{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:31:10Z","timestamp":1786984270790,"version":"build-2736575974"},"reference-count":45,"publisher":"Royal Society of Chemistry (RSC)","issue":"16","license":[{"start":{"date-parts":[[2027,7,21]],"date-time":"2027-07-21T00:00:00Z","timestamp":1816128000000},"content-version":"am","delay-in-days":566,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/100007847","name":"Natural Science Foundation of Jilin Province","doi-asserted-by":"publisher","award":["Grant No. YDZJ202501ZYTS814"],"award-info":[{"award-number":["Grant No. YDZJ202501ZYTS814"]}],"id":[{"id":"10.13039\/100007847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011789","name":"Department of Science and Technology of Jilin Province","doi-asserted-by":"publisher","award":["Grant No. 3D5223990429"],"award-info":[{"award-number":["Grant No. 3D5223990429"]}],"id":[{"id":"10.13039\/501100011789","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    Probiotic\n                    <jats:italic>Weizmannia coagulans<\/jats:italic>\n                    JA845 reshapes the gut microbiota\u2013bile acid axis to regulate TGR5\/FXR signaling, promotes GLP-1 release, and alleviates glycolipid metabolic dysfunction\n                    <jats:italic>in vitro<\/jats:italic>\n                    and\n                    <jats:italic>in vivo<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1039\/d6fo02139e","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T08:01:41Z","timestamp":1784620901000},"page":"7180-7200","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<i>Weizmannia coagulans<\/i>\n                    JA845 modulates glucose and lipid metabolism\n                    <i>via<\/i>\n                    the gut microbiota\u2013bile acid axis and FXR\/TGR5 signaling to enhance GLP-1 secretion"],"prefix":"10.1039","volume":"17","author":[{"given":"Haifei","family":"Guan","sequence":"first","affiliation":[{"name":"Department of Endocrinology, the Second Hospital of Jilin University, Changchun 130041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunlong","family":"Shang","sequence":"additional","affiliation":[{"name":"Special Medical Ward, Beijing Anzhen Hospital of Capital Medical University Jilin Campus, Changchun 130022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yansong","family":"Gao","sequence":"additional","affiliation":[{"name":"Institute of Agro-food Technology, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Changchun 130033, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Agro-food Technology, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Changchun 130033, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenrui","family":"Wang","sequence":"additional","affiliation":[{"name":"Digestive Diseases Center, Department of Hepatopancreatobiliary Medicine, the Second Hospital of Jilin University, Changchun 130041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4305-6306","authenticated-orcid":false,"given":"Shengyu","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Agro-food Technology, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Changchun 130033, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0638-3571","authenticated-orcid":false,"given":"Chuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, the Second Hospital of Jilin University, Changchun 130041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6FO02139E\/cit1\/1","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1007\/s11427-024-3036-4","volume":"69","author":"Chen","year":"2026","journal-title":"Sci. China: Life Sci."},{"key":"D6FO02139E\/cit2\/1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41572-026-00687-w","volume":"12","author":"Davies","year":"2026","journal-title":"Nat. Rev. Dis. Primers"},{"key":"D6FO02139E\/cit3\/1","first-page":"2022","volume":"12","author":"Zhou","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"D6FO02139E\/cit4\/1","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1038\/s41591-025-03642-6","volume":"31","author":"Wu","year":"2025","journal-title":"Nat. Med."