{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T15:12:03Z","timestamp":1789744323721,"version":"4.0.1"},"reference-count":29,"publisher":"Royal Society of Chemistry (RSC)","license":[{"start":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:00:00Z","timestamp":1789344000000},"content-version":"vor","delay-in-days":256,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CHE2109255"],"award-info":[{"award-number":["CHE2109255"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["DGE2022168"],"award-info":[{"award-number":["DGE2022168"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011348","name":"University of Oregon","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011348","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Chem. Biol."],"abstract":"<jats:p>\n                    Aliphatic dicarboxylate Pt(\n                    <jats:sc>iv<\/jats:sc>\n                    ) compounds preserve Pt(\n                    <jats:sc>ii<\/jats:sc>\n                    ) encoded stress pathways, culminating in a Pt(\n                    <jats:sc>iv<\/jats:sc>\n                    ) compound inducing nucleolar stress at sub-nanomolar concentrations.\n                  <\/jats:p>","DOI":"10.1039\/d6cb00235h","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T06:05:16Z","timestamp":1789365916000},"update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pt(\n                    <scp>iv<\/scp>\n                    ) scaffold effects on nucleolar stress and DNA damage response pathways"],"prefix":"10.1039","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3481-2068","authenticated-orcid":false,"given":"Christopher R.","family":"Griffin","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5761-671X","authenticated-orcid":false,"given":"Victoria J.","family":"DeRose","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"issue":"35","key":"D6CB00235H\/cit1\/1","doi-asserted-by":"publisher","first-page":"8113","DOI":"10.1039\/C0DT00292E","volume":"39","author":"Wheate","year":"2010","journal-title":"Dalton Trans."},{"issue":"47","key":"D6CB00235H\/cit2\/1","doi-asserted-by":"publisher","first-page":"7265","DOI":"10.1038\/sj.onc.1206933","volume":"22","author":"Siddik","year":"2003","journal-title":"Oncogene"},{"issue":"4","key":"D6CB00235H\/cit3\/1","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1038\/nm.4291","volume":"23","author":"Bruno","year":"2017","journal-title":"Nat. Med."},{"issue":"46","key":"D6CB00235H\/cit4\/1","doi-asserted-by":"publisher","first-page":"18411","DOI":"10.1021\/jacs.9b10319","volume":"141","author":"Sutton","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"D6CB00235H\/cit5\/1","doi-asserted-by":"publisher","unstructured":"Influence of Ring Modifications on Nucleolar Stress Caused by Oxaliplatin-Like Compounds** 10.1002\/cbic.202200130","DOI":"10.1002\/cbic.202200130"},{"issue":"10","key":"D6CB00235H\/cit6\/1","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1039\/D3CB00055A","volume":"4","author":"Guerrero","year":"2023","journal-title":"RSC Chem. Biol."},{"key":"D6CB00235H\/cit7\/1","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.jinorgbio.2012.06.013","volume":"117","author":"Wexselblatt","year":"2012","journal-title":"J. Inorg. Biochem."},{"issue":"11","key":"D6CB00235H\/cit8\/1","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1016\/j.addr.2012.01.007","volume":"64","author":"Graf","year":"2012","journal-title":"Adv. Drug Delivery Rev."},{"issue":"1","key":"D6CB00235H\/cit9\/1","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1159\/000084201","volume":"68","author":"Sternberg","year":"2005","journal-title":"Oncology"},{"issue":"14","key":"D6CB00235H\/cit10\/1","doi-asserted-by":"publisher","first-page":"2188","DOI":"10.1002\/cmdc.202100115","volume":"16","author":"Gibson","year":"2021","journal-title":"ChemMedChem"},{"issue":"23","key":"D6CB00235H\/cit11\/1","doi-asserted-by":"publisher","first-page":"5554","DOI":"10.1021\/jm070740j","volume":"50","author":"Nemirovski","year":"2007","journal-title":"J. Med. Chem."},{"issue":"25","key":"D6CB00235H\/cit12\/1","doi-asserted-by":"publisher","first-page":"e202416396","DOI":"10.1002\/anie.202416396","volume":"64","author":"Chen","year":"2025","journal-title":"Angew. Chem., Int. Ed."