{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:55:58Z","timestamp":1791280558096,"version":"4.1.0"},"reference-count":100,"publisher":"Royal Society of Chemistry (RSC)","license":[{"start":{"date-parts":[[2027,9,29]],"date-time":"2027-09-29T00:00:00Z","timestamp":1822176000000},"content-version":"am","delay-in-days":636,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["RSC Med. Chem."],"abstract":"<jats:p>This review presents a precision pharmacology framework connecting natural scaffolds, multitarget mechanisms, and TNBC vulnerabilities, addresses translational barriers, and outlines a phenotypic-driven roadmap for precision medicine in TNBC.<\/jats:p>","DOI":"10.1039\/d6md00590j","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:03:58Z","timestamp":1790661838000},"update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mechanism-based precision pharmacology of natural products for triple-negative breast cancer: translational opportunities for targeted therapeutics"],"prefix":"10.1039","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1820-9979","authenticated-orcid":false,"given":"Hadir M.","family":"Emara","sequence":"first","affiliation":[{"name":"Energy Materials Laboratory, School of Sciences & Engineering, The American University in Cairo, New Cairo, 11835, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9458-3507","authenticated-orcid":false,"given":"Nageh K.","family":"Allam","sequence":"additional","affiliation":[{"name":"Energy Materials Laboratory, School of Sciences & Engineering, The American University in Cairo, New Cairo, 11835, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6MD00590J\/cit1\/1","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s12672-025-02227-6","volume":"16","author":"Emara","year":"2025","journal-title":"Discover Oncol."},{"key":"D6MD00590J\/cit2\/1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1158\/2159-8290.CD-21-1059","volume":"12","author":"Hanahan","year":"2022","journal-title":"Cancer Discovery"},{"key":"D6MD00590J\/cit3\/1","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3322\/caac.21834","volume":"74","author":"Bray","year":"2024","journal-title":"Ca-Cancer J. Clin."},{"key":"D6MD00590J\/cit4\/1","doi-asserted-by":"crossref","first-page":"2750","DOI":"10.1172\/JCI45014","volume":"121","author":"Lehmann","year":"2011","journal-title":"J. Clin. Invest."},{"key":"D6MD00590J\/cit5\/1","doi-asserted-by":"crossref","first-page":"104203","DOI":"10.1016\/j.esmoop.2025.104203","volume":"10","author":"Emara","year":"2025","journal-title":"ESMO Open"},{"key":"D6MD00590J\/cit6\/1","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1039\/D5NA01082A","volume":"8","author":"Emara","year":"2026","journal-title":"Nanoscale Adv."},{"key":"D6MD00590J\/cit7\/1","doi-asserted-by":"crossref","first-page":"111650","DOI":"10.1016\/j.biopha.2021.111650","volume":"139","author":"Issinger","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"D6MD00590J\/cit8\/1","doi-asserted-by":"crossref","first-page":"108978","DOI":"10.1016\/j.jddst.2026.108978","volume":"127","author":"Emara","year":"2027","journal-title":"J. Drug Delivery Sci. Technol."},{"key":"D6MD00590J\/cit9\/1","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.bbrc.2011.02.010","volume":"406","author":"Van Aller","year":"2011","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"D6MD00590J\/cit10\/1","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.2174\/18715206113139990114","volume":"13","author":"Bruning","year":"2013","journal-title":"Anti-Cancer Agents Med. Chem."