{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T13:05:05Z","timestamp":1784120705977,"version":"3.55.0"},"reference-count":40,"publisher":"Royal Society of Chemistry (RSC)","issue":"27","license":[{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":182,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R35GM142869"],"award-info":[{"award-number":["R35GM142869"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Phys. Chem. Chem. Phys."],"abstract":"<jats:p>Amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), Alzheimer's disease (AD), and Parkinson's disease are associated with an abrupt aggregation of TAR DNA-binding protein 43 (TDP-43).<\/jats:p>","DOI":"10.1039\/d6cp01760f","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T09:43:24Z","timestamp":1782985404000},"page":"16459-16463","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nanoscale morphological and structural analysis of round and donut oligomers formed by C-terminal domain of TDP-43"],"prefix":"10.1039","volume":"28","author":[{"given":"Davis","family":"Pickett","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yana","family":"Purvinsh","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua T.","family":"Skrehot","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Warren","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6040-4213","authenticated-orcid":false,"given":"Dmitry","family":"Kurouski","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843, USA"},{"name":"Department of Chemistry, Texas A&M University, College Station, Texas, 77843, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"issue":"3","key":"D6CP01760F\/cit1\/1","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1016\/s0955-0674(97)80016-6","volume":"9","author":"Nakielny","year":"1997","journal-title":"Curr. Opin. Cell Biol."},{"issue":"2","key":"D6CP01760F\/cit2\/1","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1007\/s13311-015-0338-x","volume":"12","author":"Scotter","year":"2015","journal-title":"Neurotherapeutics"},{"issue":"8","key":"D6CP01760F\/cit3\/1","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1007\/s00439-016-1683-5","volume":"135","author":"Geuens","year":"2016","journal-title":"Hum. Genet."},{"issue":"4","key":"D6CP01760F\/cit4\/1","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1038\/s41582-020-0333-7","volume":"16","author":"Peng","year":"2020","journal-title":"Nat. Rev. Neurol."},{"key":"D6CP01760F\/cit5\/1","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1146\/annurev-neuro-071714-033828","volume":"38","author":"Walker","year":"2015","journal-title":"Annu. Rev. Neurosci."},{"issue":"6","key":"D6CP01760F\/cit6\/1","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1111\/bpa.12252","volume":"25","author":"Ye","year":"2015","journal-title":"Brain Pathol."},{"key":"D6CP01760F\/cit7\/1","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.mcn.2018.10.003","volume":"97","author":"Steinacker","year":"2019","journal-title":"Mol. Cell. Neurosci."},{"issue":"6","key":"D6CP01760F\/cit8\/1","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.1093\/brain\/awz099","volume":"142","author":"Nelson","year":"2019","journal-title":"Brain"},{"key":"D6CP01760F\/cit9\/1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3389\/fnmol.2020.00026","volume":"13","author":"Huang","year":"2020","journal-title":"Front. Mol. Neurosci."},{"issue":"5796","key":"D6CP01760F\/cit10\/1","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1126\/science.1134108","volume":"314","author":"Neumann","year":"2006","journal-title":"Science"},{"issue":"3","key":"D6CP01760F\/cit11\/1","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1016\/j.bbrc.2006.10.093","volume":"351","author":"Arai","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"D6CP01760F\/cit12\/1","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1002\/ana.21425","volume":"64","author":"Hasegawa","year":"2008","journal-title":"Ann. Neurol."},{"issue":"5","key":"D6CP01760F\/cit13\/1","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1128\/MCB.01279-10","volume":"31","author":"Dewey","year":"2011","journal-title":"Mol. Cell. Biol."},{"issue":"2","key":"D6CP01760F\/cit14\/1","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1074\/jbc.M110.190884","volume":"286","author":"Sephton","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"5870","key":"D6CP01760F\/cit15\/1","doi-asserted-by":"publisher","first-page":"1668","DOI":"10.1126\/science.1154584","volume":"319","author":"Sreedharan","year":"2008","journal-title":"Science"},{"issue":"30","key":"D6CP01760F\/cit16\/1","doi-asserted-by":"publisher","first-page":"20329","DOI":"10.1074\/jbc.M109.010264","volume":"284","author":"Johnson","year":"2009","journal-title":"J. Biol. Chem."},{"issue":"7","key":"D6CP01760F\/cit17\/1","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1038\/nsmb.2053","volume":"18","author":"Guo","year":"2011","journal-title":"Nat. Struct. Mol. Biol."},{"issue":"8","key":"D6CP01760F\/cit18\/1","doi-asserted-by":"publisher","first-page":"e103644","DOI":"10.1371\/journal.pone.0103644","volume":"9","author":"Sun","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"D6CP01760F\/cit19\/1","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1038\/s41593-017-0047-3","volume":"21","author":"Chou","year":"2018","journal-title":"Nat. Neurosci."