},{"issue":"2","key":"D6CB00235H\/cit13\/1","doi-asserted-by":"publisher","first-page":"e70203","DOI":"10.1002\/ardp.70203","volume":"359","author":"Cheng","year":"2026","journal-title":"Arch. Pharm."},{"issue":"2","key":"D6CB00235H\/cit14\/1","doi-asserted-by":"publisher","first-page":"1608","DOI":"10.1021\/acs.jmedchem.4c02263","volume":"68","author":"Babu","year":"2025","journal-title":"J. Med. Chem."},{"issue":"12","key":"D6CB00235H\/cit15\/1","doi-asserted-by":"publisher","first-page":"7590","DOI":"10.1021\/acs.molpharmaceut.5c01187","volume":"22","author":"He","year":"2025","journal-title":"Mol. Pharm."},{"issue":"45","key":"D6CB00235H\/cit16\/1","doi-asserted-by":"publisher","first-page":"e202514717","DOI":"10.1002\/anie.202514717","volume":"64","author":"Sharma","year":"2025","journal-title":"Angew. Chem., Int. Ed."},{"issue":"7","key":"D6CB00235H\/cit17\/1","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1007\/s00775-010-0676-4","volume":"15","author":"Gramatica","year":"2010","journal-title":"JBIC, J. Biol. Inorg. Chem."},{"issue":"3","key":"D6CB00235H\/cit18\/1","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/S0968-0896(99)00313-2","volume":"8","author":"Ali Khan","year":"2000","journal-title":"Bioorg. Med. Chem."},{"key":"D6CB00235H\/cit19\/1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jinorgbio.2015.05.012","volume":"150","author":"Ravera","year":"2015","journal-title":"J. Inorg. Biochem."},{"key":"D6CB00235H\/cit20\/1","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.jinorgbio.2014.07.018","volume":"140","author":"Zanellato","year":"2014","journal-title":"J. Inorg. Biochem."},{"key":"D6CB00235H\/cit21\/1","doi-asserted-by":"publisher","first-page":"e9489926","DOI":"10.1155\/2021\/9489926","volume":"2021","author":"Ravera","year":"2021","journal-title":"Bioinorg. Chem. Appl."},{"issue":"10","key":"D6CB00235H\/cit22\/1","doi-asserted-by":"publisher","first-page":"2649","DOI":"10.1111\/cas.70164","volume":"116","author":"Imamura","year":"2025","journal-title":"Cancer Sci."},{"issue":"4","key":"D6CB00235H\/cit23\/1","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1021\/acschembio.3c00607","volume":"19","author":"O\u2019Dowd","year":"2024","journal-title":"ACS Chem. Biol."},{"key":"D6CB00235H\/cit24\/1","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.jbc.2021.100633","author":"Sutton","year":"2021","journal-title":"J. Biol. Chem."},{"issue":"8","key":"D6CB00235H\/cit25\/1","doi-asserted-by":"publisher","first-page":"2262","DOI":"10.1021\/acschembio.2c00399","volume":"17","author":"Pigg","year":"2022","journal-title":"ACS Chem. Biol."},{"issue":"supplement 1","key":"D6CB00235H\/cit26\/1","first-page":"1024","volume":"61","author":"Davern","year":"2020","journal-title":"J. Nucl. Med."},{"issue":"11","key":"D6CB00235H\/cit27\/1","doi-asserted-by":"publisher","first-page":"107858","DOI":"10.1016\/j.jbc.2024.107858","volume":"300","author":"Pigg","year":"2024","journal-title":"J. Biol. Chem."},{"issue":"9","key":"D6CB00235H\/cit28\/1","doi-asserted-by":"publisher","first-page":"2467","DOI":"10.1021\/cr980421n","volume":"99","author":"Jamieson","year":"1999","journal-title":"Chem. Rev."},{"issue":"7","key":"D6CB00235H\/cit29\/1","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1016\/S0039-9140(97)00017-9","volume":"44","author":"Ishiyama","year":"1997","journal-title":"Talanta"}],"container-title":["RSC Chemical Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/CB\/article-pdf\/doi\/10.1039\/D6CB00235H\/0\/D6CB00235H.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/pubs.rsc.org\/CB\/article-pdf\/doi\/10.1039\/D6CB00235H\/0\/D6CB00235H.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T14:54:21Z","timestamp":1789743261000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/CB\/article-lookup\/doi\/10.1039\/D6CB00235H"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":29,"URL":"https:\/\/doi.org\/10.1039\/d6cb00235h","relation":{},"ISSN":["2633-0679"],"issn-type":[{"value":"2633-0679","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}