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A."},{"key":"D6CB00014B\/cit121\/1","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.neuron.2011.05.036","volume":"71","author":"Kotowski","year":"2011","journal-title":"Neuron"},{"key":"D6CB00014B\/cit122\/1","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.neuron.2018.04.021","volume":"98","author":"Stoeber","year":"2018","journal-title":"Neuron"},{"key":"D6CB00014B\/cit123\/1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/s41589-023-01390-7","volume":"20","author":"Willette","year":"2024","journal-title":"Nat. Chem. Biol."},{"key":"D6CB00014B\/cit124\/1","first-page":"118","author":"Wright","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6CB00014B\/cit125\/1","doi-asserted-by":"crossref","first-page":"178311","DOI":"10.1016\/j.ejphar.2025.178311","volume":"1008","author":"Chen","year":"2025","journal-title":"Eur. J. 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Biol."},{"key":"D6CB00014B\/cit130\/1","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1096\/fj.11-195248","volume":"26","author":"Werthmann","year":"2012","journal-title":"FASEB J."},{"key":"D6CB00014B\/cit131\/1","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/s41589-023-01412-4","volume":"20","author":"Blythe","year":"2024","journal-title":"Nat. Chem. Biol."},{"key":"D6CB00014B\/cit132\/1","doi-asserted-by":"crossref","first-page":"eaal3447","DOI":"10.1126\/scitranslmed.aal3447","volume":"9","author":"Jensen","year":"2017","journal-title":"Sci. Transl. Med."},{"key":"D6CB00014B\/cit133\/1","doi-asserted-by":"crossref","first-page":"eabc5944","DOI":"10.1126\/scisignal.abc5944","volume":"14","author":"White","year":"2021","journal-title":"Sci. Signaling"},{"key":"D6CB00014B\/cit134\/1","doi-asserted-by":"publisher","DOI":"10.1101\/2025.06.12.659276","author":"Daly","year":"2025","unstructured":"C.Daly ,  A.Wright ,  R.Heukers ,  C. M.McKee ,  R. 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Pharmacol."},{"key":"D6CB00014B\/cit139\/1","doi-asserted-by":"crossref","first-page":"4877","DOI":"10.1091\/mbc.e04-02-0127","volume":"15","author":"Llad\u00f3","year":"2004","journal-title":"Mol. Biol. Cell"},{"key":"D6CB00014B\/cit140\/1","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.3390\/biom10091288","volume":"10","author":"Heckman","year":"2020","journal-title":"Biomolecules"},{"key":"D6CB00014B\/cit141\/1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3389\/fcell.2019.00127","volume":"7","author":"Phuyal","year":"2019","journal-title":"Front. Cell Dev. Biol."},{"key":"D6CB00014B\/cit142\/1","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/nature01148","volume":"420","author":"Etienne-Manneville","year":"2002","journal-title":"Nature"},{"key":"D6CB00014B\/cit143\/1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/72920","volume":"3","author":"Li","year":"2000","journal-title":"Nat. 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Chem."},{"key":"D6CB00014B\/cit149\/1","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1038\/srep02284","volume":"3","author":"Goedhart","year":"2013","journal-title":"Sci. Rep."},{"key":"D6CB00014B\/cit150\/1","doi-asserted-by":"crossref","first-page":"29201","DOI":"10.1074\/jbc.M703458200","volume":"282","author":"Rojas","year":"2007","journal-title":"J. Biol. Chem."},{"key":"D6CB00014B\/cit151\/1","doi-asserted-by":"crossref","first-page":"14693","DOI":"10.1038\/srep14693","volume":"5","author":"van Unen","year":"2015","journal-title":"Sci. Rep."},{"key":"D6CB00014B\/cit152\/1","doi-asserted-by":"crossref","first-page":"21675","DOI":"10.1038\/s41598-020-78595-6","volume":"10","author":"John Jayakumar","year":"2020","journal-title":"Sci. Rep."},{"key":"D6CB00014B\/cit153\/1","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1002\/(SICI)1096-9861(19981130)401:4<506::AID-CNE5>3.0.CO;2-#","volume":"401","author":"Lebrand","year":"1998","journal-title":"J. Comp. Neurol."