},{"issue":"2","key":"D6CP01760F\/cit20\/1","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.neuron.2019.02.038","volume":"102","author":"Gasset-Rosa","year":"2019","journal-title":"Neuron"},{"issue":"7465","key":"D6CP01760F\/cit21\/1","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1038\/nature12481","volume":"501","author":"Jucker","year":"2013","journal-title":"Nature"},{"issue":"1","key":"D6CP01760F\/cit22\/1","doi-asserted-by":"publisher","first-page":"4220","DOI":"10.1038\/s41467-018-06548-9","volume":"9","author":"Porta","year":"2018","journal-title":"Nat. Commun."},{"issue":"1","key":"D6CP01760F\/cit23\/1","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1146\/annurev-anchem-071114-040435","volume":"8","author":"Centrone","year":"2015","journal-title":"Annu. Rev. Anal. Chem."},{"issue":"11","key":"D6CP01760F\/cit24\/1","doi-asserted-by":"publisher","first-page":"3315","DOI":"10.1039\/c8cs00916c","volume":"49","author":"Kurouski","year":"2020","journal-title":"Chem. Soc. Rev."},{"issue":"7","key":"D6CP01760F\/cit25\/1","doi-asserted-by":"publisher","first-page":"6612","DOI":"10.1021\/acsnano.8b01425","volume":"12","author":"Ramer","year":"2018","journal-title":"ACS Nano"},{"issue":"7","key":"D6CP01760F\/cit26\/1","doi-asserted-by":"publisher","first-page":"5146","DOI":"10.1021\/acs.chemrev.6b00448","volume":"117","author":"Dazzi","year":"2017","journal-title":"Chem. Rev."},{"key":"D6CP01760F\/cit27\/1","doi-asserted-by":"publisher","first-page":"A160","DOI":"10.1051\/0004-6361\/201833957","volume":"622","author":"Mathurin","year":"2019","journal-title":"Astron. Astrophys."},{"issue":"1","key":"D6CP01760F\/cit28\/1","doi-asserted-by":"publisher","first-page":"2945","DOI":"10.1038\/s41467-020-16728-1","volume":"11","author":"Ruggeri","year":"2020","journal-title":"Nat. Commun."},{"key":"D6CP01760F\/cit29\/1","doi-asserted-by":"publisher","first-page":"31155","DOI":"10.1038\/srep31155","volume":"6","author":"Ruggeri","year":"2016","journal-title":"Sci. Rep."},{"issue":"48","key":"D6CP01760F\/cit30\/1","doi-asserted-by":"publisher","first-page":"19650","DOI":"10.1039\/d3nr05184f","volume":"15","author":"Zhaliazka","year":"2023","journal-title":"Nanoscale"},{"issue":"10","key":"D6CP01760F\/cit31\/1","doi-asserted-by":"publisher","first-page":"6806","DOI":"10.1021\/acs.analchem.0c00593","volume":"92","author":"Zhou","year":"2020","journal-title":"Anal. Chem."},{"issue":"16","key":"D6CP01760F\/cit32\/1","doi-asserted-by":"publisher","first-page":"2380","DOI":"10.1021\/acschemneuro.2c00355","volume":"13","author":"Dou","year":"2022","journal-title":"ACS Chem. Neurosci."},{"issue":"16","key":"D6CP01760F\/cit33\/1","doi-asserted-by":"publisher","first-page":"11297","DOI":"10.1021\/acs.analchem.0c01971","volume":"92","author":"Dou","year":"2020","journal-title":"Anal. Chem."},{"key":"D6CP01760F\/cit34\/1","doi-asserted-by":"publisher","first-page":"7831","DOI":"10.1038\/ncomms8831","volume":"6","author":"Ruggeri","year":"2015","journal-title":"Nat. Commun."},{"issue":"19","key":"D6CP01760F\/cit35\/1","doi-asserted-by":"publisher","first-page":"2813","DOI":"10.1021\/acschemneuro.2c00180","volume":"13","author":"Zhaliazka","year":"2022","journal-title":"ACS Chem. Neurosci."},{"issue":"4","key":"D6CP01760F\/cit36\/1","doi-asserted-by":"publisher","first-page":"e70523","DOI":"10.1002\/pro.70523","volume":"35","author":"Warren","year":"2026","journal-title":"Protein Sci."},{"key":"D6CP01760F\/cit37\/1","doi-asserted-by":"publisher","first-page":"105350","DOI":"10.1016\/j.chemphyslip.2023.105350","volume":"257","author":"Ali","year":"2023","journal-title":"Chem. Phys. Lipids"},{"issue":"18","key":"D6CP01760F\/cit38\/1","doi-asserted-by":"publisher","first-page":"4407","DOI":"10.1021\/acs.jpclett.1c00820","volume":"12","author":"Dou","year":"2021","journal-title":"J. Phys. Chem. Lett."},{"issue":"21","key":"D6CP01760F\/cit39\/1","doi-asserted-by":"publisher","first-page":"2898","DOI":"10.1021\/acs.accounts.3c00386","volume":"56","author":"Kurouski","year":"2023","journal-title":"Acc. Chem. Res."},{"issue":"12","key":"D6CP01760F\/cit40\/1","doi-asserted-by":"publisher","first-page":"e4838","DOI":"10.1002\/pro.4838","volume":"32","author":"Rodriguez","year":"2023","journal-title":"Protein Sci."}],"container-title":["Physical Chemistry Chemical Physics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/CP\/article-pdf\/doi\/10.1039\/D6CP01760F\/0\/D6CP01760F.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T12:15:25Z","timestamp":1784117725000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/CP\/article-lookup\/doi\/10.1039\/D6CP01760F"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":40,"journal-issue":{"issue":"27","published-print":{"date-parts":[[2026,7,15]]}},"URL":"https:\/\/doi.org\/10.1039\/d6cp01760f","relation":{},"ISSN":["1463-9076","1463-9084"],"issn-type":[{"value":"1463-9076","type":"print"},{"value":"1463-9084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}