{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T22:58:43Z","timestamp":1782946723387,"version":"3.54.5"},"reference-count":136,"publisher":"Royal Society of Chemistry (RSC)","issue":"16","license":[{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"vor","delay-in-days":83,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100005010","name":"Associazione Italiana per la Ricerca sul Cancro","doi-asserted-by":"publisher","award":["AIRC IG23566"],"award-info":[{"award-number":["AIRC IG23566"]}],"id":[{"id":"10.13039\/501100005010","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Dalton Trans."],"abstract":"<jats:p>\n                    Novel heterobimetallic Pd(\n                    <jats:sc>ii<\/jats:sc>\n                    )\/Sn(\n                    <jats:sc>ii<\/jats:sc>\n                    ) complexes bearing N-heterocyclic carbene ligands exhibit pronounced cytotoxicity across cisplatin-sensitive, cisplatin-resistant, and high-grade-serous ovarian cancer cell lines.\n                  <\/jats:p>","DOI":"10.1039\/d6dt00680a","type":"journal-article","created":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T07:01:28Z","timestamp":1774422088000},"page":"6351-6372","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Insertion of SnCl\n                    <sub>2<\/sub>\n                    into the Pd\u2013Cl bond: mechanistic elucidation and antitumor evaluation of trichlorostannyl palladium\u2013NHC allyl complexes in ovarian cancer models"],"prefix":"10.1039","volume":"55","author":[{"given":"Eleonora","family":"Botter","sequence":"first","affiliation":[{"name":"Dipartimento di Scienze Molecolari e Nanosistemi, Universit\u00e0 Ca\u2019 Foscari, Campus Scientifico Via Torino 155, 30174 Venezia-Mestre, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Lauteri","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Molecolari e Nanosistemi, Universit\u00e0 Ca\u2019 Foscari, Campus Scientifico Via Torino 155, 30174 Venezia-Mestre, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5594-991X","authenticated-orcid":false,"given":"Alessandro","family":"Rubbi","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Chimiche, Universit\u00e0 degli Studi di Padova, via Marzolo 1, 35131 Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1673-5111","authenticated-orcid":false,"given":"Laura","family":"Orian","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Chimiche, Universit\u00e0 degli Studi di Padova, via Marzolo 1, 35131 Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4809-0430","authenticated-orcid":false,"given":"Matteo","family":"Forner","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze del Farmaco, Universit\u00e0 degli Studi di Padova, via Marzolo 5, 35131 Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0442-0670","authenticated-orcid":false,"given":"Valentina","family":"Gandin","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze del Farmaco, Universit\u00e0 degli Studi di Padova, via Marzolo 5, 35131 Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0288-3233","authenticated-orcid":false,"given":"Nicola","family":"Demitri","sequence":"additional","affiliation":[{"name":"Area Science Park, Elettra-Sincrotrone Trieste, S.S. 14 Km 163.5, Basovizza, 34149, Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6010-0976","authenticated-orcid":false,"given":"Vincenzo","family":"Canzonieri","sequence":"additional","affiliation":[{"name":"Pathology Unit, Centro di Riferimento Oncologico di Aviano (C.R.O.) IRCCS, via Franco Gallini 2, 33081, Aviano, Italy"},{"name":"Department of Medical, Surgical and Health Sciences, Universit\u00e0 degli Studi di Trieste, Strada di Fiume 447, Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3400-4363","authenticated-orcid":false,"given":"Flavio","family":"Rizzolio","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Molecolari e Nanosistemi, Universit\u00e0 Ca\u2019 Foscari, Campus Scientifico Via Torino 155, 30174 Venezia-Mestre, Italy"},{"name":"Pathology