{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T23:54:40Z","timestamp":1790034880481,"version":"4.0.1"},"reference-count":50,"publisher":"Royal Society of Chemistry (RSC)","issue":"14","license":[{"start":{"date-parts":[[2027,6,26]],"date-time":"2027-06-26T00:00:00Z","timestamp":1813968000000},"content-version":"am","delay-in-days":541,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    SAOS ameliorated scopolamine-induced memory deficits in mice and rats by enhancing acetylcholine, alleviating oxidative stress, restoring\n                    <jats:italic>Roseburia<\/jats:italic>\n                    , and reversing reductions in serum\n                    <jats:italic>N-<\/jats:italic>\n                    arachidonoyl dopamine and cortical linoleoyl ethanolamide.\n                  <\/jats:p>","DOI":"10.1039\/d6fo01790h","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T12:54:16Z","timestamp":1782478456000},"page":"6391-6404","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Saturated alginate oligosaccharide as a new functional food: preparation, characterization and alleviation of cognitive impairment through pre-intervention"],"prefix":"10.1039","volume":"17","author":[{"given":"Youjing","family":"Lv","sequence":"first","affiliation":[{"name":"Shandong Key Laboratory of Glycoscience and Glycotherapeutics, Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China"},{"name":"Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Shao","sequence":"additional","affiliation":[{"name":"Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiliang","family":"Fu","sequence":"additional","affiliation":[{"name":"Shandong Key Laboratory of Glycoscience and Glycotherapeutics, Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China"},{"name":"Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Depeng","family":"Lv","sequence":"additional","affiliation":[{"name":"Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingsen","family":"Shang","sequence":"additional","affiliation":[{"name":"Shandong Key Laboratory of Glycoscience and Glycotherapeutics, Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China"},{"name":"Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Yang","sequence":"additional","affiliation":[{"name":"Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunlei","family":"Wang","sequence":"additional","affiliation":[{"name":"Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Guo","sequence":"additional","affiliation":[{"name":"Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Lin","sequence":"additional","affiliation":[{"name":"Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Zhao","sequence":"additional","affiliation":[{"name":"Shandong Key Laboratory of Glycoscience and Glycotherapeutics, Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangli","family":"Yu","sequence":"additional","affiliation":[{"name":"Shandong Key Laboratory of Glycoscience and Glycotherapeutics, Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8545-8384","authenticated-orcid":false,"given":"Quancai","family":"Li","sequence":"additional","affiliation":[{"name":"Shandong Key Laboratory of Glycoscience and Glycotherapeutics, Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China"},{"name":"Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6FO01790H\/cit1\/1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s41398-023-02361-1","volume":"13","author":"Chen","year":"2022","journal-title":"Transl. Psychiatry"},{"key":"D6FO01790H\/cit2\/1","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/joim.13244","volume":"290","author":"Liss","year":"2021","journal-title":"J. Intern. Med."},{"key":"D6FO01790H\/cit3\/1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/s41398-020-0690-4","volume":"10","author":"Yao","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"D6FO01790H\/cit4\/1","doi-asserted-by":"crossref","first-page":"101777","DOI":"10.1016\/j.arr.2022.101777","volume":"82","author":"Coley","year":"2022","journal-title":"Ageing Res. Rev."},{"key":"D6FO01790H\/cit5\/1","first-page":"9420061","volume":"2","author":"Zhang","year":"2025","journal-title":"Food Sci. Hum. Wellness"},{"key":"D6FO01790H\/cit6\/1","doi-asserted-by":"crossref","first-page":"135632","DOI":"10.1016\/j.ijbiomac.2024.135632","volume":"280","author":"Anjana","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D6FO01790H\/cit7\/1","first-page":"271","volume":"5","author":"Haug","year":"1966","journal-title":"Acta Chem. Scand."