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Chem."],"abstract":"<jats:p>A catalyst-free 1,3-dipolar cycloaddition of pyrazolone-derived azomethine ylides with maleimides has been developed, and a series of novel pharmaceutically interesting spiro-pyrazolone-pyrrolizines was obtained in moderate to excellent yields.<\/jats:p>","DOI":"10.1039\/d6ob00014b","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T13:20:53Z","timestamp":1768828853000},"page":"1363-1368","update-policy":"https:\/\/doi.org\/10.1039\/rsc_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A three-component 1,3-dipolar cycloaddition of pyrazolone-derived azomethine ylides with succinimides for the construction of novel spiro-pyrazolone-pyrrolizines containing succinimides"],"prefix":"10.1039","volume":"24","author":[{"given":"Jianming","family":"Xu","sequence":"first","affiliation":[{"name":"Laboratory of Green Catalysis of Higher Education Institutes of Sichuan, College of Chemistry and Environmental Engineering, Sichuan University of Science & Engineering, Zigong 643000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Hu","sequence":"additional","affiliation":[{"name":"Laboratory of Green Catalysis of Higher Education Institutes of Sichuan, College of Chemistry and Environmental Engineering, Sichuan University of Science & Engineering, Zigong 643000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Wang","sequence":"additional","affiliation":[{"name":"Laboratory of Green Catalysis of Higher Education Institutes of Sichuan, College of Chemistry and Environmental Engineering, Sichuan University of Science & Engineering, Zigong 643000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9369-8527","authenticated-orcid":false,"given":"Song","family":"Hu","sequence":"additional","affiliation":[{"name":"Laboratory of Green Catalysis of Higher Education Institutes of Sichuan, College of Chemistry and Environmental Engineering, Sichuan University of Science & Engineering, Zigong 643000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Yin","sequence":"additional","affiliation":[{"name":"Laboratory of Green Catalysis of Higher Education Institutes of Sichuan, College of Chemistry and Environmental Engineering, Sichuan University of Science & Engineering, Zigong 643000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5579-3269","authenticated-orcid":false,"given":"Yulong","family":"Li","sequence":"additional","affiliation":[{"name":"Laboratory of Green Catalysis of Higher Education Institutes of Sichuan, College of Chemistry and Environmental Engineering, Sichuan University of Science & Engineering, Zigong 643000, China"},{"name":"Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), Nankai University, Tianjin 300071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8344-215X","authenticated-orcid":false,"given":"Chenyi","family":"Li","sequence":"additional","affiliation":[{"name":"Laboratory of Green Catalysis of Higher Education Institutes of Sichuan, College of Chemistry and Environmental Engineering, Sichuan University of Science & Engineering, Zigong 643000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"292","published-online":{"date-parts":[[2026]]},"reference":[{"key":"D6OB00014B\/cit1a\/1","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1002\/cmdc.200600026","volume":"1","author":"Manetti","year":"2006","journal-title":"ChemMedChem"},{"key":"D6OB00014B\/cit1b\/1","doi-asserted-by":"crossref","first-page":"8587","DOI":"10.1016\/j.bmc.2008.08.016","volume":"16","author":"Castagnolo","year":"2008","journal-title":"Bioorg. 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