Unit, Centro di Riferimento Oncologico di Aviano (C.R.O.) IRCCS, via Franco Gallini 2, 33081, Aviano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Cavarzerani","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Molecolari e Nanosistemi, Universit\u00e0 Ca\u2019 Foscari, Campus Scientifico Via Torino 155, 30174 Venezia-Mestre, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9513-1182","authenticated-orcid":false,"given":"Fabiano","family":"Visentin","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Molecolari e Nanosistemi, Universit\u00e0 Ca\u2019 Foscari, Campus Scientifico Via Torino 155, 30174 Venezia-Mestre, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7345-9670","authenticated-orcid":false,"given":"Thomas","family":"Scattolin","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Chimiche, Universit\u00e0 degli Studi di Padova, via Marzolo 1, 35131 Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6DT00680A\/cit1\/1","doi-asserted-by":"crossref","first-page":"16061","DOI":"10.1038\/nrdp.2016.61","volume":"2","author":"Matulonis","year":"2016","journal-title":"Nat. Rev. Dis. Primers"},{"key":"D6DT00680A\/cit2\/1","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1126\/science.aan6733","volume":"357","author":"Le","year":"2017","journal-title":"Science"},{"key":"D6DT00680A\/cit3\/1","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1093\/annonc\/mdz135","volume":"30","author":"Matulonis","year":"2019","journal-title":"Ann. Oncol."},{"key":"D6DT00680A\/cit4\/1","doi-asserted-by":"crossref","first-page":"viii51","DOI":"10.1093\/annonc\/mdx441","volume":"28","author":"Pignata","year":"2017","journal-title":"Ann. Oncol."},{"key":"D6DT00680A\/cit5\/1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.3322\/caac.21456","volume":"68","author":"Torre","year":"2018","journal-title":"Ca-Cancer J. Clin."},{"key":"D6DT00680A\/cit6\/1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s40265-023-01834-3","volume":"83","author":"Heo","year":"2023","journal-title":"Drugs"},{"key":"D6DT00680A\/cit7\/1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.ygyno.2022.12.018","volume":"170","author":"Mauricio","year":"2023","journal-title":"Gynecol. Oncol."},{"key":"D6DT00680A\/cit8\/1","doi-asserted-by":"crossref","first-page":"100446","DOI":"10.1016\/j.xcrp.2021.100446","volume":"2","author":"Scattolin","year":"2021","journal-title":"Cell Rep. Phys. Sci."},{"key":"D6DT00680A\/cit9\/1","doi-asserted-by":"crossref","first-page":"484","DOI":"10.2174\/187152007781668661","volume":"7","author":"Caires","year":"2007","journal-title":"Anticancer Agents Med. Chem."},{"key":"D6DT00680A\/cit10\/1","doi-asserted-by":"crossref","first-page":"11935","DOI":"10.1002\/anie.201602814","volume":"55","author":"Fong","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"key":"D6DT00680A\/cit11\/1","doi-asserted-by":"crossref","first-page":"4751","DOI":"10.1039\/C4CS00063C","volume":"43","author":"Kapdi","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"D6DT00680A\/cit12\/1","doi-asserted-by":"crossref","first-page":"10383","DOI":"10.1021\/jacs.0c01369","volume":"142","author":"Zhou","year":"2020","journal-title":"J. Am. Chem. Soc."},{"key":"D6DT00680A\/cit13\/1","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.molstruc.2019.03.020","volume":"1186","author":"Fiori-Duarte","year":"2019","journal-title":"J. Mol. Struct."},{"key":"D6DT00680A\/cit14\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jinorgbio.2016.09.016","volume":"165","author":"Massai","year":"2016","journal-title":"J. Inorg. Biochem."},{"key":"D6DT00680A\/cit15\/1","doi-asserted-by":"crossref","first-page":"26680","DOI":"10.1039\/D2RA05332B","volume":"12","author":"Massai","year":"2022","journal-title":"RSC Adv."},{"key":"D6DT00680A\/cit16\/1","doi-asserted-by":"crossref","first-page":"e5839","DOI":"10.1002\/aoc.5839","volume":"34","author":"Lighvan","year":"2020","journal-title":"Appl. Organomet. Chem."