},{"key":"D6FO01790H\/cit8\/1","first-page":"309","volume":"93","author":"Wylie","year":"1973","journal-title":"R. Soc. Health J."},{"key":"D6FO01790H\/cit9\/1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1080\/10408398.2021.1946008","volume":"63","author":"Zhang","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"D6FO01790H\/cit10\/1","doi-asserted-by":"crossref","first-page":"7703","DOI":"10.1080\/10408398.2021.1916736","volume":"62","author":"Xie","year":"2022","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"D6FO01790H\/cit11\/1","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.nutres.2006.09.015","volume":"26","author":"Wang","year":"2006","journal-title":"Nutr. Res."},{"key":"D6FO01790H\/cit12\/1","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.3390\/nu17091424","volume":"17","author":"Li","year":"2025","journal-title":"Nutrients"},{"key":"D6FO01790H\/cit13\/1","doi-asserted-by":"crossref","first-page":"2935","DOI":"10.1021\/acs.jafc.4c10378","volume":"73","author":"Lu","year":"2025","journal-title":"J. Agric. Food Chem."},{"key":"D6FO01790H\/cit14\/1","doi-asserted-by":"crossref","first-page":"117124","DOI":"10.1016\/j.carbpol.2020.117124","volume":"251","author":"Bi","year":"2021","journal-title":"Carbohydr. Polym."},{"key":"D6FO01790H\/cit15\/1","doi-asserted-by":"crossref","first-page":"5828","DOI":"10.3390\/md13095828","volume":"13","author":"Zhou","year":"2015","journal-title":"Mar. Drugs"},{"key":"D6FO01790H\/cit16\/1","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s40265-020-01268-1","volume":"80","author":"Syed","year":"2020","journal-title":"Drugs"},{"key":"D6FO01790H\/cit17\/1","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s13195-020-00678-3","volume":"12","author":"Wang","year":"2020","journal-title":"Alzheimers Res. Ther."},{"key":"D6FO01790H\/cit18\/1","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s13195-021-00795-7","volume":"13","author":"Xiao","year":"2021","journal-title":"Alzheimers. Res. Ther."},{"key":"D6FO01790H\/cit19\/1","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/s41422-019-0216-x","volume":"29","author":"Wang","year":"2019","journal-title":"Cell Res."},{"key":"D6FO01790H\/cit20\/1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s13024-023-00700-w","volume":"19","author":"Bosch","year":"2024","journal-title":"Mol. Neurodegener."},{"key":"D6FO01790H\/cit21\/1","doi-asserted-by":"crossref","first-page":"10130","DOI":"10.1080\/10408398.2022.2067832","volume":"63","author":"Bi","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"D6FO01790H\/cit22\/1","doi-asserted-by":"crossref","first-page":"109424","DOI":"10.1016\/j.carres.2025.109424","volume":"551","author":"Shao","year":"2025","journal-title":"Carbohydr. Res."},{"key":"D6FO01790H\/cit23\/1","first-page":"648","volume":"37","author":"Wang","year":"2009","journal-title":"Chin. J. Anal. Chem."},{"key":"D6FO01790H\/cit24\/1","first-page":"e1821","volume":"6","author":"Eagle","year":"2016","journal-title":"Bio. Protoc."},{"key":"D6FO01790H\/cit25\/1","first-page":"199","volume":"56","author":"Valcheva-Kuzmanova","year":"2014","journal-title":"Folia Med."},{"key":"D6FO01790H\/cit26\/1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.physbeh.2017.10.028","volume":"184","author":"Ramalho","year":"2018","journal-title":"Physiol. Behav."},{"key":"D6FO01790H\/cit27\/1","doi-asserted-by":"crossref","first-page":"128592","DOI":"10.1016\/j.ijbiomac.2023.128592","volume":"257","author":"Pan","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D6FO01790H\/cit28\/1","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.carres.2007.10.016","volume":"343","author":"Leal","year":"2008","journal-title":"Carbohydr. Res."},{"key":"D6FO01790H\/cit29\/1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0008-6215(96)00060-2","volume":"289","author":"Heyraud","year":"1966","journal-title":"Carbohydr. Res."