{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:30:35Z","timestamp":1786984235736,"version":"build-2736575974"},"reference-count":43,"publisher":"Royal Society of Chemistry (RSC)","issue":"16","license":[{"start":{"date-parts":[[2027,7,28]],"date-time":"2027-07-28T00:00:00Z","timestamp":1816732800000},"content-version":"am","delay-in-days":573,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Food Funct."],"abstract":"<jats:p>\n                    <jats:italic>Ulva<\/jats:italic>\n                    -derived nutritional nanovesicles: metabolomics-to-network pharmacology nomination and EGFR\u2013AKT validation.\n                  <\/jats:p>","DOI":"10.1039\/d6fo02503j","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T14:37:34Z","timestamp":1785249454000},"page":"7463-7477","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<i>Ulva<\/i>\n                    -derived extracellular vesicles alleviate liver injury through a 7-hydroxycoumarin-associated EGFR\u2013AKT regulatory axis"],"prefix":"10.1039","volume":"17","author":[{"given":"Jiaxuan","family":"Li","sequence":"first","affiliation":[{"name":"State Key Laboratory of Marine Food Processing and Safety Control, National Engineering Research Center of Seafood, School of Food Science and Technology, Academy of Food Interdisciplinary Science, Dalian Polytechnic University, Dalian 116034, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Marine Food Processing and Safety Control, National Engineering Research Center of Seafood, School of Food Science and Technology, Academy of Food Interdisciplinary Science, Dalian Polytechnic University, Dalian 116034, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongyu","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biotechnology and Bioresources Utilization, Ministry of Education, Dalian Minzu University, Dalian 116600, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xitao","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biotechnology and Bioresources Utilization, Ministry of Education, Dalian Minzu University, Dalian 116600, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyang","family":"Bao","sequence":"additional","affiliation":[{"name":"Dalian Blue Peptide Technology Research & Development Co., Ltd, Dalian 116085, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingqian","family":"Tan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Marine Food Processing and Safety Control, National Engineering Research Center of Seafood, School of Food Science and Technology, Academy of Food Interdisciplinary Science, Dalian Polytechnic University, Dalian 116034, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3628-2399","authenticated-orcid":false,"given":"Wentao","family":"Su","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Marine Food Processing and Safety Control, National Engineering Research Center of Seafood, School of Food Science and Technology, Academy of Food Interdisciplinary Science, Dalian Polytechnic University, Dalian 116034, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6FO02503J\/cit1\/1","doi-asserted-by":"crossref","first-page":"1541020","DOI":"10.3389\/fphys.2025.1541020","volume":"16","author":"Vincenzi","year":"2025","journal-title":"Front. Physiol."},{"key":"D6FO02503J\/cit2\/1","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1016\/j.ajpath.2023.06.002","volume":"193","author":"Banerjee","year":"2023","journal-title":"Am. J. Pathol."},{"key":"D6FO02503J\/cit3\/1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s00018-023-05061-7","volume":"81","author":"LeFort","year":"2024","journal-title":"Cell. Mol. Life Sci."},{"key":"D6FO02503J\/cit4\/1","doi-asserted-by":"crossref","first-page":"101976","DOI":"10.1016\/j.toxrep.2025.101976","volume":"14","author":"Tiwari","year":"2025","journal-title":"Toxicol. Rep."},{"key":"D6FO02503J\/cit5\/1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.37349\/edd.2023.00020","volume":"2","author":"Wu","year":"2023","journal-title":"Explor. Dig. Dis."},{"key":"D6FO02503J\/cit6\/1","doi-asserted-by":"crossref","first-page":"140168","DOI":"10.1016\/j.foodchem.2024.140168","volume":"457","author":"Rivero-Pino","year":"2024","journal-title":"Food Chem."