},{"key":"D6DT00680A\/cit17\/1","doi-asserted-by":"crossref","first-page":"e3740","DOI":"10.1002\/aoc.3740","volume":"31","author":"Karami","year":"2017","journal-title":"Appl. Organomet. Chem."},{"key":"D6DT00680A\/cit18\/1","doi-asserted-by":"crossref","first-page":"8463","DOI":"10.1039\/D4DT00919C","volume":"53","author":"Tonon","year":"2024","journal-title":"Dalton Trans."},{"key":"D6DT00680A\/cit19\/1","doi-asserted-by":"crossref","first-page":"e202400822","DOI":"10.1002\/ejic.202400822","volume":"28","author":"Bru","year":"2025","journal-title":"Eur. J. Inorg. Chem."},{"key":"D6DT00680A\/cit20\/1","doi-asserted-by":"crossref","first-page":"110857","DOI":"10.1016\/j.jinorgbio.2019.110857","volume":"202","author":"Wei","year":"2020","journal-title":"J. Inorg. Biochem."},{"key":"D6DT00680A\/cit21\/1","doi-asserted-by":"crossref","first-page":"11397","DOI":"10.1039\/C8DT02389A","volume":"47","author":"Icsel","year":"2018","journal-title":"Dalton Trans."},{"key":"D6DT00680A\/cit22\/1","doi-asserted-by":"crossref","first-page":"11868","DOI":"10.1002\/chem.202002199","volume":"26","author":"Scattolin","year":"2020","journal-title":"Chem. \u2013 Eur. J."},{"key":"D6DT00680A\/cit23\/1","doi-asserted-by":"crossref","first-page":"14414","DOI":"10.1021\/acs.jmedchem.4c01203","volume":"67","author":"Bortolamiol","year":"2024","journal-title":"J. Med. Chem."},{"key":"D6DT00680A\/cit24\/1","doi-asserted-by":"crossref","first-page":"11135","DOI":"10.1039\/D2DT01821G","volume":"51","author":"Bortolamiol","year":"2022","journal-title":"Dalton Trans."},{"key":"D6DT00680A\/cit25\/1","doi-asserted-by":"crossref","first-page":"12238","DOI":"10.1039\/D0CC03883K","volume":"56","author":"Scattolin","year":"2020","journal-title":"Chem. Commun."},{"key":"D6DT00680A\/cit26\/1","doi-asserted-by":"crossref","first-page":"2592","DOI":"10.1039\/D5MD00039D","volume":"16","author":"Donati","year":"2025","journal-title":"RSC Med. Chem."},{"key":"D6DT00680A\/cit27\/1","doi-asserted-by":"crossref","first-page":"e202200103","DOI":"10.1002\/ejic.202200103","volume":"2022","author":"Scattolin","year":"2022","journal-title":"Eur. J. Inorg. Chem."},{"key":"D6DT00680A\/cit28\/1","doi-asserted-by":"crossref","first-page":"e5876","DOI":"10.1002\/aoc.5876","volume":"34","author":"Scattolin","year":"2020","journal-title":"Appl. Organomet. Chem."},{"key":"D6DT00680A\/cit29\/1","doi-asserted-by":"crossref","first-page":"11720","DOI":"10.1039\/D5DT01326G","volume":"54","author":"Saito","year":"2025","journal-title":"Dalton Trans."},{"key":"D6DT00680A\/cit30\/1","doi-asserted-by":"crossref","first-page":"e4902","DOI":"10.1002\/aoc.4902","volume":"33","author":"Scattolin","year":"2019","journal-title":"Appl. Organomet. Chem."},{"key":"D6DT00680A\/cit31\/1","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.ejmech.2019.06.065","volume":"179","author":"Scattolin","year":"2019","journal-title":"Eur. J. Med. Chem."},{"key":"D6DT00680A\/cit32\/1","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1146\/annurev-pharmtox-052220-102509","volume":"62","author":"Gencheva","year":"2022","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"D6DT00680A\/cit33\/1","doi-asserted-by":"crossref","first-page":"10175","DOI":"10.1002\/chem.201905792","volume":"26","author":"Ghareeb","year":"2020","journal-title":"Chem. \u2013 Eur. J."},{"key":"D6DT00680A\/cit34\/1","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1021\/acs.organomet.3c00514","volume":"43","author":"Madabeni","year":"2024","journal-title":"Organometallics"},{"key":"D6DT00680A\/cit35\/1","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1021\/ja00782a080","volume":"95","author":"Trost","year":"1973","journal-title":"J. Am. Chem. Soc."},{"key":"D6DT00680A\/cit36\/1","doi-asserted-by":"crossref","first-page":"7976","DOI":"10.1039\/D0NJ01336F","volume":"44","author":"Tsipis","year":"2020","journal-title":"New J. Chem."},{"key":"D6DT00680A\/cit37\/1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0022-328X(00)84779-8","volume":"26","author":"Crosby","year":"1971","journal-title":"J. Organomet. Chem."