner","year":"2001","journal-title":"Food Chem. Toxicol."},{"key":"D6BM00151C\/cit140\/1","doi-asserted-by":"crossref","first-page":"494","DOI":"10.3390\/pharmaceutics15020494","volume":"15","author":"Wang","year":"2023","journal-title":"Pharmaceutics"},{"key":"D6BM00151C\/cit141\/1","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1302\/0301-620X.71B4.2768316","volume":"71","author":"Leung","year":"1989","journal-title":"J. Bone Joint Surg. Br."},{"key":"D6BM00151C\/cit142\/1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3389\/fmed.2019.00067","volume":"6","author":"Conway","year":"2019","journal-title":"Front. Med."},{"key":"D6BM00151C\/cit143\/1","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1093\/jleuko\/qiad058","volume":"114","author":"Pirttiniemi","year":"2023","journal-title":"J. Leukocyte Biol."},{"key":"D6BM00151C\/cit144\/1","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1039\/C8TB00241J","volume":"6","author":"Wang","year":"2018","journal-title":"J. Mater. Chem. B"},{"key":"D6BM00151C\/cit145\/1","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.mattod.2021.07.029","volume":"51","author":"M\u00fcller","year":"2021","journal-title":"Mater. Today"}],"container-title":["Biomaterials Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2026\/BM\/D6BM00151C","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T17:47:07Z","timestamp":1783532827000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/bm\/article\/14\/12\/3181-3199\/1234961"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":145,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2026,6,16]]}},"URL":"https:\/\/doi.org\/10.1039\/d6bm00151c","relation":{},"ISSN":["2047-4830","2047-4849"],"issn-type":[{"value":"2047-4830","type":"print"},{"value":"2047-4849","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}