{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T19:25:03Z","timestamp":1793733903020,"version":"4.6.1"},"reference-count":48,"publisher":"Royal Society of Chemistry (RSC)","issue":"13","license":[{"start":{"date-parts":[[2027,5,1]],"date-time":"2027-05-01T00:00:00Z","timestamp":1809129600000},"content-version":"am","delay-in-days":485,"URL":"http:\/\/rsc.li\/journals-terms-of-use"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP2000647"],"award-info":[{"award-number":["APP2000647"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82370932"],"award-info":[{"award-number":["82370932"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82001016"],"award-info":[{"award-number":["82001016"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004829","name":"Science and Technology Department of Sichuan Province","doi-asserted-by":"publisher","award":["2025ZNSFSC1579"],"award-info":[{"award-number":["2025ZNSFSC1579"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004829","name":"Science and Technology Department of Sichuan Province","doi-asserted-by":"publisher","award":["2024YFFK0204"],"award-info":[{"award-number":["2024YFFK0204"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rsc.org"],"crossmark-restriction":true},"short-container-title":["Mater. Horiz."],"abstract":"<jats:p>M2 macrophage membrane-camouflaged selenium nanospheres\u2019 dual-action cytokine decoy and metabolic reprogramming orchestrate inflammatory bone regeneration.<\/jats:p>","DOI":"10.1039\/d6mh00561f","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T09:40:48Z","timestamp":1777628448000},"page":"6601-6620","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Inflammatory cytokine scavenging and macrophage metabolism reprogramming to orchestrate inflammatory bone regeneration"],"prefix":"10.1039","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0543-5102","authenticated-orcid":false,"given":"Ze","family":"He","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China"},{"name":"School of Medicine and Dentistry, Griffith University, Gold Coast Campus, QLD 4222, Australia"},{"name":"Institute for Biomedicine and Glycomics, Griffith University, Southport QLD 4222, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-qing","family":"Mu","sequence":"additional","affiliation":[{"name":"School of Medicine and Dentistry, Griffith University, Gold Coast Campus, QLD 4222, Australia"},{"name":"Institute for Biomedicine and Glycomics, Griffith University, Southport QLD 4222, Australia"},{"name":"Australian Centre for Precision Health and Technology, Griffith University, Southport QLD 4222, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-dong","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Medicine and Dentistry, Griffith University, Gold Coast Campus, QLD 4222, Australia"},{"name":"Institute for Biomedicine and Glycomics, Griffith University, Southport QLD 4222, Australia"},{"name":"The Central Analytical Research Facility, Queensland University of Technology, Brisbane, Queensland, 4000, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6750-9950","authenticated-orcid":false,"given":"Yao","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-bo","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang-hang","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-wei","family":"Xing","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-jia","family":"Han","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-hou","family":"Miao","sequence":"additional","affiliation":[{"name":"School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou 510182, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7447-1097","authenticated-orcid":false,"given":"En","family":"Luo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1785-3491","authenticated-orcid":false,"given":"Yin","family":"Xiao","sequence":"additional","affiliation":[{"name":"School of Medicine and Dentistry, Griffith University, Gold Coast Campus, QLD 4222, Australia"},{"name":"Institute for Biomedicine and Glycomics, Griffith University, Southport QLD 4222, Australia"},{"name":"Australian Centre for Precision Health and Technology, Griffith University, Southport QLD 4222, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6MH00561F\/cit1\/1","doi-asserted-by":"crossref","first-page":"115805","DOI":"10.1016\/j.bone.2020.115805","volume":"144","author":"Talevski","year":"2021","journal-title":"Bone"},{"key":"D6MH00561F\/cit2\/1","doi-asserted-by":"crossref","first-page":"102231","DOI":"10.1016\/j.jcot.2023.102231","volume":"43","author":"Nashi","year":"2023","journal-title":"J. Clin. Orthop. Trauma"},{"key":"D6MH00561F\/cit3\/1","first-page":"7","volume":"2","author":"Olivia","year":"2025","journal-title":"Regener. Med. Dent."