},{"key":"D6DT00680A\/cit38\/1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0073-8085(70)80010-9","volume":"4","author":"Belluco","year":"1970","journal-title":"Inorg. Chim. Acta, Rev."},{"key":"D6DT00680A\/cit39\/1","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.1021\/ic00188a038","volume":"23","author":"Albinati","year":"1984","journal-title":"Inorg. Chem."},{"key":"D6DT00680A\/cit40\/1","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1021\/om00100a008","volume":"7","author":"Musco","year":"1988","journal-title":"Organometallics"},{"key":"D6DT00680A\/cit41\/1","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1039\/DT9890000615","author":"Grassi","year":"1989","journal-title":"J. Chem. Soc., Dalton Trans."},{"key":"D6DT00680A\/cit42\/1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1039\/DT9900000251","author":"Grassi","year":"1990","journal-title":"J. Chem. Soc., Dalton Trans."},{"key":"D6DT00680A\/cit43\/1","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1007\/BF00619011","volume":"10","author":"Garc\u00eda","year":"1985","journal-title":"Transition Met. Chem."},{"key":"D6DT00680A\/cit44\/1","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1039\/DT9910000859","author":"Bott","year":"1991","journal-title":"J. Chem. Soc., Dalton Trans."},{"key":"D6DT00680A\/cit45\/1","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1039\/DT9920002389","author":"Pinillos","year":"1992","journal-title":"J. Chem. Soc., Dalton Trans."},{"key":"D6DT00680A\/cit46\/1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jorganchem.2014.06.011","volume":"768","author":"Maity","year":"2014","journal-title":"J. Organomet. Chem."},{"key":"D6DT00680A\/cit47\/1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0020-1693(00)89148-3","volume":"61","author":"Kretschmer","year":"1982","journal-title":"Inorg. Chim. Acta"},{"key":"D6DT00680A\/cit48\/1","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.jorganchem.2009.10.033","volume":"695","author":"Therrien","year":"2010","journal-title":"J. Organomet. Chem."},{"key":"D6DT00680A\/cit49\/1","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1002\/ejic.201700098","volume":"2017","author":"Nov\u00e1k","year":"2017","journal-title":"Eur. J. Inorg. Chem."},{"key":"D6DT00680A\/cit50\/1","doi-asserted-by":"crossref","first-page":"44","DOI":"10.3390\/inorganics5030044","volume":"5","author":"Renier","year":"2017","journal-title":"Inorganics"},{"key":"D6DT00680A\/cit51\/1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jorganchem.2018.08.017","volume":"874","author":"\u00c1lvarez-Pazos","year":"2018","journal-title":"J. Organomet. Chem."},{"key":"D6DT00680A\/cit52\/1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jorganchem.2019.04.002","volume":"891","author":"Berg","year":"2019","journal-title":"J. Organomet. Chem."},{"key":"D6DT00680A\/cit53\/1","doi-asserted-by":"crossref","first-page":"3808","DOI":"10.1021\/om1004308","volume":"29","author":"Albertin","year":"2010","journal-title":"Organometallics"},{"key":"D6DT00680A\/cit54\/1","doi-asserted-by":"crossref","first-page":"19252","DOI":"10.1021\/acsomega.1c02665","volume":"6","author":"Nabiyeva","year":"2021","journal-title":"ACS Omega"},{"key":"D6DT00680A\/cit55\/1","doi-asserted-by":"crossref","first-page":"122891","DOI":"10.1016\/j.jorganchem.2023.122891","volume":"1001","author":"Lati\u015f","year":"2023","journal-title":"J. Organomet. Chem."},{"key":"D6DT00680A\/cit56\/1","doi-asserted-by":"crossref","first-page":"657599","DOI":"10.3389\/fchem.2021.657599","volume":"9","author":"Syed Annuar","year":"2021","journal-title":"Front. Chem."},{"key":"D6DT00680A\/cit57\/1","doi-asserted-by":"crossref","first-page":"10909","DOI":"10.1039\/D1DT01272J","volume":"50","author":"Wu","year":"2021","journal-title":"Dalton Trans."},{"key":"D6DT00680A\/cit58\/1","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/BF00391500","volume":"114","author":"K\u00f6pf-Maier","year":"1988","journal-title":"J. Cancer Res. Clin. Oncol."