},{"key":"D6FO02503J\/cit7\/1","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.3390\/antiox12101862","volume":"12","author":"Yeo","year":"2023","journal-title":"Antioxidants"},{"key":"D6FO02503J\/cit8\/1","doi-asserted-by":"crossref","first-page":"1307878","DOI":"10.3389\/fbioe.2023.1307878","volume":"11","author":"Mondal","year":"2023","journal-title":"Front. Bioeng. Biotechnol."},{"key":"D6FO02503J\/cit9\/1","doi-asserted-by":"crossref","first-page":"101300","DOI":"10.1016\/j.jpha.2025.101300","volume":"15","author":"Shen","year":"2025","journal-title":"Pharm. Anal."},{"key":"D6FO02503J\/cit10\/1","doi-asserted-by":"crossref","first-page":"12092","DOI":"10.3390\/ijms252212092","volume":"25","author":"Sha","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"D6FO02503J\/cit11\/1","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1007\/s13346-024-01698-4","volume":"15","author":"Langellotto","year":"2025","journal-title":"Drug Delivery Transl. Res."},{"key":"D6FO02503J\/cit12\/1","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/j.jare.2025.08.003","volume":"83","author":"Guan","year":"2025","journal-title":"J. Adv. Res."},{"key":"D6FO02503J\/cit13\/1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/s41538-024-00258-x","volume":"8","author":"Barathikannan","year":"2024","journal-title":"NPJ Sci. Food"},{"key":"D6FO02503J\/cit14\/1","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.3390\/ph18071052","volume":"18","author":"Li","year":"2025","journal-title":"Pharmaceuticals"},{"key":"D6FO02503J\/cit15\/1","doi-asserted-by":"crossref","first-page":"1466114","DOI":"10.3389\/fphar.2024.1466114","volume":"15","author":"Zeng","year":"2024","journal-title":"Front. Pharmacol."},{"key":"D6FO02503J\/cit16\/1","doi-asserted-by":"crossref","first-page":"119590","DOI":"10.1016\/j.jep.2025.119590","volume":"345","author":"Xiang","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"D6FO02503J\/cit17\/1","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1039\/D5FO03126E","volume":"17","author":"Li","year":"2026","journal-title":"Food Funct."},{"key":"D6FO02503J\/cit18\/1","doi-asserted-by":"crossref","first-page":"11319","DOI":"10.1039\/D4FO04321A","volume":"15","author":"Zeng","year":"2024","journal-title":"Food Funct."},{"key":"D6FO02503J\/cit19\/1","doi-asserted-by":"crossref","first-page":"15778","DOI":"10.1021\/acs.iecr.5c01363","volume":"64","author":"Onesti","year":"2025","journal-title":"Ind. Eng. Chem. Res."},{"key":"D6FO02503J\/cit20\/1","doi-asserted-by":"crossref","first-page":"e12404","DOI":"10.1002\/jev2.12404","volume":"13","author":"Welsh","year":"2024","journal-title":"J. Extracell. Vesicles"},{"key":"D6FO02503J\/cit21\/1","doi-asserted-by":"crossref","first-page":"13485","DOI":"10.2147\/IJN.S483253","volume":"19","author":"Selmani","year":"2024","journal-title":"Int. J. Nanomed."},{"key":"D6FO02503J\/cit22\/1","doi-asserted-by":"crossref","first-page":"101209","DOI":"10.1016\/j.drup.2025.101209","volume":"79","author":"Qian","year":"2025","journal-title":"Drug Resist. Updates"},{"key":"D6FO02503J\/cit23\/1","doi-asserted-by":"crossref","first-page":"116914","DOI":"10.1016\/j.taap.2024.116914","volume":"486","author":"Tao","year":"2024","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"D6FO02503J\/cit24\/1","doi-asserted-by":"crossref","first-page":"12975","DOI":"10.2147\/IJN.S526819","volume":"20","author":"Li","year":"2025","journal-title":"Int. J. Nanomed."},{"key":"D6FO02503J\/cit25\/1","doi-asserted-by":"crossref","first-page":"105734","DOI":"10.1016\/j.jff.2023.105734","volume":"108","author":"Hou","year":"2023","journal-title":"J. Funct. Foods"},{"key":"D6FO02503J\/cit26\/1","doi-asserted-by":"crossref","first-page":"1201583","DOI":"10.3389\/fphar.2023.1201583","volume":"14","author":"Mansouri","year":"2023","journal-title":"Front. Pharmacol."},{"key":"D6FO02503J\/cit27\/1","doi-asserted-by":"crossref","first-page":"124254","DOI":"10.1016\/j.jchromb.2024.124254","volume":"1244","author":"Wang","year":"2024","journal-title":"J. Chromatogr. B:Anal. Technol. Biomed. Life Sci."},{"key":"D6FO02503J\/cit28\/1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s13020-024-01056-z","volume":"20","author":"Zhai","year":"2025","journal-title":"China Med."