},{"key":"D6MD00590J\/cit11\/1","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s13578-017-0179-x","volume":"7","author":"Yan","year":"2017","journal-title":"Cell Biosci."},{"key":"D6MD00590J\/cit12\/1","doi-asserted-by":"crossref","first-page":"8323","DOI":"10.1038\/s41598-018-25524-3","volume":"8","author":"Siddiqui","year":"2018","journal-title":"Sci. Rep."},{"key":"D6MD00590J\/cit13\/1","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.2174\/18715206113139990113","volume":"13","author":"Wu","year":"2013","journal-title":"Anti-Cancer Agents Med. Chem."},{"key":"D6MD00590J\/cit14\/1","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.2174\/18715206113139990078","volume":"13","author":"Ahmad","year":"2013","journal-title":"Anti-Cancer Agents Med. Chem."},{"key":"D6MD00590J\/cit15\/1","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.2174\/18715206113139990130","volume":"13","author":"Sun","year":"2013","journal-title":"Anti-Cancer Agents Med. Chem."},{"key":"D6MD00590J\/cit16\/1","doi-asserted-by":"crossref","first-page":"96","DOI":"10.46439\/signaling.2.037","volume":"2","author":"Sahu","year":"2024","journal-title":"Cell. Signalling"},{"key":"D6MD00590J\/cit17\/1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.34297\/AJBSR.2020.08.001298","volume":"8","author":"Ahmad","year":"2020","journal-title":"Am. J. Biomed. Sci. Res."},{"key":"D6MD00590J\/cit18\/1","doi-asserted-by":"crossref","first-page":"880643","DOI":"10.3389\/fonc.2022.880643","volume":"12","author":"Mekonnen","year":"2022","journal-title":"Front. Oncol."},{"key":"D6MD00590J\/cit19\/1","doi-asserted-by":"crossref","first-page":"11441","DOI":"10.3390\/ijms222111441","volume":"22","author":"Maluchenko","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"D6MD00590J\/cit20\/1","doi-asserted-by":"crossref","first-page":"103698","DOI":"10.1016\/j.sjbs.2023.103698","volume":"30","author":"Tharamelveliyil Rajendran","year":"2023","journal-title":"Saudi J. Biol. Sci."},{"key":"D6MD00590J\/cit21\/1","doi-asserted-by":"crossref","first-page":"794","DOI":"10.30574\/wjarr.2022.16.3.1378","volume":"16","author":"Verma","year":"2022","journal-title":"World J. Adv. Res. Rev."},{"key":"D6MD00590J\/cit22\/1","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.3390\/ijms20061274","volume":"20","author":"Alqahtani","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"D6MD00590J\/cit23\/1","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1093\/jpp\/rgaf006","volume":"77","author":"Lin","year":"2025","journal-title":"J. Pharm. Pharmacol."},{"key":"D6MD00590J\/cit24\/1","doi-asserted-by":"crossref","first-page":"80","DOI":"10.3390\/ph10040080","volume":"10","author":"Su","year":"2017","journal-title":"Pharmaceuticals"},{"key":"D6MD00590J\/cit25\/1","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1093\/jn\/137.10.2190","volume":"137","author":"Geraets","year":"2007","journal-title":"J. Nutr."},{"key":"D6MD00590J\/cit26\/1","doi-asserted-by":"crossref","first-page":"11548","DOI":"10.1200\/JCO.2016.34.15_suppl.11548","volume":"34","author":"Gatalica","year":"2016","journal-title":"J. Clin. Oncol."},{"key":"D6MD00590J\/cit27\/1","doi-asserted-by":"crossref","first-page":"995461","DOI":"10.3389\/fonc.2022.995461","volume":"12","author":"Li","year":"2022","journal-title":"Front. Oncol."},{"key":"D6MD00590J\/cit28\/1","doi-asserted-by":"crossref","first-page":"1483459","DOI":"10.3389\/fimmu.2024.1483459","volume":"15","author":"Fang","year":"2024","journal-title":"Front. Immunol."