},{"key":"D6DT00680A\/cit59\/1","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1080\/00958970600763631","volume":"60","author":"Momeni","year":"2007","journal-title":"J. Coord. Chem."},{"key":"D6DT00680A\/cit60\/1","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1021\/om0207414","volume":"22","author":"Thoonen","year":"2003","journal-title":"Organometallics"},{"key":"D6DT00680A\/cit61\/1","doi-asserted-by":"crossref","first-page":"C33","DOI":"10.1016\/0022-328X(92)80082-9","volume":"427","author":"Alvarez","year":"1992","journal-title":"J. Organomet. Chem."},{"key":"D6DT00680A\/cit62\/1","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1023\/A:1026064708867","volume":"28","author":"Noskowska","year":"2003","journal-title":"Transition Met. Chem."},{"key":"D6DT00680A\/cit63\/1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0020-1693(00)87776-2","volume":"133","author":"Gianotti","year":"1987","journal-title":"Inorg. Chim. Acta"},{"key":"D6DT00680A\/cit64\/1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0020-1693(94)03890-2","volume":"222","author":"Hirako","year":"1994","journal-title":"Inorg. Chim. Acta"},{"key":"D6DT00680A\/cit65\/1","doi-asserted-by":"crossref","first-page":"3432","DOI":"10.1002\/ejic.201900375","volume":"2019","author":"Van Niekerk","year":"2019","journal-title":"Eur. J. Inorg. Chem."},{"key":"D6DT00680A\/cit66\/1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1039\/9781788016452-00143","volume-title":"Metal-based Anticancer Agents","author":"Curado","year":"2019","unstructured":"N.Curado  and  M.Contel , in  Metal-based Anticancer Agents , ed.  A. Casini ,  A. Vessi\u00e8res  and  S. M. Meier-Menches ,  The Royal Society of Chemistry ,  2019 , pp.  143\u2013168"},{"key":"D6DT00680A\/cit67\/1","doi-asserted-by":"crossref","first-page":"15291","DOI":"10.1039\/D4SC04585H","volume":"15","author":"Dietl","year":"2024","journal-title":"Chem. Sci."},{"key":"D6DT00680A\/cit68\/1","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1021\/acs.organomet.3c00299","volume":"42","author":"Scattolin","year":"2023","journal-title":"Organometallics"},{"key":"D6DT00680A\/cit69\/1","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1039\/C0DT00811G","volume":"40","author":"Canovese","year":"2011","journal-title":"Dalton Trans."},{"key":"D6DT00680A\/cit70\/1","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1021\/om970115k","volume":"16","author":"Sakaki","year":"1997","journal-title":"Organometallics"},{"key":"D6DT00680A\/cit71\/1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0020-1693(97)06155-0","volume":"277","author":"Canovese","year":"1998","journal-title":"Inorg. Chim. Acta"},{"key":"D6DT00680A\/cit72\/1","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1021\/om980893s","volume":"18","author":"Abrams","year":"1999","journal-title":"Organometallics"},{"key":"D6DT00680A\/cit73\/1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0022-328X(00)86025-8","volume":"217","author":"Benn","year":"1981","journal-title":"J. Organomet. Chem."},{"key":"D6DT00680A\/cit74\/1","doi-asserted-by":"crossref","first-page":"7979","DOI":"10.1021\/jacs.8b04073","volume":"140","author":"Wang","year":"2018","journal-title":"J. Am. Chem. Soc."},{"key":"D6DT00680A\/cit75\/1","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1021\/acs.organomet.3c00177","volume":"42","author":"Nayak","year":"2023","journal-title":"Organometallics"},{"key":"D6DT00680A\/cit76\/1","doi-asserted-by":"crossref","first-page":"4101","DOI":"10.1021\/ja057704z","volume":"128","author":"Marion","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"D6DT00680A\/cit77\/1","doi-asserted-by":"crossref","first-page":"13616","DOI":"10.1039\/C8DT01831F","volume":"47","author":"Scattolin","year":"2018","journal-title":"Dalton Trans."