{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T23:23:31Z","timestamp":1789169011421,"version":"build-2803163510"},"reference-count":26,"publisher":"Royal Society of Chemistry (RSC)","issue":"14","license":[{"start":{"date-parts":[[2027,6,25]],"date-time":"2027-06-25T00:00:00Z","timestamp":1813881600000},"content-version":"am","delay-in-days":540,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100018628","name":"Scientific Research Foundation of Education Department of Anhui Province of China","doi-asserted-by":"publisher","award":["2024AH051911"],"award-info":[{"award-number":["2024AH051911"]}],"id":[{"id":"10.13039\/501100018628","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22377055"],"award-info":[{"award-number":["22377055"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82572370"],"award-info":[{"award-number":["82572370"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Lab Chip"],"abstract":"<jats:p>\n                    Heavy metal pollution threatens human health. We developed a CRISPR-Cas12a\/MOF bio-barcode platform for ultrasensitive detection of Cu\n                    <jats:sup>2+<\/jats:sup>\n                    , Pb\n                    <jats:sup>2+<\/jats:sup>\n                    and Hg\n                    <jats:sup>2+<\/jats:sup>\n                    . Integrated with a microfluidic chip and smartphone, it enables portable on-site analysis.\n                  <\/jats:p>","DOI":"10.1039\/d6lc00331a","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T12:43:39Z","timestamp":1782391419000},"page":"4229-4234","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater"],"prefix":"10.1039","volume":"26","author":[{"given":"Ping","family":"Dong","sequence":"first","affiliation":[{"name":"Key Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5972-8993","authenticated-orcid":false,"given":"Yanfeng","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Medical Imaging, Wannan Medical University, Wuhu 241002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjian","family":"Zhao","sequence":"additional","affiliation":[{"name":"College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Nanjing 210023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingtao","family":"Fan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6199-1053","authenticated-orcid":false,"given":"Yuzhen","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM) & School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing 211816, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"issue":"1","key":"D6LC00331A\/cit1\/1","doi-asserted-by":"crossref","first-page":"6480","DOI":"10.1038\/s41467-022-34086-y","volume":"13","author":"Xu","year":"2022","journal-title":"Nat. Commun."},{"key":"D6LC00331A\/cit2\/1","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1007\/s10311-019-00891-z","volume":"17","author":"Malik","year":"2019","journal-title":"Environ. Chem. Lett."},{"key":"D6LC00331A\/cit3\/1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.talanta.2012.03.066","volume":"97","author":"Bagheri","year":"2012","journal-title":"Talanta"},{"key":"D6LC00331A\/cit4\/1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.bios.2016.11.039","volume":"90","author":"Saidur","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"D6LC00331A\/cit5\/1","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.foodchem.2011.09.009","volume":"131","author":"Djedjibegovic","year":"2012","journal-title":"Food Chem."},{"key":"D6LC00331A\/cit6\/1","doi-asserted-by":"crossref","first-page":"120245","DOI":"10.1016\/j.cca.2025.120245","volume":"572","author":"He","year":"2025","journal-title":"Clin. Chim. Acta"},{"key":"D6LC00331A\/cit7\/1","doi-asserted-by":"crossref","first-page":"10719","DOI":"10.1021\/acs.analchem.1c02478","volume":"93","author":"Gong","year":"2021","journal-title":"Anal. Chem."},{"key":"D6LC00331A\/cit8\/1","first-page":"1618","volume":"95","author":"Long","year":"2023","journal-title":"Anal. Chem."},{"key":"D6LC00331A\/cit9\/1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.coelec.2020.03.003","volume":"23","author":"Kowalczyk","year":"2020","journal-title":"Curr. Opin. Electrochem."},{"key":"D6LC00331A\/cit10\/1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1021\/acssensors.9b01759","volume":"5","author":"Meng","year":"2020","journal-title":"ACS Sens."},{"key":"D6LC00331A\/cit11\/1","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.bios.2014.04.031","volume":"60","author":"Li","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"D6LC00331A\/cit12\/1","doi-asserted-by":"crossref","first-page":"9714","DOI":"10.1021\/acs.nanolett.2c04022","volume":"22","author":"Zhao","year":"2022","journal-title":"Nano Lett."},{"key":"D6LC00331A\/cit13\/1","doi-asserted-by":"crossref","first-page":"103625","DOI":"10.1016\/j.eti.2024.103625","volume":"34","author":"Wani","year":"2024","journal-title":"Environ. Technol. Innovation"},{"issue":"1","key":"D6LC00331A\/cit14\/1","doi-asserted-by":"crossref","first-page":"4278","DOI":"10.1038\/s41467-023-39844-0","volume":"14","author":"Zhang","year":"2023","journal-title":"Nat. Commun."},{"key":"D6LC00331A\/cit15\/1","doi-asserted-by":"crossref","first-page":"5010","DOI":"10.1021\/acsami.2c21350","volume":"15","author":"Gao","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D6LC00331A\/cit16\/1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1039\/D4LC00619D","volume":"25","author":"Jiang","year":"2024","journal-title":"Lab Chip"},{"issue":"4","key":"D6LC00331A\/cit17\/1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/s40735-018-0188-2","volume":"4","author":"Mathew","year":"2018","journal-title":"J. Bio- Tribo-Corros."},{"key":"D6LC00331A\/cit18\/1","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1021\/ja2086323","volume":"134","author":"Shao","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"D6LC00331A\/cit19\/1","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.bios.2018.06.046","volume":"117","author":"Liu","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"D6LC00331A\/cit20\/1","doi-asserted-by":"crossref","first-page":"3521","DOI":"10.1039\/D4LC00290C","volume":"24","author":"Wang","year":"2024","journal-title":"Lab Chip"},{"key":"D6LC00331A\/cit21\/1","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1021\/acssensors.4c03384","volume":"10","author":"Bi","year":"2025","journal-title":"ACS Sens."},{"key":"D6LC00331A\/cit22\/1","doi-asserted-by":"crossref","first-page":"3395","DOI":"10.1021\/acs.analchem.4c05427","volume":"97","author":"Luan","year":"2025","journal-title":"Anal. Chem."},{"key":"D6LC00331A\/cit23\/1","doi-asserted-by":"crossref","first-page":"125547","DOI":"10.1016\/j.envpol.2024.125547","volume":"366","author":"Herath","year":"2025","journal-title":"Environ. Pollut."},{"key":"D6LC00331A\/cit24\/1","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.snb.2017.12.056","volume":"259","author":"Chen","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"D6LC00331A\/cit25\/1","doi-asserted-by":"crossref","first-page":"5538","DOI":"10.1039\/D2CC01341J","volume":"58","author":"Zhang","year":"2022","journal-title":"Chem. Commun."},{"key":"D6LC00331A\/cit26\/1","doi-asserted-by":"crossref","first-page":"7261","DOI":"10.1021\/ja503215w","volume":"136","author":"Morris","year":"2014","journal-title":"J. Am. Chem. Soc."}],"container-title":["Lab on a Chip"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/LC\/article-pdf\/doi\/10.1039\/D6LC00331A\/0\/D6LC00331A.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T16:10:25Z","timestamp":1784045425000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/LC\/article-lookup\/doi\/10.1039\/D6LC00331A"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":26,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2026,7,14]]}},"URL":"https:\/\/doi.org\/10.1039\/d6lc00331a","relation":{},"ISSN":["1473-0197","1473-0189"],"issn-type":[{"value":"1473-0197","type":"print"},{"value":"1473-0189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}