},{"key":"D6MD00590J\/cit29\/1","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.3390\/ph14111081","volume":"14","author":"Ravindran Menon","year":"2021","journal-title":"Pharmaceuticals"},{"key":"D6MD00590J\/cit30\/1","doi-asserted-by":"crossref","first-page":"727","DOI":"10.3390\/cancers12030727","volume":"12","author":"Kang","year":"2020","journal-title":"Cancers"},{"key":"D6MD00590J\/cit31\/1","doi-asserted-by":"crossref","first-page":"1349745","DOI":"10.3389\/fphar.2024.1349745","volume":"15","author":"Ray","year":"2024","journal-title":"Front. Pharmacol."},{"key":"D6MD00590J\/cit32\/1","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.7150\/jca.85966","volume":"14","author":"Luo","year":"2023","journal-title":"J. Cancer"},{"key":"D6MD00590J\/cit33\/1","doi-asserted-by":"crossref","first-page":"1168226","DOI":"10.3389\/fonc.2023.1168226","volume":"13","author":"Zheng","year":"2023","journal-title":"Front. Oncol."},{"key":"D6MD00590J\/cit34\/1","doi-asserted-by":"crossref","first-page":"116735","DOI":"10.1016\/j.jep.2023.116735","volume":"316","author":"Song","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"D6MD00590J\/cit35\/1","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1016\/j.apsb.2020.06.014","volume":"10","author":"Liu","year":"2020","journal-title":"Acta Pharm. Sin. B"},{"key":"D6MD00590J\/cit36\/1","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.canlet.2008.05.025","volume":"270","author":"Liang","year":"2008","journal-title":"Cancer Lett."},{"key":"D6MD00590J\/cit37\/1","doi-asserted-by":"crossref","first-page":"130458","DOI":"10.1016\/j.ijbiomac.2024.130458","volume":"264","author":"Domingo-Contreras","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"D6MD00590J\/cit38\/1","doi-asserted-by":"crossref","first-page":"887457","DOI":"10.3389\/fphar.2022.887457","volume":"13","author":"Wang","year":"2022","journal-title":"Front. Pharmacol."},{"key":"D6MD00590J\/cit39\/1","doi-asserted-by":"crossref","first-page":"1714898","DOI":"10.3389\/fimmu.2025.1714898","volume":"16","author":"Wang","year":"2025","journal-title":"Front. Immunol."},{"key":"D6MD00590J\/cit40\/1","doi-asserted-by":"crossref","first-page":"4062","DOI":"10.3390\/molecules24224062","volume":"24","author":"Li","year":"2019","journal-title":"Molecules"},{"key":"D6MD00590J\/cit41\/1","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1177\/10781552231153814","volume":"29","author":"Orrico","year":"2023","journal-title":"J. Oncol. Pharm. Pract."},{"key":"D6MD00590J\/cit42\/1","doi-asserted-by":"crossref","first-page":"801733","DOI":"10.3389\/fphar.2022.801733","volume":"13","author":"Singla","year":"2022","journal-title":"Front. Pharmacol."},{"key":"D6MD00590J\/cit43\/1","doi-asserted-by":"crossref","first-page":"212","DOI":"10.2174\/0929867328666210303101345","volume":"29","author":"Nandi","year":"2022","journal-title":"Curr. Med. Chem."},{"key":"D6MD00590J\/cit44\/1","doi-asserted-by":"crossref","first-page":"3636","DOI":"10.7150\/ijbs.71870","volume":"18","author":"Mhone","year":"2022","journal-title":"Int. J. Biol. Sci."},{"key":"D6MD00590J\/cit45\/1","doi-asserted-by":"crossref","first-page":"5891016","DOI":"10.1155\/2020\/5891016","volume":"2020","author":"Yang","year":"2020","journal-title":"BioMed Res. Int."},{"key":"D6MD00590J\/cit46\/1","doi-asserted-by":"crossref","first-page":"993562","DOI":"10.3389\/fphar.2022.993562","volume":"13","author":"Javed","year":"2022","journal-title":"Front. Pharmacol."