},{"key":"D6DT00680A\/cit78\/1","doi-asserted-by":"crossref","first-page":"115381","DOI":"10.1016\/j.poly.2021.115381","volume":"207","author":"Scattolin","year":"2021","journal-title":"Polyhedron"},{"key":"D6DT00680A\/cit79\/1","doi-asserted-by":"crossref","first-page":"122014","DOI":"10.1016\/j.jorganchem.2021.122014","volume":"952","author":"Scattolin","year":"2021","journal-title":"J. Organomet. Chem."},{"key":"D6DT00680A\/cit80\/1","doi-asserted-by":"crossref","first-page":"120857","DOI":"10.1016\/j.jorganchem.2019.07.008","volume":"899","author":"Scattolin","year":"2019","journal-title":"J. Organomet. Chem."},{"key":"D6DT00680A\/cit81\/1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s13402-024-00960-8","volume":"48","author":"Kalla","year":"2025","journal-title":"Cell. Oncol."},{"key":"D6DT00680A\/cit82\/1","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1038\/s41591-019-0422-6","volume":"25","author":"Kopper","year":"2019","journal-title":"Nat. Med."},{"key":"D6DT00680A\/cit83\/1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3390\/cancers15010139","volume":"15","author":"Idrisova","year":"2023","journal-title":"Cancers"},{"key":"D6DT00680A\/cit84\/1","first-page":"319","volume":"19","author":"Yang","year":"2022","journal-title":"Cancer Biol. Med."},{"key":"D6DT00680A\/cit85\/1","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1038\/s43018-020-0102-y","volume":"1","author":"Lo","year":"2020","journal-title":"Nat. Cancer"},{"key":"D6DT00680A\/cit86\/1","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1146\/annurev-pharmtox-010818-021108","volume":"59","author":"Takahashi","year":"2019","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"D6DT00680A\/cit87\/1","doi-asserted-by":"crossref","first-page":"12888","DOI":"10.1039\/D0SC04082G","volume":"11","author":"Anthony","year":"2020","journal-title":"Chem. Sci."},{"key":"D6DT00680A\/cit88\/1","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1073\/pnas.241655498","volume":"99","author":"Ott","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6DT00680A\/cit89\/1","doi-asserted-by":"crossref","first-page":"e36","DOI":"10.1093\/nar\/gkl1169","volume":"35","author":"Ismail","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"D6DT00680A\/cit90\/1","doi-asserted-by":"crossref","first-page":"2828","DOI":"10.1128\/MCB.01830-08","volume":"29","author":"Fragkos","year":"2009","journal-title":"Mol. Cell. Biol."},{"key":"D6DT00680A\/cit91\/1","doi-asserted-by":"crossref","first-page":"8351","DOI":"10.1021\/jo101589h","volume":"75","author":"Williams","year":"2010","journal-title":"J. Org. Chem."},{"key":"D6DT00680A\/cit92\/1","doi-asserted-by":"crossref","first-page":"e6624","DOI":"10.1002\/aoc.6624","volume":"38","author":"Scattolin","year":"2024","journal-title":"Appl. Organomet. Chem."},{"key":"D6DT00680A\/cit93\/1","doi-asserted-by":"crossref","first-page":"17240","DOI":"10.1039\/C4DT02747G","volume":"43","author":"Cesari","year":"2014","journal-title":"Dalton Trans."},{"key":"D6DT00680A\/cit94\/1","doi-asserted-by":"crossref","first-page":"4063","DOI":"10.1021\/om300340w","volume":"31","author":"Su","year":"2012","journal-title":"Organometallics"},{"key":"D6DT00680A\/cit95\/1","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1107\/S1600577525001055","volume":"32","author":"Hegde","year":"2025","journal-title":"J. Synchrotron Radiat."},{"key":"D6DT00680A\/cit96\/1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1107\/S0907444909047337","volume":"66","author":"Kabsch","year":"2010","journal-title":"Acta Crystallogr., Sect. D: Biol. Crystallogr."},{"key":"D6DT00680A\/cit97\/1","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1107\/S0907444910045749","volume":"67","author":"Winn","year":"2011","journal-title":"Acta Crystallogr., Sect. D: Biol. Crystallogr."},{"key":"D6DT00680A\/cit98\/1","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1107\/S0907444913000061","volume":"69","author":"Evans","year":"2013","journal-title":"Acta Crystallogr., Sect. D: Biol. Crystallogr."