},{"key":"D6FO01790H\/cit30\/1","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1016\/j.neuropharm.2011.08.042","volume":"61","author":"Knox","year":"2011","journal-title":"Neuropharmacology"},{"key":"D6FO01790H\/cit31\/1","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/nrd4295","volume":"13","author":"Kruse","year":"2014","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D6FO01790H\/cit32\/1","doi-asserted-by":"crossref","first-page":"682927","DOI":"10.3389\/fnbeh.2021.682927","volume":"15","author":"Salah","year":"2021","journal-title":"Front. Behav. Neurosci."},{"key":"D6FO01790H\/cit33\/1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.brainres.2011.08.006","volume":"1429","author":"Javadi-Paydar","year":"2012","journal-title":"Brain Res."},{"key":"D6FO01790H\/cit34\/1","doi-asserted-by":"crossref","first-page":"115252","DOI":"10.1016\/j.jep.2022.115252","volume":"293","author":"Wang","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"D6FO01790H\/cit35\/1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2174\/1570159X13666150716165726","volume":"14","author":"Ferreira-Vieira","year":"2016","journal-title":"Curr. Neuropharmacol."},{"key":"D6FO01790H\/cit36\/1","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.cbi.2008.05.026","volume":"175","author":"Dinamarca","year":"2008","journal-title":"Chem. \u2013 Biol. Interact."},{"key":"D6FO01790H\/cit37\/1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neuropharm.2013.07.004","volume":"76","author":"Anand","year":"2014","journal-title":"Neuropharmacology"},{"key":"D6FO01790H\/cit38\/1","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.3233\/JAD-161088","volume":"57","author":"T\u00f6nnies","year":"2017","journal-title":"J. Alzheimer's Dis."},{"key":"D6FO01790H\/cit39\/1","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1161\/CIRCRESAHA.116.303584","volume":"116","author":"Brown","year":"2015","journal-title":"Circ. Res."},{"key":"D6FO01790H\/cit40\/1","doi-asserted-by":"crossref","first-page":"e1005295","DOI":"10.1371\/journal.ppat.1005295","volume":"12","author":"Broxton","year":"2016","journal-title":"PLoS Pathog."},{"key":"D6FO01790H\/cit41\/1","doi-asserted-by":"crossref","first-page":"448","DOI":"10.2174\/138955709787847921","volume":"9","author":"Basavarajappa","year":"2009","journal-title":"Mini Rev. Med. Chem."},{"key":"D6FO01790H\/cit42\/1","doi-asserted-by":"crossref","first-page":"8400","DOI":"10.1073\/pnas.122196999","volume":"99","author":"Huang","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6FO01790H\/cit43\/1","doi-asserted-by":"crossref","first-page":"427","DOI":"10.5650\/jos.62.427","volume":"62","author":"Wang","year":"2013","journal-title":"J. Oleo Sci."},{"key":"D6FO01790H\/cit44\/1","doi-asserted-by":"crossref","first-page":"11181","DOI":"10.1073\/pnas.1221803110","volume":"110","author":"Rinaldo","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6FO01790H\/cit45\/1","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.3390\/nu13062099","volume":"13","author":"Chen","year":"2021","journal-title":"Nutrients"},{"key":"D6FO01790H\/cit46\/1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.2217\/fmb-2016-0130","volume":"12","author":"Tamanai-Shacoori","year":"2017","journal-title":"Future Microbiol."},{"key":"D6FO01790H\/cit47\/1","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.3390\/nu16091288","volume":"16","author":"Sun","year":"2024","journal-title":"Nutrients"},{"key":"D6FO01790H\/cit48\/1","doi-asserted-by":"crossref","first-page":"607","DOI":"10.3390\/ph14070607","volume":"14","author":"Sadovnikova","year":"2021","journal-title":"Pharmaceuticals"},{"key":"D6FO01790H\/cit49\/1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1080\/10408398.2023.2272769","volume":"65","author":"Guo","year":"2025","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"D6FO01790H\/cit50\/1","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1053\/j.gastro.2010.01.053","volume":"138","author":"Soret","year":"2010","journal-title":"Gastroenterology"}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/FO\/article-pdf\/doi\/10.1039\/D6FO01790H\/0\/D6FO01790H.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T12:07:50Z","timestamp":1784722070000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/FO\/article-lookup\/doi\/10.1039\/D6FO01790H"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":50,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2026,7,20]]}},"URL":"https:\/\/doi.org\/10.1039\/d6fo01790h","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}