},{"key":"D6MH00561F\/cit4\/1","doi-asserted-by":"crossref","first-page":"e2402610","DOI":"10.1002\/adhm.202402610","volume":"14","author":"Yang","year":"2025","journal-title":"Adv. Healthcare Mater."},{"key":"D6MH00561F\/cit5\/1","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/nrd3669","volume":"11","author":"Redlich","year":"2012","journal-title":"Nat. Rev. Drug Discovery"},{"key":"D6MH00561F\/cit6\/1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.actbio.2021.04.052","volume":"133","author":"Schlundt","year":"2021","journal-title":"Acta Biomater."},{"key":"D6MH00561F\/cit7\/1","doi-asserted-by":"crossref","first-page":"116389","DOI":"10.1016\/j.bone.2022.116389","volume":"159","author":"Kim","year":"2022","journal-title":"Bone"},{"key":"D6MH00561F\/cit8\/1","doi-asserted-by":"crossref","first-page":"e2303549","DOI":"10.1002\/adhm.202303549","volume":"13","author":"He","year":"2024","journal-title":"Adv. Healthcare Mater."},{"key":"D6MH00561F\/cit9\/1","doi-asserted-by":"crossref","first-page":"123601","DOI":"10.1016\/j.lfs.2025.123601","volume":"371","author":"Ghamangiz","year":"2025","journal-title":"Life Sci."},{"key":"D6MH00561F\/cit10\/1","doi-asserted-by":"crossref","first-page":"eado6798","DOI":"10.1126\/sciadv.ado6798","volume":"10","author":"Luo","year":"2024","journal-title":"Sci. Adv."},{"key":"D6MH00561F\/cit11\/1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/imr.13214","volume":"319","author":"Schilperoort","year":"2023","journal-title":"Immunol. Rev."},{"key":"D6MH00561F\/cit12\/1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1186\/s12951-025-03363-5","volume":"23","author":"Jiang","year":"2025","journal-title":"J. Nanobiotechnol."},{"key":"D6MH00561F\/cit13\/1","doi-asserted-by":"crossref","first-page":"e2004172","DOI":"10.1002\/adma.202004172","volume":"33","author":"Li","year":"2021","journal-title":"Adv. Mater."},{"key":"D6MH00561F\/cit14\/1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.actbio.2021.03.019","volume":"126","author":"Shen","year":"2021","journal-title":"Acta Biomater."},{"key":"D6MH00561F\/cit15\/1","doi-asserted-by":"crossref","first-page":"105196","DOI":"10.1016\/j.isci.2022.105196","volume":"25","author":"Gao","year":"2022","journal-title":"iScience"},{"key":"D6MH00561F\/cit16\/1","doi-asserted-by":"crossref","first-page":"11488","DOI":"10.1073\/pnas.1714267114","volume":"114","author":"Thamphiwatana","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"D6MH00561F\/cit17\/1","doi-asserted-by":"crossref","first-page":"e2301178","DOI":"10.1002\/smtd.202301178","volume":"8","author":"Qu","year":"2024","journal-title":"Small methods"},{"key":"D6MH00561F\/cit18\/1","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1039\/D1BM01664D","volume":"10","author":"Khatoon","year":"2022","journal-title":"Biomater. Sci."},{"key":"D6MH00561F\/cit19\/1","doi-asserted-by":"crossref","first-page":"105563","DOI":"10.1016\/j.phrs.2021.105563","volume":"167","author":"Gao","year":"2021","journal-title":"Pharmacol.\nRes."},{"key":"D6MH00561F\/cit20\/1","doi-asserted-by":"crossref","first-page":"eaav5086","DOI":"10.1126\/sciadv.aav5086","volume":"5","author":"Kobayakawa","year":"2019","journal-title":"Sci. Adv."},{"key":"D6MH00561F\/cit21\/1","doi-asserted-by":"crossref","first-page":"121321","DOI":"10.1016\/j.biomaterials.2021.121321","volume":"280","author":"Pan","year":"2022","journal-title":"Biomaterials"},{"key":"D6MH00561F\/cit22\/1","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/s10787-020-00690-x","volume":"28","author":"Hariharan","year":"2020","journal-title":"Inflammopharmacology"},{"key":"D6MH00561F\/cit23\/1","doi-asserted-by":"crossref","first-page":"103325","DOI":"10.1016\/j.redox.2024.103325","volume":"76","author":"Bhattarai","year":"2024","journal-title":"Redox Biol."},{"key":"D6MH00561F\/cit24\/1","doi-asserted-by":"crossref","first-page":"34378","DOI":"10.1021\/acsami.3c03446","volume":"15","author":"Chen","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"D6MH00561F\/cit25\/1","doi-asserted-by":"crossref","first-page":"14213","DOI":"10.1021\/acsnano.5c00574","volume":"19","author":"Li","year":"2025","journal-title":"ACS Nano"},{"key":"D6MH00561F\/cit26\/1","doi-asserted-by":"crossref","first-page":"123119","DOI":"10.1016\/j.biomaterials.2025.123119","volume":"318","author":"Chen","year":"2025","journal-title":"Biomaterials"},{"key":"D6MH00561F\/cit27\/1","doi-asserted-by":"crossref","first-page":"e2401620","DOI":"10.1002\/adma.202401620","volume":"36","author":"Zou","year":"2024","journal-title":"Adv. Mater."