},{"key":"D6DT00680A\/cit99\/1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1107\/S2053273314026370","volume":"71","author":"Sheldrick","year":"2015","journal-title":"Acta Crystallogr., Sect. A: Found. Adv."},{"key":"D6DT00680A\/cit100\/1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1107\/S2053229614024218","volume":"71","author":"Sheldrick","year":"2015","journal-title":"Acta Crystallogr., Sect. C"},{"key":"D6DT00680A\/cit101\/1","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1107\/S0907444910007493","volume":"66","author":"Emsley","year":"2010","journal-title":"Acta Crystallogr., Sect. D: Biol. Crystallogr."},{"key":"D6DT00680A\/cit102\/1","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1107\/S0021889812029111","volume":"45","author":"Farrugia","year":"2012","journal-title":"J. Appl. Crystallogr."},{"key":"D6DT00680A\/cit103\/1","unstructured":"PyMOL | pymol.org,  https:\/\/www.pymol.org\/ , (accessed 12 December 2025)"},{"key":"D6DT00680A\/cit104\/1","doi-asserted-by":"crossref","first-page":"162501","DOI":"10.1063\/5.0258496","volume":"162","author":"Baerends","year":"2025","journal-title":"J. Chem. Phys."},{"key":"D6DT00680A\/cit105\/1","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0009-2614(92)85807-M","volume":"197","author":"Gill","year":"1992","journal-title":"Chem. Phys. Lett."},{"key":"D6DT00680A\/cit106\/1","first-page":"211","volume":"1","author":"Grimme","year":"2011","journal-title":"Wiley Interdiscip. Rev.: Comput. Mol. Sci."},{"key":"D6DT00680A\/cit107\/1","doi-asserted-by":"crossref","first-page":"154104","DOI":"10.1063\/1.3382344","volume":"132","author":"Grimme","year":"2010","journal-title":"J. Chem. Phys."},{"key":"D6DT00680A\/cit108\/1","doi-asserted-by":"crossref","first-page":"154104","DOI":"10.1063\/1.1884601","volume":"122","author":"Becke","year":"2005","journal-title":"J. Chem. Phys."},{"key":"D6DT00680A\/cit109\/1","doi-asserted-by":"crossref","first-page":"154101","DOI":"10.1063\/1.2065267","volume":"123","author":"Becke","year":"2005","journal-title":"J. Chem. Phys."},{"key":"D6DT00680A\/cit110\/1","doi-asserted-by":"crossref","first-page":"024101","DOI":"10.1063\/1.1949201","volume":"123","author":"Johnson","year":"2005","journal-title":"J. Chem. Phys."},{"key":"D6DT00680A\/cit111\/1","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1002\/jcc.21759","volume":"32","author":"Grimme","year":"2011","journal-title":"J. Comput. Chem."},{"key":"D6DT00680A\/cit112\/1","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1002\/jcc.10255","volume":"24","author":"Van Lenthe","year":"2003","journal-title":"J. Comput. Chem."},{"key":"D6DT00680A\/cit113\/1","doi-asserted-by":"crossref","first-page":"4597","DOI":"10.1063\/1.466059","volume":"99","author":"Lenthe","year":"1993","journal-title":"J. Chem. Phys."},{"key":"D6DT00680A\/cit114\/1","doi-asserted-by":"crossref","first-page":"9783","DOI":"10.1063\/1.467943","volume":"101","author":"Van Lenthe","year":"1994","journal-title":"J. Chem. Phys."},{"key":"D6DT00680A\/cit115\/1","doi-asserted-by":"crossref","first-page":"8943","DOI":"10.1063\/1.478813","volume":"110","author":"Van Lenthe","year":"1999","journal-title":"J. Chem. Phys."},{"key":"D6DT00680A\/cit116\/1","doi-asserted-by":"crossref","first-page":"27592","DOI":"10.1039\/C8CP05922E","volume":"20","author":"Bortoli","year":"2018","journal-title":"Phys. Chem. Chem. Phys."},{"key":"D6DT00680A\/cit117\/1","doi-asserted-by":"crossref","first-page":"4646","DOI":"10.1021\/acs.inorgchem.0c03619","volume":"60","author":"Madabeni","year":"2021","journal-title":"Inorg. Chem."},{"key":"D6DT00680A\/cit118\/1","doi-asserted-by":"crossref","first-page":"17288","DOI":"10.1021\/acs.inorgchem.3c02568","volume":"62","author":"Zeppilli","year":"2023","journal-title":"Inorg. Chem."},{"key":"D6DT00680A\/cit119\/1","doi-asserted-by":"crossref","first-page":"12126","DOI":"10.1039\/D4SC03329A","volume":"15","author":"Madabeni","year":"2024","journal-title":"Chem. Sci."},{"key":"D6DT00680A\/cit120\/1","doi-asserted-by":"crossref","first-page":"10022","DOI":"10.1021\/acs.inorgchem.5c00581","volume":"64","author":"Rubbi","year":"2025","journal-title":"Inorg. Chem."