},{"key":"D6FO02139E\/cit5\/1","doi-asserted-by":"crossref","first-page":"523","DOI":"10.3390\/fermentation9060523","volume":"9","author":"Kim","year":"2023","journal-title":"Fermentation"},{"key":"D6FO02139E\/cit6\/1","doi-asserted-by":"crossref","first-page":"4158","DOI":"10.1038\/s41598-020-60984-6","volume":"10","author":"Horiuchi","year":"2020","journal-title":"Sci. Rep."},{"key":"D6FO02139E\/cit7\/1","doi-asserted-by":"crossref","first-page":"5898","DOI":"10.1039\/C9FO02761K","volume":"11","author":"Wang","year":"2020","journal-title":"Food Funct."},{"key":"D6FO02139E\/cit8\/1","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1038\/s41467-017-01682-2","volume":"8","author":"Gu","year":"2017","journal-title":"Nat. Commun."},{"key":"D6FO02139E\/cit9\/1","doi-asserted-by":"crossref","first-page":"e00965-25","DOI":"10.1128\/msystems.00965-25","volume":"10","author":"Zhang","year":"2025","journal-title":"mSystems"},{"key":"D6FO02139E\/cit10\/1","doi-asserted-by":"crossref","first-page":"2474143","DOI":"10.1080\/19490976.2025.2474143","volume":"17","author":"Schlicht","year":"2025","journal-title":"Gut Microbes"},{"key":"D6FO02139E\/cit11\/1","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/s41586-023-06466-x","volume":"621","author":"Takeuchi","year":"2023","journal-title":"Nature"},{"key":"D6FO02139E\/cit12\/1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/s41586-025-09934-8","volume":"651","author":"Wang","year":"2026","journal-title":"Nature"},{"key":"D6FO02139E\/cit13\/1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jare.2024.06.027","volume":"72","author":"Huang","year":"2025","journal-title":"J. Adv. Res."},{"key":"D6FO02139E\/cit14\/1","doi-asserted-by":"crossref","first-page":"100115","DOI":"10.1016\/j.pharmr.2026.100115","volume":"78","author":"Ding","year":"2026","journal-title":"Pharmacol. Rev."},{"key":"D6FO02139E\/cit15\/1","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/s42255-022-00559-z","volume":"4","author":"Perino","year":"2022","journal-title":"Nat. Metab."},{"key":"D6FO02139E\/cit16\/1","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.cmet.2020.11.017","volume":"33","author":"Zheng","year":"2021","journal-title":"Cell Metab."},{"key":"D6FO02139E\/cit17\/1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3727\/105221618X15156018385515","volume":"18","author":"Chiang","year":"2018","journal-title":"Gene Expression"},{"key":"D6FO02139E\/cit18\/1","doi-asserted-by":"crossref","first-page":"101895","DOI":"10.1016\/j.toxrep.2025.101895","volume":"14","author":"Al-Noshokaty","year":"2025","journal-title":"Toxicol. Rep."},{"key":"D6FO02139E\/cit19\/1","doi-asserted-by":"crossref","first-page":"212","DOI":"10.4014\/jmb.2111.11031","volume":"32","author":"Song","year":"2022","journal-title":"J. Microbiol. Biotechnol."},{"key":"D6FO02139E\/cit20\/1","first-page":"134","author":"Ma","year":"2023","journal-title":"J. Appl. Microbiol."},{"key":"D6FO02139E\/cit21\/1","first-page":"17","author":"Ma","year":"2025","journal-title":"Nutrients"},{"key":"D6FO02139E\/cit22\/1","doi-asserted-by":"crossref","first-page":"21077","DOI":"10.1021\/acs.jafc.4c06030","volume":"72","author":"Sun","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"D6FO02139E\/cit23\/1","doi-asserted-by":"crossref","first-page":"116056","DOI":"10.1016\/j.intimp.2025.116056","volume":"170","author":"Gao","year":"2026","journal-title":"Int. Immunopharmacol."