},{"key":"D6CB00014B\/cit154\/1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0165-3806(99)00152-2","volume":"119","author":"Zhou","year":"2000","journal-title":"Dev. Brain Res."},{"key":"D6CB00014B\/cit155\/1","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1124\/jpet.110.170142","volume":"335","author":"Duan","year":"2010","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"D6CB00014B\/cit156\/1","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1111\/j.1476-5381.1969.tb08502.x","volume":"37","author":"Lightman","year":"1969","journal-title":"Br. J. Pharmacol."},{"key":"D6CB00014B\/cit157\/1","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1002\/glia.24219","volume":"70","author":"Benton","year":"2022","journal-title":"Glia"},{"key":"D6CB00014B\/cit158\/1","doi-asserted-by":"crossref","first-page":"e75468","DOI":"10.7554\/eLife.75468","volume":"11","author":"Puri","year":"2022","journal-title":"eLife"},{"key":"D6CB00014B\/cit159\/1","doi-asserted-by":"crossref","first-page":"116011","DOI":"10.1016\/j.celrep.2025.116011","volume":"44","author":"Lee","year":"2025","journal-title":"Cell Rep."},{"key":"D6CB00014B\/cit160\/1","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1002\/dta.422","volume":"4","author":"Barker","year":"2012","journal-title":"Drug Test. Anal."},{"key":"D6CB00014B\/cit161\/1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/00365510510013604","volume":"65","author":"K\u00e4rkk\u00e4inen","year":"2005","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"D6CB00014B\/cit162\/1","doi-asserted-by":"crossref","first-page":"9333","DOI":"10.1038\/s41598-019-45812-w","volume":"9","author":"Dean","year":"2019","journal-title":"Sci. Rep."},{"key":"D6CB00014B\/cit163\/1","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/s41598-023-27538-y","volume":"13","author":"Glynos","year":"2023","journal-title":"Sci. Rep."},{"key":"D6CB00014B\/cit164\/1","doi-asserted-by":"crossref","first-page":"1485337","DOI":"10.3389\/fpsyt.2024.1485337","volume":"15","author":"Chaves","year":"2024","journal-title":"Front. Psychiatry"},{"key":"D6CB00014B\/cit165\/1","doi-asserted-by":"crossref","first-page":"110314","DOI":"10.1016\/j.neuropharm.2025.110314","volume":"268","author":"Schimmelpfennig","year":"2025","journal-title":"Neuropharmacology"},{"key":"D6CB00014B\/cit166\/1","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1177\/02698811221104054","volume":"36","author":"Jim\u00e9nez","year":"2022","journal-title":"J. Psychopharmacol."},{"key":"D6CB00014B\/cit167\/1","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1177\/02698811251330741","volume":"39","author":"Kehler","year":"2025","journal-title":"J. Psychopharmacol."},{"key":"D6CB00014B\/cit168\/1","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1038\/s41589-025-01928-x","volume":"21","author":"Bock","year":"2025","journal-title":"Nat. Chem. Biol."},{"key":"D6CB00014B\/cit169\/1","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1038\/s41467-017-00357-2","volume":"8","author":"Godbole","year":"2017","journal-title":"Nat. Commun."},{"key":"D6CB00014B\/cit170\/1","doi-asserted-by":"crossref","first-page":"12178","DOI":"10.1038\/ncomms12178","volume":"7","author":"Namkung","year":"2016","journal-title":"Nat. Commun."},{"key":"D6CB00014B\/cit171\/1","doi-asserted-by":"crossref","first-page":"4647","DOI":"10.1091\/mbc.e11-01-0072","volume":"22","author":"Komatsu","year":"2011","journal-title":"Mol. Biol. 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Commun."},{"key":"D6CB00014B\/cit181\/1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s00213-003-1640-6","volume":"172","author":"Hasler","year":"2004","journal-title":"Psychopharmacology"},{"key":"D6CB00014B\/cit182\/1","doi-asserted-by":"crossref","first-page":"3897","DOI":"10.1097\/00001756-199812010-00024","volume":"9","author":"Vollenweider","year":"1998","journal-title":"NeuroReport"},{"key":"D6CB00014B\/cit183\/1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.biopsych.2022.08.025","volume":"93","author":"Holze","year":"2023","journal-title":"Biol. 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