},{"key":"D6MD00590J\/cit47\/1","doi-asserted-by":"crossref","first-page":"3765","DOI":"10.3390\/ijms22073765","volume":"22","author":"Lopes-Coelho","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"D6MD00590J\/cit48\/1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.cpan.2025.02.001","volume":"21","author":"Bolleddu","year":"2025","journal-title":"Curr. Pharm. Anal."},{"key":"D6MD00590J\/cit49\/1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1186\/s13046-018-0785-4","volume":"37","author":"Shen","year":"2018","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"D6MD00590J\/cit50\/1","doi-asserted-by":"crossref","first-page":"698352","DOI":"10.3389\/fphar.2021.698352","volume":"12","author":"Tayarani-Najaran","year":"2021","journal-title":"Front. Pharmacol."},{"key":"D6MD00590J\/cit51\/1","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1016\/j.ygeno.2019.11.005","volume":"112","author":"Hu","year":"2020","journal-title":"Genomics"},{"key":"D6MD00590J\/cit52\/1","first-page":"405","volume":"32","author":"Chen","year":"2008","journal-title":"Int. J. Oncol."},{"key":"D6MD00590J\/cit53\/1","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1210\/me.2014-1170","volume":"28","author":"Hessenkemper","year":"2014","journal-title":"Mol. Endocrinol."},{"key":"D6MD00590J\/cit54\/1","doi-asserted-by":"crossref","first-page":"14356","DOI":"10.3390\/ijms232214356","volume":"23","author":"Kudo","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"D6MD00590J\/cit55\/1","doi-asserted-by":"crossref","first-page":"132","DOI":"10.7324\/JAPS.2021.110715","volume":"11","author":"Asiat","year":"2021","journal-title":"J. Appl. Pharm. Sci."},{"key":"D6MD00590J\/cit56\/1","doi-asserted-by":"crossref","first-page":"84","DOI":"10.18632\/genesandcancer.40","volume":"6","author":"Shvartsur","year":"2014","journal-title":"Genes Cancer"},{"issue":"2","key":"D6MD00590J\/cit57\/1","first-page":"3459","volume":"53","author":"Zhang","year":"2018","journal-title":"Int. J. Oncol."},{"key":"D6MD00590J\/cit58\/1","doi-asserted-by":"crossref","first-page":"609275","DOI":"10.3389\/fonc.2020.609275","volume":"10","author":"Zheng","year":"2021","journal-title":"Front. Oncol."},{"key":"D6MD00590J\/cit59\/1","doi-asserted-by":"crossref","first-page":"780","DOI":"10.3390\/cimb47090780","volume":"47","author":"Wu","year":"2025","journal-title":"Curr. Issues Mol. Biol."},{"key":"D6MD00590J\/cit60\/1","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1186\/s12935-022-02677-w","volume":"22","author":"Asgharian","year":"2022","journal-title":"Cancer Cell Int."},{"key":"D6MD00590J\/cit61\/1","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1038\/sj.bjp.0702879","volume":"128","author":"Huang","year":"1999","journal-title":"Br. J. Pharmacol."},{"key":"D6MD00590J\/cit62\/1","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3390\/pharmaceutics12020096","volume":"12","author":"Fathy Abd-Ellatef","year":"2020","journal-title":"Pharmaceutics"},{"key":"D6MD00590J\/cit63\/1","doi-asserted-by":"crossref","first-page":"1642248","DOI":"10.3389\/fphar.2025.1642248","volume":"16","author":"Liu","year":"2025","journal-title":"Front. Pharmacol."},{"key":"D6MD00590J\/cit64\/1","doi-asserted-by":"crossref","first-page":"103272","DOI":"10.1016\/j.jri.2021.103272","volume":"144","author":"Alharbi","year":"2021","journal-title":"J. Reprod. Immunol."},{"key":"D6MD00590J\/cit65\/1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3892\/ol.2016.5391","volume":"13","author":"Jin","year":"2017","journal-title":"Oncol. Lett."