},{"key":"D6DT00680A\/cit121\/1","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/s002140050457","volume":"101","author":"Pye","year":"1999","journal-title":"Theor. Chem. Acc."},{"key":"D6DT00680A\/cit122\/1","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1063\/1.454603","volume":"88","author":"Versluis","year":"1988","journal-title":"J. Chem. Phys."},{"key":"D6DT00680A\/cit123\/1","doi-asserted-by":"crossref","first-page":"10890","DOI":"10.1021\/ja00053a027","volume":"114","author":"Fan","year":"1992","journal-title":"J. Am. Chem. Soc."},{"key":"D6DT00680A\/cit124\/1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0010-4655(96)00120-8","volume":"100","author":"B\u00e9rces","year":"1997","journal-title":"Comput. Phys. Commun."},{"key":"D6DT00680A\/cit125\/1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0010-4655(96)00119-1","volume":"100","author":"Jacobsen","year":"1997","journal-title":"Comput. Phys. Commun."},{"key":"D6DT00680A\/cit126\/1","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1002\/qua.20653","volume":"104","author":"Wolff","year":"2005","journal-title":"Int. J. Quantum Chem."},{"key":"D6DT00680A\/cit127\/1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00214-007-0310-x","volume":"120","author":"Zhao","year":"2008","journal-title":"Theor. Chem. Acc."},{"key":"D6DT00680A\/cit128\/1","doi-asserted-by":"crossref","first-page":"4192","DOI":"10.1021\/acsomega.8b03668","volume":"4","author":"Monticelli","year":"2019","journal-title":"ACS Omega"},{"key":"D6DT00680A\/cit129\/1","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1007\/s10637-010-9466-7","volume":"29","author":"Zanella","year":"2011","journal-title":"Invest. New Drugs"},{"key":"D6DT00680A\/cit130\/1","doi-asserted-by":"crossref","first-page":"116697","DOI":"10.1016\/j.ejmech.2024.116697","volume":"276","author":"Miglioli","year":"2024","journal-title":"Eur. J. Med. Chem."},{"key":"D6DT00680A\/cit131a\/1","doi-asserted-by":"publisher","year":"2026","unstructured":"CCDC 2512443: Experimental Crystal Structure Determination ,  2026 ,  10.5517\/ccdc.csd.cc2qbdk1","DOI":"10.5517\/ccdc.csd.cc2qbdk1"},{"key":"D6DT00680A\/cit131b\/1","doi-asserted-by":"publisher","year":"2026","unstructured":"CCDC 2512444: Experimental Crystal Structure Determination ,  2026 ,  10.5517\/ccdc.csd.cc2qbdl2","DOI":"10.5517\/ccdc.csd.cc2qbdl2"},{"key":"D6DT00680A\/cit131c\/1","doi-asserted-by":"publisher","year":"2026","unstructured":"CCDC 2512445: Experimental Crystal Structure Determination ,  2026 ,  10.5517\/ccdc.csd.cc2qbdm3","DOI":"10.5517\/ccdc.csd.cc2qbdm3"},{"key":"D6DT00680A\/cit131d\/1","doi-asserted-by":"publisher","year":"2026","unstructured":"CCDC 2512446: Experimental Crystal Structure Determination ,  2026 ,  10.5517\/ccdc.csd.cc2qbdn4","DOI":"10.5517\/ccdc.csd.cc2qbdn4"},{"key":"D6DT00680A\/cit131e\/1","doi-asserted-by":"publisher","year":"2026","unstructured":"CCDC 2512447: Experimental Crystal Structure Determination ,  2026 ,  10.5517\/ccdc.csd.cc2qbdp5","DOI":"10.5517\/ccdc.csd.cc2qbdp5"},{"key":"D6DT00680A\/cit131f\/1","doi-asserted-by":"publisher","year":"2026","unstructured":"CCDC 2512448: Experimental Crystal Structure Determination ,  2026 ,  10.5517\/ccdc.csd.cc2qbdq6","DOI":"10.5517\/ccdc.csd.cc2qbdq6"}],"container-title":["Dalton Transactions"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2026\/DT\/D6DT00680A","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:55:21Z","timestamp":1782942921000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.rsc.org\/dt\/article\/55\/16\/6351-6372\/1228695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":136,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2026,4,28]]}},"URL":"https:\/\/doi.org\/10.1039\/d6dt00680a","relation":{},"ISSN":["1477-9226","1477-9234"],"issn-type":[{"value":"1477-9226","type":"print"},{"value":"1477-9234","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}