},{"key":"D6FO02503J\/cit29\/1","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1007\/s00210-023-02404-w","volume":"396","author":"Cong","year":"2023","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"D6FO02503J\/cit30\/1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/s41420-018-0095-9","volume":"4","author":"Yu","year":"2018","journal-title":"Cell Death Discovery"},{"key":"D6FO02503J\/cit31\/1","doi-asserted-by":"crossref","first-page":"7331","DOI":"10.1007\/s00210-024-03712-5","volume":"398","author":"Fang","year":"2025","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"D6FO02503J\/cit32\/1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/978-1-0716-3203-1_5","volume":"2668","author":"Yuan","year":"2023","journal-title":"Methods Mol. Biol."},{"key":"D6FO02503J\/cit33\/1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/978-1-0716-4905-3_9","volume":"228","author":"Kaur","year":"2026","journal-title":"Neuromethods"},{"key":"D6FO02503J\/cit34\/1","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s13596-018-0318-x","volume":"18","author":"Lee","year":"2018","journal-title":"Orient. Pharm. Exp. Med."},{"key":"D6FO02503J\/cit35\/1","doi-asserted-by":"crossref","first-page":"116","DOI":"10.4274\/tjps.galenos.2021.08683","volume":"19","author":"Azam","year":"2022","journal-title":"Turk. J. Pharm. Sci."},{"key":"D6FO02503J\/cit36\/1","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1007\/s40005-024-00699-2","volume":"54","author":"Lu","year":"2024","journal-title":"J. Pharm. Invest."},{"key":"D6FO02503J\/cit37\/1","doi-asserted-by":"crossref","first-page":"1258138","DOI":"10.3389\/fphar.2023.1258138","volume":"14","author":"Xie","year":"2023","journal-title":"Front. Pharmacol."},{"key":"D6FO02503J\/cit38\/1","doi-asserted-by":"crossref","first-page":"102408","DOI":"10.1016\/j.mtbio.2025.102408","volume":"35","author":"Cao","year":"2025","journal-title":"Mater. Today Bio"},{"key":"D6FO02503J\/cit39\/1","doi-asserted-by":"crossref","first-page":"102920","DOI":"10.1016\/j.nantod.2025.102920","volume":"66","author":"Baby","year":"2026","journal-title":"Nano Today"},{"key":"D6FO02503J\/cit40\/1","doi-asserted-by":"crossref","first-page":"101223","DOI":"10.1016\/j.jhepr.2024.101223","volume":"7","author":"Merens","year":"2025","journal-title":"JHEP Rep."},{"key":"D6FO02503J\/cit41\/1","doi-asserted-by":"crossref","first-page":"3173","DOI":"10.1039\/D3AY00560G","volume":"15","author":"Xiao","year":"2023","journal-title":"Anal. Methods"},{"key":"D6FO02503J\/cit42\/1","first-page":"e65071","volume":"2023","author":"Zeng","year":"2023","journal-title":"J. Visualized Exp."},{"key":"D6FO02503J\/cit43\/1","doi-asserted-by":"crossref","first-page":"goaf022","DOI":"10.1093\/gastro\/goaf022","volume":"13","author":"Chen","year":"2025","journal-title":"Gastroenterol. Rep."}],"container-title":["Food &amp; Function"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/FO\/article-pdf\/doi\/10.1039\/D6FO02503J\/0\/D6FO02503J.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:58:41Z","timestamp":1786982321000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/FO\/article-lookup\/doi\/10.1039\/D6FO02503J"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":43,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2026,8,17]]}},"URL":"https:\/\/doi.org\/10.1039\/d6fo02503j","relation":{"has-review":[{"id-type":"doi","id":"10.1039\/D6FO02503J\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6FO02503J\/v3\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6FO02503J\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6FO02503J\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6FO02503J\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6FO02503J\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6FO02503J\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6FO02503J\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1039\/D6FO02503J\/v1\/decision1","asserted-by":"object"}]},"ISSN":["2042-6496","2042-650X"],"issn-type":[{"value":"2042-6496","type":"print"},{"value":"2042-650X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}