},{"key":"D6MD00590J\/cit66\/1","doi-asserted-by":"crossref","first-page":"2822","DOI":"10.1002\/jcp.27100","volume":"234","author":"Chen","year":"2019","journal-title":"J. Cell. Physiol."},{"key":"D6MD00590J\/cit67\/1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.2147\/CMAR.S4544","volume":"1","author":"Nguyen","year":"2009","journal-title":"Cancer Manag. Res."},{"key":"D6MD00590J\/cit68\/1","doi-asserted-by":"crossref","first-page":"52783","DOI":"10.18632\/oncotarget.17189","volume":"8","author":"Huang","year":"2017","journal-title":"Oncotarget"},{"key":"D6MD00590J\/cit69\/1","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1158\/1940-6207.CAPR-14-0324","volume":"8","author":"Kumar","year":"2015","journal-title":"Cancer Prev. Res."},{"key":"D6MD00590J\/cit70\/1","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1177\/107327481602300413","volume":"23","author":"Kumar","year":"2016","journal-title":"Cancer Control"},{"key":"D6MD00590J\/cit71\/1","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1158\/1940-6207.CAPR-08-0167","volume":"2","author":"McLarty","year":"2009","journal-title":"Cancer Prev. Res."},{"key":"D6MD00590J\/cit72\/1","doi-asserted-by":"crossref","first-page":"PR-05","DOI":"10.1158\/1940-6207.PREV-10-PR-05","volume":"3","author":"Campbell","year":"2010","journal-title":"Cancer Prev. Res."},{"key":"D6MD00590J\/cit73\/1","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1159\/000151537","volume":"8","author":"Hern\u0144dez-Mu\u00f1oz","year":"2008","journal-title":"Pancreatology"},{"key":"D6MD00590J\/cit74\/1","doi-asserted-by":"crossref","first-page":"5002","DOI":"10.3390\/ijms21145002","volume":"21","author":"Akhtar","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"D6MD00590J\/cit75\/1","doi-asserted-by":"crossref","first-page":"216","DOI":"10.3390\/cancers13020216","volume":"13","author":"Hideshima","year":"2021","journal-title":"Cancers"},{"key":"D6MD00590J\/cit76\/1","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.canlet.2017.11.020","volume":"414","author":"Hu","year":"2018","journal-title":"Cancer Lett."},{"key":"D6MD00590J\/cit77\/1","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1053\/j.gastro.2018.05.031","volume":"155","author":"Cruz-Correa","year":"2018","journal-title":"Gastroenterology"},{"key":"D6MD00590J\/cit78\/1","doi-asserted-by":"crossref","first-page":"3001","DOI":"10.3390\/cancers14123001","volume":"14","author":"Aromokeye","year":"2022","journal-title":"Cancers"},{"key":"D6MD00590J\/cit79\/1","doi-asserted-by":"crossref","first-page":"8165686","DOI":"10.1155\/proc\/8165686","volume":"2025","author":"Naiki","year":"2025","journal-title":"Prostate Cancer"},{"key":"D6MD00590J\/cit80\/1","doi-asserted-by":"crossref","first-page":"9003","DOI":"10.1158\/0008-5472.CAN-10-2364","volume":"70","author":"Brown","year":"2010","journal-title":"Cancer Res."},{"key":"D6MD00590J\/cit81\/1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s43556-024-00184-0","volume":"5","author":"Xue","year":"2024","journal-title":"Mol. Biomed."},{"key":"D6MD00590J\/cit82\/1","doi-asserted-by":"crossref","first-page":"2776","DOI":"10.1002\/ptr.8510","volume":"39","author":"Tu","year":"2025","journal-title":"Phytother. Res."},{"key":"D6MD00590J\/cit83\/1","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1158\/1940-6207.CAPR-11-0148","volume":"4","author":"Howells","year":"2011","journal-title":"Cancer Prev. Res."},{"key":"D6MD00590J\/cit84\/1","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s00044-020-02657-7","volume":"30","author":"Verma","year":"2021","journal-title":"Med. Chem. Res."