},{"key":"D6MH00561F\/cit28\/1","doi-asserted-by":"crossref","first-page":"e2201349","DOI":"10.1002\/adhm.202201349","volume":"12","author":"Jing","year":"2023","journal-title":"Adv. Healthcare Mater."},{"key":"D6MH00561F\/cit29\/1","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1021\/acsbiomaterials.4c02263","volume":"11","author":"Yin","year":"2025","journal-title":"ACS Biomater. Sci. Eng."},{"key":"D6MH00561F\/cit30\/1","doi-asserted-by":"crossref","first-page":"8112","DOI":"10.1039\/D2NR02176E","volume":"14","author":"Nie","year":"2022","journal-title":"Nanoscale"},{"key":"D6MH00561F\/cit31\/1","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.jconrel.2025.01.061","volume":"380","author":"Li","year":"2025","journal-title":"J. Controlled Release"},{"key":"D6MH00561F\/cit32\/1","doi-asserted-by":"crossref","first-page":"121114","DOI":"10.1016\/j.biomaterials.2021.121114","volume":"277","author":"Newman","year":"2021","journal-title":"Biomaterials"},{"key":"D6MH00561F\/cit33\/1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.apsb.2017.12.002","volume":"8","author":"Jin","year":"2018","journal-title":"Acta Pharm. Sin. B"},{"key":"D6MH00561F\/cit34\/1","doi-asserted-by":"crossref","first-page":"102241","DOI":"10.1016\/j.arr.2024.102241","volume":"95","author":"Huang","year":"2024","journal-title":"Ageing Res. Rev."},{"key":"D6MH00561F\/cit35\/1","doi-asserted-by":"crossref","first-page":"2703","DOI":"10.2147\/IJN.S298159","volume":"16","author":"Liang","year":"2021","journal-title":"Int. J. Nanomed."},{"key":"D6MH00561F\/cit36\/1","doi-asserted-by":"crossref","first-page":"124139","DOI":"10.1016\/j.biomaterials.2026.124139","volume":"332","author":"Han","year":"2026","journal-title":"Biomaterials"},{"key":"D6MH00561F\/cit37\/1","doi-asserted-by":"crossref","first-page":"4136","DOI":"10.1038\/s41467-021-24447-4","volume":"12","author":"Zhang","year":"2021","journal-title":"Nat. Commun."},{"key":"D6MH00561F\/cit38\/1","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1186\/s12951-022-01746-6","volume":"20","author":"Wu","year":"2022","journal-title":"J. Nanobiotechnol."},{"key":"D6MH00561F\/cit39\/1","doi-asserted-by":"crossref","first-page":"e20240006","DOI":"10.1002\/SMMD.20240006","volume":"3","author":"Li","year":"2024","journal-title":"Smart Med."},{"key":"D6MH00561F\/cit40\/1","doi-asserted-by":"crossref","first-page":"112062","DOI":"10.1016\/j.cellsig.2025.112062","volume":"135","author":"Si","year":"2025","journal-title":"Cell. Signalling"},{"key":"D6MH00561F\/cit41\/1","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1186\/s12951-021-01128-4","volume":"19","author":"Ding","year":"2021","journal-title":"J. Nanobiotechnol."},{"key":"D6MH00561F\/cit42\/1","doi-asserted-by":"crossref","first-page":"e2206200","DOI":"10.1002\/adma.202206200","volume":"34","author":"Feng","year":"2022","journal-title":"Adv. Mater."},{"key":"D6MH00561F\/cit43\/1","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.actbio.2019.02.006","volume":"88","author":"Yang","year":"2019","journal-title":"Acta Biomater."},{"key":"D6MH00561F\/cit44\/1","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.celrep.2016.09.008","volume":"17","author":"Van den Bossche","year":"2016","journal-title":"Cell Rep."},{"key":"D6MH00561F\/cit45\/1","doi-asserted-by":"crossref","first-page":"e20230036","DOI":"10.1002\/SMMD.20230036","volume":"3","author":"Zhao","year":"2024","journal-title":"Smart Med."},{"key":"D6MH00561F\/cit46\/1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s41232-023-00279-1","volume":"43","author":"Kushioka","year":"2023","journal-title":"Inflammation Regener."},{"key":"D6MH00561F\/cit47\/1","doi-asserted-by":"crossref","first-page":"5689","DOI":"10.1038\/s41467-024-50021-9","volume":"15","author":"Li","year":"2024","journal-title":"Nat. Commun."},{"key":"D6MH00561F\/cit48\/1","doi-asserted-by":"crossref","first-page":"e14390","DOI":"10.1111\/acel.14390","volume":"24","author":"Liu","year":"2025","journal-title":"Aging Cell"}],"container-title":["Materials Horizons"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsc.org\/en\/content\/articlepdf\/2026\/MH\/D6MH00561F","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T15:25:16Z","timestamp":1783351516000},"score":1,"resource":{"primary":{"URL":"https:\/\/xlink.rsc.org\/?DOI=D6MH00561F"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":48,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2026,7,6]]}},"URL":"https:\/\/doi.org\/10.1039\/d6mh00561f","relation":{},"ISSN":["2051-6347","2051-6355"],"issn-type":[{"value":"2051-6347","type":"print"},{"value":"2051-6355","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}