},{"key":"D6FO02139E\/cit24\/1","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/BF00280883","volume":"28","author":"Matthews","year":"1985","journal-title":"Diabetologia"},{"key":"D6FO02139E\/cit25\/1","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1136\/gutjnl-2015-309990","volume":"65","author":"Marchesi","year":"2016","journal-title":"Gut"},{"key":"D6FO02139E\/cit26\/1","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.3390\/microorganisms8111715","volume":"8","author":"Stojanov","year":"2020","journal-title":"Microorganisms"},{"key":"D6FO02139E\/cit27\/1","doi-asserted-by":"crossref","first-page":"4209","DOI":"10.3390\/nu14194209","volume":"14","author":"Jin","year":"2022","journal-title":"Nutrients"},{"key":"D6FO02139E\/cit28\/1","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/s41575-022-00631-9","volume":"19","author":"Cani","year":"2022","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"D6FO02139E\/cit29\/1","doi-asserted-by":"crossref","first-page":"25358","DOI":"10.1021\/acs.jafc.5c05449","volume":"73","author":"Bai","year":"2025","journal-title":"J. Agric. Food Chem."},{"key":"D6FO02139E\/cit30\/1","doi-asserted-by":"crossref","first-page":"24169","DOI":"10.1021\/acs.jafc.5c07346","volume":"73","author":"Chen","year":"2025","journal-title":"J. Agric. Food Chem."},{"key":"D6FO02139E\/cit31\/1","doi-asserted-by":"crossref","first-page":"155329","DOI":"10.1016\/j.phymed.2023.155329","volume":"132","author":"Liu","year":"2024","journal-title":"Phytomedicine"},{"key":"D6FO02139E\/cit32\/1","doi-asserted-by":"crossref","first-page":"e0085121","DOI":"10.1128\/msphere.00851-21","volume":"6","author":"Smith","year":"2021","journal-title":"mSphere"},{"key":"D6FO02139E\/cit33\/1","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.ijbiomac.2015.06.005","volume":"79","author":"Abdhul","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"key":"D6FO02139E\/cit34\/1","first-page":"13","author":"Yang","year":"2024","journal-title":"Foods"},{"key":"D6FO02139E\/cit35\/1","doi-asserted-by":"crossref","first-page":"1337185","DOI":"10.3389\/fmicb.2024.1337185","volume":"15","author":"Liu","year":"2024","journal-title":"Front. Microbiol."},{"key":"D6FO02139E\/cit36\/1","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.cmet.2013.03.013","volume":"17","author":"de Aguiar Vallim","year":"2013","journal-title":"Cell Metab."},{"key":"D6FO02139E\/cit37\/1","doi-asserted-by":"crossref","first-page":"7334","DOI":"10.1021\/acs.jafc.2c09151","volume":"71","author":"Wang","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"D6FO02139E\/cit38\/1","doi-asserted-by":"crossref","first-page":"G554","DOI":"10.1152\/ajpgi.00223.2019","volume":"318","author":"Chiang","year":"2020","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"D6FO02139E\/cit39\/1","doi-asserted-by":"crossref","first-page":"7629","DOI":"10.1038\/ncomms8629","volume":"6","author":"Trabelsi","year":"2015","journal-title":"Nat. Commun."},{"key":"D6FO02139E\/cit40\/1","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1038\/s41598-019-56743-x","volume":"10","author":"Ducastel","year":"2020","journal-title":"Sci. Rep."},{"key":"D6FO02139E\/cit41\/1","doi-asserted-by":"crossref","first-page":"2274124","DOI":"10.1080\/19490976.2023.2274124","volume":"15","author":"Wang","year":"2023","journal-title":"Gut Microbes"},{"key":"D6FO02139E\/cit42\/1","first-page":"2016","volume":"7","author":"Guo","year":"2016","journal-title":"Front. Physiol."},{"key":"D6FO02139E\/cit43\/1","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1096\/fj.201700845R","volume":"32","author":"Lee","year":"2018","journal-title":"FASEB J."},{"key":"D6FO02139E\/cit44\/1","doi-asserted-by":"crossref","first-page":"614","DOI":"10.2337\/db19-0764","volume":"69","author":"Lund","year":"2020","journal-title":"Diabetes"},{"key":"D6FO02139E\/cit45\/1","doi-asserted-by":"crossref","first-page":"7629","DOI":"10.1038\/ncomms8629","volume":"6","author":"Trabelsi","year":"2015","journal-title":"Nat. Commun."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/FO\/article-pdf\/doi\/10.1039\/D6FO02139E\/0\/D6FO02139E.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:03:41Z","timestamp":1786982621000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/FO\/article-lookup\/doi\/10.1039\/D6FO02139E"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":45,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2026,8,17]]}},"URL":"https:\/\/doi.org\/10.1039\/d6fo02139e","relation":{},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}