},{"key":"D6MD00590J\/cit85\/1","doi-asserted-by":"crossref","first-page":"5373","DOI":"10.3390\/cancers14215373","volume":"14","author":"Singh Tuli","year":"2022","journal-title":"Cancers"},{"key":"D6MD00590J\/cit86\/1","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1097\/FPC.0b013e32833ffb56","volume":"21","author":"Thorn","year":"2011","journal-title":"Pharmacogenet. Genomics"},{"key":"D6MD00590J\/cit87\/1","first-page":"753","volume":"55","author":"Wall","year":"1995","journal-title":"Cancer Res."},{"key":"D6MD00590J\/cit88\/1","doi-asserted-by":"crossref","first-page":"108","DOI":"10.5455\/pt.2024.09","volume":"2","author":"Sabrina","year":"2024","journal-title":"Plant Trends"},{"key":"D6MD00590J\/cit89\/1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s00280-012-1963-2","volume":"71","author":"Nemunaitis","year":"2013","journal-title":"Cancer Chemother. Pharmacol."},{"key":"D6MD00590J\/cit90\/1","doi-asserted-by":"crossref","first-page":"1406247","DOI":"10.3389\/fphar.2024.1406247","volume":"15","author":"Xie","year":"2024","journal-title":"Front. Pharmacol."},{"key":"D6MD00590J\/cit91\/1","volume-title":"StatPearls","author":"Sinawe","year":"2026","unstructured":"H.Sinawe  and  D.Casadesus , in  StatPearls ,  StatPearls Publishing ,  Treasure Island, FL ,  2026"},{"key":"D6MD00590J\/cit92\/1","doi-asserted-by":"crossref","first-page":"v7","DOI":"10.1093\/annonc\/mdj941","volume":"17","author":"Mini","year":"2006","journal-title":"Ann. Oncol."},{"key":"D6MD00590J\/cit93\/1","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.3390\/ijms25021063","volume":"25","author":"Menyh\u00e1rt","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"D6MD00590J\/cit94\/1","doi-asserted-by":"crossref","first-page":"e803","DOI":"10.1097\/MD.0000000000000803","volume":"94","author":"Zheng","year":"2015","journal-title":"Medicine"},{"key":"D6MD00590J\/cit95\/1","doi-asserted-by":"crossref","first-page":"P5-08-05","DOI":"10.1158\/0008-5472.SABCS13-P5-08-05","volume":"73","author":"Austreid","year":"2013","journal-title":"Cancer Res."},{"key":"D6MD00590J\/cit96\/1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12885-023-11616-5","volume":"24","author":"Choulli","year":"2024","journal-title":"BMC Cancer"},{"key":"D6MD00590J\/cit97\/1","doi-asserted-by":"crossref","first-page":"28514","DOI":"10.18632\/oncotarget.25530","volume":"9","author":"Pandey","year":"2018","journal-title":"Oncotarget"},{"key":"D6MD00590J\/cit98\/1","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1002\/med.21565","volume":"39","author":"Singh","year":"2019","journal-title":"Med. Res. Rev."},{"key":"D6MD00590J\/cit99\/1","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.3390\/jcm11092331","volume":"11","author":"Nishimura","year":"2022","journal-title":"J. Clin. Med."},{"key":"D6MD00590J\/cit100\/1","doi-asserted-by":"crossref","first-page":"108978","DOI":"10.1016\/j.jddst.2026.108978","volume":"127","author":"Emara","year":"2026","journal-title":"J. Drug Delivery Sci. Technol."}],"container-title":["RSC Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/MD\/article-pdf\/doi\/10.1039\/D6MD00590J\/0\/D6MD00590J.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:38:13Z","timestamp":1791279493000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsc.org\/MD\/article-lookup\/doi\/10.1039\/D6MD00590J"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":100,"URL":"https:\/\/doi.org\/10.1039\/d6md00590j","relation":{},"ISSN":["2632-8682"],"issn-type":[{"value":"2632-8682","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}